Severe thrombocytopenia due to host-derived anti-HPA-1a after non-myeloablative allogeneic haematopoietic stem cell transplantation for multiple myeloma: a case report.

abstract：BACKGROUND AND OBJECTIVES:Antibodies of unknown specificity (AUS) are frequently identified in the pre-transfusion testing. These antibodies can be insignificant or potentially cause post-transfusion haemolysis. Information about the prevalence of clinically relevant AUS is still lacking. Our aim was to predict the pot...

journal_title：Vox sanguinis

authors： de Albuquerque da Veiga Conrado MC,Cardoso RA,Dezan MR,Oliveira VB,Neto ADC,Ziza KC,Krieger JE,Pereira AC,Sabino EC,Rocha V,Mendrone-Júnior A,Dinardo CL

更新日期：2019-08-01 00:00:00

abstract：:A red cell IgM autoantibody with anti-e specificity was identified in the serum of a rhesus-negative (rr) patient presenting with haemolytic anaemia and a negative direct antiglobulin test. The autoantibody strongly agglutinated normal allogeneic rhesus-negative (rr) red cells in saline at 37 degrees C but had only we...

journal_title：Vox sanguinis

authors： Herron R,Clark M,Smith DS

更新日期：1987-01-01 00:00:00

abstract：:The modulation of humoral immunity by complement and complement receptors is presented, as well as the importance of the X chromosome in immune response. Gene rearrangement and ontogeny of the immunoglobulin isotypes are discussed with regard to humoral immunodeficiency diseases. ...

journal_title：Vox sanguinis

authors： Wedgwood RJ,Ochs HD

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The risk of transmitting hepatitis C (HCV) by transfusion of anti-HCV-negative screened blood was estimated for the blood donor population of Baden-Württemberg (southwestern Germany). METHODS:The data from the blood donors screened for anti-HCV and for HBsAg during 1990-1995 were analyzed. RESULTS:The preva...

journal_title：Vox sanguinis

authors： Koerner K,Cardoso M,Dengler T,Kerowgan M,Kubanek B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The para-Bombay phenotype (also known as H-deficient secretor) is characterized by a lack of ABH antigens on red cells, but ABH substances are found in saliva. Molecular genetic analysis was performed for five Chinese individuals serologically typed as para-Bombay. MATERIALS AND METHODS:ABO g...

journal_title：Vox sanguinis

authors： Yip SP,Chee KY,Chan PY,Chow EY,Wong HF

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Practices in end-of-life platelet transfusions in haematologic malignancies are variable. Our aim was to describe the platelet transfusion burden and parameters linked to this indication in such a setting and thereby contribute to defining optimal practices. MATERIALS AND METHODS:From July 20...

journal_title：Vox sanguinis

authors： Moracchini J,Seigeot A,Angelot-Delettre F,Vienot A,Aubry R,Daguindau É,Deconinck E,Frache S,Tiberghien P

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...

journal_title：Vox sanguinis

authors： Borzini P,Riva M,Nembri P,Rossi E,Pagliaro P,Vergani P,Greppi P,Tantardini P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak ABO variants may escape tests using unlicensed sera. MATERIALS AND METHODS:Prior to transfusion, ABO grouping was performed using an automated system and in-house diluted sera, and manual and bedside test techniques. Genotyping and sequencing were performed using standard methods. RESUL...

journal_title：Vox sanguinis

authors： Pruss A,Heymann GA,Braun J,Kiesewetter HH,Salama A

更新日期：2006-04-01 00:00:00

abstract：:A method is described for the production of mouse monoclonal antibodies to HBsAg. 4 clones produced antibodies directed at the a and one at the d determinant of HBsAg. These antibodies were conjugated to horse radish peroxidase and used in an Elisa for the detection of HBsAg in donated blood. Antibody C10 produced con...

