The dynamics of clot formation in fresh-frozen plasma.

abstract：OBJECTIVES:Baxter's methylene blue (MB) photoinactivation of fresh frozen plasma (FFP) is a method that effectively removes any intracellular potentially infectious agent, such as prions, by filtration combined with an improved photochemical virus inactivation on a single unit of FFP. The purpose of this study was to d...

journal_title：Vox sanguinis

authors： Simonsen AC,Sørensen H

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Partially replacing plasma with additive solutions in platelet (PLT) concentrates (PCs) may help to reduce transfusion reactions. Constituents of PLT additive solutions (PASs) have been revealed to affect the quality of PCs. Previous studies involved pairwise comparison of identical PLTs with ...

journal_title：Vox sanguinis

authors： Nogawa M,Naito Y,Chatani M,Onodera H,Shiba M,Okazaki H,Matsuzaki K,Satake M,Nakajima K,Tadokoro K

更新日期：2013-11-01 00:00:00

abstract：:The effect on cryoprecipitate factor VIII recovery of three imortant variables has been investigated. The design of the study was such as to eliminate, for the purpose of internal comparisons, spurious effects such as those due to the variation in factor VIII levels in donor plasma. The choice of anticoagulant was sho...

journal_title：Vox sanguinis

authors： Wensley RT,Snape TJ

更新日期：1980-01-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：:Radioimmunoassays were prepared using two anti-A and one anti-B reagents. The specificity of the procedures was assessed with 13 artificial antigens. The amounts of A and B natural antigens in saliva of ABH secretors of known Lewis phenotype were measured with these assays. The results confirmed that the average amoun...

journal_title：Vox sanguinis

authors： Le Pendu J,Lemieux RU,Dalix AM,Lambert F,Oriol R

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pr1,2,3, PrM, Sa and Sia-l1, -b1, -lb1 are sialic acid (NeuNAc)-dependent antigens recognized by human cold agglutinins. Pr and Sa antigens are the O-glycans of glycophorins containing alpha 2,3NeuNAc (to galactose) and/or alpha 2,6NeuNAc (to galactosamine). The antigens of the Sia-l1, -b1, -l...

journal_title：Vox sanguinis

authors： Roelcke D,Hack H,Kreft H,Gross HJ

更新日期：1998-01-01 00:00:00

abstract：:In this prospective study, 26 consecutive patients being treated for haematological malignancies receiving standard (i.e. non-leucocyte-depleted) blood components were observed for the development of refractoriness to platelet transfusions. One hundred and sixteen of the 266 (44%) platelet transfusions failed to produ...

journal_title：Vox sanguinis

authors： Doughty HA,Murphy MF,Metcalfe P,Rohatiner AZ,Lister TA,Waters AH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Neonatal alloimmune thrombocytopenia is usually attributable to HPA-la antibodies. We report a case of parental platelet antigen incompatibility associated with a severe neonatal thrombocytopenia secondary to alloimmunization to HPA-3a. MATERIALS AND METHODS:Platelet antibodies were detected ...

journal_title：Vox sanguinis

authors： Boehlen F,Kaplan C,de Moerloose P

更新日期：1998-01-01 00:00:00

abstract：:The second example of anti-F1 cold agglutinins recognizing a developmentally regulated antigen like I is described. The antibody occurred transiently and simultaneously together with an anti-I cold agglutinin. Although anti-F1 and anti-I specificities are entirely different, the data on the biochemistry of F1 and I an...

journal_title：Vox sanguinis

authors： Roelcke D,Weber MT

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We identified some fatal cases where massively bleeding patients received inadequate transfusion therapy. The aim of this study was to review and evaluate the transfusion practice in acutely multitransfused patients. MATERIALS AND METHODS:Patients receiving > 10 units of red blood cells (RBC)...

