A detailed serological study of five anti-Jka sera reacting by the antiglobulin technique.

Abstract:

:Detailed serological investigation of five examples of anti-Jka revealed considerable heterogeneity in their characteristics. All the sera were investigated by the antiglobulin technique, with and without complement and by a range of sensitization and testing methods. Three were readily detected in the presence of complement, while two were detectable with anti-IgG, providing a spin test was used. Complement was bound by all and resulted in enhanced reactions, particularly when slide/tile tests were used. The study emphasizes that anti-complement (C3) is an essential component of polyspecific antiglobulin reagents used in cross-matching, enabling the ready detection of these clinically important antibodies.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Howell P,Giles CM

doi

10.1111/j.1423-0410.1983.tb01897.x

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

129-38

issue

2

eissn

0042-9007

issn

1423-0410

journal_volume

45

pub_type

杂志文章
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