Abstract:
:Intra-operative blood cell salvage (IOCS) is mainly avoided in onco surgery due to the suspicion that it could increase metastasis' risk. We simulated IOCS followed by leucodepletion: HCT116 (human colorectal cancer) cells were inoculated into packed red blood cells units, and their distribution was evaluated, step-by-step, by flow cytometry and immunohistochemistry. Most of HCT116 cells were lost during washing, and almost completely removed after filtration. IOCS plus leucodepletion could be of great advantage for oncological patients, where allogenic blood transfusion could influence tumour progression.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Marraccini C,Merolle L,Berni P,Boito K,Tamagnini I,Kuhn E,Ragazzi M,Baricchi R,Pertinhez TAdoi
10.1111/vox.12565subject
Has Abstractpub_date
2017-11-01 00:00:00pages
803-805issue
8eissn
0042-9007issn
1423-0410journal_volume
112pub_type
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