journal_title：Vox sanguinis

authors： Johansson PI,Hansen MB,Sørensen H

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Refractoriness to platelet transfusion because of HLA antibodies can jeopardize the outcome of patients who require platelet support during surgery. As routine screening for HLA antibodies would pose a huge burden on presurgical work-ups, a stratification of patients according to the risk of having HLA antib...

journal_title：Vox sanguinis

authors： Sanz C,Ghita G,Franquet C,Martínez I,Pereira A

更新日期：2010-10-01 00:00:00

abstract：:A family is reported in which the parents' mating is of the 'double back-cross' type with respect to the Sw, Lu and Se genes. The inheritance of these genes in the children shows, with reference to a possible linkage between Sw and the two other loci, four non-recombinants and three recombinants (or vice versa). The i...

journal_title：Vox sanguinis

authors： Metaxas MN,Metaxas-Buehler M

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, Héma-Québec is considering the possibility of allowing men who have sex with men (MSM) to donate plasma for fractionation combined with a mandatory quarantine period. This study aims to assess the acceptability and operational feasibility of the programme in the targeted population....

journal_title：Vox sanguinis

authors： Caruso J,Germain M,Godin G,Myhal G,Pronovost F,Morin M,Otis J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

journal_title：Vox sanguinis

authors： Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

更新日期：2020-04-01 00:00:00

abstract：:Two batches of heat-treated factor VIII concentrate were found to contain anti-HIV-positive plasma donations. The batches were dry-heat-treated at 68 degrees C for 2 and 24 h, respectively. No HIV seroconversions occurred in 13 susceptible haemophiliacs receiving a total of 540 bottles of these factor VIII preparation...

journal_title：Vox sanguinis

authors： Cuthbert RJ,Ludlam CA,Brookes E,McClelland DB

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Host- or donor-derived alloimmune thrombocytopenia can develop after non-myeloablative allogeneic haematopoietic stem cell transplantation (HSCT). We report the first case of host-derived HPA-1a antibodies. CASE REPORT:A 52-year-old male patient received HSCT from his human leucocyte antigen ...

journal_title：Vox sanguinis

authors： Macher S,Schallmoser K,Staber PB,Neumeister P,Posch U,Lanzer G,Panzer S

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The non-paired two-arm study compared the in vitro storage characteristics of platelets suspended as concentrates in either 100% plasma or a mixture of additive solution (SSP+™, MacoPharma, Mouveaux, France) and autologous plasma in a 70:30 ratio over a 14-day storage period. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Saunders C,Rowe G,Wilkins K,Holme S,Collins P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A multicentre trial was set up to evaluate the performance of a new leucodepletion protocol. MATERIALS AND METHODS:Filtration at high haematocrit was started during collection of red blood cell (RBC) products by apheresis with Trima. SAG-M was added after filtration through the filter. Haemat...

journal_title：Vox sanguinis

authors： Soli M,Blanco L,Riggert J,Martínez-Clavel A,Lucas C,Lunghi M,Belloni M,Wolf C,van Waeg G,Antoon M

更新日期：2001-01-01 00:00:00

abstract：:Two preparations of fresh frozen plasma were studied. The plasma from CPDA-1 whole blood units was either frozen within 6 h (FFP-I) or 18-20 h (FFP-II) of phlebotomy. Average activity for factor VIII for FFP-I (n = 6) and FFP-II (n = 19) was 102% and 55%, respectively (p less than 0.01). Average activity for factor V ...

journal_title：Vox sanguinis

authors： Kakaiya RM,Morse EE,Panek S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. MATERIAL AND METHODS:To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets conce...

journal_title：Vox sanguinis

authors： Brito F,Cordey S,Delwart E,Deng X,Tirefort D,Lemoine-Chaduc C,Zdobnov E,Lecompte T,Kaiser L,Waldvogel-Abramowski S,Preynat-Seauve O

更新日期：2018-07-18 00:00:00

abstract：:Platelet concentrates were prepared in plastic packs of polyvinyl chloride with tri(2-ethylhexyl) trimellitate as plasticizer. They were stored, with gentle shaking, at room temperature for periods up to 7 days before labelling with isotope and reinfusing. In vivo survival studies, platelet counts, pH and electron mic...

