Study of coagulation function in thawed apheresis plasma for photochemical treatment by amotosalen and UVA.

Abstract:

BACKGROUND AND OBJECTIVES:Photochemical treatment (PCT) based on amotosalen and ultraviolet A light (UVA) demonstrated a wide range of pathogen inactivation. However, coagulation proteins are affected by this treatment. The aim of this study was to evaluate the coagulation parameters in apheresis plasma units after thawing and processing by PCT. MATERIALS AND METHODS:Thirty apheresis plasma units were rapidly frozen at

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

de Valensart N,Rapaille A,Goossenaerts E,Sondag-Thull D,Deneys V

doi

10.1111/j.1423-0410.2008.001147.x

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

213-8

issue

3

eissn

0042-9007

issn

1423-0410

pii

VOX1147

journal_volume

96

pub_type

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