Evaluation of the hemostatic potential including thrombin generation of three different therapeutic pathogen-reduced plasmas.

abstract：:The amount of H antigens on buccal epithelial cells (BEC) of secretors and non-secretors was measured by flow cytometry. H type 1 and H type 2 on BEC were detected with fluorescein-labelled Ulex europaeus lectin, and H type 2 was measured with mouse monoclonal antibody. Between 3.5 and 6 times more H antigen was detec...

journal_title：Vox sanguinis

authors： Rahat A,Stewart J,Blackwell CC,Weir DM

更新日期：1990-01-01 00:00:00

abstract：:Isoagglutinins were investigated following ABO-incompatible bone marrow transplantation. In major incompatibility anti-A tends to require more time to disappear than anti-B. Correspondingly, A erythrocytes require more time to become demonstrable. There is no such difference in major plus minor incompatibility. In min...

journal_title：Vox sanguinis

authors： Wernet D,Mayer G

更新日期：1992-01-01 00:00:00

abstract：:The pretreatment of LEW (RT-1l) rat recipients with antibody-coated BN (RT-1n) blood cells resulted in the suppression of the LEW antibody response against subsequent BN platelet and leukocyte transfusions. Both coating with homologous LEW-anti-BN serum or heterologous rabbit-anti-rat lymphocyte serum was effective. R...

journal_title：Vox sanguinis

authors： Süsal C,Terness P,Opelz G

更新日期：1990-01-01 00:00:00

abstract：:Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal anaemia with a risk for fetal death and to severe forms of neonatal hyperbilirubinaemia with a risk for kernicterus. Most severe cases are caused by anti-D,...

journal_title：Vox sanguinis

authors： de Haas M,Thurik FF,Koelewijn JM,van der Schoot CE

更新日期：2015-08-01 00:00:00

abstract：:A model of the Rh blood group system is proposed which is based on discontinuous gene structure. The R29 control subregion consists of a single exon flanked by introns. Following the R29 subregion, the R1 subregion exists as seven exon structures which alternate with introns. The expression of each exon is controlled ...

journal_title：Vox sanguinis

authors： Giorno R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Platelet function abnormalities have been reported in blood donors who have not consumed aspirin. Our objective was to identify factors other than aspirin that may contribute to impaired platelet function in qualified volunteer blood donors. MATERIALS AND METHODS:Blood samples were obtained f...

journal_title：Vox sanguinis

authors： Paglieroni TG,Janatpour K,Gosselin R,Crocker V,Dwyre DM,MacKenzie MR,Holland PV,Larkin EC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Repeated blood donation produces iron deficiency. Changes in dietary iron intake do not prevent donation-induced iron deficiency. Prolonging the interdonation interval or using oral iron supplements can mitigate donation-induced iron deficiency. The most effective operational methods for reduc...

journal_title：Vox sanguinis

authors： Bialkowski W,Bryant BJ,Schlumpf KS,Wright DJ,Birch R,Kiss JE,D'Andrea P,Cable RG,Spencer BR,Vij V,Mast AE

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:There are two presumed mechanisms for the pulmonary oedema in transfusion-related acute lung injury (TRALI). One is antibodies to leucocytes while the other is biologically active lipids. We evaluated the vascular injury due to the former. METHODS:The pulmonary vasculature was studied by light microscopy (L...

journal_title：Vox sanguinis

authors： Jensen HM,Galante JM,Kysar PE,Tolstikov VV,Reddy KJ,Holland PV

更新日期：2010-02-01 00:00:00

abstract：:A substantial body of animal data indicates that transmissible spongiform encephalopathies (TSEs) are transmitted through blood. These data have been augmented in the past year by reports that two recipients of red cells from donors with variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom have acquired this...

journal_title：Vox sanguinis

authors： Farrugia A,Ironside JW,Giangrande P

更新日期：2005-11-01 00:00:00

abstract：:Although hemovigilance is not a word used commonly in the United States, the concept of monitoring morbidity associated with blood transfusion is accepted widely. Currently, quality management focuses on error avoidance rather than error detection in both the "manufacturing" and "clinical" aspects of blood banking. "M...

