Transfusion transmitted hepatitis C and non-A, non-B, non-C.

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：:The effect on cryoprecipitate factor VIII recovery of three imortant variables has been investigated. The design of the study was such as to eliminate, for the purpose of internal comparisons, spurious effects such as those due to the variation in factor VIII levels in donor plasma. The choice of anticoagulant was sho...

journal_title：Vox sanguinis

authors： Wensley RT,Snape TJ

更新日期：1980-01-01 00:00:00

abstract：:The second example of anti-F1 cold agglutinins recognizing a developmentally regulated antigen like I is described. The antibody occurred transiently and simultaneously together with an anti-I cold agglutinin. Although anti-F1 and anti-I specificities are entirely different, the data on the biochemistry of F1 and I an...

journal_title：Vox sanguinis

authors： Roelcke D,Weber MT

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Factor VIII (FVIII) levels are used as a quality marker of fresh-frozen plasma (FFP); however, other clotting factors are not routinely measured. METHODS:We assessed additional haemostatic parameters and the dynamics of coagulation using Thrombelastography (TEG) and a thrombin generation test (TGT). FFP was...

journal_title：Vox sanguinis

authors： Lawrie AS,Cardigan RA,Williamson LM,Machin SJ,Mackie IJ

更新日期：2008-05-01 00:00:00

abstract：:We report the development of a semi-continuous method for preparation of factor IX complex from human plasma using ion exchange resins. Traditionally, stirred batch adsorption has been used due to the high pressure drops and low flow rates associated with soft gels in packed columns. Batch methods, however, typically ...

journal_title：Vox sanguinis

authors： Tharakan JP,Gee DM,Clark DB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Serratia marcescens is a gram-negative bacterium that has been implicated in adverse transfusion reactions associated with contaminated platelet concentrates. The aim of this study was to investigate whether the ability of S. marcescens to form surface-attached aggregates (biofilms) could acco...

journal_title：Vox sanguinis

authors： Greco-Stewart VS,Brown EE,Parr C,Kalab M,Jacobs MR,Yomtovian RA,Ramírez-Arcos SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The study was designed to evaluate whether volume replacement following blood donation can prevent arterial hypotension in autologous blood donors with cardiovascular disease. MATERIALS AND METHODS:One hundred nineteen autologous blood donors with known cardiovascular disease were randomly al...

journal_title：Vox sanguinis

authors： Kasper SM,Dahlmann H,Mellinghoff H,Ellering J,Baumann M,Buzello W

更新日期：1998-01-01 00:00:00

abstract：:A major drawback in the use of platelet transfusions is the development of platelet refractoriness that is usually caused by alloimmunization provoked by leukocytes present in the blood products. We evaluated the development of alloimmunization both by serological demonstration of HLA antibodies and by clinical demons...

journal_title：Vox sanguinis

authors： Saarinen UM,Koskimies S,Myllylä G

更新日期：1993-01-01 00:00:00

abstract：:A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were ...

journal_title：Vox sanguinis

authors： Hunt AF,Jones MT,Howkins GJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The last two decades have seen major developments in genotyping assays to facilitate the procurement of red blood cell units to alloimmunized patients. To make genotyping faster, simpler and less costly, a nanotechnology approach based on metal/silica fluorescent nanoparticles and a polymer-ba...

journal_title：Vox sanguinis

authors： Brouard D,Ratelle O,Perreault J,Boudreau D,St-Louis M

更新日期：2015-02-01 00:00:00

abstract：:There is almost general agreement that removal of leukocytes from blood components reduces the incidence of HLA-antibody formation and refractoriness to random platelet transfusions. Recently filters have become available, which are able to reduce leukocyte contamination in platelet suspensions with acceptable platele...

journal_title：Vox sanguinis

authors： Novotny VM,van Doorn R,Rozier Y,D'Amaro J,Harvey MS,Brand A

更新日期：1992-01-01 00:00:00

abstract：:2 patients on the drug azapropazone developed positive antiglobulin tests. Their sera were each found to contain two distinct antibodies. One was an IgG antibody, probably a drug-dependent autoantibody of the alpha-methyldopa type, but could have been related to the disease. The other was certainly a drug-dependent an...

journal_title：Vox sanguinis

authors： Bird GW,Wingham J,Babb RG,Bacon P,Wood D

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:While blood is flowing within a transfusion-warming device, the blood temperature is usually less than that applied externally. If the flow is temporarily stopped, the temperature can rise above 37 degrees C in some warming devices. We sought to determine whether temperatures near 45 degrees C...

journal_title：Vox sanguinis

authors： Eastlund T,Van Duren A,Clay ME

更新日期：1999-01-01 00:00:00

abstract：:Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...

journal_title：Vox sanguinis

authors： Yoshida H,Ito K,Emi N,Kanzaki H,Matsuura S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Human monoclonal antibodies have been produced against various Rh antigens. We report here the production of another one against Rh C and the first such antibody against Rh CW. MATERIALS AND METHODS:Two heterohybridomas secreting IgG human monoclonal antibodies against Rh CW and Rh C (MS-353 ...

journal_title：Vox sanguinis

authors： Thorpe SJ,Boult CE,Thompson KM

更新日期：1997-01-01 00:00:00

abstract：:Bivalent 7S subunits were obtained from 7 purified IgM human monoclonal anti-D antibodies with 33-63% of the total protein-retaining functional binding activity. The number of sites per red cell recognized by these subunits ranged between 9,400 and 28,500. The values are taken to indicate that a number of different ep...

