Investigation of the thrombin-generating capacity, evaluated by thrombogram, and clot formation evaluated by thrombelastography of platelets stored in the blood bank for up to 7 days.

abstract：BACKGROUND AND OBJECTIVES:The International Haemovigilance Network collects aggregate data on complications of blood donation from member haemovigilance systems (HVS). We analysed the data collected in 2006-2016 in order to learn from it and consider future improvements. MATERIALS AND METHODS:National HVS entered annu...

journal_title：Vox sanguinis

authors： Wiersum-Osselton JC,Politis C,Richardson C,Goto N,Grouzi E,Marano G,Land KJ

更新日期：2020-12-05 00:00:00

abstract：:Significantly more peripheral blood mononuclear cells (PBM) from 39 patients with lymphoma (p less than 0.001), myeloma (p less than 0.001), or leukemia (p less than 0.001-0.025) bind transferrin (Trf) than those of 23 normals. That Trf was bound to a receptor on these cells was shown by the inhibition of these cells ...

journal_title：Vox sanguinis

authors： Yeh CJ,Taylor CG,Faulk WP

更新日期：1984-01-01 00:00:00

abstract：:The human Lewis gene encodes an alpha(1,3/1,4)-fucosyltransferase responsible for synthesis of the Le(a) and a Le(b) antigens. To define the molecular background for non-functional Lewis genes we have sequenced PCR-amplified DNA fragments from two Le(a-b-) individuals. One was homozygously mutated at nucleotides 202(T...

journal_title：Vox sanguinis

authors： Elmgren A,Börjeson C,Svensson L,Rydberg L,Larson G

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Partially replacing plasma with additive solutions in platelet (PLT) concentrates (PCs) may help to reduce transfusion reactions. Constituents of PLT additive solutions (PASs) have been revealed to affect the quality of PCs. Previous studies involved pairwise comparison of identical PLTs with ...

journal_title：Vox sanguinis

authors： Nogawa M,Naito Y,Chatani M,Onodera H,Shiba M,Okazaki H,Matsuzaki K,Satake M,Nakajima K,Tadokoro K

更新日期：2013-11-01 00:00:00

abstract：:The second International Society of Blood Transfusion and International Council for Standardization in Haematology workshop on molecular blood group genotyping was held in 2006. Forty-one laboratories participated. Six samples were distributed: two representing DNA from transfusion-dependent patients for testing for a...

journal_title：Vox sanguinis

authors： Daniels G,van der Schoot CE,Olsson ML

更新日期：2007-07-01 00:00:00

abstract：:A model of the Rh blood group system is proposed which is based on discontinuous gene structure. The R29 control subregion consists of a single exon flanked by introns. Following the R29 subregion, the R1 subregion exists as seven exon structures which alternate with introns. The expression of each exon is controlled ...

journal_title：Vox sanguinis

authors： Giorno R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, Héma-Québec is considering the possibility of allowing men who have sex with men (MSM) to donate plasma for fractionation combined with a mandatory quarantine period. This study aims to assess the acceptability and operational feasibility of the programme in the targeted population....

journal_title：Vox sanguinis

authors： Caruso J,Germain M,Godin G,Myhal G,Pronovost F,Morin M,Otis J

更新日期：2019-10-01 00:00:00

abstract：:Blood transfusion practices have evolved empirically, with few or no research data supporting them. In the past several decades, fuelled by fears of infection and reports of mistakes, patients have increasingly demanded their rights to choice, both in the components given to them as well as to refuse to receive these ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：2007-02-01 00:00:00

abstract：:A method is described for the production of mouse monoclonal antibodies to HBsAg. 4 clones produced antibodies directed at the a and one at the d determinant of HBsAg. These antibodies were conjugated to horse radish peroxidase and used in an Elisa for the detection of HBsAg in donated blood. Antibody C10 produced con...

