Mechanism evaluation for an amino acid substitution p.Y246C of B-glycosyltransferase enzyme with Bweak phenotype.

abstract：:A method to coat unsensitized erythrocytes with fragments of C3 and C4 using autologous serum, in order to study complement receptor-dependent function of the fixed macrophage system, is presented. After incubation with serum under optimal conditions, at least 90% of the cells had C3b/iC3b deposited on the surface, wi...

journal_title：Vox sanguinis

authors： Nilsson Ekdahl K,Lööf L,Nilsson UR,Nilsson B

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

journal_title：Vox sanguinis

authors： Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:A disposable set for platelet concentrate (PC) preparation by the buffy coat method allows pooling of buffy coats, centrifugation and cell separation with in-line leucocyte filtration. This study compares three commercially available pooling sets in combination with INTERCEPT pathogen inactivation (PI). MAT...

journal_title：Vox sanguinis

authors： Feys HB,Devloo R,Sabot B,Coene J,Compernolle V

更新日期：2018-05-24 00:00:00

abstract：:The thermal stabilization of human albumin by caprylate (CA) and acetyltryptophanate (AT) was studied by monitoring the formation of albumin polymer (defined as species larger than dimer) on the basis of its molecular size as well as its characteristic migration as alpha-globulin. Heating 5% protein solutions of purif...

journal_title：Vox sanguinis

authors： Yu MW,Finlayson JS

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion of fresh-frozen plasma is still a pillar in emergency medicine for using to prevent dilutional coagulopathy or disseminated intravascular coagulation after severe blood loss, but thawing procedures can delay its availability. On the other hand, the wastage of plasma, once thawed an...

journal_title：Vox sanguinis

authors： Buchta C,Felfernig M,Höcker P,Macher M,Körmöczi GF,Quehenberger P,Heinzl H,Knöbl P

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Donor plasmapheresis involves the removal of a weight-adjusted volume of plasma and the return of cellular components to the donor. Although plasma volume generally returns to normal, some residual effect on vital signs may be possible. This analysis was performed to determine the possible eff...

journal_title：Vox sanguinis

authors： Rosa-Bray M,Wisdom C,Marier JF,Mouksassi MS,Wada S

更新日期：2015-01-01 00:00:00

abstract：:Direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (ITP) revealed positive staining on the surface of platelets for both immunoglobulins (Igs) and human B1C globulin in 9 specimens, for only Igs in 1 specimen and for human B1C alone in 5 specime...

journal_title：Vox sanguinis

authors： Boonpucknavig S,Vuttivirojana O,Srichaikul T

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:One of the challenges surrounding blood component administration is the determination of an appropriate rate of infusion. There are very few evidence-based guidelines available to guide healthcare providers looking for a 'standard' infusion rate for red blood cells (RBCs), plasma or platelets ...

journal_title：Vox sanguinis

authors： Gehrie EA,Hendrickson JE,Tormey CA

更新日期：2015-11-01 00:00:00

abstract：:A method of pasteurising a concentrate of factor I (C3b inactivator) prepared from human blood plasma is described. As well as obtaining a high yield of factor I by this virus inactivation procedure it is furthermore possible, by adjustment of the stabiliser concentration, to obtain a very pronounced reduction in the ...

journal_title：Vox sanguinis

authors： Alsøe KO,Kihl J

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is sometimes difficult to obtain antigen-negative red blood cells (RBCs) for patients with antibodies against RBCs. However, the frequency and severity of the adverse reactions have not been well elucidated. Here, we conducted a multi-institutional collaborative study to clarify the backgro...

journal_title：Vox sanguinis

authors： Yamada C,Takeshita A,Ohto H,Ishimaru K,Kawabata K,Nomaguchi Y,Haraguchi Y,Abe M,Sobue K,Takenouchi H,Takadate J,Kamimura M,Katai A,Kasai D,Minami Y,Sugimoto T,Michino J,Nagai K,Kumagai M,Hasegawa Y,Ishizuka K,Oh

