Evaluation of a combined HIV-1/2 and HTLV-I/II assay for screening blood donors.

abstract：:We investigated the effects of gravitational force and three different plastic formulations of the storage bags on the quality of stored platelets by measuring the changes in platelet-associated immunoglobulin G (IgG) and two antigenic markers of the third component of human complement (C3), C3d and C3c. Pooled platel...

journal_title：Vox sanguinis

authors： Szymanski IO,Odgren PR,Teno RA,Jacobson MS,Surgenor DM

更新日期：1989-01-01 00:00:00

abstract：:To obtain red cell populations of increasing mean age erythropoiesis was arrested through continuous actinomycin treatment or maintained transfusion polycythemia in mice and rats respectively. The parameters studied included cell indices, enzyme activities and rheological characteristics. Further, the life-span of age...

journal_title：Vox sanguinis

authors： Ganzoni AM,Barras JP,Marti HR

更新日期：1976-01-01 00:00:00

abstract：:Mild as well as strong periodate oxidation of isolated erythrocyte N and M glycoproteins and glycopeptides gave extensive to complete destruction of N-specificities as measured with Vicia graminea extracts and of N- as well as M- activities determined with all but 1 of 8 animal anti-N and 13 anti-M sera. Results with ...

journal_title：Vox sanguinis

authors： Springer GF,Yang HJ

更新日期：1978-01-01 00:00:00

abstract：:Routine screening of blood donations for anti-HIV commenced in the UK during October 1985 and by the end of February 1987 approximately 3.7 million donations had been tested. Seventy-two were confirmed anti-HIV positive, i.e. 0.002%. Of the anti-HIV-positive donors interviewed to date, the majority are young homosexua...

journal_title：Vox sanguinis

authors： Gunson HH,Rawlinson VI

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We identified some fatal cases where massively bleeding patients received inadequate transfusion therapy. The aim of this study was to review and evaluate the transfusion practice in acutely multitransfused patients. MATERIALS AND METHODS:Patients receiving > 10 units of red blood cells (RBC)...

journal_title：Vox sanguinis

authors： Johansson PI,Hansen MB,Sørensen H

更新日期：2005-08-01 00:00:00

abstract：:In this prospective study, 26 consecutive patients being treated for haematological malignancies receiving standard (i.e. non-leucocyte-depleted) blood components were observed for the development of refractoriness to platelet transfusions. One hundred and sixteen of the 266 (44%) platelet transfusions failed to produ...

journal_title：Vox sanguinis

authors： Doughty HA,Murphy MF,Metcalfe P,Rohatiner AZ,Lister TA,Waters AH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inaccuracy of fingerstick haemoglobin compromises donor's health and losses blood donations. We evaluated the benefit of double haemoglobin screening with HemoCue. STUDY DESIGN AND METHODS:Blood donors underwent fingerstick screening by HemoCue and were driven for donation if capillary haemog...

journal_title：Vox sanguinis

authors： Gómez-Simón A,Plaza EM,Torregrosa JM,Ferrer-Marín F,Sánchez-Guiu I,Vicente V,Lozano ML,Rivera J

更新日期：2014-11-01 00:00:00

abstract：:A sensitive ELISA assay for quantifying erythrocyte (E) bound C3 fragments was developed. The assay employs a double-antibody sandwich technique, using polyclonal anti-C3d or anti-C3c antibodies to quantify C3 fragments, expressing C3d and/or C3c epitopes in washed, detergent-solubilized E. The assay detected 50-120 m...

journal_title：Vox sanguinis

authors： Møller Rasmussen J,Jepsen HH,Teisner B,Holmskov-Nielsen U,Rasmussen GG,Svehag SE

更新日期：1989-01-01 00:00:00

abstract：:Inhibitor development represents the main complication in the treatment of haemophilia A. The risk of inhibitor formation is in part genetically determined by the type of the underlying factor VIII gene lesion but environmental factors may also play an important role. Due to the lack of efficiency of factor VIII in th...

journal_title：Vox sanguinis

authors： Brackmann HH,Schwaab R,Effenberger W,Hess L,Hanfland P,Oldenburg J

更新日期：2000-01-01 00:00:00

abstract：:A method of pasteurising a concentrate of factor I (C3b inactivator) prepared from human blood plasma is described. As well as obtaining a high yield of factor I by this virus inactivation procedure it is furthermore possible, by adjustment of the stabiliser concentration, to obtain a very pronounced reduction in the ...

