Impact of donor arm skin disinfection on the bacterial contamination rate of platelet concentrates.

abstract：:The Gm allotype constitution of the autoantibody molecules and the serum Gm phenotypes were determined in 19 patients with autiommune hemolytic anemia of IgG type. The results showed that the known heterogeneity of the antierythrocyte autoantibodies in this disease concerns not only the immunoglobulin class and the is...

journal_title：Vox sanguinis

authors： Le Petit JC,Rivat L,François N,Ropartz C,Brizard CP

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We identified some fatal cases where massively bleeding patients received inadequate transfusion therapy. The aim of this study was to review and evaluate the transfusion practice in acutely multitransfused patients. MATERIALS AND METHODS:Patients receiving > 10 units of red blood cells (RBC)...

journal_title：Vox sanguinis

authors： Johansson PI,Hansen MB,Sørensen H

更新日期：2005-08-01 00:00:00

abstract：:The formation of mono(ethylhexyl)phthalate (MEHP) from di(ethylhexyl)phthalate in human plasma stored in bags of polyvinylchloride has been studied. Substantial amounts were formed and in ten bags from 4 to 56microgram/ml were found. After 2 weeks at room temperature the concentration of MEHP had increased to values b...

journal_title：Vox sanguinis

authors： Vessman J,Rietz G

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A dramatic decrease in the level of 2,3-diphosphoglycerate (2,3-DPG) takes place during the storage of whole blood (WB) in CPDA (citrate-phosphate-dextrose-adenine) and a similar decrease occurs during the storage of red blood cells (RBCs) in SAGM (saline-adenine-glucose-mannitol). The aim of ...

journal_title：Vox sanguinis

authors： Kurup PA,Arun P,Gayathri NS,Dhanya CR,Indu AR

更新日期：2003-11-01 00:00:00

abstract：:Sera obtained from 4 mothers of children with neonatal alloimmune thrombocytopenia contained a platelet-specific alloantibody, anti-Bra, which defined an antigen apparently different from all known platelet alloantigens. All 4 fathers were Bra positive, whereas all mothers were Bra negative. The minimal postnatal valu...

journal_title：Vox sanguinis

authors： Kiefel V,Santoso S,Katzmann B,Mueller-Eckhardt C

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The occurrence of thromboembolic events (TEEs) with intravenous immunoglobulin lots (IVIGs) raised the question of the causative agent for these adverse events. We investigated the predominant plasma proteases in 19 IVIG lots from five manufacturers including three lots associated with adverse...

journal_title：Vox sanguinis

authors： Etscheid M,Breitner-Ruddock S,Gross S,Hunfeld A,Seitz R,Dodt J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to investigate the effects of extended storage of pooled random platelets in SSP+ additive solution (MacoPharma). MATERIALS AND METHODS:Eight buffy coat-derived, pooled, leucoreduced platelet concentrates were prepared in 75% SSP+, 25% plasma using Fresenius/NPBI Com...

journal_title：Vox sanguinis

authors： Hornsey VS,McColl K,Drummond O,McMillan L,Morrison A,Morrison L,MacGregor IR,Prowse CV

更新日期：2006-07-01 00:00:00

abstract：:Spectrophotometric and gas-liquid chromatographic analyses on the carbohydrate moiety of tryptic erythrocyte glycopeptides from persons with Tn-syndrome reveal a selective lowering of the galactose and sialic acid content, the degree being dependent on the percentage of polyagglutinable cells. Alkaline borohydride spe...

journal_title：Vox sanguinis

authors： Dahr W,Uhlenbruck G,Gunson HH,Van Der Hart M

更新日期：1975-01-01 00:00:00

abstract：:The effect on cryoprecipitate factor VIII recovery of three imortant variables has been investigated. The design of the study was such as to eliminate, for the purpose of internal comparisons, spurious effects such as those due to the variation in factor VIII levels in donor plasma. The choice of anticoagulant was sho...

journal_title：Vox sanguinis

authors： Wensley RT,Snape TJ

更新日期：1980-01-01 00:00:00

abstract：:Interest in immunogenetics originated from two streams: (a) histocompatibility in mouse and man, and (b) inheritance of specific immune responses in the guinea pig and mouse. In the mouse, there are genes associated with the major histocompatibility complex (MHC) which (i) code for antigens determining allograft respo...

journal_title：Vox sanguinis

authors： Mackay IR,Wittingham S,Tait B

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Transfusion Requirements In Critical Care (TRICC) study found that critically ill patients tolerate a restrictive haemoglobin transfusion threshold. We investigated red-cell transfusion practice since publication of the TRICC study in a large Scottish teaching hospital intensive care unit ...

journal_title：Vox sanguinis

authors： Chohan SS,McArdle F,McClelland DB,Mackenzie SJ,Walsh TS

更新日期：2003-04-01 00:00:00

abstract：:IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infect...

journal_title：Vox sanguinis

authors： Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström T

更新日期：1986-01-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：:Plasmodium falciparum malaria has long been a killer of the young, and has selected for polymorphisms affecting not only erythrocytes, but the immunogenetics of three histocompatibility systems: ABO, human leukocyte antigen (HLA), and CD36. The ABO system is important because the original allele, encoding glycosylatio...

journal_title：Vox sanguinis

authors： Cserti-Gazdewich CM,Mayr WR,Dzik WH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. MATERIAL AND METHODS:To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets conce...

journal_title：Vox sanguinis

authors： Brito F,Cordey S,Delwart E,Deng X,Tirefort D,Lemoine-Chaduc C,Zdobnov E,Lecompte T,Kaiser L,Waldvogel-Abramowski S,Preynat-Seauve O