更新日期：2020-07-01 00:00:00

abstract：:We investigated the effects of gravitational force and three different plastic formulations of the storage bags on the quality of stored platelets by measuring the changes in platelet-associated immunoglobulin G (IgG) and two antigenic markers of the third component of human complement (C3), C3d and C3c. Pooled platel...

journal_title：Vox sanguinis

authors： Szymanski IO,Odgren PR,Teno RA,Jacobson MS,Surgenor DM

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To prove the feasibility of a semi-automated cross-match procedure using a commercially available solid-phase microplate test and standard laboratory equipment. MATERIAL AND METHODS:The new procedure was evaluated against the conventional spin tube technique and the gel centrifugation system....

journal_title：Vox sanguinis

authors： Ostendorf N,Niefhoff D,Cassens U,Sibrowski W

更新日期：2001-05-01 00:00:00

abstract：:An autoantibody mimicking anti-S specificity is described in an S-s+ patient. The antibody was detected 2 weeks after transfusion. The direct antiglobulin test (DAT) was positive and the antibody was thought to be an alloantibody formed after the transfusion. Eighteen months later, the DAT was still positive and anti-...

journal_title：Vox sanguinis

authors： Puig N,Carbonell F,Soler MA,Perez MT,Arriaga F,Marty ML

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Human platelet growth factors (HPGF) are essential for tissue regeneration and may replace fetal bovine serum (FBS) in cell therapy. No method for the manufacture of standardized virally inactivated HPGF has been developed yet. STUDY DESIGN AND METHODS:Platelet concentrates (PC) were subjected to solvent/de...

journal_title：Vox sanguinis

authors： Su CY,Kuo YP,Lin YC,Huang CT,Tseng YH,Burnouf T

更新日期：2009-08-01 00:00:00

abstract：:The functional antibacterial activity of an intravenous immunoglobulin preparation (Swiss Red Cross Immunoglobulin, SRK-Ig) was tested both in vitro and in vivo. Using type III group B streptococci as a model system, the intravenous immunoglobulin preparation was shown to enhance phagocytosis and killing of the bacter...

journal_title：Vox sanguinis

authors： Fischer GW,Hunter KW,Hemming VG,Wilson SR

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hepcidin is the main hormone that regulates iron balance. Its lowering favours digestive iron absorption in cases of iron deficiency or enhanced erythropoiesis. The careful dosage of this small peptide promises new diagnostic and therapeutic strategies. Its measurement is progressively being v...

journal_title：Vox sanguinis

authors： Waldvogel S,Rochat B,Peduzzi D,Vaucher P,Tissot JD,Favrat B

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated blood donation produces iron deficiency. Changes in dietary iron intake do not prevent donation-induced iron deficiency. Prolonging the interdonation interval or using oral iron supplements can mitigate donation-induced iron deficiency. The most effective operational methods for reduc...

journal_title：Vox sanguinis

authors： Bialkowski W,Bryant BJ,Schlumpf KS,Wright DJ,Birch R,Kiss JE,D'Andrea P,Cable RG,Spencer BR,Vij V,Mast AE

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Transfusion Requirements In Critical Care (TRICC) study found that critically ill patients tolerate a restrictive haemoglobin transfusion threshold. We investigated red-cell transfusion practice since publication of the TRICC study in a large Scottish teaching hospital intensive care unit ...

journal_title：Vox sanguinis

authors： Chohan SS,McArdle F,McClelland DB,Mackenzie SJ,Walsh TS

更新日期：2003-04-01 00:00:00

abstract：:Recessively inherited ovalocytosis in coastal Melanesians is associated with widespread, but selective, depression of blood group antigens in homozygotes, who comprise about 15% of these populations. It is suggested that a membrane anomaly exists, and that the series of depressed determinants all depend, for their ful...

