A 'new' Cromer-related high frequency antigen probably antithetical to WES.

Abstract:

:An antibody to a high frequency antigen, made in a WES+ Black antenatal patient (Wash.), failed to react with the red cells of a presumed WES+ homozygote and is, therefore, probably antithetical to anti-WES. Like anti-WES, it reacted with papain, ficin, trypsin or neuraminidase treated cells but not with alpha-chymotrypsin or pronase treated cells and was specifically inhibited by concentrated serum. It also reacted more strongly in titration with WES- cells than with WES+ cells. The antibody is Cromer-related as it failed to react with Inab phenotype (IFC-) cells and reacted only weakly with Dr(a-) cells. Wash. cells and those of the other possible WES+ homozygote are Cr(a+) Tc(a+b-c-) Dr(a+) IFC+ but reacted only very weakly with anti-Esa.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Daniels GL,Green CA,Darr FW,Anderson H,Sistonen P

doi

10.1111/j.1423-0410.1987.tb05073.x

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

235-8

issue

4

eissn

0042-9007

issn

1423-0410

journal_volume

53

pub_type

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