更新日期：2018-07-18 00:00:00

abstract：:A new granulocyte collection method employing discontinuous flow centrifugation and low donor dose of hydroxyethyl starch (HES) is presented. Following the procedure, the increase in serum polysaccharide concentration was 100 mg/dl, about 20% of that seen after standard discontinuous flow leukapheresis. The average ef...

journal_title：Vox sanguinis

authors： Szymanski IO

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. METHODS:Donation (n = 180)...

journal_title：Vox sanguinis

authors： Feys HB,Coene J,Devloo R,Van Aelst B,Pottel H,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：:Because substrate specificities differ between proteolytic enzymes and because knowledge of the optimal enzyme activity levels is necessary in order to standardize procedures used in antibody screening, a study was made of the best common assay method for the routinely employed enzymes bromelain, papain and ficin. Cas...

journal_title：Vox sanguinis

authors： Ogasawara K,Mazda T

更新日期：1989-01-01 00:00:00

abstract：:We developed a new filter, 'Sepacell-PL', consisting of a blood administration set for the preparation of leukocyte-poor platelet concentrates at the patient's bedside. This filter is packed with 1.8 microns polyester fibers coated with a new polymer, and has a volume of 14 ml. Sepacell-PL removed more than 99% of the...

journal_title：Vox sanguinis

authors： Miyamoto M,Sasakawa S,Ishikawa Y,Ogawa A,Nishimura T,Kuroda T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is concern regarding the lack of prevention of unnecessary transfusion of RhD negative red cells and unnecessary administration of Rh immunoglobulin (RhIG) to pregnant women. In this study, performance of ID RHD XT, a genotyping assay for identification of six RHD allelic variants and hu...

journal_title：Vox sanguinis

authors： Londero D,Monge J,Hellberg A

更新日期：2020-04-01 00:00:00

abstract：:A number of parasitic diseases are known, or suspected to be transmitted by blood transfusion. Of greatest concern are malaria and Chagas' disease, but babesia, leishmania and toxoplasmosis also offer risk in particular locations or circumstances. Some of these parasites may be imported into non-endemic areas as a res...

journal_title：Vox sanguinis

authors： Dodd RY

更新日期：1998-01-01 00:00:00

abstract：:Pst I endonuclease fragment length polymorphism of the antithrombin III probe was studied in a French population. Among 25 subjects tested, 15 were found heterozygous at the Pst I site, so that this polymorphism might serve as a useful markers of antithrombin III gene in families with antithrombin III deficiency. ...

journal_title：Vox sanguinis

authors： Le Paslier D,Rochu D,Lucotte G

更新日期：1985-01-01 00:00:00

abstract：:Acute posttransfusion hepatitis C was reported in a recipient of 3 units of red cells. The recipient became acutely icteric 6 weeks after transfusion, and HCV infection was diagnosed. Stored serum samples of the 3 implicated donations, which were negative with ELISA-2, were retested by PCR and 3rd-generation antibody ...

journal_title：Vox sanguinis

authors： Vrielink H,van der Poel CL,Reesink HW,Zaaijer HL,Lelie PN

更新日期：1995-01-01 00:00:00

abstract：:The human Lewis gene encodes an alpha(1,3/1,4)-fucosyltransferase responsible for synthesis of the Le(a) and a Le(b) antigens. To define the molecular background for non-functional Lewis genes we have sequenced PCR-amplified DNA fragments from two Le(a-b-) individuals. One was homozygously mutated at nucleotides 202(T...

journal_title：Vox sanguinis

authors： Elmgren A,Börjeson C,Svensson L,Rydberg L,Larson G

更新日期：1996-01-01 00:00:00

abstract：:A Bombay, Le(a-b-) saliva was shown to lack Pneumococcus type XIV activity, an unusual situation, since this sample should be rich in this precursor to the ABO blood group substances. However, the sample was found to contain a new serological specificity, Le-c. It is argued that simple Mendelian inheritance does not o...

journal_title：Vox sanguinis

authors： Savvas RS

更新日期：1975-01-01 00:00:00

abstract：:A group B recipient of a group 0 kidney developed severe intravascular haemolysis due to the formation of anti-B. Immunoglobulin allotyping of donor serum, recipient serum and 'unexpected' anti-B antibody showed the antibody to be of donor origin. The patient and donor genotypes were Gm 3;5/3;5 and Gm 1,2;21/1;21, res...

journal_title：Vox sanguinis

authors： Orchard J,Young NT,Smith C,Thomas S,Darke C

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The amino acid substitutions caused by ABO gene variants are usually predicted to impact the glycosyltransferase function. Here, the effect of an amino acid substitution in the vicinity of the catalytic active region of the B-glycosyltransferase was explored in vitro and in silico study, which is important f...

journal_title：Vox sanguinis

authors： Ying Y,Hong X,Xu X,Zhang J,He J,Zhu F,Xie X

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The molecular basis of the weak D phenotype has been investigated for many years, and more than 80 different alleles producing weak D phenotypes have been identified. Most alleles producing weak D phenotypes have a single missense mutation in exons corresponding to a transmembrane domain of th...

journal_title：Vox sanguinis

authors： Ogasawara K,Sasaki K,Isa K,Tsuneyama H,Uchikawa M,Satake M,Tadokoro K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Host- or donor-derived alloimmune thrombocytopenia can develop after non-myeloablative allogeneic haematopoietic stem cell transplantation (HSCT). We report the first case of host-derived HPA-1a antibodies. CASE REPORT:A 52-year-old male patient received HSCT from his human leucocyte antigen ...

journal_title：Vox sanguinis

authors： Macher S,Schallmoser K,Staber PB,Neumeister P,Posch U,Lanzer G,Panzer S

更新日期：2005-11-01 00:00:00