Identification and removal of polymer- and aggregate-forming proteins in human plasma albumin preparations.

abstract：:In vivo immune phagocytosis of neonatal monocytes was significantly correlated to the extent of maternal HLA immunization. Monocytes from all 15 neonates of mothers with HLA antibodies show reduced immune phagocytosis. In contrast, this holds true for monocytes from only 6 out of 13 neonates of mothers without detecta...

journal_title：Vox sanguinis

authors： Neppert J,Mueller-Eckhardt G,Heine O

更新日期：1988-01-01 00:00:00

abstract：:Alloimmune neonatal thrombocytopenia (ANT) may cause intracranial haemorrhage in utero as well as at delivery. Recent management has concentrated on attempts to minimise fetal thrombocytopenia and prevent its complications. This report describes further experience with the use of repeated intravascular transfusions of...

journal_title：Vox sanguinis

authors： Murphy MF,Pullon HW,Metcalfe P,Chapman JF,Jenkins E,Waters AH,Nicolaides KH,Mibashan RS

更新日期：1990-01-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：:We here report 2 patients who have acquired two consecutive episodes each of acute hepatitis, within 6 months after blood transfusion. The clinical and biochemical course was typical of recurrent acute viral hepatitis, and the patients recovered completely after each episode. The first infection was probably caused by...

journal_title：Vox sanguinis

authors： Ben-Dov I,Fainaru M

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, transfusion transmission risk of Human T-cell lymphotropic virus -I/II (HTLV) is addressed by universal leucoreduction and universal antibody testing. We aimed to estimate the risk with the current policy, if testing only first-time donors and if testing were stopped. MATERIALS AND...

journal_title：Vox sanguinis

authors： O'Brien SF,Yi QL,Goldman M,Grégoire Y,Delage G

更新日期：2018-11-01 00:00:00

abstract：:We developed a new filter, 'Sepacell-PL', consisting of a blood administration set for the preparation of leukocyte-poor platelet concentrates at the patient's bedside. This filter is packed with 1.8 microns polyester fibers coated with a new polymer, and has a volume of 14 ml. Sepacell-PL removed more than 99% of the...

journal_title：Vox sanguinis

authors： Miyamoto M,Sasakawa S,Ishikawa Y,Ogawa A,Nishimura T,Kuroda T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Photochemical treatment (PCT) based on amotosalen and ultraviolet A light (UVA) demonstrated a wide range of pathogen inactivation. However, coagulation proteins are affected by this treatment. The aim of this study was to evaluate the coagulation parameters in apheresis plasma units after tha...

journal_title：Vox sanguinis

authors： de Valensart N,Rapaille A,Goossenaerts E,Sondag-Thull D,Deneys V

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated isometric muscle tension (applied tension) during blood donation reduces vasovagal symptoms in many donors. Experiencing vasovagal symptoms has been found to reduce blood donor return. However, does practicing applied tension improve blood donor return? Follow-up results from a random...

journal_title：Vox sanguinis

authors： Ditto B,Gilchrist PT,Holly CD,Dubuc S,Delage G,France CR

更新日期：2013-11-01 00:00:00

abstract：:OCTAPLAS is a cell-free standardized blood group specific human coagulation active plasma for transfusion. The viral safety is mainly based on the treatment with solvent/detergent. SD is known to irreversibly inactivate the lipid enveloped viruses including HIV 1 + 2, HBV and HCV and has been recommended both by Europ...

journal_title：Vox sanguinis

authors： Biesert L,Suhartono H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies of unknown specificity (AUS) are frequently identified in the pre-transfusion testing. These antibodies can be insignificant or potentially cause post-transfusion haemolysis. Information about the prevalence of clinically relevant AUS is still lacking. Our aim was to predict the pot...

journal_title：Vox sanguinis

authors： de Albuquerque da Veiga Conrado MC,Cardoso RA,Dezan MR,Oliveira VB,Neto ADC,Ziza KC,Krieger JE,Pereira AC,Sabino EC,Rocha V,Mendrone-Júnior A,Dinardo CL

