Prothrombin complex concentrates for clinical use.

abstract：:OCTAPLAS is a cell-free standardized blood group specific human coagulation active plasma for transfusion. The viral safety is mainly based on the treatment with solvent/detergent. SD is known to irreversibly inactivate the lipid enveloped viruses including HIV 1 + 2, HBV and HCV and has been recommended both by Europ...

journal_title：Vox sanguinis

authors： Biesert L,Suhartono H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies to antigens in the Kell blood group system, especially anti-KEL1, are involved in both haemolytic disease of the newborn and foetus and haemolytic transfusion reactions. Correct typing results are important and discrepancies between serologic and genetic typing must be resolved. Her...

journal_title：Vox sanguinis

authors： Wester ES,Steffensen R,Ligthart PC,Vad J,de Haas M,Storry JR,Olsson ML

更新日期：2010-08-01 00:00:00

abstract：:Idiopathic analbuminemia was fortuitously detected in a 30-year-old Italian woman. No associated disease condition could be revealed in this patient, the only consistent finding being a slight tendency to develop ankle edema. Asthenia and a moderate hypotension were also recorded. Trace amounts (5.2 mg/100 ml) of seru...

journal_title：Vox sanguinis

authors： Dammacco F,Miglietta A,D'Addabbo A,Fratello A,Moschetta R,Bonomo L

更新日期：1980-09-01 00:00:00

abstract：OBJECTIVES:Reconstitution of hematopoiesis by means of peripheral blood stem cells is a valid alternative to autologous bone marrow transplantation. The aim of this investigation was to increase the efficiency of collection of circulating blood progenitor cells and to obtain a purer product for transplant. METHODS:We ...

journal_title：Vox sanguinis

authors： Menichella G,Lai M,Pierelli L,Vittori M,Serafini R,Ciarli M,Foddai ML,Salerno G,Sica S,Scambia G,Leone G,Bizzi B

更新日期：1997-01-01 00:00:00

abstract：:A method to coat unsensitized erythrocytes with fragments of C3 and C4 using autologous serum, in order to study complement receptor-dependent function of the fixed macrophage system, is presented. After incubation with serum under optimal conditions, at least 90% of the cells had C3b/iC3b deposited on the surface, wi...

journal_title：Vox sanguinis

authors： Nilsson Ekdahl K,Lööf L,Nilsson UR,Nilsson B

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In Canada, Héma-Québec is considering the possibility of allowing men who have sex with men (MSM) to donate plasma for fractionation combined with a mandatory quarantine period. This study aims to assess the acceptability and operational feasibility of the programme in the targeted population....

journal_title：Vox sanguinis

authors： Caruso J,Germain M,Godin G,Myhal G,Pronovost F,Morin M,Otis J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Analysis of reports of incidents, involving ABO incompatibility suggests that the main problem is poor interpretation of the pretransfusion bedside compatibility test (PBCT). We studied sources of error as experienced by nurses as to the blood groups of donor blood and of the recipient. MATERI...

journal_title：Vox sanguinis

authors： Dujardin PP,Salmi LR,Ingrand P

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A major requirement of a hepatitis C virus (HCV) RNA nucleic acid amplification technology (NAT) assay validation is the ability of the assay to detect the six major genotypes of HCV with equivalent sensitivities. The aim of this study was to characterize and calibrate an HCV genotype panel fo...

journal_title：Vox sanguinis

authors： Saldanha J,Heath A,Collaborative Study Group.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Routine serologic D typing does not distinguish between weak D subtypes and partial D phenotypes. The goal of this study was to validate the performance of the ID RHD XT genotyping assay. MATERIAL AND METHODS:Previously serotyped samples for D antigen (n = 1000; 16% weak D serotyped donors) w...

journal_title：Vox sanguinis

authors： Molano A,Apraiz I,España P,Azkarate M,Vesga MÁ,Rubia M,Piedrabuena M,Puente F,Veldhuisen B,van der Schoot E,Tejedor D,López M