journal_title：Vox sanguinis

authors： Alsøe KO,Kihl J

更新日期：1989-01-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:White blood cell (WBC) fragments may cause human leucocyte antigen (HLA) immunization in recipients. We investigated the occurrence and production of WBC fragments in platelet concentrates (PCs) and plasma units, during storage and filtration, by using real-time polymerase chain reaction (PCR)...

journal_title：Vox sanguinis

authors： Dijkstra-Tiekstra MJ,van der Schoot CE,Pietersz RN,Huijgens PC,van der Meer PF,Reesink HW

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak D phenotypes with very low antigen densities and DEL phenotype may not be detected in RhD typing routine and could be typed as D-negative, leading to D alloimmunization of D-negative recipients. The present study aimed to investigate the presence of RHD-positive genotypes in blood donors ...

journal_title：Vox sanguinis

authors： de Paula Vendrame TA,Prisco Arnoni C,Guilhem Muniz J,de Medeiros Person R,Pereira Cortez AJ,Roche Moreira Latini F,Castilho L

更新日期：2019-11-01 00:00:00

abstract：:Serum IgE was determined by radioimmunoassay in 28 subjects affected by homozygous beta thalassemia (14 males and 14 females, aged 3-19 years, mean age 7 +/- 5.6 years). They were given transfusions with packed red cells and chelant therapy. Blood samples were taken just before a transfusion (basal value) and at 10-da...

journal_title：Vox sanguinis

authors： La Rosa M,Pavone L,Musumeci S,Mollica F,Ronchetti R

更新日期：1983-01-01 00:00:00

abstract：:A Bombay, Le(a-b-) saliva was shown to lack Pneumococcus type XIV activity, an unusual situation, since this sample should be rich in this precursor to the ABO blood group substances. However, the sample was found to contain a new serological specificity, Le-c. It is argued that simple Mendelian inheritance does not o...

journal_title：Vox sanguinis

authors： Savvas RS

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The low prevalence antigen, Be(a), is produced by a complex that also produces weak c, e and f (ce). We report here the molecular basis associated with Be(a) antigen expression. MATERIALS AND METHODS:Peripheral blood samples from four Be(a+) probands were tested. Haemagglutination, gDNA extra...

journal_title：Vox sanguinis

authors： Hue-Roye K,O'Shea K,Gillett R,Wadsworth LD,Hume H,Barnes J,Kinney J,Hodgins K,Fuchisawa A,Lomas-Francis C,Reid M

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:ISO standards for blood bags do not adequately define and control the dimensions of blood bag transfer tubing. This lack of standardization presents potential difficulties when making sterile connections between the wide range of tubing that has evolved in the absence of such standards. We aim...

journal_title：Vox sanguinis

authors： Nightingale MJ,Lees B,Biset R,Mertens W

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Red-blood-cell (RBC) transfusion is associated with lung injury, which is further exacerbated by mechanical ventilation. Manufacturing methods of blood products differ globally and may play a role in the induction of pulmonary cell activation through alteration of the immunomodulatory property...

journal_title：Vox sanguinis

authors： Wirtz MR,Almizraq RJ,Weber NC,Norris PJ,Pandey S,Spinella PC,Muszynski JA,P Acker J,Juffermans NP

更新日期：2020-07-01 00:00:00

abstract：:Platelet concentrates (PCs), stored for 5 days in PL 2209, a new polyvinyl chloride (PVC) storage container plasticised with butyryl trihexyl citrate, were compared with those stored in PL 1240, a PVC platelet container plasticised with triethylhexyl trimellitate. In part 1 of the study, pooled platelet-rich plasma (P...

journal_title：Vox sanguinis

authors： Turner VS,Mitchell SG,Kang SK,Hawker RJ

更新日期：1995-01-01 00:00:00

abstract：:The amount of H antigens on buccal epithelial cells (BEC) of secretors and non-secretors was measured by flow cytometry. H type 1 and H type 2 on BEC were detected with fluorescein-labelled Ulex europaeus lectin, and H type 2 was measured with mouse monoclonal antibody. Between 3.5 and 6 times more H antigen was detec...

