Molecular basis of red cell protein antigen deficiencies.

abstract：:The polymorphism of the second component of human complement was studied by means of isoelectric focusing in polyacrylamide gels with subsequent complement-dependent lysis of sensitized sheep erythrocytes in an agarose overlay containing C2-deficient or normal human serum. In a material of 289 unrelated individuals th...

journal_title：Vox sanguinis

authors： Dewald G,Rittner C

更新日期：1979-01-01 00:00:00

abstract：:Hepatitis E virus (HEV)-positive plasma donations, identified by a plasma mini-pool screening approach, were analysed using serological methods for the presence of anti-HEV IgM and IgG. Avidity testing was performed on the IgG-reactive donations. Anti-HEV IgG with high avidity was observed in two donors together with ...

journal_title：Vox sanguinis

authors： Baylis SA,Crossan C,Corman VM,Blümel J,Scobie L,Dalton HR

更新日期：2015-11-01 00:00:00

abstract：:A family is presented, in which the mother developed strong neutrophil granulocyte-specific antibodies with the specificity anti-NA. The first and third children, both NA1-positive, suffered from severe transient neonatal neutropenia, but the second child, NA1-negative, did not. Anti-NA1 antibodies were detectable in ...

journal_title：Vox sanguinis

authors： Verheugt FW,van Noord-Bokhorst JC,von dem Borne AE,Engelfriet CP

更新日期：1979-01-01 00:00:00

abstract：:The decline in the incidence of TAH from 1985-1990 was considerable and based on a variety of interventions that led to increasingly intensive scrutiny of potential donors. The decline in incidence observed since 1990, and particularly since 1992, has been truly extraordinary and based principally on the introduction ...

journal_title：Vox sanguinis

authors： Alter HJ

更新日期：1994-01-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：:The presence of the glycoproteins haptoglobin and hemopexin in human plasma albumin (HPA) solutions were demonstrated to be responsible for the formation of polymers and aggregates during heat treatment for 10 h at 60 degrees C. Apart from haptoglobin and hemopexin three other contaminating proteins were identified as...

journal_title：Vox sanguinis

authors： Jensen LB,Dam J,Teisner B

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, Héma-Québec is considering the possibility of allowing men who have sex with men (MSM) to donate plasma for fractionation combined with a mandatory quarantine period. This study aims to assess the acceptability and operational feasibility of the programme in the targeted population....

journal_title：Vox sanguinis

authors： Caruso J,Germain M,Godin G,Myhal G,Pronovost F,Morin M,Otis J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion based on the Thrombelastograph (TEG) results reduces transfusion requirements in cardiac surgery and in liver transplantation. Taking the pivotal role of thrombin generation in the coagulation process into consideration, the clinical utility of the TEG may, in part, depend on its r...

journal_title：Vox sanguinis

authors： Johansson PI,Svendsen MS,Salado J,Bochsen L,Kristensen AT

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The ultimate goal was to generate an industrial-scale process suitable to produce a high-yield, safe and stable immunoglobulin G (IgG) preparation for intravenous administration, which is ready to use for customer convenience. This new liquid 10% IgG preparation (IGIV 10%) was compared to Gamm...

journal_title：Vox sanguinis

authors： Teschner W,Butterweck HA,Auer W,Muchitsch EM,Weber A,Liu SL,Wah PS,Schwarz HP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is concern regarding the lack of prevention of unnecessary transfusion of RhD negative red cells and unnecessary administration of Rh immunoglobulin (RhIG) to pregnant women. In this study, performance of ID RHD XT, a genotyping assay for identification of six RHD allelic variants and hu...

journal_title：Vox sanguinis

authors： Londero D,Monge J,Hellberg A

更新日期：2020-04-01 00:00:00

abstract：:Baboon red cells were treated to reduce oxygen affinity by an osmotic-pulse procedure using dimethyl-sulfoxide. Inositol hexaphosphate (IHP) alone or IHP and adenosine triphosphate (ATP) were incorporated into the red cells in the presence of polyethylene glycol (PEG). The procedure produced variable increases in the ...

journal_title：Vox sanguinis

authors： Franco RS,Weiner M,Wagner K,Martelo OJ,Ragno G,Pivacek LE,Valeri CR

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

journal_title：Vox sanguinis

authors： Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:HPA-1a antibodies account for 70-80% of cases of fetal-neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians. However, numerous workshops have demonstrated variability in their detection. We recently showed that exposure of αIIbβ3 to ethylene diamine tetraacetic acid (EDTA) affected bindi...

journal_title：Vox sanguinis

authors： Allen DL,Metcalfe P,Kaplan C,Kekomaki R,de Haas M,Yusuf R,Ouwehand WH

更新日期：2013-08-01 00:00:00

abstract：:Platelet antibodies were looked for in 47 patients with autoimmune thrombocytopenia using a modification of the enzyme-linked assay previously described. Surface-bound antibodies measured as increased platelet-associated IgG were found in 32 (68%) of the patients. After incubation in test sera, the platelet-associated...

journal_title：Vox sanguinis

authors： Hegde UM,Bowes A,Powell DK,Joyner MV

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:The Mirasol Pathogen Reduction Technology System (PRT) for Plasma (CaridianBCT) is based on a riboflavin and UV light treatment process resulting in pathogen inactivation due to irreversible, photochemically induced damage of nucleic acids. This study evaluated the in vitro protein quality of plasma products...

journal_title：Vox sanguinis

authors： Bihm DJ,Ettinger A,Buytaert-Hoefen KA,Hendrix BK,Maldonado-Codina G,Rock G,Giclas PC,Goodrich RP