journal_title：Vox sanguinis

authors： Hughes-Jones NC,Gorick BD,Beale D

更新日期：1990-01-01 00:00:00

abstract：:A sandwich-type solid phase radioimmunoassay, FRC-RIA (Finnish Red Cross-RIA) for hepatitis B surface antigen (HBsAg) is described. Polystyrene test tubes coated with sheep anti-HBs gamma-globulin serve as the solid phase. The technique is specific and has a sensitivity of about 1 ng/ml for the subtypes ad and ay of H...

journal_title：Vox sanguinis

authors： Koistinen V

更新日期：1978-01-01 00:00:00

abstract：:Peripheral blood stem cell cryopreservation is associated with cell damage and decreased viability. We evaluated the impact of up to 10 years of cryopreservation (5% DMSO) on viability of CD34(+) cells utilizing graft samples of consecutive patients (2002-2012) with different malignancies who underwent stem cell colle...

journal_title：Vox sanguinis

authors： Abbruzzese L,Agostini F,Durante C,Toffola RT,Rupolo M,Rossi FM,Lleshi A,Zanolin S,Michieli M,Mazzucato M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The low-prevalence Rh antigen, JAL, was named after the index case, Mr. J. Allen. Based on reactivity of seven multi-specific sera with his RBCs, it was apparent that they express at least one additional low-prevalence antigen. The purpose of this study was to investigate the other low-prevalence antigen(s) ...

journal_title：Vox sanguinis

authors： Hue-Roye K,Reid ME,Westhoff CM,Lomas-Francis C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A large number of European blood centres, including our own, use the buffy-coat method for platelet production. In this article we describe a previously unnoticed phenomenon shown by a proportion of buffy-coats, which display an unusually bright cherry colour and low platelet counts. MATERIAL...

journal_title：Vox sanguinis

authors： Rebulla P,Smacchia C,Greppi N,Porretti L,Lopa R,Cernuschi M,Sirchia G

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：:Serum IgE was determined by radioimmunoassay in 28 subjects affected by homozygous beta thalassemia (14 males and 14 females, aged 3-19 years, mean age 7 +/- 5.6 years). They were given transfusions with packed red cells and chelant therapy. Blood samples were taken just before a transfusion (basal value) and at 10-da...

journal_title：Vox sanguinis

authors： La Rosa M,Pavone L,Musumeci S,Mollica F,Ronchetti R

更新日期：1983-01-01 00:00:00

abstract：:Metabolic properties of standard gamma globulin (St-GG) and of several gamma globulin (GG) preparations for intravenous use were analyzed in radioactive tracer studies. The in vivo behaviour of St-GG was investigated in 16 probands and found to be comparable to that of normal IgG. The kinetics of the resorption of St-...

journal_title：Vox sanguinis

authors： Morell A,Schürch B,Ryser D,Hofer F,Skvaril F,Barandun S

更新日期：1980-01-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

journal_title：Vox sanguinis

authors： Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

更新日期：2008-01-01 00:00:00

abstract：:A Bombay, Le(a-b-) saliva was shown to lack Pneumococcus type XIV activity, an unusual situation, since this sample should be rich in this precursor to the ABO blood group substances. However, the sample was found to contain a new serological specificity, Le-c. It is argued that simple Mendelian inheritance does not o...

journal_title：Vox sanguinis

authors： Savvas RS

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The occurrence of thromboembolic events (TEEs) with intravenous immunoglobulin lots (IVIGs) raised the question of the causative agent for these adverse events. We investigated the predominant plasma proteases in 19 IVIG lots from five manufacturers including three lots associated with adverse...

journal_title：Vox sanguinis

authors： Etscheid M,Breitner-Ruddock S,Gross S,Hunfeld A,Seitz R,Dodt J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Immune haemolysis in liver transplant (LT) can occur due to autoantibodies and alloantibodies. The aim of this study was to evaluate the prevalence and risk factors for immune haemolysis in LT. METHODS:A total of 175 consecutive patients were included. Multiorgan recipients were excluded. Samples, from befo...

journal_title：Vox sanguinis

authors： Brunetta DM,de Barros Carlos LM,Da Silva VFP,de Oliveira Alves TM,Macedo ÊS,Coelho GR,Vasconcelos JBM,De Francesco Daher E,Garcia JHP

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：:The etiologic agent for acquired immune deficiency syndrome (AIDS) has been identified as human T lymphotropic virus type III (HTLV-III). Its distinguishing characteristics and putative receptor, the T4 molecule, are discussed. The Western Blot method has been applied to assess the presence of antibody to HTLV-III in ...

journal_title：Vox sanguinis

authors： Pahwa S

更新日期：1986-01-01 00:00:00

abstract：:A non-blow-molded LE-2 polyolefin (PO) container was developed to store single-donor apheresis platelet concentrates (PCs) processed by the Haemonetics Plasma Collecting System (PCS) at 22 degrees C for over 1 day. We molded PO containers with heat-sealing of light-weight polymer alloy films with a thickness of 0.25 m...

journal_title：Vox sanguinis

authors： Shimizu T,Kouketsu K,Kamiya T,Futagawa H,Hirose S

更新日期：1989-01-01 00:00:00