Preparation of human immunoglobulin free of plasmin and anticomplement activities.

abstract：BACKGROUND:Whole blood is stored at room temperature (RT) until processing into components. After separation and filtration, the RCC has to be cooled from RT to +2 - 6°C. Different start times of the cooling process and different cooling rates can be encountered in daily routine. The effect of these parameters of the i...

journal_title：Vox sanguinis

authors： Bontekoe IJ,van der Meer PF,de Korte D

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The rationale for using topical platelet gel therapy is to provide the healing tissues with concentrated platelet-derived factors. Several systems are available to prepare platelet-rich plasma (PRP) and from these, the platelet gel. These systems produce two- to six-fold platelet and growth factor-enriched c...

journal_title：Vox sanguinis

authors： Mazzucco L,Balbo V,Cattana E,Guaschino R,Borzini P

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Reconstitution of hematopoiesis by means of peripheral blood stem cells is a valid alternative to autologous bone marrow transplantation. The aim of this investigation was to increase the efficiency of collection of circulating blood progenitor cells and to obtain a purer product for transplant. METHODS:We ...

journal_title：Vox sanguinis

authors： Menichella G,Lai M,Pierelli L,Vittori M,Serafini R,Ciarli M,Foddai ML,Salerno G,Sica S,Scambia G,Leone G,Bizzi B

更新日期：1997-01-01 00:00:00

abstract：:Radioimmunoassays were prepared using two anti-A and one anti-B reagents. The specificity of the procedures was assessed with 13 artificial antigens. The amounts of A and B natural antigens in saliva of ABH secretors of known Lewis phenotype were measured with these assays. The results confirmed that the average amoun...

journal_title：Vox sanguinis

authors： Le Pendu J,Lemieux RU,Dalix AM,Lambert F,Oriol R

更新日期：1983-01-01 00:00:00

abstract：:The following substances were tested for their influence on granulocyte function: 8 sera that contained human granulocyte-specific alloantibodies against the antigens NA1, NA2 and NB1, two HLA antisera, and the monoclonal antibodies W6/32 and CLB-FcR-gran 1. The effects examined included spontaneous and directed migra...

journal_title：Vox sanguinis

authors： Bux J,Dickmann JO,Stockert U,Mueller-Eckhardt C

更新日期：1993-01-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Immune haemolysis in liver transplant (LT) can occur due to autoantibodies and alloantibodies. The aim of this study was to evaluate the prevalence and risk factors for immune haemolysis in LT. METHODS:A total of 175 consecutive patients were included. Multiorgan recipients were excluded. Samples, from befo...

journal_title：Vox sanguinis

authors： Brunetta DM,de Barros Carlos LM,Da Silva VFP,de Oliveira Alves TM,Macedo ÊS,Coelho GR,Vasconcelos JBM,De Francesco Daher E,Garcia JHP

更新日期：2020-01-01 00:00:00

abstract：:Blood transfusion practices have evolved empirically, with few or no research data supporting them. In the past several decades, fuelled by fears of infection and reports of mistakes, patients have increasingly demanded their rights to choice, both in the components given to them as well as to refuse to receive these ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：2007-02-01 00:00:00

abstract：:Ocular chronic GVHD is efficaciously treated with autologous platelet-derived eye drops. We investigated the cytokine content of eye drops produced using a non-gelified lysate obtained from autologous platelet-rich plasma in six patients with ocular GVHD. In both the responding (n = 4) and the resistant (n = 2) patien...

journal_title：Vox sanguinis

authors： Valentini CG,Nuzzolo ER,Orlando N,Metafuni E,Bianchi M,Chiusolo P,Zini G,Teofili L

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this review was to summarize the properties of the commonly available resuscitation fluids and highlight where knowledge of the characteristics of individual fluids might guide their use in clinical practice. Some of the current controversies surrounding resuscitation fluids are als...

journal_title：Vox sanguinis

authors： Grocott MP,Hamilton MA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：:Tissue oxygen delivery depends on red blood cell (RBC) content and RBC flow regulation in the microcirculation. The important role of the RBC in tissue oxygenation is clear from anaemia and the use of RBC transfusion which has saved many lives. Whether RBC transfusion actually restores tissue oxygenation is difficult ...

journal_title：Vox sanguinis

authors： Raat NJ,Ince C

更新日期：2007-07-01 00:00:00

abstract：:Direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (ITP) revealed positive staining on the surface of platelets for both immunoglobulins (Igs) and human B1C globulin in 9 specimens, for only Igs in 1 specimen and for human B1C alone in 5 specime...

journal_title：Vox sanguinis

authors： Boonpucknavig S,Vuttivirojana O,Srichaikul T

更新日期：1979-01-01 00:00:00

abstract：:Although we still do not know enough about the influence of anaemia and transfusion on outcomes for the surgical patient, it is possible to develop a general consensus about many aspects of management. A quality programme to improve consistency of practice in these consensus areas is feasible. (Table 6) This should be...

journal_title：Vox sanguinis

authors： McClelland B

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:Positive direct antiglobulin tests (DAT) occur occasionally, without obvious cause, among normal blood donors. This is sometimes associated with a false-positive serologic test for syphilis. Positive DATs due to antiphospholipid antibodies (APAbs) are well documented in the antiphospholipid syndrome with sys...

journal_title：Vox sanguinis

authors： Win N,Islam SI,Peterkin MA,Walker ID

更新日期：1997-01-01 00:00:00

abstract：:The presence of the glycoproteins haptoglobin and hemopexin in human plasma albumin (HPA) solutions were demonstrated to be responsible for the formation of polymers and aggregates during heat treatment for 10 h at 60 degrees C. Apart from haptoglobin and hemopexin three other contaminating proteins were identified as...

