Red cell transfusion practice following the transfusion requirements in critical care (TRICC) study: prospective observational cohort study in a large UK intensive care unit.

abstract：:beta 2-Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions beta 2-microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the c...

journal_title：Vox sanguinis

authors： Bernier GM

更新日期：1980-06-01 00:00:00

abstract：:Red cells of the McLeod phenotype in the Kell blood group system have an acanthocytic morphology. The membrane protein composition analyzed on sodium dodecyl-sulfate-polyacrylamide gel electrophoresis, the ATP level and the activities of a large number of intracellular enzymes appear to be normal. Membranes prepared f...

journal_title：Vox sanguinis

authors： Tang LL,Redman CM,Williams D,Marsh WL

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:White blood cell (WBC) fragments in platelet concentrates (PCs) may induce allo-immunization in the recipient. MATERIALS AND METHODS:As the level of WBC fragments can differ between PCs produced using different methods, we compared PCs prepared by using the buffy-coat method (BC-PCs) in plasm...

journal_title：Vox sanguinis

authors： Dijkstra-Tiekstra MJ,van der Schoot CE,Pietersz RN,Reesink HW

更新日期：2005-05-01 00:00:00

abstract：:The classic enzyme-linked antiglobulin test (ELAT) used to detect and quantify the amount of IgG antibodies on red blood cells (RBC) is sensitive to hemolysis and erythrocyte enzymatic activities. We describe a new ELAT by using glucose oxidase (GO) linked to antihuman IgG. The optical density base line of GO-ELAT, al...

journal_title：Vox sanguinis

authors： Rigal D,Monestier M,Lafont S,Raffin T,Got A,Meyer F,Jouvenceaux A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study was undertaken to provide denominator data relating to the timing and location of transfusion, to support interpretation of reports of incorrect blood component transfused (IBCT) events to the UK Serious Hazards of Transfusion (SHOT) scheme. MATERIALS AND METHODS:The study was carr...

journal_title：Vox sanguinis

authors： Tinegate HN,Thompson CL,Jones H,Stainsby D

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to asse...

journal_title：Vox sanguinis

authors： Bugge HF,Karlsen NC,Oydna E,Rake MM,Wexels N,Bendabenda J,Roald B,Heier HE,Chisuwo L,Jourdan PM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：:Platelet function in thrombosis and haemostasis is reasonably well understood at the molecular level with respect to the proteins involved in cellular structure, signalling networks and platelet interaction with clotting factors and other cells. However, the natural history of these proteins has only recently garnered...

journal_title：Vox sanguinis

authors： Schubert P,Devine DV

更新日期：2010-08-01 00:00:00

abstract：:This report describes the recovery of highly purified immune-serum globulin (ISG) from the 42% ethanol precipitate fraction (42% P) generated during the first step of albumin purification. The method consists of three purification steps: (1) reprecipitation of the 42% P at 20% ethanol, pH 7.2; (2) solubilization of IS...

journal_title：Vox sanguinis

authors： Hao YL,Wickerhauser M

更新日期：1981-04-01 00:00:00

abstract：:An attempt was made to confirm a previously reported association between HLA type B16 and resistance to infection with live attenuated influenza A virus vaccine. No differences were found either in the ability of influenza virus to attach to fractionated white blood cells from HLB B16 subjects compared to cells from s...

journal_title：Vox sanguinis

authors： Mackenzie JS,Wetherall JD,Flower RL,Fimmel PJ,Dawkins RL

更新日期：1979-01-01 00:00:00

abstract：:Hepatitis A virus (HAV) infections have been reported among hemophiliacs who received factor VIII concentrates which had been purified by ion-exchange chromatography and treated by the solvent detergent (SD) method. Since the virus inactivation procedure of our manufacturing process is heat treatment of the stabilized...

journal_title：Vox sanguinis

authors： Hilfenhaus J,Nowak T

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:In Europe, buffy-coat processing allows for the use of platelet additive solutions (PAS). These solutions, however, have long been questioned for their lack of glucose, a potentially essential nutrient for platelet storage. Using a novel, practical, two-part system for incorporation of glucose into an additi...

journal_title：Vox sanguinis

authors： Gyongyossy-Issa MI,Zhang JG,Culibrk B,Hunter F,Levin E,Scammell K,Weiss S,Holmes DL,Holme S

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The amino acid substitutions caused by ABO gene variants are usually predicted to impact the glycosyltransferase function. Here, the effect of an amino acid substitution in the vicinity of the catalytic active region of the B-glycosyltransferase was explored in vitro and in silico study, which is important f...

journal_title：Vox sanguinis

authors： Ying Y,Hong X,Xu X,Zhang J,He J,Zhu F,Xie X

更新日期：2020-12-16 00:00:00

abstract：:Previously described methods of phenotyping red cells sensitised with IgG using the indirect antiglobulin test required the dissociation of the coating protein. Based on an entirely different principle, Fab fragments of anti-human IgG (Fab anti-IgG) were used to block the antiglobulin binding sites on cell-bound IgG m...

journal_title：Vox sanguinis

authors： Henry SM,Baird SJ,Woodfield DG

更新日期：1987-01-01 00:00:00

abstract：:To maximize the availability of platelet concentrates (PC) and minimize their outdate, competing criteria, a computer simulation model of platelet production and distribution was developed. Based on 2 years of actual platelet orders placed with a regional blood center, the simulation program generated daily platelet o...

