Abstract:
:Alpha1-Acid glycoprotein (orosomucoid) was prepared from a byproduct of the ethanol plasma fractionation by means of ion-exchange procedures. Immunoelectrophoresis suggested a high degree of purity; the purified protein contained 13.5% sialic acid and 17.8% hexose. The alpha1-acid glycoprotein was modified by removal of sialic acid with neuraminidase (EC 3.2.1.18) followed by iodination with 131I. The purpose of the preparation, its potential use as a pharmacon for liver function studies in nuclear medicine is the subject of further study.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
van Rijk PP,Heinsius HL,van den Hamer CJdoi
10.1111/j.1423-0410.1976.tb02846.xsubject
Has Abstractpub_date
1976-01-01 00:00:00pages
412-9issue
6eissn
0042-9007issn
1423-0410journal_volume
30pub_type
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