Current status of oxygen carriers ('blood substitutes'): 2006.

abstract：BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

journal_title：Vox sanguinis

authors： Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The membrane transporter ABCB6 has recently been shown to carry the high-frequency red-blood-cell (RBC) antigen Lan. All the Lan- individuals genotyped so far have inherited two recessive null mutations in ABCB6. The finding of a family with the Lan- blood type occurring in two successive gener...

journal_title：Vox sanguinis

authors： Saison C,Helias V,Peyrard T,Merad L,Cartron JP,Arnaud L

更新日期：2013-02-01 00:00:00

abstract：:beta 2-Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions beta 2-microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the c...

journal_title：Vox sanguinis

authors： Bernier GM

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：:One of the most controversial policies in blood transfusion worldwide is the permanent deferral from donating blood of men with sexual contacts to other men (MSM). This policy was implemented for safety reasons as sex between men is known to be a high risk factor for acquiring severe infectious diseases transmissible ...

journal_title：Vox sanguinis

authors： Offergeld R,Kamp C,Heiden M,Norda R,Behr-Gross ME

更新日期：2014-11-01 00:00:00

abstract：:Quality management is an ongoing development resulting in consistency products and services and ever increasing customer satisfaction. The ultimum is Total Quality Management. Quality systems and quality management in transfusion medicine have gained considerable attention since the outbreak of the AIDS epidemic. Wher...

journal_title：Vox sanguinis

authors： Smit-Sibinga CT

更新日期：2000-01-01 00:00:00

abstract：:An IgM kappa cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)-treated RBC. It resembled anti-Me cold agglutinin in these serological findings. However, the activity of this agglutinin against RBC was markedly de...

journal_title：Vox sanguinis

authors： Kajii E,Ikemoto S

更新日期：1989-01-01 00:00:00

abstract：:Two preparations of fresh frozen plasma were studied. The plasma from CPDA-1 whole blood units was either frozen within 6 h (FFP-I) or 18-20 h (FFP-II) of phlebotomy. Average activity for factor VIII for FFP-I (n = 6) and FFP-II (n = 19) was 102% and 55%, respectively (p less than 0.01). Average activity for factor V ...

journal_title：Vox sanguinis

authors： Kakaiya RM,Morse EE,Panek S

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：:We here report 2 patients who have acquired two consecutive episodes each of acute hepatitis, within 6 months after blood transfusion. The clinical and biochemical course was typical of recurrent acute viral hepatitis, and the patients recovered completely after each episode. The first infection was probably caused by...

journal_title：Vox sanguinis

authors： Ben-Dov I,Fainaru M

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Since July 1 1999, four laboratories in the Netherlands have been routinely screening plasma minipools for the release of labile blood components utilizing hepatitis C virus nucleic acid amplification technology (HCV NAT). This report describes the performance evaluation of the HCV NAT method ...

journal_title：Vox sanguinis

authors： Cuijpers HT,Molijn MH,Bos HJ,Peeters AP,van der Poel CL,Lelie PN

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous-flow and intermittent-flow blood cell separators (CFCS and IFCS) are both used to collect stem cells from the blood to rescue patients undergoing myeloablative treatment for cancer. MATERIALS AND METHODS:We designed a study to compare the collection efficiency of the two systems. T...

journal_title：Vox sanguinis

authors： Beretta F,van den Bosch S,Castelli D,Cavalli F,Ghielmini M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to assess potentially relevant clinical characteristics which influence the decision to transfuse red cells in critically ill patients with low haemoglobin concentrations (6.0-10.0 g/dl). MATERIALS AND METHODS:This was a retrospective observational cohort study of pa...

journal_title：Vox sanguinis

authors： Kranenburg FJ,le Cessie S,Caram-Deelder C,van der Bom JG,Arbous MS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The rationale for using topical platelet gel therapy is to provide the healing tissues with concentrated platelet-derived factors. Several systems are available to prepare platelet-rich plasma (PRP) and from these, the platelet gel. These systems produce two- to six-fold platelet and growth factor-enriched c...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Guaschino R,Borzini P

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Partially replacing plasma with additive solutions in platelet (PLT) concentrates (PCs) may help to reduce transfusion reactions. Constituents of PLT additive solutions (PASs) have been revealed to affect the quality of PCs. Previous studies involved pairwise comparison of identical PLTs with ...

journal_title：Vox sanguinis

authors： Nogawa M,Naito Y,Chatani M,Onodera H,Shiba M,Okazaki H,Matsuzaki K,Satake M,Nakajima K,Tadokoro K

更新日期：2013-11-01 00:00:00

abstract：:This report describes the recovery of highly purified immune-serum globulin (ISG) from the 42% ethanol precipitate fraction (42% P) generated during the first step of albumin purification. The method consists of three purification steps: (1) reprecipitation of the 42% P at 20% ethanol, pH 7.2; (2) solubilization of IS...

journal_title：Vox sanguinis

authors： Hao YL,Wickerhauser M

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Host- or donor-derived alloimmune thrombocytopenia can develop after non-myeloablative allogeneic haematopoietic stem cell transplantation (HSCT). We report the first case of host-derived HPA-1a antibodies. CASE REPORT:A 52-year-old male patient received HSCT from his human leucocyte antigen ...

