Multiple epitopes recognised by human monoclonal IgM anti-D antibodies.

abstract：BACKGROUND AND OBJECTIVES:Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. MATERIAL AND METHODS:To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets conce...

journal_title：Vox sanguinis

authors： Brito F,Cordey S,Delwart E,Deng X,Tirefort D,Lemoine-Chaduc C,Zdobnov E,Lecompte T,Kaiser L,Waldvogel-Abramowski S,Preynat-Seauve O

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:There are two presumed mechanisms for the pulmonary oedema in transfusion-related acute lung injury (TRALI). One is antibodies to leucocytes while the other is biologically active lipids. We evaluated the vascular injury due to the former. METHODS:The pulmonary vasculature was studied by light microscopy (L...

journal_title：Vox sanguinis

authors： Jensen HM,Galante JM,Kysar PE,Tolstikov VV,Reddy KJ,Holland PV

更新日期：2010-02-01 00:00:00

abstract：:The nature of the receptor sites for several agglutinins is characterized by hemagglutination inhibition assays. The inhibitory activity of human erythrocytes glycoproteins, from which sialic acid, sialic acid and galactose or alkali-labile oligosaccharides have been removed, is compared to the inhibitory effect of co...

journal_title：Vox sanguinis

authors： Dahr W,Uhlenbruck G,Bird GW

更新日期：1975-01-01 00:00:00

abstract：:The amount of H antigens on buccal epithelial cells (BEC) of secretors and non-secretors was measured by flow cytometry. H type 1 and H type 2 on BEC were detected with fluorescein-labelled Ulex europaeus lectin, and H type 2 was measured with mouse monoclonal antibody. Between 3.5 and 6 times more H antigen was detec...

journal_title：Vox sanguinis

authors： Rahat A,Stewart J,Blackwell CC,Weir DM

更新日期：1990-01-01 00:00:00

abstract：:A family is presented, in which the mother developed strong neutrophil granulocyte-specific antibodies with the specificity anti-NA. The first and third children, both NA1-positive, suffered from severe transient neonatal neutropenia, but the second child, NA1-negative, did not. Anti-NA1 antibodies were detectable in ...

journal_title：Vox sanguinis

authors： Verheugt FW,van Noord-Bokhorst JC,von dem Borne AE,Engelfriet CP

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Polymorphonuclear neutrophils (PMNs) play important roles in the host immune defence. This study was performed to identify roles of PMNs other than those already known. MATERIALS AND METHODS:PMNs were separated from the peripheral blood of healthy individuals and stored in vitro for 24 h in t...

journal_title：Vox sanguinis

authors： Nishimura M,Mitsunaga S,Juji T

更新日期：2002-04-01 00:00:00

abstract：:Nowadays, risk of transfusion-transmitted infection has been substantially minimized by stringent donor eligibility screening and infectious disease testing. However, we report an interdiction of a blood donation containing varicella-zoster virus (VZV) by donor self-reporting of chickenpox. The donor developed varicel...

journal_title：Vox sanguinis

authors： Chan HM,Ho PL,Chan KH,Lin CK,Lee CK

更新日期：2013-04-01 00:00:00

abstract：:The effect of gamma irradiation on HIV and plasma coagulation factors F VIII:C, F VIII:vWF and FIX was studied. Donor plasma was harvested from single donations, frozen and irradiated in the frozen state at target doses from 0 to 40 kGy (0-4 mRad). HIV was inoculated into human plasma and irradiated in a similar manne...

journal_title：Vox sanguinis

authors： Kitchen AD,Mann GF,Harrison JF,Zuckerman AJ

更新日期：1989-01-01 00:00:00

abstract：:The classic enzyme-linked antiglobulin test (ELAT) used to detect and quantify the amount of IgG antibodies on red blood cells (RBC) is sensitive to hemolysis and erythrocyte enzymatic activities. We describe a new ELAT by using glucose oxidase (GO) linked to antihuman IgG. The optical density base line of GO-ELAT, al...

journal_title：Vox sanguinis

authors： Rigal D,Monestier M,Lafont S,Raffin T,Got A,Meyer F,Jouvenceaux A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:White blood cell (WBC) fragments in platelet concentrates (PCs) may induce allo-immunization in the recipient. MATERIALS AND METHODS:As the level of WBC fragments can differ between PCs produced using different methods, we compared PCs prepared by using the buffy-coat method (BC-PCs) in plasm...

