A family with allo-immune neonatal neutropenia: group-specific pathogenicity of maternal antibodies.

abstract：BACKGROUND AND OBJECTIVES:There are conflicting data regarding the therapeutic efficacy of platelets inactivated using amotosalen and ultraviolet A light. We have performed a meta-analysis to summarize the results of different randomized controlled trials (RCT). MATERIALS AND METHODS:Five RCTs reported through March 2...

journal_title：Vox sanguinis

authors： Cid J,Escolar G,Lozano M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:We have developed and optimised a new flow-cytometric method for the measurement of the Fc function of intravenous immunoglobulin (IVIg) preparations, which is important in predicting the effector function of immunoglobulin (Ig) in such preparations. MATERIALS AND METHODS:Ig was bound to a monocytic cell li...

journal_title：Vox sanguinis

authors： Ramasamy I,Tran E,Charnock A,Farrugia A

更新日期：2000-01-01 00:00:00

abstract：:Blood transfusions are associated with clinical phenomena which are attributable to immune suppression. Since suppression of immune function is associated with a high risk of spontaneous malignancies, we studied T cell subsets and natural killer (NK) cytotoxicity in colorectal cancer patients and correlated the result...

journal_title：Vox sanguinis

authors： Tartter PI,Steinberg B,Barron DM,Martinelli G

更新日期：1989-01-01 00:00:00

abstract：:Pst I endonuclease fragment length polymorphism of the antithrombin III probe was studied in a French population. Among 25 subjects tested, 15 were found heterozygous at the Pst I site, so that this polymorphism might serve as a useful markers of antithrombin III gene in families with antithrombin III deficiency. ...

journal_title：Vox sanguinis

authors： Le Paslier D,Rochu D,Lucotte G

更新日期：1985-01-01 00:00:00

abstract：:The classic enzyme-linked antiglobulin test (ELAT) used to detect and quantify the amount of IgG antibodies on red blood cells (RBC) is sensitive to hemolysis and erythrocyte enzymatic activities. We describe a new ELAT by using glucose oxidase (GO) linked to antihuman IgG. The optical density base line of GO-ELAT, al...

journal_title：Vox sanguinis

authors： Rigal D,Monestier M,Lafont S,Raffin T,Got A,Meyer F,Jouvenceaux A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Recent changes have resulted in the loss of 4% of the donor panel in the Republic of Ireland and 3% in Northern Ireland. In order to increase the number of donors in these two regions, it is important that transfusion service providers explore and understand the reasons, which prevent individuals from donati...

journal_title：Vox sanguinis

authors： Harrington M,Sweeney MR,Bailie K,Morris K,Kennedy A,Boilson A,O'Riordan J,Staines A

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:IgG subclasses of anti-D seem to play some role in hemolytic disease of the newborn, but there has been disagreement as to its exact nature. The aim of our study was to evaluate a new technique for IgG subclassing of anti-D and to compare it to an established test. MATERIALS AND METHODS:In 31...

journal_title：Vox sanguinis

authors： Palfi M,Hildén JO

更新日期：1997-01-01 00:00:00

abstract：:In a prospective study of 50 recipients of HBsAg-negative blood who had undergone cardiac surgery, 4 (8%) developed acute non-A, non-B hepatitis. The patients who developed hepatitis had received significantly more units of blood or blood products than the patients who had no hepatitis. The incubation period of the di...

journal_title：Vox sanguinis

authors： Tur-Kaspa R,Shimon DV,Shalit M,Adler R,Shraga S,Manny N,Morag A,Eliakim M

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. MATERIALS AND METHODS:The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelet...

journal_title：Vox sanguinis

authors： Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cold-stored platelets may be an alternative to conventional room temperature (RT) storage. However, cold-stored platelets are cleared more rapidly from circulation, reducing their suitability for prophylactic transfusion. To minimise wastage, it may be beneficial to store platelets conventiona...

journal_title：Vox sanguinis

authors： Wood B,Johnson L,Hyland RA,Marks DC

更新日期：2018-04-06 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Warm autoimmune hemolytic anemia (AIHA) is a condition in which peripheral red blood cell (RBC) destruction is induced by the presence of an autoantibody. Pure red cell aplasia (PRCA) represents an isolated process of decreased erythropoiesis. The combination of both is quite rare, with a very ...