journal_title：Vox sanguinis

authors： Menitove JE

更新日期：1998-01-01 00:00:00

abstract：:A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are ...

journal_title：Vox sanguinis

authors： Mayer S,Hauptmann G,Tongio MM

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Since the first cases of acquired immunodeficiency syndrome in persons with haemophilia were reported in 1982, much has been written about the consequences of human immunodeficiency virus (HIV) contamination of the blood supply. Relatively little attention has been paid to similar hepatitis C virus (HCV) con...

journal_title：Vox sanguinis

authors： Angelotta C,McKoy JM,Fisher MJ,Buffie CG,Barfi K,Ramsey G,Frohlich L,Bennett CL

更新日期：2007-08-01 00:00:00

abstract：:To elucidate the possible influence of previous blood transfusion on immune functions, the transfusion history of 153 patients admitted to hospital for elective colorectal surgery was correlated with lymphocyte subsets and natural killer (NK) cell function. The subsets determined were CD2, CD3, CD4, CD8, CD16, CD20, C...

journal_title：Vox sanguinis

authors： Mathiesen O,Lund L,Brodthagen U,Gandrup P,Grunnet N,Balslev I,Jersild C

更新日期：1994-01-01 00:00:00

abstract：:Prothrombin complex concentrates prepared for clinical use are reviewed with emphasis on frequently observed adverse reactions such as viral hepatitis and thromboembolic complications. Preparation procedures and quality control are described briefly, and the use of these concentrates in the treatment of hemophilia A p...

journal_title：Vox sanguinis

authors： Chandra S,Brummelhuis HG

更新日期：1981-11-01 00:00:00

abstract：:A non-blow-molded LE-2 polyolefin (PO) container was developed to store single-donor apheresis platelet concentrates (PCs) processed by the Haemonetics Plasma Collecting System (PCS) at 22 degrees C for over 1 day. We molded PO containers with heat-sealing of light-weight polymer alloy films with a thickness of 0.25 m...

journal_title：Vox sanguinis

authors： Shimizu T,Kouketsu K,Kamiya T,Futagawa H,Hirose S

更新日期：1989-01-01 00:00:00

abstract：:The international media attention to "bad blood" has fueled governmental action in countries around the world. Donor selection criteria continue to expand, focusing most recently on the possibility of exclusion due to intranasal cocaine use and, in the US, due to incarceration for more than 72 hours. As newer methods ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion is associated with a risk of infection and alloimmunization. Pathogen reduction using riboflavin and UV light (Mirasol treatment) inactivates pathogens and leucocytes. With increasing adoption of the technology in clinical use, regulatory agencies have recommended the introduction ...

journal_title：Vox sanguinis

authors： Bakkour S,Chafets DM,Wen L,van der Meer PF,Mundt JM,Marschner S,Goodrich RP,Busch MP,Lee TH

更新日期：2014-11-01 00:00:00

abstract：:Manual plasmapheresis is done worldwide on both paid donors, and to a much smaller extent on volunteer donors in order to generate source plasma to be fractionated into albumin, clotting factor concentrates, and gamma globulin. Automated technology has now been developed utilizing both centrifugal, and membrane separa...

journal_title：Vox sanguinis

authors： Gilcher RO

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The A2 is a very rare phenotype in the ABO blood group system in the Oriental population. It corresponds to a special ABO allele encoding a glycosyltransferase that is capable of synthesizing A2 antigens, which is weaker than the typical A antigen. In this study, we report a novel A2 allele in...

journal_title：Vox sanguinis

authors： Chen DP,Tseng CP,Wang WT,Sun CF

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Factor VIII (FVIII) levels are used as a quality marker of fresh-frozen plasma (FFP); however, other clotting factors are not routinely measured. METHODS:We assessed additional haemostatic parameters and the dynamics of coagulation using Thrombelastography (TEG) and a thrombin generation test (TGT). FFP was...