journal_title：Vox sanguinis

authors： Dijkstra-Tiekstra MJ,van der Schoot CE,Pietersz RN,Reesink HW

更新日期：2005-05-01 00:00:00

abstract：:Anti-Vw detecting an antigen on Miltenberger I (Mi I) variant glycophorin A (GPA) has rarely been reported as a cause of hemolytic disease of the newborn (HDN). We report an infant with severe HDN due to anti-Vw. Examination of the Vw+ erythrocytes of the father and paternal grandmother by sodium dodecylsulphate polya...

journal_title：Vox sanguinis

authors： Rearden A,Frandson S,Carry JB

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Human monoclonal antibodies have been produced against various Rh antigens. We report here the production of another one against Rh C and the first such antibody against Rh CW. MATERIALS AND METHODS:Two heterohybridomas secreting IgG human monoclonal antibodies against Rh CW and Rh C (MS-353 ...

journal_title：Vox sanguinis

authors： Thorpe SJ,Boult CE,Thompson KM

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Recombinant activated factor VII (rFVIIa, NovoSeven) has been used off-label for various conditions. A protocol for its use in acute, uncontrolled life-threatening bleeding, was devised and employed. A haematologist/transfusion specialist was assigned as a member of the team. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Mayo A,Misgav M,Kluger Y,Geenberg R,Pauzner D,Klausner J,Ben-Tal O

更新日期：2004-07-01 00:00:00

abstract：:Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th week of gestation and was intensively performed 93 times up to the 35th week. The volu...

journal_title：Vox sanguinis

authors： Yoshida H,Ito K,Emi N,Kanzaki H,Matsuura S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:With traditional techniques the thawing time for fresh-frozen plasma (FFP) is about 20-30 min. A new technology using radio waves, radio wave thawing device (RTD), was applied for thawing FFP. With this technology the thawing time can substantially be reduced. The new technique was compared to...

journal_title：Vox sanguinis

authors： Boström F,Ekemar L,Olsson D,Egberg N,Lundahl J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:HPA-1a antibodies account for 70-80% of cases of fetal-neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians. However, numerous workshops have demonstrated variability in their detection. We recently showed that exposure of αIIbβ3 to ethylene diamine tetraacetic acid (EDTA) affected bindi...

journal_title：Vox sanguinis

authors： Allen DL,Metcalfe P,Kaplan C,Kekomaki R,de Haas M,Yusuf R,Ouwehand WH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Recent changes have resulted in the loss of 4% of the donor panel in the Republic of Ireland and 3% in Northern Ireland. In order to increase the number of donors in these two regions, it is important that transfusion service providers explore and understand the reasons, which prevent individuals from donati...

journal_title：Vox sanguinis

authors： Harrington M,Sweeney MR,Bailie K,Morris K,Kennedy A,Boilson A,O'Riordan J,Staines A

更新日期：2007-05-01 00:00:00

abstract：:A simple method, based on ethanol fractionation, for the preparation of highly purified human serum albumin with a higher yield than that of the conventional ethanol procedures is described. It consists of two purification steps, namely, precipitation of most of the other plasma proteins from a 3-fold diluted plasma w...

journal_title：Vox sanguinis

authors： Hao Y

更新日期：1979-01-01 00:00:00

abstract：:Anti-Sdx is an IgM complement-binding autoantibody that defines a red cell antigen which is independent of I, i, Sp1 (Pr) and Gd. Hemagglutination by the antibody is unusually sensitive to variation in pH, salt, or other charged molecular species. The antibody is inhibited by urine from Sd(a+) persons, but inhibition ...

journal_title：Vox sanguinis

authors： Bass LS,Rao AH,Goldstein J,Marsh WL

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:One of the challenges surrounding blood component administration is the determination of an appropriate rate of infusion. There are very few evidence-based guidelines available to guide healthcare providers looking for a 'standard' infusion rate for red blood cells (RBCs), plasma or platelets ...

journal_title：Vox sanguinis

authors： Gehrie EA,Hendrickson JE,Tormey CA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A patient transfused with two pooled platelet concentrates became breathless. Bilateral infiltrates were seen on chest X-ray. A diagnosis of transfusion-related acute lung injury (TRALI) was made. The patient received 100% oxygen and recovered after 5 days. MATERIALS AND METHODS:Antibody scre...