journal_title：Vox sanguinis

authors： Els MC,Govender M,Marimuthu T,Bubb MO,Conradie JD

更新日期：1984-01-01 00:00:00

abstract：:Following transfusion, red cells labeled with nonradioactive chromium (52Cr) can be detected in the circulation using atomic absorption spectrophotometry. Both in rhesus monkeys and in human subjects, the survival of red cells labeled with 52Cr was found to be insignificantly different from that of cells labeled with ...

journal_title：Vox sanguinis

authors： Sioufi HA,Button LN,Jacobson MS,Kevy SV

更新日期：1990-01-01 00:00:00

abstract：:The Gm allotype constitution of the autoantibody molecules and the serum Gm phenotypes were determined in 19 patients with autiommune hemolytic anemia of IgG type. The results showed that the known heterogeneity of the antierythrocyte autoantibodies in this disease concerns not only the immunoglobulin class and the is...

journal_title：Vox sanguinis

authors： Le Petit JC,Rivat L,François N,Ropartz C,Brizard CP

更新日期：1976-01-01 00:00:00

abstract：:Four Kp(a-b-) Japanese sisters, the product of a consanguineous mating, have otherwise normal Kell antigens. Kpc, a 'new' allele of Kpa and Kpb is the most probable background. ...

journal_title：Vox sanguinis

authors： Yamaguchi H,Okubo Y,Seno T,Matsushita K,Daniels GL

更新日期：1979-01-01 00:00:00

abstract：:We developed a photodynamic method to inactivate viruses in human fresh plasma. Single plasma bags were illuminated with visible light in the presence of low doses of phenothiazine dyes like methylene blue or toluidine blue. By this treatment the infectivity of different enveloped viruses including the causative agent...

journal_title：Vox sanguinis

authors： Lambrecht B,Mohr H,Knüver-Hopf J,Schmitt H

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Parvovirus B19 (B19V) DNA seems to persist in the plasma of B19V-infected blood donors. The relevance of this for recipients of single-donor blood components is yet unclear. MATERIAL AND METHODS:We studied serial archive and follow-up samples from 75 B19V-infected blood donors to obtain more ...

journal_title：Vox sanguinis

authors： Juhl D,Görg S,Hennig H

更新日期：2014-10-01 00:00:00

abstract：:Aliquots of 130 HB8Ag negative units of blood which were administered to 26 recipients were tested under code for anti-HBc by a solid phase radioimmunoassay technqiue. 14 of the 26 recipients developed posttransfusion hepatitis (PTH), including 6 cases of hepatitis B. Anti-HBc was detected in 7 or 5.3% of 130 donor un...

journal_title：Vox sanguinis

authors： Lander JJ,Gitnick GL,Gelb LH,Aach RD

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：:A non-blow-molded LE-2 polyolefin (PO) container was developed to store single-donor apheresis platelet concentrates (PCs) processed by the Haemonetics Plasma Collecting System (PCS) at 22 degrees C for over 1 day. We molded PO containers with heat-sealing of light-weight polymer alloy films with a thickness of 0.25 m...

journal_title：Vox sanguinis

authors： Shimizu T,Kouketsu K,Kamiya T,Futagawa H,Hirose S

更新日期：1989-01-01 00:00:00

abstract：:The storage of fresh frozen plasma (FFP) for short periods at -20 degrees C for 6 weeks, -30 degrees C for 12 weeks, or -40 degrees C for 12 weeks, did not result in significant deterioration in factor VIII: coagulant (factor VIII:C) activity in the primary packs. In studies examining whether plasma segments could be ...

journal_title：Vox sanguinis

authors： Ofosu FA,Blajchman MA,Kaegi A,Turc JM

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion of fresh-frozen plasma is still a pillar in emergency medicine for using to prevent dilutional coagulopathy or disseminated intravascular coagulation after severe blood loss, but thawing procedures can delay its availability. On the other hand, the wastage of plasma, once thawed an...

