Abstract:
:This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection against tetanus. The techniques used for screening include immunoelectrophoresis [3], tetanus toxoid sensitised latex particles [5], haemagglutination [1] and automated haemagglutination [6]. The technique used by the Sheffield Regional Transfusion Centre until recently, was immunoelectrophoresis, selecting donors with 4 or more IU/ml. The Autotape system, previously described for brucellosis [4] and syphilis testing [2], provides a system for automated slide testing and a 5-min tetanus toxoid coated latex test has been developed to select suitable donations for the production of specific immunoglobulin.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Booth JR,Nuttall PAdoi
10.1111/j.1423-0410.1978.tb02474.xsubject
Has Abstractpub_date
1978-01-01 00:00:00pages
239-40issue
4eissn
0042-9007issn
1423-0410journal_volume
34pub_type
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