journal_title：Vox sanguinis

authors： Lucas G,Rogers S,Evans R,Hambley H,Win N

更新日期：2000-01-01 00:00:00

abstract：:Forty-six subjects (44 HIV antibody-positive) with some degree of immune deficiency (at least TH/TS ratio below 1) were randomly distributed into 4 treatment groups. Each group was assigned to 1 of 4 products to be used exclusively for a 1-year period: 1 concentrate was of intermediate purity and not heat-treated, and...

journal_title：Vox sanguinis

authors： Allain JP,Frommel D,Bosser C,Gazengel C,Larrieu MJ,Sultan Y

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In a preliminary study, the presence of potassium and magnesium in a modified synthetic medium (PAS-III) was found to have a significant influence on platelet metabolism (using apheresis-derived, as well as buffy-coat-derived platelets) when compared with standard PAS-III. The differences incl...

journal_title：Vox sanguinis

authors： Gulliksson H,AuBuchon JP,Cardigan R,van der Meer PF,Murphy S,Prowse C,Richter E,Ringwald J,Smacchia C,Slichter S,de Wildt-Eggen J

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Immune haemolysis in liver transplant (LT) can occur due to autoantibodies and alloantibodies. The aim of this study was to evaluate the prevalence and risk factors for immune haemolysis in LT. METHODS:A total of 175 consecutive patients were included. Multiorgan recipients were excluded. Samples, from befo...

journal_title：Vox sanguinis

authors： Brunetta DM,de Barros Carlos LM,Da Silva VFP,de Oliveira Alves TM,Macedo ÊS,Coelho GR,Vasconcelos JBM,De Francesco Daher E,Garcia JHP

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In previous studies, we found that platelet microparticles (PMPs) bind to cord blood (CB) CD34+ cells and transfer adhesion molecules to them, which enhances their engraftment. Before applying this phenomenon in actual transplants, we investigated the effect of PMPs on cryopreserved CD34+ cell...

journal_title：Vox sanguinis

authors： Liu B,Chen JS,Cao M,Gu SL,Liao C,Li DZ,Zhong HZ

更新日期：2004-08-01 00:00:00

abstract：:Idiopathic analbuminemia was fortuitously detected in a 30-year-old Italian woman. No associated disease condition could be revealed in this patient, the only consistent finding being a slight tendency to develop ankle edema. Asthenia and a moderate hypotension were also recorded. Trace amounts (5.2 mg/100 ml) of seru...

journal_title：Vox sanguinis

authors： Dammacco F,Miglietta A,D'Addabbo A,Fratello A,Moschetta R,Bonomo L

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:For some unknown reason humans may 'spontaneously' produce high amounts of neutralizing autoantibodies to a number of growth factors and cytokines. Reaching a certain high level the antibodies render the person cytokine deficient, mostly without overt clinical manifestations. The autoantibodies in question a...

journal_title：Vox sanguinis

authors： Hansen MB,Galle P,Salomo M,Svenson M,Dickmeiss E,Gimsing P

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous studies with p38MAPK inhibitors at room temperature demonstrated that they improve a large number of platelet storage parameters, but cannot substantially inhibit p38MAPK activation nor protect against widespread decrements in platelet quality parameters during 4 °C storage. In this s...

journal_title：Vox sanguinis

authors： Wagner SJ,Skripchenko A,Seetharaman S,Kurtz J

更新日期：2015-04-01 00:00:00

abstract：:Hepatitis A virus (HAV) infections have been reported among hemophiliacs who received factor VIII concentrates which had been purified by ion-exchange chromatography and treated by the solvent detergent (SD) method. Since the virus inactivation procedure of our manufacturing process is heat treatment of the stabilized...

journal_title：Vox sanguinis

authors： Hilfenhaus J,Nowak T

更新日期：1994-01-01 00:00:00

abstract：:Significantly more peripheral blood mononuclear cells (PBM) from 39 patients with lymphoma (p less than 0.001), myeloma (p less than 0.001), or leukemia (p less than 0.001-0.025) bind transferrin (Trf) than those of 23 normals. That Trf was bound to a receptor on these cells was shown by the inhibition of these cells ...

journal_title：Vox sanguinis

authors： Yeh CJ,Taylor CG,Faulk WP

更新日期：1984-01-01 00:00:00