Red-blood-cell alloimmunization and prophylactic antigen matching for transfusion in patients with warm autoantibodies.

abstract：:The biochemical status of whole blood stored in containers fabricated of ethylene ethylacrylate (EEA) film was monitored at several times during 4 weeks of storage at 4 degrees C. Fifteen biochemical indicators were studied to reflect on erythrocyte integrity, cellular metabolism, plasma protein stability, and microag...

journal_title：Vox sanguinis

authors： Horowitz B,Rowe AW,Stryker MH,Van der Sande J,Waldman AA,Wong SC,Gass JD,Woods KR

更新日期：1985-01-01 00:00:00

abstract：:There is almost general agreement that removal of leukocytes from blood components reduces the incidence of HLA-antibody formation and refractoriness to random platelet transfusions. Recently filters have become available, which are able to reduce leukocyte contamination in platelet suspensions with acceptable platele...

journal_title：Vox sanguinis

authors： Novotny VM,van Doorn R,Rozier Y,D'Amaro J,Harvey MS,Brand A

更新日期：1992-01-01 00:00:00

abstract：:Employing standardized IgG-coated 51Cr-labelled human red blood cells (RBC), variation in rosette formation among monolayers obtained from 10 healthy donors was defined, as well as variation among 24 sequential monolayers obtained from one healthy donor and 8 sequential monolayers from a second healthy donor over a 4-...

journal_title：Vox sanguinis

authors： Munn LR,Chaplin H Jr

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A 2-year-old female with neuroblastoma needed In(b-), E- red blood cells (RBCs). No units were available at the blood centre (BC) nor in the rare donor programme member's inventories. BC's Immunohematology Reference Laboratory (IRL) and its marketing department concentrated on recruiting and t...

journal_title：Vox sanguinis

authors： Gammon RR,Tyler L,Alvarez H,Benitez N,Nance S,Burton A,Delk A,Bright F,Sawh D,Forbes S

更新日期：2020-12-21 00:00:00

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. MATERIALS AND METHODS:The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelet...

journal_title：Vox sanguinis

authors： Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：:BOW is a 'new' low-frequency red-cell antigen, detected in 2 unrelated English blood donors, that is sensitive to alpha-chymotrypsin and pronase. Anti-BOW is present in many polyspecific reagents used to define low-frequency antigens. Red-cell groups of the proposita, R.B., and her family show that the BOW blood group...

journal_title：Vox sanguinis

authors： Chaves MA,Leak MR,Poole J,Giles CM

更新日期：1988-01-01 00:00:00

abstract：:The clinical course and laboratory findings of a patient with autoimmune haemolytic anaemia due to anti-phospholipid antibodies and secondary to a systemic lupus erythematosus-like syndrome are described. IgG and IgM with anti-phospholipid activity coexisted in both sera and acid eluates prepared from the patient's re...

journal_title：Vox sanguinis

authors： Arvieux J,Schweizer B,Roussel B,Colomb MG

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Recombinant activated factor VII (rFVIIa, NovoSeven) has been used off-label for various conditions. A protocol for its use in acute, uncontrolled life-threatening bleeding, was devised and employed. A haematologist/transfusion specialist was assigned as a member of the team. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Mayo A,Misgav M,Kluger Y,Geenberg R,Pauzner D,Klausner J,Ben-Tal O

更新日期：2004-07-01 00:00:00

abstract：:The use of granulocyte transfusions in profoundly neutropenic patients has increased markedly in recent years. Whenever a pulmonary infiltrate develops during the course of these transfusions, the question arises as to what role the transfusions are playing and whether the transfusions should be discontinued to preven...

journal_title：Vox sanguinis

authors： Karp DD,Ervin TJ,Tuttle S,Gorgone BC,Lavin P,Yunis EJ

更新日期：1982-02-01 00:00:00

abstract：:We have studied the IgE content of different lots of commercial intravenous IgG preparations used in our day hospital as replacement therapy for patients with agammaglobulinemia. Two enzymatic methods were used: Phadezym and FAST. The average amounts of IgE detected in Endobulin and Sandoglobulin lots were very high w...

