An improved method to study complement receptor-mediated function of the fixed macrophage system in vivo.

abstract：:Early and regular blood transfusion therapy in patients with homozygous beta-thalassaemia decreases the complications of severe anaemia and prolongs survival. In the long term, however, the beneficial effects of transfusions are limited by the organ damage resulting from iron overload, a consequence of the body's limi...

journal_title：Vox sanguinis

authors： Prati D

更新日期：2000-01-01 00:00:00

abstract：:An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual ex...

journal_title：Vox sanguinis

authors： Dinning G,Doughty RW,Collins AK

更新日期：1985-01-01 00:00:00

abstract：:Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal anaemia with a risk for fetal death and to severe forms of neonatal hyperbilirubinaemia with a risk for kernicterus. Most severe cases are caused by anti-D,...

journal_title：Vox sanguinis

authors： de Haas M,Thurik FF,Koelewijn JM,van der Schoot CE

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study. METHODS:The progression to AIDS in relation to type of haemophilia,...

journal_title：Vox sanguinis

authors： Roosendaal G,van der Schouw Y,Mauser-Bunschoten E,Borleffs J,van den Berg H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The non-paired two-arm study compared the in vitro storage characteristics of platelets suspended as concentrates in either 100% plasma or a mixture of additive solution (SSP+™, MacoPharma, Mouveaux, France) and autologous plasma in a 70:30 ratio over a 14-day storage period. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Saunders C,Rowe G,Wilkins K,Holme S,Collins P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The supply of phenotyped red blood cells (RBC) for patients with several RBC antibodies presents a difficult task to hospital blood banks and regional blood centers. The aim of this study was to establish a low-cost typing system to allow extensive phenotyping of regular blood donors for clini...

journal_title：Vox sanguinis

authors： Llopis F,Carbonell-Uberos F,Montero MC,Bonanad S,Planelles MD,Plasencia I,Riol C,Planells T,Carrillo C,De Miguel A

更新日期：1999-01-01 00:00:00

abstract：:A competitive inhibition assay for functional fibronectin (Fn), based on ELISA technology, is described. The assay measures Fn's physiologic ability to bind to denatured collagen (gelatin). Affinity-purified Fn inhibits the binding of alkaline phosphatase coupled Fn to gelatin-coated wells of a microtiter plate in a c...

journal_title：Vox sanguinis

authors： Doran JE,Callaway BD,Reese AC,Wynn JJ,Mansberger AR

更新日期：1983-01-01 00:00:00

abstract：:Hepatitis B virus infectivity can be removed from human plasma used to prepare a gamma-globulin product by ion-exchange chromatography with commercially available resins. A pooled human plasma sample free of hepatitis markers was contaminated with 10,000 chimpanzee infectious doses of hepatitis B virus per milliliter ...

journal_title：Vox sanguinis

authors： Zolton RP,Padvelskis JV,Kaplan PM

更新日期：1985-01-01 00:00:00

abstract：:A method is described for the production of mouse monoclonal antibodies to HBsAg. 4 clones produced antibodies directed at the a and one at the d determinant of HBsAg. These antibodies were conjugated to horse radish peroxidase and used in an Elisa for the detection of HBsAg in donated blood. Antibody C10 produced con...

journal_title：Vox sanguinis

authors： Els MC,Govender M,Marimuthu T,Bubb MO,Conradie JD

更新日期：1984-01-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：:A combined immunoassay for the simultaneous detection of antibodies to HIV-1/2 and HTLV-I/II (Bioelisa, Launch Diagnostics) has been evaluated to determine its suitability for routine use in blood screening. 84,222 donations were tested from 76,452 donors. One HIV- and 1 HTLV-1-positive donor were identified. The spec...

journal_title：Vox sanguinis

authors： Flanagan P,McAlpine L,Ramskill SJ,Smith AG,Eglin R,Parry JV,Mortimer PP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Analysis of reports of incidents, involving ABO incompatibility suggests that the main problem is poor interpretation of the pretransfusion bedside compatibility test (PBCT). We studied sources of error as experienced by nurses as to the blood groups of donor blood and of the recipient. MATERI...

