A rapid automated latex screen for tetanus toxoid antibodies.

Abstract:

:This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection against tetanus. The techniques used for screening include immunoelectrophoresis [3], tetanus toxoid sensitised latex particles [5], haemagglutination [1] and automated haemagglutination [6]. The technique used by the Sheffield Regional Transfusion Centre until recently, was immunoelectrophoresis, selecting donors with 4 or more IU/ml. The Autotape system, previously described for brucellosis [4] and syphilis testing [2], provides a system for automated slide testing and a 5-min tetanus toxoid coated latex test has been developed to select suitable donations for the production of specific immunoglobulin.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Booth JR,Nuttall PA

doi

10.1111/j.1423-0410.1978.tb02474.x

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

239-40

issue

4

eissn

0042-9007

issn

1423-0410

journal_volume

34

pub_type

杂志文章
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    doi:10.1111/j.1423-0410.1998.tb05403.x

    authors: Gluckman E,Rocha V,Chastang C

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  • Children with AIDS.

    abstract::The etiologic agent for acquired immune deficiency syndrome (AIDS) has been identified as human T lymphotropic virus type III (HTLV-III). Its distinguishing characteristics and putative receptor, the T4 molecule, are discussed. The Western Blot method has been applied to assess the presence of antibody to HTLV-III in ...

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    doi:10.1111/j.1423-0410.1986.tb02005.x

    authors: Pahwa S

    更新日期:1986-01-01 00:00:00

  • Loss of phosphotyrosine phosphatase activity and changes in the tyrosine phosphorylation state of proteins after storage of sheep platelets in plasma or Seto solution at 4 degrees C.

    abstract:BACKGROUND AND OBJECTIVES:During platelet storage an array of deleterious changes occur, through mechanisms not fully understood, which impair platelet haemostasis. Transfused platelets should maintain the integrated networks of signalling pathways that regulate platelet activation and functionality. We hypothesized th...

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    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.2001.00111.x

    authors: Hernández-Hernández A,Sánchez-Bernal C,Rodríguez MC,Gómez FP,Llanillo M,Sánchez-Yagüe J

    更新日期:2001-11-01 00:00:00

  • Cold lymphocytotoxins. Chromatographical study.

    abstract::A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1976.tb02207.x

    authors: Mayer S,Hauptmann G,Tongio MM

    更新日期:1976-01-01 00:00:00

  • Riboflavin and amotosalen photochemical treatments of platelet concentrates reduce thrombus formation kinetics in vitro.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12231

    authors: Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

    更新日期:2015-05-01 00:00:00

  • Reduced risk of transfusion-transmitted HIV in Kenya through centrally co-ordinated blood centres, stringent donor selection and effective p24 antigen-HIV antibody screening.

    abstract:BACKGROUND:Following a 1994 study showing a high rate of transfusion-associated HIV, Kenya implemented WHO blood safety recommendations including: organizing the Kenya National Blood Transfusion Service (NBTS), stringent blood donor selection, and universal screening with fourth-generation p24 antigen and HIV antibody ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2010.01340.x

    authors: Basavaraju SV,Mwangi J,Nyamongo J,Zeh C,Kimani D,Shiraishi RW,Madoda R,Okonji JA,Sugut W,Ongwae S,Pitman JP,Marum LH

    更新日期:2010-10-01 00:00:00

  • Quantification by ELISA of erythrocyte-bound C3 fragments expressing C3d and/or C3c epitopes in patients with factor I deficiency and with autoimmune diseases.

    abstract::A sensitive ELISA assay for quantifying erythrocyte (E) bound C3 fragments was developed. The assay employs a double-antibody sandwich technique, using polyclonal anti-C3d or anti-C3c antibodies to quantify C3 fragments, expressing C3d and/or C3c epitopes in washed, detergent-solubilized E. The assay detected 50-120 m...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1989.tb02039.x

    authors: Møller Rasmussen J,Jepsen HH,Teisner B,Holmskov-Nielsen U,Rasmussen GG,Svehag SE

    更新日期:1989-01-01 00:00:00

  • A comparison of in vitro tests for predicting the severity of haemolytic disease of the fetus and newborn.

    abstract::Haemolytic disease of the newborn (HDN) is characterized by the presence of IgG antibodies in the maternal circulation which cause haemolysis in the fetus by crossing the placenta and sensitizing red cells for destruction by macrophages in the fetal spleen. Numerous serological, quantitative and cellular assays have b...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.1998.tb05445.x

    authors: Hadley AG

    更新日期:1998-01-01 00:00:00

  • Cytomegalovirus (CMV) antibody in male homosexuals: a source for CMV immune globulin.