journal_title：Vox sanguinis

authors： Paganelli R,Quinti I,D'Offizi GP,Papetti C,Cabello A,Aiuti F

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A major requirement of a hepatitis C virus (HCV) RNA nucleic acid amplification technology (NAT) assay validation is the ability of the assay to detect the six major genotypes of HCV with equivalent sensitivities. The aim of this study was to characterize and calibrate an HCV genotype panel fo...

journal_title：Vox sanguinis

authors： Saldanha J,Heath A,Collaborative Study Group.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Platelet function abnormalities have been reported in blood donors who have not consumed aspirin. Our objective was to identify factors other than aspirin that may contribute to impaired platelet function in qualified volunteer blood donors. MATERIALS AND METHODS:Blood samples were obtained f...

journal_title：Vox sanguinis

authors： Paglieroni TG,Janatpour K,Gosselin R,Crocker V,Dwyre DM,MacKenzie MR,Holland PV,Larkin EC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Host- or donor-derived alloimmune thrombocytopenia can develop after non-myeloablative allogeneic haematopoietic stem cell transplantation (HSCT). We report the first case of host-derived HPA-1a antibodies. CASE REPORT:A 52-year-old male patient received HSCT from his human leucocyte antigen ...

journal_title：Vox sanguinis

authors： Macher S,Schallmoser K,Staber PB,Neumeister P,Posch U,Lanzer G,Panzer S

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Plasma exchange (PE) and immunoadsorption with the Immusorba TR-350 column (IA) are used to remove autoantibodies from plasma in acute neurological autoimmune disorders. The impact of IA on coagulation and on low molecular weight heparin (LMWH) levels in comparison with PE was investigated. P...

journal_title：Vox sanguinis

authors： Koessler J,Kobsar A,Kuhn S,Koessler A,Yilmaz P,Weinig E,Putz E,Boeck M,Klinker E

更新日期：2015-01-01 00:00:00

abstract：:The present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. It is a suitable technique for measurement of these parameters in small samples wh...

journal_title：Vox sanguinis

authors： Kaplan JE,Blumenstock FA,Saba TM

更新日期：1979-01-01 00:00:00

abstract：:The domain specificity of anti-factor VIII (FVIII) inhibitor antibodies was determined in assays using FVIII domains generated by thrombin cleavage or expressed as recombinant polypeptides to neutralise the inhibitor. The results revealed the existence of three major types of inhibitors, and various combinations of th...

journal_title：Vox sanguinis

authors： Scandella D

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The clinical significance of immune thrombocytopenia (ITP) is mainly reflected by bleeding and/or bleeding risks, which, in some cases, cannot be adequately controlled by standard therapy. Tranexamic acid (TA) is increasingly used in preventing and reducing bleeding in several medical settings...

journal_title：Vox sanguinis

authors： Mayer B,Salama A

更新日期：2017-11-01 00:00:00

abstract：:We developed a photodynamic method to inactivate viruses in human fresh plasma. Single plasma bags were illuminated with visible light in the presence of low doses of phenothiazine dyes like methylene blue or toluidine blue. By this treatment the infectivity of different enveloped viruses including the causative agent...

journal_title：Vox sanguinis

authors： Lambrecht B,Mohr H,Knüver-Hopf J,Schmitt H

更新日期：1991-01-01 00:00:00

abstract：:The commercial immune serum globulin (ISG) product is suitable for use in passive immunization only by intramuscular administration; intravenous use results in vasomotor side reactions. We report the functional characterization of a chemically modified ISG (MISG) that is essentially free of nonspecific complement-bind...

journal_title：Vox sanguinis

authors： Schroeder DD,Tankersley DL,Lundblad JL

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to assess potentially relevant clinical characteristics which influence the decision to transfuse red cells in critically ill patients with low haemoglobin concentrations (6.0-10.0 g/dl). MATERIALS AND METHODS:This was a retrospective observational cohort study of pa...

