Abstract:
:IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infections. Concomitant IgA deficiency is often noted. It is suggested that decreased IgG2 and IgG3 levels in IgA-deficient individuals may increase the risk of recurrent respiratory infection and lung damage. Finally, the efficacy immunoglobulin. prophylaxis in reducing of infection is anecdotally related.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström Tdoi
10.1111/j.1423-0410.1986.tb02008.xsubject
Has Abstractpub_date
1986-01-01 00:00:00pages
50-6eissn
0042-9007issn
1423-0410journal_volume
51 Suppl 2pub_type
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