journal_title：Vox sanguinis

authors： Katz AJ,Carter CW,Saxton P,Blutt J,Kakaiya RM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Analysis of reports of incidents, involving ABO incompatibility suggests that the main problem is poor interpretation of the pretransfusion bedside compatibility test (PBCT). We studied sources of error as experienced by nurses as to the blood groups of donor blood and of the recipient. MATERI...

journal_title：Vox sanguinis

authors： Dujardin PP,Salmi LR,Ingrand P

更新日期：2000-01-01 00:00:00

abstract：:The effect of gamma irradiation on HIV and plasma coagulation factors F VIII:C, F VIII:vWF and FIX was studied. Donor plasma was harvested from single donations, frozen and irradiated in the frozen state at target doses from 0 to 40 kGy (0-4 mRad). HIV was inoculated into human plasma and irradiated in a similar manne...

journal_title：Vox sanguinis

authors： Kitchen AD,Mann GF,Harrison JF,Zuckerman AJ

更新日期：1989-01-01 00:00:00

abstract：:We have employed a PCR approach to determine the nucleotide sequences of the coding region in the last two coding exons of the histo-blood group ABO genes from one A(X) and one B(A) individual. Compared with A1 alleles, the (A(X)) allele has a single nucleotide substitution (T-->A at nucleotide 646) resulting in an am...

journal_title：Vox sanguinis

authors： Yamamoto F,McNeill PD,Yamamoto M,Hakomori S,Harris T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion based on the Thrombelastograph (TEG) results reduces transfusion requirements in cardiac surgery and in liver transplantation. Taking the pivotal role of thrombin generation in the coagulation process into consideration, the clinical utility of the TEG may, in part, depend on its r...

journal_title：Vox sanguinis

authors： Johansson PI,Svendsen MS,Salado J,Bochsen L,Kristensen AT

更新日期：2008-02-01 00:00:00

abstract：:This study reports the adaptation of an electronic particle-counting method for the enumeration of T cell and B cell rosettes of human lymphocytes. This method and the conventional hemocytometer method were compared in parallel on seventeen T cell and seven B cell rosette enumerations in a blind study design. All data...

journal_title：Vox sanguinis

authors： Denny TN,Kinsley KM,Benson JW,Bull RW

更新日期：1979-01-01 00:00:00

abstract：:The interaction of temperature and pH in biological systems comprises two components. Temperature change may perturb the pH of solutions, and it may change the pKa of some ionizable groups that are involved in enzyme catalysis. The pH optima of single reactions and whole pathways are therefore temperature sensitive. T...

journal_title：Vox sanguinis

authors： Guppy M,Attwood PV,Hansen IA,Sabaratnam R,Frisina J,Whisson ME

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...

journal_title：Vox sanguinis

authors： Beckman N,Cardigan R,Wallington T,Williamson LM

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Changes in in vitro platelet quality parameters during platelet storage are associated with a decrease of in vivo platelet viability after platelet transfusion. Many attempts have been made to identify the most predictable in vitro parameters for in vivo performance. We used a riboflavin-based...

journal_title：Vox sanguinis

authors： Goodrich RP,Li J,Pieters H,Crookes R,Roodt J,Heyns Adu P

更新日期：2006-05-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：:Little is known about the patient's reasons for participating in an autologous blood (AUB) collection program. We surveyed 110 AUB donors in our hospital-based collection program. Although fear of infection from an allogeneic blood transfusion was cited by 20% of AUB donors, 68.2% indicated that their physician's reco...

journal_title：Vox sanguinis

authors： Domen RE,Ribicki LA,Hoeltge GA

更新日期：1995-01-01 00:00:00

abstract：:The mechanism of CD4+ lymphocyte depletion, which is the main immunological feature in HIV-infected patients, is unclear. We investigated whether gp120-immunoglobulin-complement complexes on the surface of CD4+ cells might be involved in the elimination of CD4+ lymphocytes. The results obtained in 63 HIV-infected pati...

journal_title：Vox sanguinis

authors： Daniel V,Süsal C,Prodeus AP,Weimer R,Zimmermann R,Huth-Kühne A,Opelz G

更新日期：1993-01-01 00:00:00

abstract：:A substantial body of animal data indicates that transmissible spongiform encephalopathies (TSEs) are transmitted through blood. These data have been augmented in the past year by reports that two recipients of red cells from donors with variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom have acquired this...

journal_title：Vox sanguinis

authors： Farrugia A,Ironside JW,Giangrande P

更新日期：2005-11-01 00:00:00

abstract：:Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 Amazon...

journal_title：Vox sanguinis

authors： Franco RF,Simões BP,Guerreiro JF,Santos SE,Zago MA

更新日期：1994-01-01 00:00:00

abstract：:Three examples of an antibody were found to be detecting a red cell polymorphism probably identical to MER2. The antibodies were made by Jews originating from India and living in Israel. Two of them were sibs and the third was unrelated. All 3 had kidney disease requiring renal dialysis and regular blood transfusion. ...

journal_title：Vox sanguinis

authors： Daniels GL,Levene C,Berrebi A,Schechter Y,Moulds M,Sela R,Poole J,Lacey P,Atkins CJ

更新日期：1988-01-01 00:00:00

abstract：:Sera from 2,829 participants in a population health survey were tested for the presence of a heterophilic antibody, detectable by immunofluorescence. The antibody was found in 9.8% of the sera from women and in 12.4% of the sera from men. The age-specific prevalence of the antibody was relatively constant in women but...

journal_title：Vox sanguinis

authors： Hawkins BR,Saueracker GC,Dawkins RL,Davey MG,O'Connor KJ

更新日期：1980-12-01 00:00:00