journal_title：Vox sanguinis

authors： Els MC,Govender M,Marimuthu T,Bubb MO,Conradie JD

更新日期：1984-01-01 00:00:00

abstract：:Alloimmune neonatal thrombocytopenia (ANT) may cause intracranial haemorrhage in utero as well as at delivery. Recent management has concentrated on attempts to minimise fetal thrombocytopenia and prevent its complications. This report describes further experience with the use of repeated intravascular transfusions of...

journal_title：Vox sanguinis

authors： Murphy MF,Pullon HW,Metcalfe P,Chapman JF,Jenkins E,Waters AH,Nicolaides KH,Mibashan RS

更新日期：1990-01-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The International Haemovigilance Network collects aggregate data on complications of blood donation from member haemovigilance systems (HVS). We analysed the data collected in 2006-2016 in order to learn from it and consider future improvements. MATERIALS AND METHODS:National HVS entered annu...

journal_title：Vox sanguinis

authors： Wiersum-Osselton JC,Politis C,Richardson C,Goto N,Grouzi E,Marano G,Land KJ

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite improved methods for detecting bacterial contamination of blood products, bacterial sepsis remains a significant risk in blood transfusion. This study was undertaken to investigate whether adopting a different skin disinfection protocol could reduce the rate of bacterial contamination ...

journal_title：Vox sanguinis

authors： Lee CK,Ho PL,Chan NK,Mak A,Hong J,Lin CK

更新日期：2002-10-01 00:00:00

abstract：:The 2nd-generation anti-HCV test system was applied to a Saudi Arabian multi-ethnic donor population. When donors were stratified according to first-time donations versus repeat donations, the latter having been screened previously by a 1st-generation set of tests, it was found that in Saudi Arabian and Middle East na...

journal_title：Vox sanguinis

authors： Bernvil SS,Andrews VJ,Sasich F

更新日期：1994-01-01 00:00:00

abstract：:Anti-HBc is the most sensitive indicator of current or recent hepatitis B virus infection, hence its detection is valuable in laboratory diagnosis of the infection. Dane particles isolated from the plasma of a single chronic carrier and his autologous IgG labeled with 125I were utilized in a solid-phase sandwich radio...

journal_title：Vox sanguinis

authors： Vyas GN,Roberts IM

更新日期：1977-12-01 00:00:00

abstract：:Peripheral blood stem cell cryopreservation is associated with cell damage and decreased viability. We evaluated the impact of up to 10 years of cryopreservation (5% DMSO) on viability of CD34(+) cells utilizing graft samples of consecutive patients (2002-2012) with different malignancies who underwent stem cell colle...

journal_title：Vox sanguinis

authors： Abbruzzese L,Agostini F,Durante C,Toffola RT,Rupolo M,Rossi FM,Lleshi A,Zanolin S,Michieli M,Mazzucato M

更新日期：2013-07-01 00:00:00

abstract：:Low-dose immune tolerance protocols use doses of factor VIII of less than 50 IU/kg/day to induce immune tolerance. Such protocols are chosen for a variety of reasons including cost, patient acceptability and ease of administration. Early published reports of low-dose protocols appeared in 1981, described small numbers...

journal_title：Vox sanguinis

authors： Sultan Y

更新日期：1999-01-01 00:00:00

abstract：:Previously described methods of phenotyping red cells sensitised with IgG using the indirect antiglobulin test required the dissociation of the coating protein. Based on an entirely different principle, Fab fragments of anti-human IgG (Fab anti-IgG) were used to block the antiglobulin binding sites on cell-bound IgG m...

journal_title：Vox sanguinis

authors： Henry SM,Baird SJ,Woodfield DG

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Refractoriness to platelet transfusion because of HLA antibodies can jeopardize the outcome of patients who require platelet support during surgery. As routine screening for HLA antibodies would pose a huge burden on presurgical work-ups, a stratification of patients according to the risk of having HLA antib...

journal_title：Vox sanguinis

authors： Sanz C,Ghita G,Franquet C,Martínez I,Pereira A

更新日期：2010-10-01 00:00:00

abstract：:This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection again...