journal_title：Vox sanguinis

authors： Archer GT,Grimsley PG,Jindra J,Robson JE,Ribeiro A

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Whole blood is stored at room temperature (RT) until processing into components. After separation and filtration, the RCC has to be cooled from RT to +2 - 6°C. Different start times of the cooling process and different cooling rates can be encountered in daily routine. The effect of these parameters of the i...

journal_title：Vox sanguinis

authors： Bontekoe IJ,van der Meer PF,de Korte D

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:We have developed and optimised a new flow-cytometric method for the measurement of the Fc function of intravenous immunoglobulin (IVIg) preparations, which is important in predicting the effector function of immunoglobulin (Ig) in such preparations. MATERIALS AND METHODS:Ig was bound to a monocytic cell li...

journal_title：Vox sanguinis

authors： Ramasamy I,Tran E,Charnock A,Farrugia A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of the study was to replace the 1(st) World Health Organization International Standard for parvovirus B19 DNA for nucleic acid amplification technique (NAT)-based assays (code 99/800). Two lyophilized preparations (coded 99/800 and 99/802) had been evaluated in the original collaborati...

journal_title：Vox sanguinis

authors： Baylis SA,Chudy M,Blümel J,Pisani G,Candotti D,José M,Heath AB

更新日期：2010-04-01 00:00:00

abstract：:Metabolic properties of standard gamma globulin (St-GG) and of several gamma globulin (GG) preparations for intravenous use were analyzed in radioactive tracer studies. The in vivo behaviour of St-GG was investigated in 16 probands and found to be comparable to that of normal IgG. The kinetics of the resorption of St-...

journal_title：Vox sanguinis

authors： Morell A,Schürch B,Ryser D,Hofer F,Skvaril F,Barandun S

更新日期：1980-01-01 00:00:00

abstract：:Quality management is an ongoing development resulting in consistency products and services and ever increasing customer satisfaction. The ultimum is Total Quality Management. Quality systems and quality management in transfusion medicine have gained considerable attention since the outbreak of the AIDS epidemic. Wher...

journal_title：Vox sanguinis

authors： Smit-Sibinga CT

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The low-prevalence Rh antigen, JAL, was named after the index case, Mr. J. Allen. Based on reactivity of seven multi-specific sera with his RBCs, it was apparent that they express at least one additional low-prevalence antigen. The purpose of this study was to investigate the other low-prevalence antigen(s) ...

journal_title：Vox sanguinis

authors： Hue-Roye K,Reid ME,Westhoff CM,Lomas-Francis C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Analysis of haemoglobin (Hb) dilution after bleeding is a simple, inexpensive and non-invasive method to estimate blood loss. Blood volume is estimated, taking sex, weight and height into account. The Hb concentration before and after blood loss is analysed and, from the difference, the blood ...

journal_title：Vox sanguinis

authors： Meunier A,Petersson A,Good L,Berlin G

更新日期：2008-08-01 00:00:00

abstract：:The first reported example of autoimmune hemolytic anemia due to an autoanti-Gerbich is described. The patient's red blood cells exhibited a strongly positive direct antiglobulin test with both IgG and complement antiglobulin reagents. The serum contained a potent antibody which produced agglutination of red blood cel...

journal_title：Vox sanguinis

authors： Reynolds MV,Vengelen-Tyler V,Morel PA

更新日期：1981-01-01 00:00:00

abstract：:The Gm allotype constitution of the autoantibody molecules and the serum Gm phenotypes were determined in 19 patients with autiommune hemolytic anemia of IgG type. The results showed that the known heterogeneity of the antierythrocyte autoantibodies in this disease concerns not only the immunoglobulin class and the is...

journal_title：Vox sanguinis

authors： Le Petit JC,Rivat L,François N,Ropartz C,Brizard CP

更新日期：1976-01-01 00:00:00