journal_title：Vox sanguinis

authors： Rahat A,Stewart J,Blackwell CC,Weir DM

更新日期：1990-01-01 00:00:00

abstract：:An attempt was made to confirm a previously reported association between HLA type B16 and resistance to infection with live attenuated influenza A virus vaccine. No differences were found either in the ability of influenza virus to attach to fractionated white blood cells from HLB B16 subjects compared to cells from s...

journal_title：Vox sanguinis

authors： Mackenzie JS,Wetherall JD,Flower RL,Fimmel PJ,Dawkins RL

更新日期：1979-01-01 00:00:00

abstract：:BACKGROUND  Whole blood (WB) donation encompasses several periods during which some donors faint. Identification of factors associated with fainting during each period should guide intervention strategies. Reducing faint reactions may reduce donor injuries and disability. METHODS  Blood donation was divided into three...

journal_title：Vox sanguinis

authors： Bravo M,Kamel H,Custer B,Tomasulo P

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although transfusion-transmitted infections are rare, non-infectious complications occur relatively frequently. Solvent/detergent-treated fresh-frozen plasma (SD-FFP) has been shown to reduce the frequency of both types of complication, although previous economic evaluations failed to consider...

journal_title：Vox sanguinis

authors： Riedler GF,Haycox AR,Duggan AK,Dakin HA

更新日期：2003-08-01 00:00:00

abstract：:Baboon red cells were treated to reduce oxygen affinity by an osmotic-pulse procedure using dimethyl-sulfoxide. Inositol hexaphosphate (IHP) alone or IHP and adenosine triphosphate (ATP) were incorporated into the red cells in the presence of polyethylene glycol (PEG). The procedure produced variable increases in the ...

journal_title：Vox sanguinis

authors： Franco RS,Weiner M,Wagner K,Martelo OJ,Ragno G,Pivacek LE,Valeri CR

更新日期：1988-01-01 00:00:00

abstract：:Prolonged storage of red blood cells (RBCs) at 4 degrees C results in decreased intracellular ATP levels with diminished posttransfusion survival. Meryman described a preservative medium, exceptional in its capacity to increase these intracellular levels during the first weeks of storage and later in maintaining adequ...

journal_title：Vox sanguinis

authors： Mazor D,Dvilansky A,Meyerstein N

更新日期：1994-01-01 00:00:00

abstract：:We tested serum samples from 11 HIV-seropositive and 32 HIV-seronegative Italian patients with hemophilia A or B for the presence of lymphocytotoxic antibodies (LCTAs). No patients had the acquired immune deficiency syndrome and all had received over many years heat-untreated commercial clotting factors. LCTAs directe...

journal_title：Vox sanguinis

authors： Conte R,Giovanardi L,Tazzari PL,De Rosa V,Rodorigo G,Re MC

更新日期：1988-01-01 00:00:00

abstract：:The modulation of humoral immunity by complement and complement receptors is presented, as well as the importance of the X chromosome in immune response. Gene rearrangement and ontogeny of the immunoglobulin isotypes are discussed with regard to humoral immunodeficiency diseases. ...

journal_title：Vox sanguinis

authors： Wedgwood RJ,Ochs HD

更新日期：1986-01-01 00:00:00

abstract：:The granulocyte immunofluorescence test (GIFT) is valuable for detecting allogeneic and autologous granulocyte antibodies. However, the original tube technique (macro GIFT) requires 50-100 microliters of serum and 10(6) granulocytes with time-consuming washing steps which cause cell loss. We report a modification (mic...

journal_title：Vox sanguinis

authors： Press C,Kline WE,Clay ME,McCullough J

更新日期：1985-01-01 00:00:00

abstract：:If leukocyte- and platelet-poor red cells have been processed and stored in closed bags, their delivery, especially on holidays, will be easy. The modified warm-centrifuge method was applied to a quadruple bag prepared for such purpose. Red cells were processed in the first bag by the centrifugation of whole blood. Th...

journal_title：Vox sanguinis

authors： Shimizu T,Ishikawa Y,Tsurumi H,Hibi S,Takakura R,Morishima Y,Hasegawa I,Goto S

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Currently, plasma fractionation involves multiple processing steps using established methods such as ethanol precipitation and column chromatography. The known limitations associated with conventional purification techniques, combined with strict regulations on safety and high demand for parti...

journal_title：Vox sanguinis

authors： Li G,Stewart R,Conlan B,Gilbert A,Roeth P,Nair H

更新日期：2002-11-01 00:00:00