journal_title：Vox sanguinis

authors： Macher S,Schallmoser K,Staber PB,Neumeister P,Posch U,Lanzer G,Panzer S

更新日期：2005-11-01 00:00:00

abstract：:Hepatitis E is considered an emerging disease that may be a threat in both developing and industrialized countries all over the world. The risk of chronic hepatitis E virus infection is higher among immunocompromised patients. This study aimed to assess the status of hepatitis E infection in patients with transfusion-...

journal_title：Vox sanguinis

authors： Klonizakis P,Gioula G,Exindari M,Apostolou C,Kotsiafti A,Vlachaki E

更新日期：2017-10-01 00:00:00

abstract：:In recent years the development of recombinant DNA and sequencing techniques has led to a greatly increased understanding of the genetic complexity, structure and function of the human major histocompatibility complex. This system may be subdivided into the "classical' HLA (human leukocyte antigen) class I and II tran...

journal_title：Vox sanguinis

authors： Howell WM,Navarrete C

更新日期：1996-01-01 00:00:00

abstract：:The formation of mono(ethylhexyl)phthalate (MEHP) from di(ethylhexyl)phthalate in human plasma stored in bags of polyvinylchloride has been studied. Substantial amounts were formed and in ten bags from 4 to 56microgram/ml were found. After 2 weeks at room temperature the concentration of MEHP had increased to values b...

journal_title：Vox sanguinis

authors： Vessman J,Rietz G

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:IgG subclasses of anti-D seem to play some role in hemolytic disease of the newborn, but there has been disagreement as to its exact nature. The aim of our study was to evaluate a new technique for IgG subclassing of anti-D and to compare it to an established test. MATERIALS AND METHODS:In 31...

journal_title：Vox sanguinis

authors： Palfi M,Hildén JO

更新日期：1997-01-01 00:00:00

abstract：:To obtain red cell populations of increasing mean age erythropoiesis was arrested through continuous actinomycin treatment or maintained transfusion polycythemia in mice and rats respectively. The parameters studied included cell indices, enzyme activities and rheological characteristics. Further, the life-span of age...

journal_title：Vox sanguinis

authors： Ganzoni AM,Barras JP,Marti HR

更新日期：1976-01-01 00:00:00

abstract：:The polymorphism of the second component of human complement was studied by means of isoelectric focusing in polyacrylamide gels with subsequent complement-dependent lysis of sensitized sheep erythrocytes in an agarose overlay containing C2-deficient or normal human serum. In a material of 289 unrelated individuals th...

journal_title：Vox sanguinis

authors： Dewald G,Rittner C

更新日期：1979-01-01 00:00:00

abstract：:Employing standardized IgG-coated 51Cr-labelled human red blood cells (RBC), variation in rosette formation among monolayers obtained from 10 healthy donors was defined, as well as variation among 24 sequential monolayers obtained from one healthy donor and 8 sequential monolayers from a second healthy donor over a 4-...

journal_title：Vox sanguinis

authors： Munn LR,Chaplin H Jr

更新日期：1977-09-01 00:00:00

abstract：:Manual plasmapheresis is done worldwide on both paid donors, and to a much smaller extent on volunteer donors in order to generate source plasma to be fractionated into albumin, clotting factor concentrates, and gamma globulin. Automated technology has now been developed utilizing both centrifugal, and membrane separa...

journal_title：Vox sanguinis

authors： Gilcher RO

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The amino acid substitutions caused by ABO gene variants are usually predicted to impact the glycosyltransferase function. Here, the effect of an amino acid substitution in the vicinity of the catalytic active region of the B-glycosyltransferase was explored in vitro and in silico study, which is important f...

journal_title：Vox sanguinis

authors： Ying Y,Hong X,Xu X,Zhang J,He J,Zhu F,Xie X

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Miltenberger subtype III (Mi.III, GP.Mur) is one of the most important red cell phenotypes in the fields of transfusion in South-East Asia. GP.Mur is believed to evolve from homologous gene recombination events between glycophorin A (GYPA) and glycophorin B (GYPB). GYP.Mur differs from GYPB in...

journal_title：Vox sanguinis

authors： Hsu K,Yao CC,Lin YC,Chang CL,Lee TY

更新日期：2015-05-01 00:00:00

abstract：:Prolonged storage of red blood cells (RBCs) at 4 degrees C results in decreased intracellular ATP levels with diminished posttransfusion survival. Meryman described a preservative medium, exceptional in its capacity to increase these intracellular levels during the first weeks of storage and later in maintaining adequ...

journal_title：Vox sanguinis

authors： Mazor D,Dvilansky A,Meyerstein N

更新日期：1994-01-01 00:00:00

abstract：:If leukocyte- and platelet-poor red cells have been processed and stored in closed bags, their delivery, especially on holidays, will be easy. The modified warm-centrifuge method was applied to a quadruple bag prepared for such purpose. Red cells were processed in the first bag by the centrifugation of whole blood. Th...

journal_title：Vox sanguinis

authors： Shimizu T,Ishikawa Y,Tsurumi H,Hibi S,Takakura R,Morishima Y,Hasegawa I,Goto S

更新日期：1986-01-01 00:00:00