journal_title：Vox sanguinis

authors： Booth PB,Serjeantson S,Woodfield DG,Amato D

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In a preliminary study, the presence of potassium and magnesium in a modified synthetic medium (PAS-III) was found to have a significant influence on platelet metabolism (using apheresis-derived, as well as buffy-coat-derived platelets) when compared with standard PAS-III. The differences incl...

journal_title：Vox sanguinis

authors： Gulliksson H,AuBuchon JP,Cardigan R,van der Meer PF,Murphy S,Prowse C,Richter E,Ringwald J,Smacchia C,Slichter S,de Wildt-Eggen J

更新日期：2003-10-01 00:00:00

abstract：:Platelet concentrates were prepared in plastic packs of polyvinyl chloride with tri(2-ethylhexyl) trimellitate as plasticizer. They were stored, with gentle shaking, at room temperature for periods up to 7 days before labelling with isotope and reinfusing. In vivo survival studies, platelet counts, pH and electron mic...

journal_title：Vox sanguinis

authors： Archer GT,Grimsley PG,Jindra J,Robson JE,Ribeiro A

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this review was to summarize the properties of the commonly available resuscitation fluids and highlight where knowledge of the characteristics of individual fluids might guide their use in clinical practice. Some of the current controversies surrounding resuscitation fluids are als...

journal_title：Vox sanguinis

authors： Grocott MP,Hamilton MA

更新日期：2002-01-01 00:00:00

abstract：:Serum from a pregnant woman with the May-Hegglin anomaly contained a platelet-specific antibody. The serum reacted in the platelet indirect immunofluorescence test (PIIFT) with 97.6% of random donor platelets and those of the father but not with the mother's own platelets. This antibody induced a moderate thrombocytop...

journal_title：Vox sanguinis

authors： Bettaieb A,Fromont P,Rodet M,Godeau B,Duedari N,Bierling P

更新日期：1991-01-01 00:00:00

abstract：:A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are ...

journal_title：Vox sanguinis

authors： Mayer S,Hauptmann G,Tongio MM

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In this EQA study a novel approach was used to assess the performance of blood centres and blood product manufacturers in detecting the possible contamination of plasma with HCV, HIV and HBV by NAT. MATERIALS AND METHODS:A panel of 12 samples, three negative and three positive for each virus,...

journal_title：Vox sanguinis

authors： Pisani G,Marino F,Cristiano K,Bisso GM,Mele C,Luciani F,Wirz M,Gentili G,External Quality Assessment Participants.

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:An Australian Caucasian blood donor consistently presented a serology profile for the Duffy blood group as Fy(a+b+) with Fy(a) antigen expression weaker than other examples of Fy(a+b+) red cells. Molecular typing studies were performed to investigate the reason for the observed serology profil...

journal_title：Vox sanguinis

authors： Lopez GH,Condon JA,Wilson B,Martin JR,Liew YW,Flower RL,Hyland CA

更新日期：2015-01-01 00:00:00

abstract：:False-positive enzyme immunoassay (EIA) tests in blood donors receiving influenza vaccine were first reported in 1991. We conducted follow-up testing for 6 months of those donors with multiply reactive, but unconfirmed EIA (at least 2 positives in anti-HCV-1.0, anti-HIV-1, and anti-HTLV-I assays) with a history of rec...

journal_title：Vox sanguinis

authors： Arnold NL,Slade BA,Jones MM,Popovsky MA

更新日期：1994-01-01 00:00:00

abstract：:This study describes a new method for comparison of fluid motion and associated shear forces with various modes of platelet agitation. Fluid motion generated by flatbed, tumbler-type and circular platelet agitators was investigated. Trajectory tracings of polyethylene beads suspended inside platelet storage bags were ...

journal_title：Vox sanguinis

authors： Torres R,Tormey CA,Stack G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...

journal_title：Vox sanguinis

authors： Borzini P,Riva M,Nembri P,Rossi E,Pagliaro P,Vergani P,Greppi P,Tantardini P

更新日期：1997-01-01 00:00:00