journal_title：Vox sanguinis

authors： Booth JR,Nuttall PA

更新日期：1978-01-01 00:00:00

abstract：:The interaction of temperature and pH in biological systems comprises two components. Temperature change may perturb the pH of solutions, and it may change the pKa of some ionizable groups that are involved in enzyme catalysis. The pH optima of single reactions and whole pathways are therefore temperature sensitive. T...

journal_title：Vox sanguinis

authors： Guppy M,Attwood PV,Hansen IA,Sabaratnam R,Frisina J,Whisson ME

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent studies suggest that transfusion of old red blood cell (RBC)s, mainly those close to the 42-day maximum shelf life (MSL), is associated with increased morbi-mortality. Although there is no formal proof supporting a causal relationship, the precautionary principle asks for corrective inte...

journal_title：Vox sanguinis

authors： Grasas A,Pereira A,Bosch MA,Ortiz P,Puig L

更新日期：2015-04-01 00:00:00

abstract：:The present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. It is a suitable technique for measurement of these parameters in small samples wh...

journal_title：Vox sanguinis

authors： Kaplan JE,Blumenstock FA,Saba TM

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Human monoclonal antibodies have been produced against various Rh antigens. We report here the production of another one against Rh C and the first such antibody against Rh CW. MATERIALS AND METHODS:Two heterohybridomas secreting IgG human monoclonal antibodies against Rh CW and Rh C (MS-353 ...

journal_title：Vox sanguinis

authors： Thorpe SJ,Boult CE,Thompson KM

更新日期：1997-01-01 00:00:00

abstract：:The number of cord blood transplants has been increasing very quickly with more than 250 cases reported to Eurocord Registry and more than 500 patients transplanted via the New York Cord Blood Bank. Cord blood transplants have been performed either with related or unrelated cord blood. Several cord blood banks establi...

journal_title：Vox sanguinis

authors： Gluckman E,Rocha V,Chastang C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The clinical significance of immune thrombocytopenia (ITP) is mainly reflected by bleeding and/or bleeding risks, which, in some cases, cannot be adequately controlled by standard therapy. Tranexamic acid (TA) is increasingly used in preventing and reducing bleeding in several medical settings...

journal_title：Vox sanguinis

authors： Mayer B,Salama A

更新日期：2017-11-01 00:00:00

abstract：:Radioimmunoassays were prepared using two anti-A and one anti-B reagents. The specificity of the procedures was assessed with 13 artificial antigens. The amounts of A and B natural antigens in saliva of ABH secretors of known Lewis phenotype were measured with these assays. The results confirmed that the average amoun...

journal_title：Vox sanguinis

authors： Le Pendu J,Lemieux RU,Dalix AM,Lambert F,Oriol R

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:IgG subclasses of anti-D seem to play some role in hemolytic disease of the newborn, but there has been disagreement as to its exact nature. The aim of our study was to evaluate a new technique for IgG subclassing of anti-D and to compare it to an established test. MATERIALS AND METHODS:In 31...

journal_title：Vox sanguinis

authors： Palfi M,Hildén JO

更新日期：1997-01-01 00:00:00

abstract：:2 patients on the drug azapropazone developed positive antiglobulin tests. Their sera were each found to contain two distinct antibodies. One was an IgG antibody, probably a drug-dependent autoantibody of the alpha-methyldopa type, but could have been related to the disease. The other was certainly a drug-dependent an...

journal_title：Vox sanguinis

authors： Bird GW,Wingham J,Babb RG,Bacon P,Wood D

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is a member of the coronavirus family. Coronavirus infections in humans are typically associated with respiratory illnesses; however, viral RNA has been isolated in...

journal_title：Vox sanguinis

authors： Keil SD,Ragan I,Yonemura S,Hartson L,Dart NK,Bowen R

更新日期：2020-08-01 00:00:00