journal_title：Vox sanguinis

authors： Kranenburg FJ,le Cessie S,Caram-Deelder C,van der Bom JG,Arbous MS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although transfusion-transmitted infections are rare, non-infectious complications occur relatively frequently. Solvent/detergent-treated fresh-frozen plasma (SD-FFP) has been shown to reduce the frequency of both types of complication, although previous economic evaluations failed to consider...

journal_title：Vox sanguinis

authors： Riedler GF,Haycox AR,Duggan AK,Dakin HA

更新日期：2003-08-01 00:00:00

abstract：:False-positive enzyme immunoassay (EIA) tests in blood donors receiving influenza vaccine were first reported in 1991. We conducted follow-up testing for 6 months of those donors with multiply reactive, but unconfirmed EIA (at least 2 positives in anti-HCV-1.0, anti-HIV-1, and anti-HTLV-I assays) with a history of rec...

journal_title：Vox sanguinis

authors： Arnold NL,Slade BA,Jones MM,Popovsky MA

更新日期：1994-01-01 00:00:00

abstract：:Detailed serological investigation of five examples of anti-Jka revealed considerable heterogeneity in their characteristics. All the sera were investigated by the antiglobulin technique, with and without complement and by a range of sensitization and testing methods. Three were readily detected in the presence of com...

journal_title：Vox sanguinis

authors： Howell P,Giles CM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In this EQA study a novel approach was used to assess the performance of blood centres and blood product manufacturers in detecting the possible contamination of plasma with HCV, HIV and HBV by NAT. MATERIALS AND METHODS:A panel of 12 samples, three negative and three positive for each virus,...

journal_title：Vox sanguinis

authors： Pisani G,Marino F,Cristiano K,Bisso GM,Mele C,Luciani F,Wirz M,Gentili G,External Quality Assessment Participants.

更新日期：2008-07-01 00:00:00

abstract：:A number of parasitic diseases are known, or suspected to be transmitted by blood transfusion. Of greatest concern are malaria and Chagas' disease, but babesia, leishmania and toxoplasmosis also offer risk in particular locations or circumstances. Some of these parasites may be imported into non-endemic areas as a res...

journal_title：Vox sanguinis

authors： Dodd RY

更新日期：1998-01-01 00:00:00

abstract：:A new therapeutic plasma exchange device developed by Sarns Inc./3M was evaluated in plasmapheresis of 20 healthy volunteers and in a multicenter clinical study of therapeutic plasma exchange that included 49 patients. Safety and efficacy of plasma separation from whole blood were assessed for a module that contains D...

journal_title：Vox sanguinis

authors： Kurtz SR,Carey PM,McGill M,Pineda AA,Zaroulis CG,Case MT

更新日期：1987-01-01 00:00:00

abstract：:For emergent warfarin reversal, four-factor prothrombin complex concentrates (4FPCCs) are recommended by many international guidelines. We surveyed international clinical sites including members of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Most sites have emergent warfarin reversal protocol...

journal_title：Vox sanguinis

authors： Gorlin J,Kinney S,Fung MK,Tinmouth A,BEST Collaborative.

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:During platelet storage an array of deleterious changes occur, through mechanisms not fully understood, which impair platelet haemostasis. Transfused platelets should maintain the integrated networks of signalling pathways that regulate platelet activation and functionality. We hypothesized th...

journal_title：Vox sanguinis

authors： Hernández-Hernández A,Sánchez-Bernal C,Rodríguez MC,Gómez FP,Llanillo M,Sánchez-Yagüe J

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Currently, plasma fractionation involves multiple processing steps using established methods such as ethanol precipitation and column chromatography. The known limitations associated with conventional purification techniques, combined with strict regulations on safety and high demand for parti...

journal_title：Vox sanguinis

authors： Li G,Stewart R,Conlan B,Gilbert A,Roeth P,Nair H

更新日期：2002-11-01 00:00:00