journal_title：Vox sanguinis

authors： Jensen LB,Dam J,Teisner B

更新日期：1994-01-01 00:00:00

abstract：:Two batches of heat-treated factor VIII concentrate were found to contain anti-HIV-positive plasma donations. The batches were dry-heat-treated at 68 degrees C for 2 and 24 h, respectively. No HIV seroconversions occurred in 13 susceptible haemophiliacs receiving a total of 540 bottles of these factor VIII preparation...

journal_title：Vox sanguinis

authors： Cuthbert RJ,Ludlam CA,Brookes E,McClelland DB

更新日期：1988-01-01 00:00:00

abstract：:The interaction of temperature and pH in biological systems comprises two components. Temperature change may perturb the pH of solutions, and it may change the pKa of some ionizable groups that are involved in enzyme catalysis. The pH optima of single reactions and whole pathways are therefore temperature sensitive. T...

journal_title：Vox sanguinis

authors： Guppy M,Attwood PV,Hansen IA,Sabaratnam R,Frisina J,Whisson ME

更新日期：1992-01-01 00:00:00

abstract：:The successful cloning of a non-structural antigen from the genome of what is now designated as the 'hepatitis C virus' (HCV) has transformed an erstwhile diagnosis of exclusion for non-A, non-B hepatitis (NANBH). The assay has been validated against panels of known infectivity for NANBH and sera from haemophiliac pat...

journal_title：Vox sanguinis

authors： Barbara JA,Contreras M

更新日期：1991-01-01 00:00:00

abstract：:Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...

journal_title：Vox sanguinis

authors： Yoshida H,Ito K,Emi N,Kanzaki H,Matsuura S

更新日期：1984-01-01 00:00:00

abstract：:The use of granulocyte transfusions in profoundly neutropenic patients has increased markedly in recent years. Whenever a pulmonary infiltrate develops during the course of these transfusions, the question arises as to what role the transfusions are playing and whether the transfusions should be discontinued to preven...

journal_title：Vox sanguinis

authors： Karp DD,Ervin TJ,Tuttle S,Gorgone BC,Lavin P,Yunis EJ

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:There is increasing interest in the development of rapid and reliable techniques for human platelet alloantigen (HPA) typing. This study investigates the reliability of flow cytometry for large-scale immunophenotyping of platelet alloantigens. MATERIALS AND METHODS:We used flow cytometry and ...

journal_title：Vox sanguinis

authors： Tazzari PL,Cirillo D,Bontadini A,Ricci F,Masi R,Conte R

更新日期：1998-01-01 00:00:00

abstract：:Three 'A1 weak B' blood groups found in two generations of a Romanian family were studied with quantitative and thermodynamic assays in order to determine if they derive from 'A1Bx' or from 'cis AB' genotypes, what cannot be achieved by the genetics. ...

journal_title：Vox sanguinis

authors： Lopez M,Danielescu M,Liberge G,Salmon C

更新日期：1975-01-01 00:00:00

abstract：:The decline in the incidence of TAH from 1985-1990 was considerable and based on a variety of interventions that led to increasingly intensive scrutiny of potential donors. The decline in incidence observed since 1990, and particularly since 1992, has been truly extraordinary and based principally on the introduction ...

journal_title：Vox sanguinis

authors： Alter HJ

更新日期：1994-01-01 00:00:00

abstract：:The modulation of humoral immunity by complement and complement receptors is presented, as well as the importance of the X chromosome in immune response. Gene rearrangement and ontogeny of the immunoglobulin isotypes are discussed with regard to humoral immunodeficiency diseases. ...

journal_title：Vox sanguinis

authors： Wedgwood RJ,Ochs HD

更新日期：1986-01-01 00:00:00

abstract：:Pre- and posttransfusion antibody titers were performed on 6 patients with anti-Sda transfused with incompatible blood. In 3 of these patients a significant rise in IgG antibody titer was found. The data suggest that in occasional patients the Sda antigen does evoke a secondary immune response. We evaluated 245 pregna...

journal_title：Vox sanguinis

authors： Spitalnik S,Cox MT,Spennacchio J,Guenther R,Blumberg N

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Intraoperative autologous blood recovery during radical retro pubic prostatectomy has the potential of contamination with tumour cells. Its safety is proved by similar survival rates between allogeneic and autologous transfusion to oncology patients without standardization. Silencing of the gen...

journal_title：Vox sanguinis

authors： Poli M,Camargo A,Villa L,Moura R,Colella R,Deheinzelin D

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The study was designed to evaluate whether volume replacement following blood donation can prevent arterial hypotension in autologous blood donors with cardiovascular disease. MATERIALS AND METHODS:One hundred nineteen autologous blood donors with known cardiovascular disease were randomly al...

journal_title：Vox sanguinis

authors： Kasper SM,Dahlmann H,Mellinghoff H,Ellering J,Baumann M,Buzello W

更新日期：1998-01-01 00:00:00

abstract：:The second International Society of Blood Transfusion and International Council for Standardization in Haematology workshop on molecular blood group genotyping was held in 2006. Forty-one laboratories participated. Six samples were distributed: two representing DNA from transfusion-dependent patients for testing for a...

journal_title：Vox sanguinis

authors： Daniels G,van der Schoot CE,Olsson ML

更新日期：2007-07-01 00:00:00

abstract：:The proteins and sodium in human source blood plasma are segregated and concentrated on freezing, particularly in plasma that is frozen slowly in a large container. The temperature and the concentration gradients at the freezing front induce a convection in the liquid phase and thus play the primary role in the segreg...

journal_title：Vox sanguinis

authors： Chang CE

更新日期：1983-01-01 00:00:00