Abstract:
:Detailed serological investigation of five examples of anti-Jka revealed considerable heterogeneity in their characteristics. All the sera were investigated by the antiglobulin technique, with and without complement and by a range of sensitization and testing methods. Three were readily detected in the presence of complement, while two were detectable with anti-IgG, providing a spin test was used. Complement was bound by all and resulted in enhanced reactions, particularly when slide/tile tests were used. The study emphasizes that anti-complement (C3) is an essential component of polyspecific antiglobulin reagents used in cross-matching, enabling the ready detection of these clinically important antibodies.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Howell P,Giles CMdoi
10.1111/j.1423-0410.1983.tb01897.xsubject
Has Abstractpub_date
1983-01-01 00:00:00pages
129-38issue
2eissn
0042-9007issn
1423-0410journal_volume
45pub_type
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