更新日期：2018-10-01 00:00:00

abstract：:The domain specificity of anti-factor VIII (FVIII) inhibitor antibodies was determined in assays using FVIII domains generated by thrombin cleavage or expressed as recombinant polypeptides to neutralise the inhibitor. The results revealed the existence of three major types of inhibitors, and various combinations of th...

journal_title：Vox sanguinis

authors： Scandella D

更新日期：1999-01-01 00:00:00

abstract：:An alternative to blood transfusion, based on oxygen-carrying solutions, has been sought for over a century. The present 'first-generation' haemoglobin-products were based on observations that crosslinking with, for example, glutaraldehyde, overcame subunit dissociation and renal toxicity. Experience with these soluti...

journal_title：Vox sanguinis

authors： Winslow RM

更新日期：2006-08-01 00:00:00

abstract：:A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are ...

journal_title：Vox sanguinis

authors： Mayer S,Hauptmann G,Tongio MM

更新日期：1976-01-01 00:00:00

abstract：:If leukocyte- and platelet-poor red cells have been processed and stored in closed bags, their delivery, especially on holidays, will be easy. The modified warm-centrifuge method was applied to a quadruple bag prepared for such purpose. Red cells were processed in the first bag by the centrifugation of whole blood. Th...

journal_title：Vox sanguinis

authors： Shimizu T,Ishikawa Y,Tsurumi H,Hibi S,Takakura R,Morishima Y,Hasegawa I,Goto S

更新日期：1986-01-01 00:00:00

abstract：:Bacterial contamination of platelet concentrates poses a major post-transfusion infectious risk. This study was aimed at evaluating the efficacy of the BacTx(®) assay (Immunetics Inc.) for bacterial detection in leucocyte-reduced buffy coat platelet pools and for its sensitivity in detecting clinical isolates, includi...

journal_title：Vox sanguinis

authors： Ramirez-Arcos S,Kou Y,Perkins H

更新日期：2014-08-01 00:00:00

abstract：:Acute posttransfusion hepatitis C was reported in a recipient of 3 units of red cells. The recipient became acutely icteric 6 weeks after transfusion, and HCV infection was diagnosed. Stored serum samples of the 3 implicated donations, which were negative with ELISA-2, were retested by PCR and 3rd-generation antibody ...

journal_title：Vox sanguinis

authors： Vrielink H,van der Poel CL,Reesink HW,Zaaijer HL,Lelie PN

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age. MATERIALS AND METHODS:Preterm infants receiving blood transfusion were recruited to three groups: 1-7 (group 1; n = 20), 8-...

journal_title：Vox sanguinis

authors： Banerjee J,Leung TS,Aladangady N

更新日期：2016-11-01 00:00:00

abstract：:The international media attention to "bad blood" has fueled governmental action in countries around the world. Donor selection criteria continue to expand, focusing most recently on the possibility of exclusion due to intranasal cocaine use and, in the US, due to incarceration for more than 72 hours. As newer methods ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A 2-year-old female with neuroblastoma needed In(b-), E- red blood cells (RBCs). No units were available at the blood centre (BC) nor in the rare donor programme member's inventories. BC's Immunohematology Reference Laboratory (IRL) and its marketing department concentrated on recruiting and t...

journal_title：Vox sanguinis

authors： Gammon RR,Tyler L,Alvarez H,Benitez N,Nance S,Burton A,Delk A,Bright F,Sawh D,Forbes S

更新日期：2020-12-21 00:00:00

abstract：BACKGROUND:The absence of the red cell antigens P, P1 and Pk , known as 'p', represents an extremely rare red cell phenotype. Individuals with this phenotype spontaneously form anti-PP1Pk isoantibodies, associated with severe haemolytic transfusion reactions, recurrent spontaneous abortion and haemolytic disease of the...

journal_title：Vox sanguinis

authors： Di Ciaccio P,Cutts B,Alahakoon TI,Dennington PM,Soo LA,Curnow J

更新日期：2020-12-16 00:00:00

abstract：:Native hemoglobin in the form of stroma-free hemoglobin cannot be used as blood substitute. Hemoglobin has to be modified either molecularly or encapsulated. First generation molecularly modified ultrapure hemoglobins are now in clinical trial--some in Phase III. There are a number of these. Polyhemoglobin is formed b...