    abstract::Male homosexuals have been found to have an extraordinarily high prevalence, and high titers, of antibodies to cytomegalovirus (CMV), as determined by complement-fixation and passive hemagglutination tests. These findings support other data suggesting that CMV may be sexually transmitted. The high titers of CMV antibo...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb01881.x

    authors: Ikram H,Prince AM,Baker LN

    更新日期:1983-03-01 00:00:00

  • Use of the MAIEA technique to confirm the relationship between the Cromer antigens and decay-accelerating factor and to assign provisionally antigens to the short-consensus repeats.

    abstract::The MAIEA (monoclonal-antibody-specific immobilisation of erythrocyte antigens) assay has recently been developed for the assignment of red cell antigens, recognised by human alloantisera, to particular membrane components of the red cell membrane. This technique detects trimolecular complexes formed by the reaction o...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1993.tb02172.x

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    更新日期:1993-01-01 00:00:00

  • The HLA system: an update and relevance to patient-donor matching strategies in clinical transplantation.

    abstract::In recent years the development of recombinant DNA and sequencing techniques has led to a greatly increased understanding of the genetic complexity, structure and function of the human major histocompatibility complex. This system may be subdivided into the "classical' HLA (human leukocyte antigen) class I and II tran...

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    pub_type: 杂志文章,评审

    doi:10.1046/j.1423-0410.1996.7110006.x

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  • Alloimmunization against Iy, a low-frequency antigen on platelet glycoprotein Ib/IX as a cause of severe neonatal alloimmune thrombocytopenic purpura.

    abstract::Neonatal alloimmune thrombocytopenia (NAIT) is usually induced by platelet-specific antibodies against HPA-1a (Zwa) or HPA-5b (Bra). Recently, low-frequency alloantigens on the platelet glycoprotein (GP) IIb/IIIa complex have been discovered as a cause for NAIT. In this report, a new low-frequency platelet-specific al...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1995.tb02604.x

    authors: Kiefel V,Vicariot M,Giovangrandi Y,Kroll H,Böhringer M,Greinacher A,Breitfeld C,Santoso S,Mueller-Eckhardt C

    更新日期:1995-01-01 00:00:00

  • Intrapatient comparison of an intermittent and a continuous flow cell separator for the collection of progenitor and stem cells from the blood.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:

    authors: Beretta F,van den Bosch S,Castelli D,Cavalli F,Ghielmini M

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  • Transfusion risk associated with recent arbovirus outbreaks in French Polynesia.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12855

    authors: Beau F,Mallet HP,Lastère S,Broult J,Laperche S

    更新日期:2020-02-01 00:00:00

  • Platelet concentrates. Influence of different preparative protocols on the in vitro release reaction.

    abstract::To determine what effect different preparative protocols and different platelet storage bags have on in vitro release, platelet concentrates were prepared according to two different protocols (group I: 2,200 g for 3.5 min followed by 4,900 g for 5 min; group II: 1,000 g for 9 min and 3,000 g for 20 min). The storage b...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:

    authors: Snyder EL,Koerner TA Jr,Hezzey A

    更新日期:1982-01-01 00:00:00

  • A new therapeutic antibody removal method using antigen-positive red cells. II. Application to a P-incompatible pregnant woman.

    abstract::Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1984.tb01589.x

    authors: Yoshida H,Ito K,Emi N,Kanzaki H,Matsuura S

    更新日期:1984-01-01 00:00:00

  • Plasmapheresis technology.

    abstract::Manual plasmapheresis is done worldwide on both paid donors, and to a much smaller extent on volunteer donors in order to generate source plasma to be fractionated into albumin, clotting factor concentrates, and gamma globulin. Automated technology has now been developed utilizing both centrifugal, and membrane separa...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1986.tb01992.x

    authors: Gilcher RO

    更新日期:1986-01-01 00:00:00

  • Detection of a new weak A blood-group allele (Aw11).

    abstract:BACKGROUND AND OBJECTIVES:Weak ABO variants may escape tests using unlicensed sera. MATERIALS AND METHODS:Prior to transfusion, ABO grouping was performed using an automated system and in-house diluted sera, and manual and bedside test techniques. Genotyping and sequencing were performed using standard methods. RESUL...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2006.00752.x

    authors: Pruss A,Heymann GA,Braun J,Kiesewetter HH,Salama A

    更新日期:2006-04-01 00:00:00

  • Severe neonatal alloimmune thrombocytopenia due to anti-HPA-3a.

    abstract:BACKGROUND AND OBJECTIVES:Neonatal alloimmune thrombocytopenia is usually attributable to HPA-la antibodies. We report a case of parental platelet antigen incompatibility associated with a severe neonatal thrombocytopenia secondary to alloimmunization to HPA-3a. MATERIALS AND METHODS:Platelet antibodies were detected ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:

    authors: Boehlen F,Kaplan C,de Moerloose P

    更新日期:1998-01-01 00:00:00

  • Factors related to allergic transfusion reactions and febrile non-haemolytic transfusion reactions in children.

