Abstract:
:We developed a new filter, 'Sepacell-PL', consisting of a blood administration set for the preparation of leukocyte-poor platelet concentrates at the patient's bedside. This filter is packed with 1.8 microns polyester fibers coated with a new polymer, and has a volume of 14 ml. Sepacell-PL removed more than 99% of the leukocytes while approximately 93% of platelets were recovered from 10 units of platelet concentrates which contained 5 x 10(8) leukocytes and 3 x 10(11) platelets. The functions of pre- and postfiltrated platelets were unchanged. The filtration procedure is very simple, without priming with saline to remove air and wet the filter. Moreover, platelet concentrates can be passed through the filter at a flow rate of 4 ml/min, or at a higher flow rate of 54 ml/min by gravity.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Miyamoto M,Sasakawa S,Ishikawa Y,Ogawa A,Nishimura T,Kuroda Tdoi
10.1111/j.1423-0410.1989.tb00815.xsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
164-7issue
3eissn
0042-9007issn
1423-0410journal_volume
57pub_type
杂志文章相关文献
VOX SANGUINIS文献大全abstract:BACKGROUND AND OBJECTIVES:In order to preserve platelet concentrates (PCs) with high yields, a new polyolefin platelet storage container (PL 2410, 1.3L, Baxter, La Châtre, France) with increased gas permeability in combination with a larger surface area has been developed. The storage capacity was studied with platelet...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:The risk of transmitting hepatitis C (HCV) by transfusion of anti-HCV-negative screened blood was estimated for the blood donor population of Baden-Württemberg (southwestern Germany). METHODS:The data from the blood donors screened for anti-HCV and for HBsAg during 1990-1995 were analyzed. RESULTS:The preva...
journal_title:Vox sanguinis
pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-01-01 00:00:00
abstract::An attempt was made to confirm a previously reported association between HLA type B16 and resistance to infection with live attenuated influenza A virus vaccine. No differences were found either in the ability of influenza virus to attach to fractionated white blood cells from HLB B16 subjects compared to cells from s...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1979.tb02292.x
更新日期:1979-01-01 00:00:00
abstract::Following transfusion, red cells labeled with nonradioactive chromium (52Cr) can be detected in the circulation using atomic absorption spectrophotometry. Both in rhesus monkeys and in human subjects, the survival of red cells labeled with 52Cr was found to be insignificantly different from that of cells labeled with ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1990.tb02091.x
更新日期:1990-01-01 00:00:00
abstract::A method to coat unsensitized erythrocytes with fragments of C3 and C4 using autologous serum, in order to study complement receptor-dependent function of the fixed macrophage system, is presented. After incubation with serum under optimal conditions, at least 90% of the cells had C3b/iC3b deposited on the surface, wi...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1991.tb00926.x
更新日期:1991-01-01 00:00:00
abstract::One of the most controversial policies in blood transfusion worldwide is the permanent deferral from donating blood of men with sexual contacts to other men (MSM). This policy was implemented for safety reasons as sex between men is known to be a high risk factor for acquiring severe infectious diseases transmissible ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12179
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The occurrence of thromboembolic events (TEEs) with intravenous immunoglobulin lots (IVIGs) raised the question of the causative agent for these adverse events. We investigated the predominant plasma proteases in 19 IVIG lots from five manufacturers including three lots associated with adverse...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.2011.01502.x
更新日期:2012-01-01 00:00:00
abstract::In this prospective study, 26 consecutive patients being treated for haematological malignancies receiving standard (i.e. non-leucocyte-depleted) blood components were observed for the development of refractoriness to platelet transfusions. One hundred and sixteen of the 266 (44%) platelet transfusions failed to produ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1994.tb00310.x
更新日期:1994-01-01 00:00:00
abstract::Alpha1-Acid glycoprotein (orosomucoid) was prepared from a byproduct of the ethanol plasma fractionation by means of ion-exchange procedures. Immunoelectrophoresis suggested a high degree of purity; the purified protein contained 13.5% sialic acid and 17.8% hexose. The alpha1-acid glycoprotein was modified by removal ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1976.tb02846.x
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:HPA-1a antibodies account for 70-80% of cases of fetal-neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians. However, numerous workshops have demonstrated variability in their detection. We recently showed that exposure of αIIbβ3 to ethylene diamine tetraacetic acid (EDTA) affected bindi...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12043
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Red-blood-cell (RBC) transfusion is associated with lung injury, which is further exacerbated by mechanical ventilation. Manufacturing methods of blood products differ globally and may play a role in the induction of pulmonary cell activation through alteration of the immunomodulatory property...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12911
更新日期:2020-07-01 00:00:00
abstract::Platelet function in thrombosis and haemostasis is reasonably well understood at the molecular level with respect to the proteins involved in cellular structure, signalling networks and platelet interaction with clotting factors and other cells. However, the natural history of these proteins has only recently garnered...
