Inefficacy of plasma exchange in cold agglutinin hemolytic anemia--a case study.

abstract：BACKGROUND:Immune haemolysis in liver transplant (LT) can occur due to autoantibodies and alloantibodies. The aim of this study was to evaluate the prevalence and risk factors for immune haemolysis in LT. METHODS:A total of 175 consecutive patients were included. Multiorgan recipients were excluded. Samples, from befo...

journal_title：Vox sanguinis

authors： Brunetta DM,de Barros Carlos LM,Da Silva VFP,de Oliveira Alves TM,Macedo ÊS,Coelho GR,Vasconcelos JBM,De Francesco Daher E,Garcia JHP

更新日期：2020-01-01 00:00:00

abstract：:A large 81 member, four-generation black family with hereditary angioedema is reported with regards to its clinical course and the association with the histocompatibility system. No mortality was seen related directly to the disease. Assuming that this trait is autosomal dominant it appeared to have no linkage with th...

journal_title：Vox sanguinis

authors： Blumenthal MN,Dalmasso AP,Roitman B,Kelly J,Noreen H,Emmy L,Mendell NR,Yunis EJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Currently, plasma fractionation involves multiple processing steps using established methods such as ethanol precipitation and column chromatography. The known limitations associated with conventional purification techniques, combined with strict regulations on safety and high demand for parti...

journal_title：Vox sanguinis

authors： Li G,Stewart R,Conlan B,Gilbert A,Roeth P,Nair H

更新日期：2002-11-01 00:00:00

abstract：:In recent years the development of recombinant DNA and sequencing techniques has led to a greatly increased understanding of the genetic complexity, structure and function of the human major histocompatibility complex. This system may be subdivided into the "classical' HLA (human leukocyte antigen) class I and II tran...

journal_title：Vox sanguinis

authors： Howell WM,Navarrete C

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of the study was to evaluate lyophilized monoclonal IgM anti-A and anti-B preparations for use as international standards (IS) to specify recommended minimum potencies of anti-A and anti-B blood grouping reagents in tube tests. MATERIALS AND METHODS:The candidate IS for minimum potenc...

journal_title：Vox sanguinis

authors： Thorpe SJ,Fox B,Heath AB,Scott M,de Haas M,Kochman S,Padilla A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The clinical significance of immune thrombocytopenia (ITP) is mainly reflected by bleeding and/or bleeding risks, which, in some cases, cannot be adequately controlled by standard therapy. Tranexamic acid (TA) is increasingly used in preventing and reducing bleeding in several medical settings...

journal_title：Vox sanguinis

authors： Mayer B,Salama A

更新日期：2017-11-01 00:00:00

abstract：:A model of the Rh blood group system is proposed which is based on discontinuous gene structure. The R29 control subregion consists of a single exon flanked by introns. Following the R29 subregion, the R1 subregion exists as seven exon structures which alternate with introns. The expression of each exon is controlled ...

journal_title：Vox sanguinis

authors： Giorno R

更新日期：1981-01-01 00:00:00

abstract：INTRODUCTION:Bleeding is increasingly considered an important end point in clinical platelet transfusion studies. Accurate recording and adjudication into well-defined bleeding grades, however, remains a major challenge. METHODS:We developed a computer algorithm for automatic adjudication. The algorithm's results were...

journal_title：Vox sanguinis

authors： Middelburg RA,Ypma PF,van der Meer PF,van Wordragen-Vlaswinkel RJ,Eissen O,Kerkhoffs JL

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:During the past 10 years several DNA-typing methods have been developed to complement routine serological typing for determination of polymorphisms in the ABO, RH, KEL, JK and FY blood group genes. However, the molecular basis of blood groups can differ widely between ethnic groups. The purpos...

journal_title：Vox sanguinis

authors： Irshaid NM,Ramadan S,Wester ES,Olausson P,Hellberg A,Merza JY,Olsson ML

更新日期：2002-07-01 00:00:00

abstract：:Separable anti-T and anti-Tk lectins can be extracted from the seeds of Vicia hyrcanica. The anti-T lectin is similar to that of the peanut, Arachis hypogaea; the anti-Tk lectin compares favourably with that of Griffonia simplicifolia II. ...

journal_title：Vox sanguinis

authors： Liew YW,Bird GW

更新日期：1988-01-01 00:00:00

abstract：:An antibody to a high frequency antigen, made in a WES+ Black antenatal patient (Wash.), failed to react with the red cells of a presumed WES+ homozygote and is, therefore, probably antithetical to anti-WES. Like anti-WES, it reacted with papain, ficin, trypsin or neuraminidase treated cells but not with alpha-chymotr...

journal_title：Vox sanguinis

authors： Daniels GL,Green CA,Darr FW,Anderson H,Sistonen P

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. MATERIALS AND METHODS:The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelet...

journal_title：Vox sanguinis

authors： Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：:beta 2-Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions beta 2-microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the c...

journal_title：Vox sanguinis

authors： Bernier GM

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to asse...

journal_title：Vox sanguinis

authors： Bugge HF,Karlsen NC,Oydna E,Rake MM,Wexels N,Bendabenda J,Roald B,Heier HE,Chisuwo L,Jourdan PM

更新日期：2013-01-01 00:00:00

abstract：:The classic enzyme-linked antiglobulin test (ELAT) used to detect and quantify the amount of IgG antibodies on red blood cells (RBC) is sensitive to hemolysis and erythrocyte enzymatic activities. We describe a new ELAT by using glucose oxidase (GO) linked to antihuman IgG. The optical density base line of GO-ELAT, al...

