Abstract:
:A method of pasteurising a concentrate of factor I (C3b inactivator) prepared from human blood plasma is described. As well as obtaining a high yield of factor I by this virus inactivation procedure it is furthermore possible, by adjustment of the stabiliser concentration, to obtain a very pronounced reduction in the concentration of factor B, a component of the complement system which is unwanted in the treatment of factor I deficiency. The product so produced is in two respects superior to plasma infusions for factor I replacement therapy: it has been submitted to virus inactivation and factor B depletion.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Alsøe KO,Kihl Jdoi
10.1111/j.1423-0410.1989.tb00835.xsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
240-2issue
4eissn
0042-9007issn
1423-0410journal_volume
57pub_type
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