A semi-continuous method for purification of factor IX complex from human plasma.

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Allergic transfusion reactions (ATRs) and febrile non-haemolytic transfusion reactions (FNHTRs) are the two major types of transfusion-related adverse reactions (TRARs). Although prestorage leucocyte reduction and diversion of the first aliquot of blood (LR/D) could reduce FNHTRs and bacterial...

journal_title：Vox sanguinis

authors： Yanagisawa R,Shimodaira S,Sakashita K,Hidaka Y,Kojima S,Nishijima F,Hidaka E,Shiohara M,Nakamura T

更新日期：2016-05-01 00:00:00

abstract：:Intra-operative blood cell salvage (IOCS) is mainly avoided in onco surgery due to the suspicion that it could increase metastasis' risk. We simulated IOCS followed by leucodepletion: HCT116 (human colorectal cancer) cells were inoculated into packed red blood cells units, and their distribution was evaluated, step-by...

journal_title：Vox sanguinis

authors： Marraccini C,Merolle L,Berni P,Boito K,Tamagnini I,Kuhn E,Ragazzi M,Baricchi R,Pertinhez TA

更新日期：2017-11-01 00:00:00

abstract：:A new therapeutic plasma exchange device developed by Sarns Inc./3M was evaluated in plasmapheresis of 20 healthy volunteers and in a multicenter clinical study of therapeutic plasma exchange that included 49 patients. Safety and efficacy of plasma separation from whole blood were assessed for a module that contains D...

journal_title：Vox sanguinis

authors： Kurtz SR,Carey PM,McGill M,Pineda AA,Zaroulis CG,Case MT

更新日期：1987-01-01 00:00:00

abstract：:The authors have studied the incidence of hepatitis associated antigen (HAA) and the homologous antibody in sera of patients with rheumatoid arthritis on the basis of (1) arthritis sometimes associated with viral hepatitis, (2) the possible infectious etiology of rheumatoid arthritis, and (3) observation on the possib...

journal_title：Vox sanguinis

authors： Marcolongo R,Debolini A

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak ABO variants may escape tests using unlicensed sera. MATERIALS AND METHODS:Prior to transfusion, ABO grouping was performed using an automated system and in-house diluted sera, and manual and bedside test techniques. Genotyping and sequencing were performed using standard methods. RESUL...

journal_title：Vox sanguinis

authors： Pruss A,Heymann GA,Braun J,Kiesewetter HH,Salama A

更新日期：2006-04-01 00:00:00

abstract：:This study reports the adaptation of an electronic particle-counting method for the enumeration of T cell and B cell rosettes of human lymphocytes. This method and the conventional hemocytometer method were compared in parallel on seventeen T cell and seven B cell rosette enumerations in a blind study design. All data...

journal_title：Vox sanguinis

authors： Denny TN,Kinsley KM,Benson JW,Bull RW

更新日期：1979-01-01 00:00:00

abstract：:beta 2-Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions beta 2-microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the c...

journal_title：Vox sanguinis

authors： Bernier GM

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...

journal_title：Vox sanguinis

authors： Beckman N,Cardigan R,Wallington T,Williamson LM

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Parvovirus B19 (B19V) DNA seems to persist in the plasma of B19V-infected blood donors. The relevance of this for recipients of single-donor blood components is yet unclear. MATERIAL AND METHODS:We studied serial archive and follow-up samples from 75 B19V-infected blood donors to obtain more ...

journal_title：Vox sanguinis

authors： Juhl D,Görg S,Hennig H

更新日期：2014-10-01 00:00:00

abstract：:We investigated the effects of gravitational force and three different plastic formulations of the storage bags on the quality of stored platelets by measuring the changes in platelet-associated immunoglobulin G (IgG) and two antigenic markers of the third component of human complement (C3), C3d and C3c. Pooled platel...

journal_title：Vox sanguinis

authors： Szymanski IO,Odgren PR,Teno RA,Jacobson MS,Surgenor DM

更新日期：1989-01-01 00:00:00

abstract：:With regard to hemostasis and thrombosis, collagens are among the most important physiologic components of the extracellular matrix in their role as platelet activators. Differences in the rate of platelet activation markedly influence normal hemostasis and the pathological outcome of thrombosis. Thus, collagen recept...

journal_title：Vox sanguinis

authors： Kunicki TJ,Nugent DJ

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Refractoriness to platelet transfusion because of HLA antibodies can jeopardize the outcome of patients who require platelet support during surgery. As routine screening for HLA antibodies would pose a huge burden on presurgical work-ups, a stratification of patients according to the risk of having HLA antib...

journal_title：Vox sanguinis

authors： Sanz C,Ghita G,Franquet C,Martínez I,Pereira A

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Factor VIII (FVIII) levels are used as a quality marker of fresh-frozen plasma (FFP); however, other clotting factors are not routinely measured. METHODS:We assessed additional haemostatic parameters and the dynamics of coagulation using Thrombelastography (TEG) and a thrombin generation test (TGT). FFP was...

journal_title：Vox sanguinis

authors： Lawrie AS,Cardigan RA,Williamson LM,Machin SJ,Mackie IJ

更新日期：2008-05-01 00:00:00

abstract：:An IgM kappa cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)-treated RBC. It resembled anti-Me cold agglutinin in these serological findings. However, the activity of this agglutinin against RBC was markedly de...

journal_title：Vox sanguinis

authors： Kajii E,Ikemoto S

更新日期：1989-01-01 00:00:00

abstract：:Prolonged storage of red blood cells (RBCs) at 4 degrees C results in decreased intracellular ATP levels with diminished posttransfusion survival. Meryman described a preservative medium, exceptional in its capacity to increase these intracellular levels during the first weeks of storage and later in maintaining adequ...