journal_title:Vox sanguinis
pub_type: 杂志文章,评审
doi:10.1111/j.1423-0410.2010.01333.x
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Variant RHD genes associated with the weak D phenotype can result in complete or partial D-epitope expression on the red cell. This study examines the genetic classification in Australian blood donors with a weak D phenotype and correlates RHD variants associated with the weak D phenotype agai...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12488
更新日期:2017-04-01 00:00:00
abstract::The second example of anti-F1 cold agglutinins recognizing a developmentally regulated antigen like I is described. The antibody occurred transiently and simultaneously together with an anti-I cold agglutinin. Although anti-F1 and anti-I specificities are entirely different, the data on the biochemistry of F1 and I an...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1984.tb01573.x
更新日期:1984-01-01 00:00:00
abstract::We tested serum samples from 11 HIV-seropositive and 32 HIV-seronegative Italian patients with hemophilia A or B for the presence of lymphocytotoxic antibodies (LCTAs). No patients had the acquired immune deficiency syndrome and all had received over many years heat-untreated commercial clotting factors. LCTAs directe...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1988.tb01612.x
更新日期:1988-01-01 00:00:00
abstract::The domain specificity of anti-factor VIII (FVIII) inhibitor antibodies was determined in assays using FVIII domains generated by thrombin cleavage or expressed as recombinant polypeptides to neutralise the inhibitor. The results revealed the existence of three major types of inhibitors, and various combinations of th...
journal_title:Vox sanguinis
pub_type: 杂志文章,评审
doi:10.1159/000056708
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Transfusion of fresh-frozen plasma is still a pillar in emergency medicine for using to prevent dilutional coagulopathy or disseminated intravascular coagulation after severe blood loss, but thawing procedures can delay its availability. On the other hand, the wastage of plasma, once thawed an...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.2004.00552.x
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Whole blood is stored at room temperature (RT) until processing into components. After separation and filtration, the RCC has to be cooled from RT to +2 - 6°C. Different start times of the cooling process and different cooling rates can be encountered in daily routine. The effect of these parameters of the i...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.2010.01458.x
更新日期:2011-07-01 00:00:00
abstract::A substantial body of animal data indicates that transmissible spongiform encephalopathies (TSEs) are transmitted through blood. These data have been augmented in the past year by reports that two recipients of red cells from donors with variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom have acquired this...
journal_title:Vox sanguinis
pub_type: 杂志文章,评审
doi:10.1111/j.1423-0410.2005.00702.x
更新日期:2005-11-01 00:00:00
abstract::Paraformaldehyde-fixed platelets from normal donors were used for detection of antibody to platelet by in vitro sensitization (indirect method) utilizing rabbit anti-human IgG heavy chain specific antibody-coated polyacrylamide gels (Immunobeads). The sensitized platelets formed rosettes with Immunobeads and the posit...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1980.tb01869.x
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Polymorphonuclear neutrophils (PMNs) play important roles in the host immune defence. This study was performed to identify roles of PMNs other than those already known. MATERIALS AND METHODS:PMNs were separated from the peripheral blood of healthy individuals and stored in vitro for 24 h in t...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1046/j.1423-0410.2002.00156.x
更新日期:2002-04-01 00:00:00
abstract::Sera obtained from 4 mothers of children with neonatal alloimmune thrombocytopenia contained a platelet-specific alloantibody, anti-Bra, which defined an antigen apparently different from all known platelet alloantigens. All 4 fathers were Bra positive, whereas all mothers were Bra negative. The minimal postnatal valu...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1988.tb01625.x
更新日期:1988-01-01 00:00:00
abstract::An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual ex...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/j.1423-0410.1985.tb00189.x
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Allergic transfusion reactions (ATRs) and febrile non-haemolytic transfusion reactions (FNHTRs) are the two major types of transfusion-related adverse reactions (TRARs). Although prestorage leucocyte reduction and diversion of the first aliquot of blood (LR/D) could reduce FNHTRs and bacterial...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12373
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Inaccuracy of fingerstick haemoglobin compromises donor's health and losses blood donations. We evaluated the benefit of double haemoglobin screening with HemoCue. STUDY DESIGN AND METHODS:Blood donors underwent fingerstick screening by HemoCue and were driven for donation if capillary haemog...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12165
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:A 2-year-old female with neuroblastoma needed In(b-), E- red blood cells (RBCs). No units were available at the blood centre (BC) nor in the rare donor programme member's inventories. BC's Immunohematology Reference Laboratory (IRL) and its marketing department concentrated on recruiting and t...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.13053
更新日期:2020-12-21 00:00:00
abstract::Interest in immunogenetics originated from two streams: (a) histocompatibility in mouse and man, and (b) inheritance of specific immune responses in the guinea pig and mouse. In the mouse, there are genes associated with the major histocompatibility complex (MHC) which (i) code for antigens determining allograft respo...
journal_title:Vox sanguinis
pub_type: 历史文章,杂志文章
doi:10.1111/j.1423-0410.1977.tb00598.x
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:The absence of the red cell antigens P, P1 and Pk , known as 'p', represents an extremely rare red cell phenotype. Individuals with this phenotype spontaneously form anti-PP1Pk isoantibodies, associated with severe haemolytic transfusion reactions, recurrent spontaneous abortion and haemolytic disease of the...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.13042
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Partially replacing plasma with additive solutions in platelet (PLT) concentrates (PCs) may help to reduce transfusion reactions. Constituents of PLT additive solutions (PASs) have been revealed to affect the quality of PCs. Previous studies involved pairwise comparison of identical PLTs with ...
journal_title:Vox sanguinis
pub_type: 杂志文章
doi:10.1111/vox.12064
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Repeated blood donation produces iron deficiency. Changes in dietary iron intake do not prevent donation-induced iron deficiency. Prolonging the interdonation interval or using oral iron supplements can mitigate donation-induced iron deficiency. The most effective operational methods for reduc...
journal_title:Vox sanguinis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/vox.12210
更新日期:2015-02-01 00:00:00