IgG subclass deficiencies.

Abstract:

:IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infections. Concomitant IgA deficiency is often noted. It is suggested that decreased IgG2 and IgG3 levels in IgA-deficient individuals may increase the risk of recurrent respiratory infection and lung damage. Finally, the efficacy immunoglobulin. prophylaxis in reducing of infection is anecdotally related.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström T

doi

10.1111/j.1423-0410.1986.tb02008.x

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

50-6

eissn

0042-9007

issn

1423-0410

journal_volume

51 Suppl 2

pub_type

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    authors: O'Reilly RJ,Brochstein J,Collins N,Keever C,Kapoor N,Kirkpatrick D,Kernan N,Dupont B,Burns J,Reisner Y

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