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A multicentre trial was set up to evaluate the performance of a new leucodepletion protocol. MATERIALS AND METHODS:Filtration at high haematocrit was started during collection of red blood cell (RBC) products by apheresis with Trima. SAG-M was added after filtration through the filter. Haemat...

journal_title：Vox sanguinis

authors： Soli M,Blanco L,Riggert J,Martínez-Clavel A,Lucas C,Lunghi M,Belloni M,Wolf C,van Waeg G,Antoon M

更新日期：2001-01-01 00:00:00

abstract：:An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual ex...

journal_title：Vox sanguinis

authors： Dinning G,Doughty RW,Collins AK

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Red-blood-cells (RBCs) undergo structural and metabolic changes with prolonged storage, which ultimately may decrease their survival after transfusion. Although the storage-induced damage to RBCs has been rather well described biochemically, little is known about the mechanisms underlying the ...

journal_title：Vox sanguinis

authors： Hult A,Toss F,Malm C,Oldenborg PA

更新日期：2020-11-01 00:00:00

abstract：:Articles on the appropriateness of intention-to-treat (ITT) vs. as-treated (AT) analyses of randomized controlled trials (RCTs) have highlighted issues relevant to drug trials, such as approaches suitable for 'explanatory' vs. 'pragmatic' RCTs. These considerations are less relevant to transfusion medicine RCTs, espec...

journal_title：Vox sanguinis

authors： Vamvakas EC

更新日期：2008-10-01 00:00:00

abstract：:Platelet antibodies were looked for in 47 patients with autoimmune thrombocytopenia using a modification of the enzyme-linked assay previously described. Surface-bound antibodies measured as increased platelet-associated IgG were found in 32 (68%) of the patients. After incubation in test sera, the platelet-associated...

journal_title：Vox sanguinis

authors： Hegde UM,Bowes A,Powell DK,Joyner MV

更新日期：1981-11-01 00:00:00

abstract：:The clinical course and laboratory findings of a patient with autoimmune haemolytic anaemia due to anti-phospholipid antibodies and secondary to a systemic lupus erythematosus-like syndrome are described. IgG and IgM with anti-phospholipid activity coexisted in both sera and acid eluates prepared from the patient's re...

journal_title：Vox sanguinis

authors： Arvieux J,Schweizer B,Roussel B,Colomb MG

更新日期：1991-01-01 00:00:00

abstract：:To maximize the availability of platelet concentrates (PC) and minimize their outdate, competing criteria, a computer simulation model of platelet production and distribution was developed. Based on 2 years of actual platelet orders placed with a regional blood center, the simulation program generated daily platelet o...

journal_title：Vox sanguinis

authors： Katz AJ,Carter CW,Saxton P,Blutt J,Kakaiya RM

更新日期：1983-01-01 00:00:00

abstract：:The Gm allotype constitution of the autoantibody molecules and the serum Gm phenotypes were determined in 19 patients with autiommune hemolytic anemia of IgG type. The results showed that the known heterogeneity of the antierythrocyte autoantibodies in this disease concerns not only the immunoglobulin class and the is...

journal_title：Vox sanguinis

authors： Le Petit JC,Rivat L,François N,Ropartz C,Brizard CP

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Recent changes have resulted in the loss of 4% of the donor panel in the Republic of Ireland and 3% in Northern Ireland. In order to increase the number of donors in these two regions, it is important that transfusion service providers explore and understand the reasons, which prevent individuals from donati...

journal_title：Vox sanguinis

authors： Harrington M,Sweeney MR,Bailie K,Morris K,Kennedy A,Boilson A,O'Riordan J,Staines A

更新日期：2007-05-01 00:00:00

abstract：:The biochemical status of whole blood stored in containers fabricated of ethylene ethylacrylate (EEA) film was monitored at several times during 4 weeks of storage at 4 degrees C. Fifteen biochemical indicators were studied to reflect on erythrocyte integrity, cellular metabolism, plasma protein stability, and microag...

