Platelets stored in a new-generation container differences between plasma and platelet additive solution II.

abstract：BACKGROUND:Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. METHODS:Donation (n = 180)...

journal_title：Vox sanguinis

authors： Feys HB,Coene J,Devloo R,Van Aelst B,Pottel H,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to assess potentially relevant clinical characteristics which influence the decision to transfuse red cells in critically ill patients with low haemoglobin concentrations (6.0-10.0 g/dl). MATERIALS AND METHODS:This was a retrospective observational cohort study of pa...

journal_title：Vox sanguinis

authors： Kranenburg FJ,le Cessie S,Caram-Deelder C,van der Bom JG,Arbous MS

更新日期：2019-11-01 00:00:00

abstract：:Tissue oxygen delivery depends on red blood cell (RBC) content and RBC flow regulation in the microcirculation. The important role of the RBC in tissue oxygenation is clear from anaemia and the use of RBC transfusion which has saved many lives. Whether RBC transfusion actually restores tissue oxygenation is difficult ...

journal_title：Vox sanguinis

authors： Raat NJ,Ince C

更新日期：2007-07-01 00:00:00

abstract：:Anti-HBc is the most sensitive indicator of current or recent hepatitis B virus infection, hence its detection is valuable in laboratory diagnosis of the infection. Dane particles isolated from the plasma of a single chronic carrier and his autologous IgG labeled with 125I were utilized in a solid-phase sandwich radio...

journal_title：Vox sanguinis

authors： Vyas GN,Roberts IM

更新日期：1977-12-01 00:00:00

abstract：:With regard to hemostasis and thrombosis, collagens are among the most important physiologic components of the extracellular matrix in their role as platelet activators. Differences in the rate of platelet activation markedly influence normal hemostasis and the pathological outcome of thrombosis. Thus, collagen recept...

journal_title：Vox sanguinis

authors： Kunicki TJ,Nugent DJ

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies to the core of hepatitis B virus (anti-HBc) are considered to be the best serologically reliable markers of hepatitis B virus (HBV) infection. Through a national epidemiological survey, two young and first-time blood donors, originating from HBV-endemic areas, were identified as HBV...

journal_title：Vox sanguinis

authors： Laperche S,Guitton C,Smilovici W,Courouce AM

更新日期：2001-02-01 00:00:00

abstract：:Recently, the polymorphism of a new human platelet antigen, Ca/Tu, was shown to be derived from a G-A nucleotide substitution at base 1564 of GPIIIa cDNA, which leads to a single amino acid difference, Arg/Gln at amino acid 489 of GPIIIa. We developed a PCR-RFLP method to determine the genotypes of Ca/Tu and their fre...

journal_title：Vox sanguinis

authors： Tanaka S,Taniue A,Nagao N,Tomita T,Ohnoki S,Shibata H,Okubo Y,Yamaguchi H,Shibata Y

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study. METHODS:The progression to AIDS in relation to type of haemophilia,...

journal_title：Vox sanguinis

authors： Roosendaal G,van der Schouw Y,Mauser-Bunschoten E,Borleffs J,van den Berg H

更新日期：1998-01-01 00:00:00

abstract：:An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual ex...

journal_title：Vox sanguinis

authors： Dinning G,Doughty RW,Collins AK

更新日期：1985-01-01 00:00:00

abstract：:Mild as well as strong periodate oxidation of isolated erythrocyte N and M glycoproteins and glycopeptides gave extensive to complete destruction of N-specificities as measured with Vicia graminea extracts and of N- as well as M- activities determined with all but 1 of 8 animal anti-N and 13 anti-M sera. Results with ...

journal_title：Vox sanguinis

authors： Springer GF,Yang HJ

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...

journal_title：Vox sanguinis

authors： Beckman N,Cardigan R,Wallington T,Williamson LM

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Individual genomic screening for viruses in blood donations is becoming increasingly pressing as an alternative to pool testing to improve the safety of the blood supply. MATERIALS AND METHODS:To determine the feasibility and, possibly, efficacy of genomic screening for hepatitis C virus (HCV...

journal_title：Vox sanguinis

authors： Petrik J,Hewitt P,Barbara J,Allain J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...

journal_title：Vox sanguinis

authors： Borzini P,Riva M,Nembri P,Rossi E,Pagliaro P,Vergani P,Greppi P,Tantardini P

更新日期：1997-01-01 00:00:00

abstract：:Platelet function in thrombosis and haemostasis is reasonably well understood at the molecular level with respect to the proteins involved in cellular structure, signalling networks and platelet interaction with clotting factors and other cells. However, the natural history of these proteins has only recently garnered...

journal_title：Vox sanguinis

authors： Schubert P,Devine DV

更新日期：2010-08-01 00:00:00

abstract：:Balb/c mice were immunized with acquired B red cells. Twelve clones specific for acquired B red cells were obtained from two fusions. A detailed investigation of three clones is reported here. These antibodies appear to be directed to the B-like epitope since they are inhibited by galactosamine and fail to react after...

journal_title：Vox sanguinis

authors： Janvier D,Veaux S,Reviron M,Guignier F,Benbunan M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age. MATERIALS AND METHODS:Preterm infants receiving blood transfusion were recruited to three groups: 1-7 (group 1; n = 20), 8-...

