A multicentre evaluation of a new filtration protocol for leucocyte depletion of high-haematocrit red blood cells collected by an automated blood collection system.

abstract：:A sensitive and specific radioimmunoprecipitation assay was developed for the detection and analysis of anti-HIV antibody response in human sera with the use of 125I-labelled purified HIV proteins with subsequent sodium-dodecylsulfate gel electrophoresis (125I-RIPA). The 125I-RIPA was shown to be as specific but at le...

journal_title：Vox sanguinis

authors： Huisman JG,Winkel IN,Lelie PN,Tersmette M,Goudsmit J,Miedema F

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Individual genomic screening for viruses in blood donations is becoming increasingly pressing as an alternative to pool testing to improve the safety of the blood supply. MATERIALS AND METHODS:To determine the feasibility and, possibly, efficacy of genomic screening for hepatitis C virus (HCV...

journal_title：Vox sanguinis

authors： Petrik J,Hewitt P,Barbara J,Allain J

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Plasma exchange (PE) and immunoadsorption with the Immusorba TR-350 column (IA) are used to remove autoantibodies from plasma in acute neurological autoimmune disorders. The impact of IA on coagulation and on low molecular weight heparin (LMWH) levels in comparison with PE was investigated. P...

journal_title：Vox sanguinis

authors： Koessler J,Kobsar A,Kuhn S,Koessler A,Yilmaz P,Weinig E,Putz E,Boeck M,Klinker E

更新日期：2015-01-01 00:00:00

abstract：:A therapeutic trial of plasma exchange was conducted in an 82-year-old woman with severe cold agglutinin hemolytic anemia, who was unresponsive to conventional treatment. In spite of considerable improvement of pertinent parameters (total IgM, cold agglutinin titer and thermal amplitude) this treatment failed to induc...

journal_title：Vox sanguinis

authors： Rodenhuis S,Maas A,Hazenberg CA,Das PC,Nieweg HO

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to asse...

journal_title：Vox sanguinis

authors： Bugge HF,Karlsen NC,Oydna E,Rake MM,Wexels N,Bendabenda J,Roald B,Heier HE,Chisuwo L,Jourdan PM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study was undertaken to provide denominator data relating to the timing and location of transfusion, to support interpretation of reports of incorrect blood component transfused (IBCT) events to the UK Serious Hazards of Transfusion (SHOT) scheme. MATERIALS AND METHODS:The study was carr...

journal_title：Vox sanguinis

authors： Tinegate HN,Thompson CL,Jones H,Stainsby D

更新日期：2007-10-01 00:00:00

abstract：:Native hemoglobin in the form of stroma-free hemoglobin cannot be used as blood substitute. Hemoglobin has to be modified either molecularly or encapsulated. First generation molecularly modified ultrapure hemoglobins are now in clinical trial--some in Phase III. There are a number of these. Polyhemoglobin is formed b...

journal_title：Vox sanguinis

authors： Chang TM

更新日期：1998-01-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：:A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are ...

journal_title：Vox sanguinis

authors： Mayer S,Hauptmann G,Tongio MM

更新日期：1976-01-01 00:00:00

abstract：:Intra-operative blood cell salvage (IOCS) is mainly avoided in onco surgery due to the suspicion that it could increase metastasis' risk. We simulated IOCS followed by leucodepletion: HCT116 (human colorectal cancer) cells were inoculated into packed red blood cells units, and their distribution was evaluated, step-by...

journal_title：Vox sanguinis

authors： Marraccini C,Merolle L,Berni P,Boito K,Tamagnini I,Kuhn E,Ragazzi M,Baricchi R,Pertinhez TA

更新日期：2017-11-01 00:00:00

abstract：:Blood group antigens reside on cell surface molecules of wide structural and functional diversity. Although all are serologically detectable on red blood cells, most are also expressed in non erythroid tissues, but with a few exceptions their biological role on erythrocytes and tissues often remains elusive. Deficienc...

journal_title：Vox sanguinis

authors： Cartron JP

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Autoantibodies to CD36, a platelet glycoprotein, have been found in patients with thrombotic thrombocytopenic purpura, and in those with lupus-like anticoagulant with thrombotic complications. MATERIALS AND METHODS:Conventional hematologic and laboratory methods were used. The patient was a p...

journal_title：Vox sanguinis

authors： Borzini P,Riva M,Nembri P,Rossi E,Pagliaro P,Vergani P,Greppi P,Tantardini P

更新日期：1997-01-01 00:00:00

abstract：:Experiments have shown that suitably diluted, unpurified IgA paraprotein sera can be substituted for chemically purified IgA proteins in the passive haemagglutination test for the detection of anti-IgA antibodies. The substitution of unpurified IgA paraprotein was made possible by the enhanced serological activity obt...

journal_title：Vox sanguinis

authors： Hunt A,Reed M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Fetal RHD genotyping of cell-free maternal plasma DNA from RhD negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment worksho...

journal_title：Vox sanguinis

authors： Clausen FB,Hellberg Å

更新日期：2020-07-01 00:00:00

abstract：:An attempt was made to confirm a previously reported association between HLA type B16 and resistance to infection with live attenuated influenza A virus vaccine. No differences were found either in the ability of influenza virus to attach to fractionated white blood cells from HLB B16 subjects compared to cells from s...

journal_title：Vox sanguinis

authors： Mackenzie JS,Wetherall JD,Flower RL,Fimmel PJ,Dawkins RL

更新日期：1979-01-01 00:00:00

abstract：:Bivalent 7S subunits were obtained from 7 purified IgM human monoclonal anti-D antibodies with 33-63% of the total protein-retaining functional binding activity. The number of sites per red cell recognized by these subunits ranged between 9,400 and 28,500. The values are taken to indicate that a number of different ep...