journal_title：Vox sanguinis

authors： Dujardin PP,Salmi LR,Ingrand P

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:There are two presumed mechanisms for the pulmonary oedema in transfusion-related acute lung injury (TRALI). One is antibodies to leucocytes while the other is biologically active lipids. We evaluated the vascular injury due to the former. METHODS:The pulmonary vasculature was studied by light microscopy (L...

journal_title：Vox sanguinis

authors： Jensen HM,Galante JM,Kysar PE,Tolstikov VV,Reddy KJ,Holland PV

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Revised Icelandic guidelines proposed a restrictive haemoglobin (Hb) threshold of 70 g/l for red blood cell (RBC) transfusions in general, but 100 g/l for malignancies/bone marrow suppression. Chronic lymphocytic leukaemia (CLL) is frequently complicated by anaemia. The objective was to invest...

journal_title：Vox sanguinis

authors： Thorvaldsson HH,Vidarsson B,Sveinsdottir SV,Olafsson GB,Halldorsdottir AM

更新日期：2019-07-01 00:00:00

abstract：:This report describes a case of persistent polyagglutinability restriced to the red blood cells, and associated with hemolytic anemia in a 20-year-old male. AIME WITH NORMAL INTERVALS. His red blood cells were weakly agglutinated by almost all adult sera. No autoagglutination was noted and the direct antihuman globuli...

journal_title：Vox sanguinis

authors： Graninger W,Rameis H,Fischer K,Poschmann A,Bird GW,Wingham J,Neumann E

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The platelet gel is made by embedding concentrate platelets within a semisolid (gel) network of polymerized fibrin. It is believed that this blood component will be used more and more in the treatment of several clinical conditions and as an adjunctive material in tissue engineering. Several systems are avai...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Borzini P

更新日期：2008-04-01 00:00:00

abstract：:A new red blood cell (RBC) cold autoantibody (anti-Me) is presented which was detected in a patient with autoimmune hemolytic anemia of 'cold type' associated with Waldenström's macroglobulinemia. The autoantibody was of the IgM (Kappa) class, had a moderate titer, and reacted with cord as well as with adult RBC. Its ...

journal_title：Vox sanguinis

authors： Salama A,Pralle H,Mueller-Eckhardt C

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The ultimate goal was to generate an industrial-scale process suitable to produce a high-yield, safe and stable immunoglobulin G (IgG) preparation for intravenous administration, which is ready to use for customer convenience. This new liquid 10% IgG preparation (IGIV 10%) was compared to Gamm...

journal_title：Vox sanguinis

authors： Teschner W,Butterweck HA,Auer W,Muchitsch EM,Weber A,Liu SL,Wah PS,Schwarz HP

更新日期：2007-01-01 00:00:00

abstract：:Platelet concentrates (PCs), stored for 5 days in PL 2209, a new polyvinyl chloride (PVC) storage container plasticised with butyryl trihexyl citrate, were compared with those stored in PL 1240, a PVC platelet container plasticised with triethylhexyl trimellitate. In part 1 of the study, pooled platelet-rich plasma (P...

journal_title：Vox sanguinis

authors： Turner VS,Mitchell SG,Kang SK,Hawker RJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:White blood cell (WBC) fragments may cause human leucocyte antigen (HLA) immunization in recipients. We investigated the occurrence and production of WBC fragments in platelet concentrates (PCs) and plasma units, during storage and filtration, by using real-time polymerase chain reaction (PCR)...

journal_title：Vox sanguinis

authors： Dijkstra-Tiekstra MJ,van der Schoot CE,Pietersz RN,Huijgens PC,van der Meer PF,Reesink HW

更新日期：2004-11-01 00:00:00

abstract：:This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection again...