journal_title：Vox sanguinis

authors： Mazor D,Dvilansky A,Meyerstein N

更新日期：1994-01-01 00:00:00

abstract：:Paraformaldehyde-fixed platelets from normal donors were used for detection of antibody to platelet by in vitro sensitization (indirect method) utilizing rabbit anti-human IgG heavy chain specific antibody-coated polyacrylamide gels (Immunobeads). The sensitized platelets formed rosettes with Immunobeads and the posit...

journal_title：Vox sanguinis

authors： Salmassi S,Yokoyama MM,Maples JA,Matsui Y

更新日期：1980-11-01 00:00:00

abstract：:An alternative to blood transfusion, based on oxygen-carrying solutions, has been sought for over a century. The present 'first-generation' haemoglobin-products were based on observations that crosslinking with, for example, glutaraldehyde, overcame subunit dissociation and renal toxicity. Experience with these soluti...

journal_title：Vox sanguinis

authors： Winslow RM

更新日期：2006-08-01 00:00:00

abstract：:The modulation of humoral immunity by complement and complement receptors is presented, as well as the importance of the X chromosome in immune response. Gene rearrangement and ontogeny of the immunoglobulin isotypes are discussed with regard to humoral immunodeficiency diseases. ...

journal_title：Vox sanguinis

authors： Wedgwood RJ,Ochs HD

更新日期：1986-01-01 00:00:00

abstract：:Marrow transplantation is increasing, hematopoietic stem cells are being obtained from a wider variety of donors, and the cells almost always undergo some processing steps. These activities, along with the hematologic complexities of marrow transplant patients, create many varied opportunities for blood centers. ...

journal_title：Vox sanguinis

authors： McCullough J

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The clinical significance of immune thrombocytopenia (ITP) is mainly reflected by bleeding and/or bleeding risks, which, in some cases, cannot be adequately controlled by standard therapy. Tranexamic acid (TA) is increasingly used in preventing and reducing bleeding in several medical settings...

journal_title：Vox sanguinis

authors： Mayer B,Salama A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The membrane transporter ABCB6 has recently been shown to carry the high-frequency red-blood-cell (RBC) antigen Lan. All the Lan- individuals genotyped so far have inherited two recessive null mutations in ABCB6. The finding of a family with the Lan- blood type occurring in two successive gener...

journal_title：Vox sanguinis

authors： Saison C,Helias V,Peyrard T,Merad L,Cartron JP,Arnaud L

更新日期：2013-02-01 00:00:00

abstract：:Sera obtained from 4 mothers of children with neonatal alloimmune thrombocytopenia contained a platelet-specific alloantibody, anti-Bra, which defined an antigen apparently different from all known platelet alloantigens. All 4 fathers were Bra positive, whereas all mothers were Bra negative. The minimal postnatal valu...

journal_title：Vox sanguinis

authors： Kiefel V,Santoso S,Katzmann B,Mueller-Eckhardt C

更新日期：1988-01-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：:The effect of gamma irradiation on HIV and plasma coagulation factors F VIII:C, F VIII:vWF and FIX was studied. Donor plasma was harvested from single donations, frozen and irradiated in the frozen state at target doses from 0 to 40 kGy (0-4 mRad). HIV was inoculated into human plasma and irradiated in a similar manne...

journal_title：Vox sanguinis

authors： Kitchen AD,Mann GF,Harrison JF,Zuckerman AJ

更新日期：1989-01-01 00:00:00

abstract：:Serum IgE was determined by radioimmunoassay in 28 subjects affected by homozygous beta thalassemia (14 males and 14 females, aged 3-19 years, mean age 7 +/- 5.6 years). They were given transfusions with packed red cells and chelant therapy. Blood samples were taken just before a transfusion (basal value) and at 10-da...

journal_title：Vox sanguinis

authors： La Rosa M,Pavone L,Musumeci S,Mollica F,Ronchetti R

更新日期：1983-01-01 00:00:00

abstract：:A new granulocyte collection method employing discontinuous flow centrifugation and low donor dose of hydroxyethyl starch (HES) is presented. Following the procedure, the increase in serum polysaccharide concentration was 100 mg/dl, about 20% of that seen after standard discontinuous flow leukapheresis. The average ef...

journal_title：Vox sanguinis

authors： Szymanski IO

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ross River virus (RRV) is an enveloped, RNA alphavirus in the same antigenic group as chikungunya virus. Australia records an annual average of 5000 laboratory-confirmed RRV infections. While RRV is currently geographically restricted to the Western Pacific, the capacity of arboviruses for rap...

journal_title：Vox sanguinis

authors： Seed CR,Hoad VC,Faddy HM,Kiely P,Keller AJ,Pink J

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The ABO blood group system is the most important blood group system in transfusion medicine. In addition to the major A, B and O alleles, many rare alleles have been defined. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and analysis by PCR sequence specific pri...

journal_title：Vox sanguinis

authors： Chen YJ,Chen PS,Liu HM,Lyou JY,Hu HY,Lin JS,Tzeng CH

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Bleeding is increasingly considered an important end point in clinical platelet transfusion studies. Accurate recording and adjudication into well-defined bleeding grades, however, remains a major challenge. METHODS:We developed a computer algorithm for automatic adjudication. The algorithm's results were...

journal_title：Vox sanguinis

authors： Middelburg RA,Ypma PF,van der Meer PF,van Wordragen-Vlaswinkel RJ,Eissen O,Kerkhoffs JL

更新日期：2013-08-01 00:00:00