Posttransfusion non-A, non-B hepatitis after cardiac surgery: a prospective study.

Abstract:

:In a prospective study of 50 recipients of HBsAg-negative blood who had undergone cardiac surgery, 4 (8%) developed acute non-A, non-B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the disease was 4-13 weeks, 3 patients were asymptomatic with peak alaminotransferase (ALT) levels of 320-497 U/1 and 1 patient was jaundiced with a peak ALT of 3,400 U/1. 1 of the patients had high ALT levels after 21 weeks of observation, while 3 patients recovered after 7-10 weeks. It is concluded that non-A, non-B posttransfusion hepatitis in Israel is a medical problem similar to that in the USA and that the clinical picture of the disease varies from a mild asymptomatic to a symptomatic and protracted course.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Tur-Kaspa R,Shimon DV,Shalit M,Adler R,Shraga S,Manny N,Morag A,Eliakim M

doi

10.1111/j.1423-0410.1983.tb01919.x

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

312-5

issue

4

eissn

0042-9007

issn

1423-0410

journal_volume

45

pub_type

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