journal_title：Vox sanguinis

authors： Chang TM

更新日期：1998-01-01 00:00:00

abstract：:Some effector functions of various immunoglobulin (IgG) preparations have been compared. Tests for opsonic activity were performed in vitro with human peripheral blood leukocytes and in vivo with mice. The augmentation effects on luminol-dependent chemiluminescence were investigated with human leukocytes. The compleme...

journal_title：Vox sanguinis

authors： Yasuda H,Yajima T,Tanii T,Ashiba T,Iwata M

更新日期：1986-01-01 00:00:00

abstract：:The results of testing RoHarr cells with panels of monoclonal anti-D suggest that the D antigen (referred to as DHar) encoded by the haplotype (D)c(e) Rh33 is a partial D antigen. IgM monoclonal anti-D are more efficient than IgG monoclonal anti-D in detecting DHar.DHar expresses some but not all of both epD5 and epD6...

journal_title：Vox sanguinis

authors： Wallace M,Lomas-Francis C,Tippett P

更新日期：1996-01-01 00:00:00

abstract：:The results of the serological typing and the patterns of restriction fragment length polymorphisms for the detection of HLA-DR gene products are compared. The data shown demonstrate that the use of DNA typing gives a clearer definition of the HLA-DR antigens and that the HLA-DR polymorphism is greater than detected b...

journal_title：Vox sanguinis

authors： Nagy M,Mayr WR,Menzel GR

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Warm autoantibodies (WAA) are antibodies that react with an antigen on a patient's own red-blood-cells and can complicate compatibility testing whether or not they cause clinical haemolysis. The goal of this study was to understand the overall prevalence of WAA, the risk of RBC alloimmunization and determine...

journal_title：Vox sanguinis

authors： Delaney M,Apelseth TO,Bonet Bub C,Cohn CS,Dunbar NM,Mauro Kutner J,Murphy M,Perelman I,Selleng K,Staves J,Wendel S,Ziman A,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Fetal RHD genotyping of cell-free maternal plasma DNA from RhD negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment worksho...

journal_title：Vox sanguinis

authors： Clausen FB,Hellberg Å

更新日期：2020-07-01 00:00:00

abstract：:Since its discovery, human plasminogen (PLG) polymorphism has received widespread acceptance in population genetics and forensic haematology. Due to the large number of variant alleles described, a PLG reference typing and Plasminogen Symposium was held, at which a nomenclature proposal was inaugurated. The technology...

journal_title：Vox sanguinis

authors： Skoda U,Bertrams J,Dykes D,Eiberg H,Hobart M,Hummel K,Kühnl P,Mauff G,Nakamura S,Nishimukai H

更新日期：1986-01-01 00:00:00

abstract：:Early and regular blood transfusion therapy in patients with homozygous beta-thalassaemia decreases the complications of severe anaemia and prolongs survival. In the long term, however, the beneficial effects of transfusions are limited by the organ damage resulting from iron overload, a consequence of the body's limi...

journal_title：Vox sanguinis

authors： Prati D

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania, which are intracellular parasites of monocytes and macrophages. Transmission of the organism has been observed by transfusion of infected blood from asymptomatic donors to immunocompromised recipients, leading to...

journal_title：Vox sanguinis

authors： Wagner SJ,Skripchenko A,Salata J,Cardo LJ

更新日期：2006-08-01 00:00:00

abstract：:An IgM kappa cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)-treated RBC. It resembled anti-Me cold agglutinin in these serological findings. However, the activity of this agglutinin against RBC was markedly de...

journal_title：Vox sanguinis

authors： Kajii E,Ikemoto S

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous data that showed maintenance of reticulocyte percentage in whole blood stored in CPDA-1 have led to the assumption that reticulocyte maturation becomes arrested during refrigerated storage. However, reticulocyte behaviour in red-blood-cell units stored in additive solutions has not ye...

journal_title：Vox sanguinis

authors： Urbina A,Palomino F

更新日期：2013-05-01 00:00:00