journal_title：Vox sanguinis

authors： Booth JR,Nuttall PA

更新日期：1978-01-01 00:00:00

abstract：:The panagglutination phenomenon described by Thomsen and Friedenreich (TF) is due to the reaction of naturally occurring TF-antibodies with the carbohydrate group beta-D-Gal-(1-3)-D-GalNAc of desialylated glycophorin A, the major glycoprotein component of the erythrocyte membrane. The specificity of human TF-antibodie...

journal_title：Vox sanguinis

authors： Höppner W,Fischer K,Poschmann A,Paulsen H

更新日期：1985-01-01 00:00:00

abstract：:A family is reported in which the parents' mating is of the 'double back-cross' type with respect to the Sw, Lu and Se genes. The inheritance of these genes in the children shows, with reference to a possible linkage between Sw and the two other loci, four non-recombinants and three recombinants (or vice versa). The i...

journal_title：Vox sanguinis

authors： Metaxas MN,Metaxas-Buehler M

更新日期：1976-01-01 00:00:00

abstract：:We developed a new filter, 'Sepacell-PL', consisting of a blood administration set for the preparation of leukocyte-poor platelet concentrates at the patient's bedside. This filter is packed with 1.8 microns polyester fibers coated with a new polymer, and has a volume of 14 ml. Sepacell-PL removed more than 99% of the...

journal_title：Vox sanguinis

authors： Miyamoto M,Sasakawa S,Ishikawa Y,Ogawa A,Nishimura T,Kuroda T

更新日期：1989-01-01 00:00:00

abstract：:The following substances were tested for their influence on granulocyte function: 8 sera that contained human granulocyte-specific alloantibodies against the antigens NA1, NA2 and NB1, two HLA antisera, and the monoclonal antibodies W6/32 and CLB-FcR-gran 1. The effects examined included spontaneous and directed migra...

journal_title：Vox sanguinis

authors： Bux J,Dickmann JO,Stockert U,Mueller-Eckhardt C

更新日期：1993-01-01 00:00:00

abstract：:Routine screening of blood donations for anti-HIV commenced in the UK during October 1985 and by the end of February 1987 approximately 3.7 million donations had been tested. Seventy-two were confirmed anti-HIV positive, i.e. 0.002%. Of the anti-HIV-positive donors interviewed to date, the majority are young homosexua...

journal_title：Vox sanguinis

authors： Gunson HH,Rawlinson VI

更新日期：1988-01-01 00:00:00

abstract：:Paraformaldehyde-fixed platelets from normal donors were used for detection of antibody to platelet by in vitro sensitization (indirect method) utilizing rabbit anti-human IgG heavy chain specific antibody-coated polyacrylamide gels (Immunobeads). The sensitized platelets formed rosettes with Immunobeads and the posit...

journal_title：Vox sanguinis

authors： Salmassi S,Yokoyama MM,Maples JA,Matsui Y

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The molecular basis of the weak D phenotype has been investigated for many years, and more than 80 different alleles producing weak D phenotypes have been identified. Most alleles producing weak D phenotypes have a single missense mutation in exons corresponding to a transmembrane domain of th...

journal_title：Vox sanguinis

authors： Ogasawara K,Sasaki K,Isa K,Tsuneyama H,Uchikawa M,Satake M,Tadokoro K

更新日期：2016-02-01 00:00:00

abstract：:The domain specificity of anti-factor VIII (FVIII) inhibitor antibodies was determined in assays using FVIII domains generated by thrombin cleavage or expressed as recombinant polypeptides to neutralise the inhibitor. The results revealed the existence of three major types of inhibitors, and various combinations of th...

journal_title：Vox sanguinis

authors： Scandella D

更新日期：1999-01-01 00:00:00

abstract：:As part of a programme to establish a panel of individuals with high titres of anticytomegalovirus (CMV) IgG for the production of CMV Ig, the CMV serostatus of 139 normal blood donors was determined by indirect haemagglutination assay, enzyme immunoassay, and complement fixation. The indirect haemagglutination assay ...

journal_title：Vox sanguinis

authors： Chung A,Chang W,Leung MK,Ofosu FA,Moore BP

更新日期：1984-01-01 00:00:00