journal_title：Vox sanguinis

authors： Zeidman A,Fradin Z,Barac Y,Bendayan D,Mittelman M,Orlin J

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：:A non-blow-molded LE-2 polyolefin (PO) container was developed to store single-donor apheresis platelet concentrates (PCs) processed by the Haemonetics Plasma Collecting System (PCS) at 22 degrees C for over 1 day. We molded PO containers with heat-sealing of light-weight polymer alloy films with a thickness of 0.25 m...

journal_title：Vox sanguinis

authors： Shimizu T,Kouketsu K,Kamiya T,Futagawa H,Hirose S

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A major requirement of a hepatitis C virus (HCV) RNA nucleic acid amplification technology (NAT) assay validation is the ability of the assay to detect the six major genotypes of HCV with equivalent sensitivities. The aim of this study was to characterize and calibrate an HCV genotype panel fo...

journal_title：Vox sanguinis

authors： Saldanha J,Heath A,Collaborative Study Group.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Warm autoantibodies (WAA) are antibodies that react with an antigen on a patient's own red-blood-cells and can complicate compatibility testing whether or not they cause clinical haemolysis. The goal of this study was to understand the overall prevalence of WAA, the risk of RBC alloimmunization and determine...

journal_title：Vox sanguinis

authors： Delaney M,Apelseth TO,Bonet Bub C,Cohn CS,Dunbar NM,Mauro Kutner J,Murphy M,Perelman I,Selleng K,Staves J,Wendel S,Ziman A,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2020-08-01 00:00:00

abstract：:Bacterial contamination of platelet concentrates poses a major post-transfusion infectious risk. This study was aimed at evaluating the efficacy of the BacTx(®) assay (Immunetics Inc.) for bacterial detection in leucocyte-reduced buffy coat platelet pools and for its sensitivity in detecting clinical isolates, includi...

journal_title：Vox sanguinis

authors： Ramirez-Arcos S,Kou Y,Perkins H

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Gene conversion events between GYPA and GYPB or GYPA and GYPE are facilitated by the close chromosomal proximity and high degree of sequence homology and can lead to the formation of GP hybrid genes. Discrepant results between blood group genotyping and haemagglutination in 22 random blood don...

journal_title：Vox sanguinis

authors： Polin H,Danzer M,Reiter A,Brisner M,Gaszner W,Weinberger J,Gabriel C

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to analyse the platelet function, over a 5-day time-period, of apheresis-derived platelet concentrates obtained from smokers and non-smokers. MATERIALS AND METHODS:Smoker and non-smoker plateletpheresis products were investigated on days 1, 3 and 5 of storage. Recept...

journal_title：Vox sanguinis

authors： Scheinichen D,Heuft HG,Renken C,Jüttner B,Jaeger K,Schürholz T,Blasczyk R,Piepenbrock S,Elsner HA

更新日期：2004-05-01 00:00:00

abstract：:Activated protein C (APC) is a highly specific serine proteinase which functions as an important naturally occurring antithrombotic enzyme. APC also has anti-inflammatory properties. We have developed a large-scale process for the production of APC for therapeutic use starting with cryoprecipitate-poor human plasma. T...

journal_title：Vox sanguinis

authors： Orthner CL,Ralston AH,Gee D,Kent R,Kolen B,McGriff JD,Drohan WN

更新日期：1995-01-01 00:00:00

abstract：:Alloimmune neonatal thrombocytopenia (ANT) may cause intracranial haemorrhage in utero as well as at delivery. Recent management has concentrated on attempts to minimise fetal thrombocytopenia and prevent its complications. This report describes further experience with the use of repeated intravascular transfusions of...

journal_title：Vox sanguinis

authors： Murphy MF,Pullon HW,Metcalfe P,Chapman JF,Jenkins E,Waters AH,Nicolaides KH,Mibashan RS