journal_title：Vox sanguinis

authors： Lawrie AS,Cardigan RA,Williamson LM,Machin SJ,Mackie IJ

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：:A population of human erythrocytes (free A3 cells) which was entirely unagglutinable with anti-A hemagglutinins was successfully separated from human blood group A3 erythrocytes by affinity chromatography on a column of lima bean anti-A hemagglutinin (LBH)-Sepharose. The hemagglutinating and the binding properties of ...

journal_title：Vox sanguinis

authors： Oguchi Y,Kawaguchi T,Suzuta T,Osawa T

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Analysis of haemoglobin (Hb) dilution after bleeding is a simple, inexpensive and non-invasive method to estimate blood loss. Blood volume is estimated, taking sex, weight and height into account. The Hb concentration before and after blood loss is analysed and, from the difference, the blood ...

journal_title：Vox sanguinis

authors： Meunier A,Petersson A,Good L,Berlin G

更新日期：2008-08-01 00:00:00

abstract：:The US blood safety vigilance system is composed of a network of interwoven programs, now organized under a formal structure, with the Assistant Secretary of Health and DHHS Blood Safety Committee bearing overall responsibility. It takes advantage of the breadth of expertise and close collaborative relationship of tra...

journal_title：Vox sanguinis

authors： Busch M,Chamberland M,Epstein J,Kleinman S,Khabbaz R,Nemo G

更新日期：1999-01-01 00:00:00

abstract：:We developed a new filter, 'Sepacell-PL', consisting of a blood administration set for the preparation of leukocyte-poor platelet concentrates at the patient's bedside. This filter is packed with 1.8 microns polyester fibers coated with a new polymer, and has a volume of 14 ml. Sepacell-PL removed more than 99% of the...

journal_title：Vox sanguinis

authors： Miyamoto M,Sasakawa S,Ishikawa Y,Ogawa A,Nishimura T,Kuroda T

更新日期：1989-01-01 00:00:00

abstract：:Three 'A1 weak B' blood groups found in two generations of a Romanian family were studied with quantitative and thermodynamic assays in order to determine if they derive from 'A1Bx' or from 'cis AB' genotypes, what cannot be achieved by the genetics. ...

journal_title：Vox sanguinis

authors： Lopez M,Danielescu M,Liberge G,Salmon C

更新日期：1975-01-01 00:00:00

abstract：:The factors that impact upon successful bone marrow transplantation leading to immunologic reconstitution in severe combined immune deficiency (SCID). Wiskott-Aldrich syndrome, and in other lethal congenital immunodeficiencies are reviewed. Evidence is presented that graft-versus-host disease (GVHD) can be abrogated b...

journal_title：Vox sanguinis

authors： O'Reilly RJ,Brochstein J,Collins N,Keever C,Kapoor N,Kirkpatrick D,Kernan N,Dupont B,Burns J,Reisner Y

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The absence of the red cell antigens P, P1 and Pk , known as 'p', represents an extremely rare red cell phenotype. Individuals with this phenotype spontaneously form anti-PP1Pk isoantibodies, associated with severe haemolytic transfusion reactions, recurrent spontaneous abortion and haemolytic disease of the...

journal_title：Vox sanguinis

authors： Di Ciaccio P,Cutts B,Alahakoon TI,Dennington PM,Soo LA,Curnow J

更新日期：2020-12-16 00:00:00

abstract：:We investigated the effects of gravitational force and three different plastic formulations of the storage bags on the quality of stored platelets by measuring the changes in platelet-associated immunoglobulin G (IgG) and two antigenic markers of the third component of human complement (C3), C3d and C3c. Pooled platel...

journal_title：Vox sanguinis

authors： Szymanski IO,Odgren PR,Teno RA,Jacobson MS,Surgenor DM

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The risk of transfusion-transmitted human T-lymphotropic virus type 1 infection (TT-HTLV-1) after prestorage leucocyte reduction (LR) remains unknown, as the proviral load in the blood component that would cause TT-HTLV-1 is undetermined. On the basis of the distribution of HTLV-1 proviral loa...

journal_title：Vox sanguinis

authors： Sobata R,Matsumoto C,Uchida S,Suzuki Y,Satake M,Tadokoro K

更新日期：2015-08-01 00:00:00