journal_title：Vox sanguinis

authors： Banerjee J,Leung TS,Aladangady N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anti-CD38 monoclonal antibodies, including daratumumab and isatuximab, often interfere with pretransfusion testing. Dithiothreitol (DTT) treatment of red blood cells (RBCs) negates this interference. However, the optimum DTT concentration and treatment time have not been well defined. Here, we...

journal_title：Vox sanguinis

authors： Furumaki H,Takeshita A,Ohto H,Yamada C,Fujihara H,Ishizuka K,Shibata H,Shinba T,Nemoto N,Ino K,Ozawa A,Watanabe H,Kawabata K,Obata Y

更新日期：2020-12-13 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Refrigerated storage of red blood cells (RBCs) induces numerous changes that may target the cells for erythrophagocytosis following transfusion. The influence of storage upon the phagocytosis of unseparated and fractionated young and old stored RBCs was investigated using two in vitro quantita...

journal_title：Vox sanguinis

authors： Veale MF,Healey G,Sparrow RL

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Since July 1 1999, four laboratories in the Netherlands have been routinely screening plasma minipools for the release of labile blood components utilizing hepatitis C virus nucleic acid amplification technology (HCV NAT). This report describes the performance evaluation of the HCV NAT method ...

journal_title：Vox sanguinis

authors： Cuijpers HT,Molijn MH,Bos HJ,Peeters AP,van der Poel CL,Lelie PN

更新日期：2001-07-01 00:00:00

abstract：:A selected group of women previously immunized in pregnancy by the Rh(D) antigen were boosted with 0.5 ml of Rh(D)-positive frozen recovered red cells from an accredited donor panel. The response was prompt and sustained and increased the anti-D content by almost 10-fold. In spite of the reduced rate of clinical immun...

journal_title：Vox sanguinis

authors： Gabra GS,Black M,Mitchell R

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In peripheral blood stem cell transplantation, the number of CD34(+) cells infused is considered a predictor of haematopoietic engraftment. However, the currently accepted minimal threshold of CD34(+) cells/kg was determined by counting CD34(+) cells before freezing, and the loss of viable CD3...

journal_title：Vox sanguinis

authors： Lee S,Kim S,Kim H,Baek EJ,Jin H,Kim J,Kim HO

更新日期：2008-02-01 00:00:00

abstract：:A substantial body of animal data indicates that transmissible spongiform encephalopathies (TSEs) are transmitted through blood. These data have been augmented in the past year by reports that two recipients of red cells from donors with variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom have acquired this...

journal_title：Vox sanguinis

authors： Farrugia A,Ironside JW,Giangrande P

更新日期：2005-11-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：:The presence of IgM antibodies to human immunodeficiency virus 1 (HIV-1) was investigated in blood donor sera which were indeterminate in anti-HIV-1 IgG Western blot testing. In 7 of 173 instances out of approximately 1,000,000 blood donation sera with an isolated anti-p24 IgG produced an anti-gp41-45 IgM immunoblot r...

journal_title：Vox sanguinis

authors： Knüver-Hopf J,Heinze H,Lambrecht B,Mohr H,Beyer J,Schmitt H

更新日期：1993-01-01 00:00:00

abstract：:2,140 pregnant Sudanese women attending the antenatal clinic in Omdurman Maternity Hospital during the period November 1975 to December 1976 had ABO and Rh typing performed. Their sera were also screened by a modified papain enzyme technique for the presence of atypical antibodies. The rate of Rhesus immunization, the...

journal_title：Vox sanguinis

authors： Abu-Sin AY,Ayoub M,Abdelrazig H

更新日期：1978-01-01 00:00:00

abstract：:A large 81 member, four-generation black family with hereditary angioedema is reported with regards to its clinical course and the association with the histocompatibility system. No mortality was seen related directly to the disease. Assuming that this trait is autosomal dominant it appeared to have no linkage with th...

journal_title：Vox sanguinis

authors： Blumenthal MN,Dalmasso AP,Roitman B,Kelly J,Noreen H,Emmy L,Mendell NR,Yunis EJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:A disposable set for platelet concentrate (PC) preparation by the buffy coat method allows pooling of buffy coats, centrifugation and cell separation with in-line leucocyte filtration. This study compares three commercially available pooling sets in combination with INTERCEPT pathogen inactivation (PI). MAT...

journal_title：Vox sanguinis

authors： Feys HB,Devloo R,Sabot B,Coene J,Compernolle V

更新日期：2018-05-24 00:00:00

abstract：:Marrow transplantation is increasing, hematopoietic stem cells are being obtained from a wider variety of donors, and the cells almost always undergo some processing steps. These activities, along with the hematologic complexities of marrow transplant patients, create many varied opportunities for blood centers. ...

journal_title：Vox sanguinis

authors： McCullough J

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:GB virus C (GBV-C)/hepatitis G virus (HGV) is a recently recognized parenterally and sexually transmitted agent. The prevalence of GBV-C/HGV markers in Canadian blood donors has not been previously studied and was therefore determined. MATERIALS AND METHODS:Blood donors [identity unlinked (IU...

journal_title：Vox sanguinis

authors： Giulivi A,Slinger R,Tepper M,Sher G,Scalia V,Kessler G,Gill P

更新日期：2000-01-01 00:00:00