journal_title：Vox sanguinis

authors： Hughes-Jones NC,Gorick BD,Beale D

更新日期：1990-01-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

journal_title：Vox sanguinis

authors： Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Our post-thaw cell recovery rates differed substantially in interlaboratory comparisons of identical samples, potentially due to different temperatures during cell staining. MATERIALS AND METHODS:Viable CD34(+) cells and leucocyte (WBC) subtypes were quantified by multiparameter single-platfo...

journal_title：Vox sanguinis

authors： Fritsch G,Frank N,Dmytrus J,Frech C,Pichler H,Witt V,Geyeregger R,Scharner D,Trbojevic D,Zipperer E,Printz D,Worel N

更新日期：2016-08-01 00:00:00

abstract：:Bacterial contamination of platelet concentrates poses a major post-transfusion infectious risk. This study was aimed at evaluating the efficacy of the BacTx(®) assay (Immunetics Inc.) for bacterial detection in leucocyte-reduced buffy coat platelet pools and for its sensitivity in detecting clinical isolates, includi...

journal_title：Vox sanguinis

authors： Ramirez-Arcos S,Kou Y,Perkins H

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Analysis of haemoglobin (Hb) dilution after bleeding is a simple, inexpensive and non-invasive method to estimate blood loss. Blood volume is estimated, taking sex, weight and height into account. The Hb concentration before and after blood loss is analysed and, from the difference, the blood ...

journal_title：Vox sanguinis

authors： Meunier A,Petersson A,Good L,Berlin G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion is associated with a risk of infection and alloimmunization. Pathogen reduction using riboflavin and UV light (Mirasol treatment) inactivates pathogens and leucocytes. With increasing adoption of the technology in clinical use, regulatory agencies have recommended the introduction ...

journal_title：Vox sanguinis

authors： Bakkour S,Chafets DM,Wen L,van der Meer PF,Mundt JM,Marschner S,Goodrich RP,Busch MP,Lee TH

更新日期：2014-11-01 00:00:00

abstract：:Plasmodium falciparum malaria has long been a killer of the young, and has selected for polymorphisms affecting not only erythrocytes, but the immunogenetics of three histocompatibility systems: ABO, human leukocyte antigen (HLA), and CD36. The ABO system is important because the original allele, encoding glycosylatio...

journal_title：Vox sanguinis

authors： Cserti-Gazdewich CM,Mayr WR,Dzik WH

更新日期：2011-01-01 00:00:00

abstract：:Alanine aminotransferase (ALT), gamma-glutamyl-transferase and hepatitis B core antibodies were evaluated as donor markers in a prospective study of 685 open-heart surgery patients. Of these three surrogate markers, only an ALT level greater than or equal to 2 SD above the log mean had a significant association with r...

journal_title：Vox sanguinis

authors： Ebeling F

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anti-CD38 monoclonal antibodies, including daratumumab and isatuximab, often interfere with pretransfusion testing. Dithiothreitol (DTT) treatment of red blood cells (RBCs) negates this interference. However, the optimum DTT concentration and treatment time have not been well defined. Here, we...

journal_title：Vox sanguinis

authors： Furumaki H,Takeshita A,Ohto H,Yamada C,Fujihara H,Ishizuka K,Shibata H,Shinba T,Nemoto N,Ino K,Ozawa A,Watanabe H,Kawabata K,Obata Y

更新日期：2020-12-13 00:00:00

abstract：:Four Kp(a-b-) Japanese sisters, the product of a consanguineous mating, have otherwise normal Kell antigens. Kpc, a 'new' allele of Kpa and Kpb is the most probable background. ...

journal_title：Vox sanguinis

authors： Yamaguchi H,Okubo Y,Seno T,Matsushita K,Daniels GL

更新日期：1979-01-01 00:00:00

abstract：:Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal anaemia with a risk for fetal death and to severe forms of neonatal hyperbilirubinaemia with a risk for kernicterus. Most severe cases are caused by anti-D,...

journal_title：Vox sanguinis

authors： de Haas M,Thurik FF,Koelewijn JM,van der Schoot CE

更新日期：2015-08-01 00:00:00

abstract：:This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection again...

journal_title：Vox sanguinis

authors： Booth JR,Nuttall PA

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Intraoperative autologous blood recovery during radical retro pubic prostatectomy has the potential of contamination with tumour cells. Its safety is proved by similar survival rates between allogeneic and autologous transfusion to oncology patients without standardization. Silencing of the gen...

journal_title：Vox sanguinis

authors： Poli M,Camargo A,Villa L,Moura R,Colella R,Deheinzelin D

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cold-stored platelets may be an alternative to conventional room temperature (RT) storage. However, cold-stored platelets are cleared more rapidly from circulation, reducing their suitability for prophylactic transfusion. To minimise wastage, it may be beneficial to store platelets conventiona...

journal_title：Vox sanguinis

authors： Wood B,Johnson L,Hyland RA,Marks DC

更新日期：2018-04-06 00:00:00

abstract：:During the course of septicaemia, a group A1 patient developed several RBC antigenic modifications. Acquired B antigen, Tk transformation and a partial disappearance of A1 receptors associated with an increase of H reactivity were observed. ...

journal_title：Vox sanguinis

authors： Byrne V,Brown A,Ropars C,Moore BP

更新日期：1979-01-01 00:00:00