journal_title：Vox sanguinis

authors： Rigal D,Monestier M,Lafont S,Raffin T,Got A,Meyer F,Jouvenceaux A

更新日期：1984-01-01 00:00:00

abstract：:We report a preliminary study on whether syphilis serology might be reactive in some blood donors at risk for human immunodeficiency virus (HIV) infection. We retrospectively analyzed voluntary blood donations with reactive Treponema pallidum antibody (TPA) tests according to the type of donation, the presence of othe...

journal_title：Vox sanguinis

authors： Ramsey G,Soltis F,Bowman R,McNamee J,Hahn LF,Dixon BW

更新日期：1991-01-01 00:00:00

abstract：:The mechanism of CD4+ lymphocyte depletion, which is the main immunological feature in HIV-infected patients, is unclear. We investigated whether gp120-immunoglobulin-complement complexes on the surface of CD4+ cells might be involved in the elimination of CD4+ lymphocytes. The results obtained in 63 HIV-infected pati...

journal_title：Vox sanguinis

authors： Daniel V,Süsal C,Prodeus AP,Weimer R,Zimmermann R,Huth-Kühne A,Opelz G

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although transfusion-transmitted infections are rare, non-infectious complications occur relatively frequently. Solvent/detergent-treated fresh-frozen plasma (SD-FFP) has been shown to reduce the frequency of both types of complication, although previous economic evaluations failed to consider...

journal_title：Vox sanguinis

authors： Riedler GF,Haycox AR,Duggan AK,Dakin HA

更新日期：2003-08-01 00:00:00

abstract：:An IgM kappa cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)-treated RBC. It resembled anti-Me cold agglutinin in these serological findings. However, the activity of this agglutinin against RBC was markedly de...

journal_title：Vox sanguinis

authors： Kajii E,Ikemoto S

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Glycocalicin (GC) is a proteolytic fragment of GpIb and can conveniently be measured in supernatants of platelet concentrates (PCs) by means of a sandwich ELISA. Because of the convenience of the assay and easy sample storage, we tested its suitability as a sensitive platelet activation parame...

journal_title：Vox sanguinis

authors： Kostelijk EH,Folman CC,Gouwerok CW,Kramer CM,Verhoeven AJ,de Korte D

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:To determine whether the attitudes, beliefs and motivations of blood donors evolve over time. MATERIALS AND METHODS:Using questionnaires a 7-year longitudinal study of a cohort of 126 donors was performed to gather their sociodemographic characteristics and their attitudes, beliefs and motivations relating ...

journal_title：Vox sanguinis

authors： Fernández-Montoya A,López-Berrio A,Luna del Castillo JD

更新日期：1998-01-01 00:00:00

abstract：:Experiments have shown that suitably diluted, unpurified IgA paraprotein sera can be substituted for chemically purified IgA proteins in the passive haemagglutination test for the detection of anti-IgA antibodies. The substitution of unpurified IgA paraprotein was made possible by the enhanced serological activity obt...

journal_title：Vox sanguinis

authors： Hunt A,Reed M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The results of quality monitoring leucocyte counts were analysed nationally for the first 2 years of universal leucocyte depletion (LD), spanning the time-period before and after standardization of the counting and LD methods. The objectives were twofold: first to determine whether the impleme...

journal_title：Vox sanguinis

authors： Beckman N,Cardigan R,Wallington T,Williamson LM

更新日期：2002-08-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：:Articles on the appropriateness of intention-to-treat (ITT) vs. as-treated (AT) analyses of randomized controlled trials (RCTs) have highlighted issues relevant to drug trials, such as approaches suitable for 'explanatory' vs. 'pragmatic' RCTs. These considerations are less relevant to transfusion medicine RCTs, espec...

journal_title：Vox sanguinis

authors： Vamvakas EC

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. METHODS:Donation (n = 180)...

journal_title：Vox sanguinis

authors： Feys HB,Coene J,Devloo R,Van Aelst B,Pottel H,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：:Hepatitis E virus (HEV)-positive plasma donations, identified by a plasma mini-pool screening approach, were analysed using serological methods for the presence of anti-HEV IgM and IgG. Avidity testing was performed on the IgG-reactive donations. Anti-HEV IgG with high avidity was observed in two donors together with ...

journal_title：Vox sanguinis

authors： Baylis SA,Crossan C,Corman VM,Blümel J,Scobie L,Dalton HR

更新日期：2015-11-01 00:00:00

abstract：:The factors that impact upon successful bone marrow transplantation leading to immunologic reconstitution in severe combined immune deficiency (SCID). Wiskott-Aldrich syndrome, and in other lethal congenital immunodeficiencies are reviewed. Evidence is presented that graft-versus-host disease (GVHD) can be abrogated b...

journal_title：Vox sanguinis

authors： O'Reilly RJ,Brochstein J,Collins N,Keever C,Kapoor N,Kirkpatrick D,Kernan N,Dupont B,Burns J,Reisner Y

更新日期：1986-01-01 00:00:00

abstract：:Human IgG separated by Cohn fractionation showed variability in the content of aggregates, plasminogen and anticomplement activity. The plasminogen was removed or markedly reduced by affinity chromatography on Sepharose-lysine. Anticomplement activity was reduced by chromatography of Cohn fraction II on DEAE-cellulose...

journal_title：Vox sanguinis

authors： Habeeb AF,Francis RD

更新日期：1977-01-01 00:00:00

abstract：:The granulocyte immunofluorescence test (GIFT) is valuable for detecting allogeneic and autologous granulocyte antibodies. However, the original tube technique (macro GIFT) requires 50-100 microliters of serum and 10(6) granulocytes with time-consuming washing steps which cause cell loss. We report a modification (mic...

journal_title：Vox sanguinis

authors： Press C,Kline WE,Clay ME,McCullough J

更新日期：1985-01-01 00:00:00