journal_title：Vox sanguinis

authors： Horowitz B,Rowe AW,Stryker MH,Van der Sande J,Waldman AA,Wong SC,Gass JD,Woods KR

更新日期：1985-01-01 00:00:00

abstract：:An autoantibody mimicking anti-S specificity is described in an S-s+ patient. The antibody was detected 2 weeks after transfusion. The direct antiglobulin test (DAT) was positive and the antibody was thought to be an alloantibody formed after the transfusion. Eighteen months later, the DAT was still positive and anti-...

journal_title：Vox sanguinis

authors： Puig N,Carbonell F,Soler MA,Perez MT,Arriaga F,Marty ML

更新日期：1987-01-01 00:00:00

abstract：:A new competitive solid phase radioimmunoassay (CLB-RIA) has been developed for the detection of HBAg and HBAb in human serum and plasma. In the assay, sheep antibodies to HBAg, covalently linked to an insoluble carrier, highly purified 125-I labelled HBAg and the serum or plasma sample are incubated for 20 h at room ...

journal_title：Vox sanguinis

authors： Duimel WJ,Brummelhuis HG

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study. METHODS:The progression to AIDS in relation to type of haemophilia,...

journal_title：Vox sanguinis

authors： Roosendaal G,van der Schouw Y,Mauser-Bunschoten E,Borleffs J,van den Berg H

更新日期：1998-01-01 00:00:00

abstract：:The international media attention to "bad blood" has fueled governmental action in countries around the world. Donor selection criteria continue to expand, focusing most recently on the possibility of exclusion due to intranasal cocaine use and, in the US, due to incarceration for more than 72 hours. As newer methods ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Fever is described in transfusion-associated circulatory overload (TACO), reflecting either comprehensive haemovigilance or an inflammatory pathobiology (such as congestion-associated atheroma disruptions). METHODS:Hospital haemovigilance data (1/1/2010-31/12/2012) were reviewed for TACO cases (frequency an...

journal_title：Vox sanguinis

authors： Parmar N,Pendergrast J,Lieberman L,Lin Y,Callum J,Cserti-Gazdewich C

更新日期：2017-01-01 00:00:00

abstract：:To determine what effect different preparative protocols and different platelet storage bags have on in vitro release, platelet concentrates were prepared according to two different protocols (group I: 2,200 g for 3.5 min followed by 4,900 g for 5 min; group II: 1,000 g for 9 min and 3,000 g for 20 min). The storage b...

journal_title：Vox sanguinis

authors： Snyder EL,Koerner TA Jr,Hezzey A

更新日期：1982-01-01 00:00:00

abstract：:Hepatitis E is considered an emerging disease that may be a threat in both developing and industrialized countries all over the world. The risk of chronic hepatitis E virus infection is higher among immunocompromised patients. This study aimed to assess the status of hepatitis E infection in patients with transfusion-...

journal_title：Vox sanguinis

authors： Klonizakis P,Gioula G,Exindari M,Apostolou C,Kotsiafti A,Vlachaki E

更新日期：2017-10-01 00:00:00

abstract：:Nowadays, risk of transfusion-transmitted infection has been substantially minimized by stringent donor eligibility screening and infectious disease testing. However, we report an interdiction of a blood donation containing varicella-zoster virus (VZV) by donor self-reporting of chickenpox. The donor developed varicel...

journal_title：Vox sanguinis

authors： Chan HM,Ho PL,Chan KH,Lin CK,Lee CK

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several pathogen inactivation methods currently applied to therapeutic plasma may result in products with different hemostatic properties. This study aims at evaluating and comparing the hemostatic potential of different therapeutic plasma preparations currently available in France. MATERIALS...

journal_title：Vox sanguinis

authors： Hacquard M,Lecompte T,Belcour B,Geschier C,Jacquot C,Jacquot E,Schneider T

更新日期：2012-05-01 00:00:00

abstract：:The present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. It is a suitable technique for measurement of these parameters in small samples wh...

journal_title：Vox sanguinis

authors： Kaplan JE,Blumenstock FA,Saba TM

更新日期：1979-01-01 00:00:00