更新日期：1990-01-01 00:00:00

abstract：:Two batches of heat-treated factor VIII concentrate were found to contain anti-HIV-positive plasma donations. The batches were dry-heat-treated at 68 degrees C for 2 and 24 h, respectively. No HIV seroconversions occurred in 13 susceptible haemophiliacs receiving a total of 540 bottles of these factor VIII preparation...

journal_title：Vox sanguinis

authors： Cuthbert RJ,Ludlam CA,Brookes E,McClelland DB

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transfusion is associated with a risk of infection and alloimmunization. Pathogen reduction using riboflavin and UV light (Mirasol treatment) inactivates pathogens and leucocytes. With increasing adoption of the technology in clinical use, regulatory agencies have recommended the introduction ...

journal_title：Vox sanguinis

authors： Bakkour S,Chafets DM,Wen L,van der Meer PF,Mundt JM,Marschner S,Goodrich RP,Busch MP,Lee TH

更新日期：2014-11-01 00:00:00

abstract：:Blood group B-gene-specified alpha-galactosyltransferase was determined in serums and erythrocyte membranes of several related persons with Bm phenotypes. The level of this enzyme in serums was similar to, but in erythrocyte membranes much lower than that found in normal B and AB persons. ...

journal_title：Vox sanguinis

authors： Kościelak J,Pacuszka T,Dzierzkowa-Borodej W

更新日期：1976-01-01 00:00:00

abstract：:Hepatitis E is considered an emerging disease that may be a threat in both developing and industrialized countries all over the world. The risk of chronic hepatitis E virus infection is higher among immunocompromised patients. This study aimed to assess the status of hepatitis E infection in patients with transfusion-...

journal_title：Vox sanguinis

authors： Klonizakis P,Gioula G,Exindari M,Apostolou C,Kotsiafti A,Vlachaki E

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several pathogen inactivation methods currently applied to therapeutic plasma may result in products with different hemostatic properties. This study aims at evaluating and comparing the hemostatic potential of different therapeutic plasma preparations currently available in France. MATERIALS...

journal_title：Vox sanguinis

authors： Hacquard M,Lecompte T,Belcour B,Geschier C,Jacquot C,Jacquot E,Schneider T

更新日期：2012-05-01 00:00:00

abstract：:One of the most controversial policies in blood transfusion worldwide is the permanent deferral from donating blood of men with sexual contacts to other men (MSM). This policy was implemented for safety reasons as sex between men is known to be a high risk factor for acquiring severe infectious diseases transmissible ...

journal_title：Vox sanguinis

authors： Offergeld R,Kamp C,Heiden M,Norda R,Behr-Gross ME

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In a preliminary study, the presence of potassium and magnesium in a modified synthetic medium (PAS-III) was found to have a significant influence on platelet metabolism (using apheresis-derived, as well as buffy-coat-derived platelets) when compared with standard PAS-III. The differences incl...

journal_title：Vox sanguinis

authors： Gulliksson H,AuBuchon JP,Cardigan R,van der Meer PF,Murphy S,Prowse C,Richter E,Ringwald J,Smacchia C,Slichter S,de Wildt-Eggen J

更新日期：2003-10-01 00:00:00

abstract：:K12 is a high-prevalence antigen, with no known antithetical partner, that is associated with the Kell blood group system. We report studies on the 5th propositus (MS) with the K:-12 phenotype and the second case to show that the K12 is inherited. The anti-K12 in his serum did not destroy antigen-positive incompatible...

journal_title：Vox sanguinis

authors： Reid ME,Oyen R,Redman CM,Gillespie G,Jones J,Eckrich R

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study. METHODS:The progression to AIDS in relation to type of haemophilia,...

journal_title：Vox sanguinis

authors： Roosendaal G,van der Schouw Y,Mauser-Bunschoten E,Borleffs J,van den Berg H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Fever is described in transfusion-associated circulatory overload (TACO), reflecting either comprehensive haemovigilance or an inflammatory pathobiology (such as congestion-associated atheroma disruptions). METHODS:Hospital haemovigilance data (1/1/2010-31/12/2012) were reviewed for TACO cases (frequency an...

journal_title：Vox sanguinis

authors： Parmar N,Pendergrast J,Lieberman L,Lin Y,Callum J,Cserti-Gazdewich C

更新日期：2017-01-01 00:00:00