更新日期：2010-02-01 00:00:00

abstract：:Isoagglutinins were investigated following ABO-incompatible bone marrow transplantation. In major incompatibility anti-A tends to require more time to disappear than anti-B. Correspondingly, A erythrocytes require more time to become demonstrable. There is no such difference in major plus minor incompatibility. In min...

journal_title：Vox sanguinis

authors： Wernet D,Mayer G

更新日期：1992-01-01 00:00:00

abstract：:In this prospective study, 26 consecutive patients being treated for haematological malignancies receiving standard (i.e. non-leucocyte-depleted) blood components were observed for the development of refractoriness to platelet transfusions. One hundred and sixteen of the 266 (44%) platelet transfusions failed to produ...

journal_title：Vox sanguinis

authors： Doughty HA,Murphy MF,Metcalfe P,Rohatiner AZ,Lister TA,Waters AH

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:Positive direct antiglobulin tests (DAT) occur occasionally, without obvious cause, among normal blood donors. This is sometimes associated with a false-positive serologic test for syphilis. Positive DATs due to antiphospholipid antibodies (APAbs) are well documented in the antiphospholipid syndrome with sys...

journal_title：Vox sanguinis

authors： Win N,Islam SI,Peterkin MA,Walker ID

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Necrotizing enterocolitis (NEC) is a common and often severe gastrointestinal emergency in newborn infants. While usually affecting (very) premature infants, an association between NEC and haemolytic disease of the foetus and newborn (HDFN) has been suggested. HDFN may be an additional risk fa...

journal_title：Vox sanguinis

authors： Ree IMC,de Grauw AM,Bekker V,de Haas M,Te Pas AB,Oepkes D,Middeldorp AJM,Lopriore E

更新日期：2020-02-01 00:00:00

abstract：:Recently, we have shown that thiopyrylium has robust inactivation capabilities against a broad spectrum of pathogens in the human red blood cell (RBC) suspensions while retaining key RBC in vitro properties. The 24-h recovery and survival of canine red cells were measured upon autologus reinfusion of control and photo...

journal_title：Vox sanguinis

authors： Skripchenko A,Balch A,Mackin A,Wagner SJ

更新日期：2007-02-01 00:00:00

abstract：:Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...

journal_title：Vox sanguinis

authors： Yoshida H,Ito K,Emi N,Kanzaki H,Matsuura S

更新日期：1984-01-01 00:00:00

abstract：:2,140 pregnant Sudanese women attending the antenatal clinic in Omdurman Maternity Hospital during the period November 1975 to December 1976 had ABO and Rh typing performed. Their sera were also screened by a modified papain enzyme technique for the presence of atypical antibodies. The rate of Rhesus immunization, the...

journal_title：Vox sanguinis

authors： Abu-Sin AY,Ayoub M,Abdelrazig H

更新日期：1978-01-01 00:00:00

abstract：:The number of cord blood transplants has been increasing very quickly with more than 250 cases reported to Eurocord Registry and more than 500 patients transplanted via the New York Cord Blood Bank. Cord blood transplants have been performed either with related or unrelated cord blood. Several cord blood banks establi...

journal_title：Vox sanguinis

authors： Gluckman E,Rocha V,Chastang C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In order to reduce the potential for transmission of hepatitis C virus (HCV) from an RNA-positive, anti-HCV-negative blood donation, the National Blood Service (NBS) introduced nucleic acid amplification technology (NAT) testing for HCV in England and Wales. The objective of this study was to ...

journal_title：Vox sanguinis

authors： Grant PR,Sims CM,Krieg-Schneider F,Love EM,Eglin R,Tedder RS

更新日期：2002-05-01 00:00:00

abstract：:BS II lectin, a second hemagglutinin isolated from Bandeiraea simplicifolia seeds, agglutinated the red cells from 11 patients manifesting the 'acquired B' antigen phenomenon. The results of serological studies indicate that this lectin has specificity for the type III polyagglutinable receptors rather than for the 'B...

journal_title：Vox sanguinis

authors： Judd WJ,Beck ML,Hicklin BL,Iyer PN,Goldstein IJ

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Capillary samples can provide blood for cell counts in haematologic patients and blood donors. However, some accept only values from venous blood. This study compares capillary and venous blood counts to verify the hypothesis that they are equivalent. MATERIALS AND METHODS:We analysed 463 cap...

journal_title：Vox sanguinis

authors： Schalk E,Heim MU,Koenigsmann M,Jentsch-Ullrich K

更新日期：2007-11-01 00:00:00

abstract：:Routine screening of blood donations for anti-HIV commenced in the UK during October 1985 and by the end of February 1987 approximately 3.7 million donations had been tested. Seventy-two were confirmed anti-HIV positive, i.e. 0.002%. Of the anti-HIV-positive donors interviewed to date, the majority are young homosexua...

journal_title：Vox sanguinis

authors： Gunson HH,Rawlinson VI

更新日期：1988-01-01 00:00:00

abstract：:Serum from a pregnant woman with the May-Hegglin anomaly contained a platelet-specific antibody. The serum reacted in the platelet indirect immunofluorescence test (PIIFT) with 97.6% of random donor platelets and those of the father but not with the mother's own platelets. This antibody induced a moderate thrombocytop...

journal_title：Vox sanguinis

authors： Bettaieb A,Fromont P,Rodet M,Godeau B,Duedari N,Bierling P

更新日期：1991-01-01 00:00:00

abstract：:A major drawback in the use of platelet transfusions is the development of platelet refractoriness that is usually caused by alloimmunization provoked by leukocytes present in the blood products. We evaluated the development of alloimmunization both by serological demonstration of HLA antibodies and by clinical demons...

journal_title：Vox sanguinis

authors： Saarinen UM,Koskimies S,Myllylä G

更新日期：1993-01-01 00:00:00