journal_title：Vox sanguinis

authors： Buchta C,Felfernig M,Höcker P,Macher M,Körmöczi GF,Quehenberger P,Heinzl H,Knöbl P

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several pathogen inactivation methods currently applied to therapeutic plasma may result in products with different hemostatic properties. This study aims at evaluating and comparing the hemostatic potential of different therapeutic plasma preparations currently available in France. MATERIALS...

journal_title：Vox sanguinis

authors： Hacquard M,Lecompte T,Belcour B,Geschier C,Jacquot C,Jacquot E,Schneider T

更新日期：2012-05-01 00:00:00

abstract：:This study describes a new method for comparison of fluid motion and associated shear forces with various modes of platelet agitation. Fluid motion generated by flatbed, tumbler-type and circular platelet agitators was investigated. Trajectory tracings of polyethylene beads suspended inside platelet storage bags were ...

journal_title：Vox sanguinis

authors： Torres R,Tormey CA,Stack G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent studies suggest that transfusion of old red blood cell (RBC)s, mainly those close to the 42-day maximum shelf life (MSL), is associated with increased morbi-mortality. Although there is no formal proof supporting a causal relationship, the precautionary principle asks for corrective inte...

journal_title：Vox sanguinis

authors： Grasas A,Pereira A,Bosch MA,Ortiz P,Puig L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：:Prothrombin complex concentrates prepared for clinical use are reviewed with emphasis on frequently observed adverse reactions such as viral hepatitis and thromboembolic complications. Preparation procedures and quality control are described briefly, and the use of these concentrates in the treatment of hemophilia A p...

journal_title：Vox sanguinis

authors： Chandra S,Brummelhuis HG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Blood transfusions can transmit parasitic infections, such as those caused by Plasmodium (malaria), Trypanosoma cruzi (Chagas' disease), and Babesia (babesiosis). A higher degree of blood transfusion safety would be reached if methods were available for inactivating such parasites. MATERIALS ...

journal_title：Vox sanguinis

authors： Grellier P,Santus R,Mouray E,Agmon V,Mazière JC,Rigomier D,Dagan A,Gatt S,Schrével J

更新日期：1997-01-01 00:00:00

abstract：:Tissue oxygen delivery depends on red blood cell (RBC) content and RBC flow regulation in the microcirculation. The important role of the RBC in tissue oxygenation is clear from anaemia and the use of RBC transfusion which has saved many lives. Whether RBC transfusion actually restores tissue oxygenation is difficult ...

journal_title：Vox sanguinis

authors： Raat NJ,Ince C

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite long being a mainstay in describing platelet activation via degranulation, interlaboratory variation remains an issue in measurement of membrane CD62P by flow cytometry. Our objective was to identify actions that may minimize this variation. MATERIALS AND METHODS:Sixteen laboratories ...

journal_title：Vox sanguinis

authors： Levin E,Serrano K,Devine DV,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2013-07-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：:We tested serum samples from 11 HIV-seropositive and 32 HIV-seronegative Italian patients with hemophilia A or B for the presence of lymphocytotoxic antibodies (LCTAs). No patients had the acquired immune deficiency syndrome and all had received over many years heat-untreated commercial clotting factors. LCTAs directe...

journal_title：Vox sanguinis

authors： Conte R,Giovanardi L,Tazzari PL,De Rosa V,Rodorigo G,Re MC

更新日期：1988-01-01 00:00:00

abstract：:The results of testing RoHarr cells with panels of monoclonal anti-D suggest that the D antigen (referred to as DHar) encoded by the haplotype (D)c(e) Rh33 is a partial D antigen. IgM monoclonal anti-D are more efficient than IgG monoclonal anti-D in detecting DHar.DHar expresses some but not all of both epD5 and epD6...

journal_title：Vox sanguinis

authors： Wallace M,Lomas-Francis C,Tippett P

更新日期：1996-01-01 00:00:00