    abstract:BACKGROUND AND OBJECTIVES:Allergic transfusion reactions (ATRs) and febrile non-haemolytic transfusion reactions (FNHTRs) are the two major types of transfusion-related adverse reactions (TRARs). Although prestorage leucocyte reduction and diversion of the first aliquot of blood (LR/D) could reduce FNHTRs and bacterial...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12373

    authors: Yanagisawa R,Shimodaira S,Sakashita K,Hidaka Y,Kojima S,Nishijima F,Hidaka E,Shiohara M,Nakamura T

    更新日期:2016-05-01 00:00:00

  • Functional antibacterial activity of a human intravenous immunoglobulin preparation: in vitro and in vivo studies.

    abstract::The functional antibacterial activity of an intravenous immunoglobulin preparation (Swiss Red Cross Immunoglobulin, SRK-Ig) was tested both in vitro and in vivo. Using type III group B streptococci as a model system, the intravenous immunoglobulin preparation was shown to enhance phagocytosis and killing of the bacter...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb04485.x

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    更新日期:1983-01-01 00:00:00

  • A new preparation of modified immune serum globulin (human) suitable for intravenous administration. II. Functional characterization.

    abstract::The commercial immune serum globulin (ISG) product is suitable for use in passive immunization only by intramuscular administration; intravenous use results in vasomotor side reactions. We report the functional characterization of a chemically modified ISG (MISG) that is essentially free of nonspecific complement-bind...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1981.tb00726.x

    authors: Schroeder DD,Tankersley DL,Lundblad JL

    更新日期:1981-01-01 00:00:00

  • Purification of human immunoglobulin G: a new approach to plasma fractionation.

    abstract:BACKGROUND AND OBJECTIVES:Currently, plasma fractionation involves multiple processing steps using established methods such as ethanol precipitation and column chromatography. The known limitations associated with conventional purification techniques, combined with strict regulations on safety and high demand for parti...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.2002.00241.x

    authors: Li G,Stewart R,Conlan B,Gilbert A,Roeth P,Nair H

    更新日期:2002-11-01 00:00:00

  • Patient-specific transfusion-related acute lung injury.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2007.00982.x

    authors: Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

    更新日期:2008-01-01 00:00:00

  • Effects of oral supplementation of iron on hepcidin blood concentrations among non-anaemic female blood donors: a randomized controlled trial.

    abstract:BACKGROUND AND OBJECTIVES:Hepcidin is the main hormone that regulates iron balance. Its lowering favours digestive iron absorption in cases of iron deficiency or enhanced erythropoiesis. The careful dosage of this small peptide promises new diagnostic and therapeutic strategies. Its measurement is progressively being v...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/vox.12348

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  • The Sdx antigen and antibody: biochemical studies on the inhibitory property of human urine.

    abstract::Anti-Sdx is an IgM complement-binding autoantibody that defines a red cell antigen which is independent of I, i, Sp1 (Pr) and Gd. Hemagglutination by the antibody is unusually sensitive to variation in pH, salt, or other charged molecular species. The antibody is inhibited by urine from Sd(a+) persons, but inhibition ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb01884.x

    authors: Bass LS,Rao AH,Goldstein J,Marsh WL

    更新日期:1983-03-01 00:00:00

  • Evaluation of two different protocols for peripheral blood stem cell collection with the Fresenius AS 104 blood cell separator.

    abstract:OBJECTIVES:Reconstitution of hematopoiesis by means of peripheral blood stem cells is a valid alternative to autologous bone marrow transplantation. The aim of this investigation was to increase the efficiency of collection of circulating blood progenitor cells and to obtain a purer product for transplant. METHODS:We ...

    journal_title:Vox sanguinis

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1423-0410.1997.7340230.x

    authors: Menichella G,Lai M,Pierelli L,Vittori M,Serafini R,Ciarli M,Foddai ML,Salerno G,Sica S,Scambia G,Leone G,Bizzi B

    更新日期:1997-01-01 00:00:00

  • Anticore antibody screening of transfused blood.

    abstract::Aliquots of 130 HB8Ag negative units of blood which were administered to 26 recipients were tested under code for anti-HBc by a solid phase radioimmunoassay technqiue. 14 of the 26 recipients developed posttransfusion hepatitis (PTH), including 6 cases of hepatitis B. Anti-HBc was detected in 7 or 5.3% of 130 donor un...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1978.tb03726.x

    authors: Lander JJ,Gitnick GL,Gelb LH,Aach RD

    更新日期:1978-01-01 00:00:00

  • Transfusion results of filtered and subsequently stored random platelet suspensions prepared from buffy coats.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1992.tb01214.x

    authors: Novotny VM,van Doorn R,Rozier Y,D'Amaro J,Harvey MS,Brand A

    更新日期:1992-01-01 00:00:00

  • Fluid motion and shear forces in platelet storage bags with different modes of agitation.

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    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12409

    authors: Torres R,Tormey CA,Stack G

    更新日期:2016-08-01 00:00:00