K12 is located on the Kell blood group protein in proximity to K/k and Jsa/Jsb.

abstract：BACKGROUND AND OBJECTIVES:B subgroups are rare and the genetic analysis reported to date has been limited. MATERIALS AND METHODS:Serological and molecular investigations were performed in blood from a B-subgroup donor. RESULTS:Red cells did not react with anti-B and anti-AB reagents. However, cells absorbed anti-B. R...

journal_title：Vox sanguinis

authors： Sousa N,Anicchino-Bizzacchi JM,Leite EM,Locatelli MF,Albuquerque D,Costa FF,Barjas-Castro ML

更新日期：2005-01-01 00:00:00

abstract：:The storage of fresh frozen plasma (FFP) for short periods at -20 degrees C for 6 weeks, -30 degrees C for 12 weeks, or -40 degrees C for 12 weeks, did not result in significant deterioration in factor VIII: coagulant (factor VIII:C) activity in the primary packs. In studies examining whether plasma segments could be ...

journal_title：Vox sanguinis

authors： Ofosu FA,Blajchman MA,Kaegi A,Turc JM

更新日期：1985-01-01 00:00:00

abstract：:A group B recipient of a group 0 kidney developed severe intravascular haemolysis due to the formation of anti-B. Immunoglobulin allotyping of donor serum, recipient serum and 'unexpected' anti-B antibody showed the antibody to be of donor origin. The patient and donor genotypes were Gm 3;5/3;5 and Gm 1,2;21/1;21, res...

journal_title：Vox sanguinis

authors： Orchard J,Young NT,Smith C,Thomas S,Darke C

更新日期：1990-01-01 00:00:00

abstract：:The thermal stabilization of human albumin by caprylate (CA) and acetyltryptophanate (AT) was studied by monitoring the formation of albumin polymer (defined as species larger than dimer) on the basis of its molecular size as well as its characteristic migration as alpha-globulin. Heating 5% protein solutions of purif...

journal_title：Vox sanguinis

authors： Yu MW,Finlayson JS

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Staphylococcus epidermidis is a predominant contaminant of platelet concentrates (PCs), outcompeting other skin flora bacteria such as Staphylococcus capitis. The accumulation-associated protein (Aap), encoded by the aap gene, is involved in formation of bacterial aggregates (biofilms) in S. e...

journal_title：Vox sanguinis

authors： Alabdullatif M,Ramirez-Arcos S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:New CD36 mutations are constantly being identified, although no study has specifically targeted a Taiwanese population. CD36 deficiency can result in dyslipid state and slow clearance of chylomicron. This could be linked to more frequent lipemic donations. STUDY DESIGN AND METHODS:We used flow cytometric me...

journal_title：Vox sanguinis

authors： Lo SC,Lin KH,Hsieh HH,Lin DT,Hu CY

更新日期：2016-04-01 00:00:00

abstract：:Experiments have shown that suitably diluted, unpurified IgA paraprotein sera can be substituted for chemically purified IgA proteins in the passive haemagglutination test for the detection of anti-IgA antibodies. The substitution of unpurified IgA paraprotein was made possible by the enhanced serological activity obt...

journal_title：Vox sanguinis

authors： Hunt A,Reed M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Since July 1 1999, four laboratories in the Netherlands have been routinely screening plasma minipools for the release of labile blood components utilizing hepatitis C virus nucleic acid amplification technology (HCV NAT). This report describes the performance evaluation of the HCV NAT method ...

journal_title：Vox sanguinis

authors： Cuijpers HT,Molijn MH,Bos HJ,Peeters AP,van der Poel CL,Lelie PN

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study was undertaken to provide denominator data relating to the timing and location of transfusion, to support interpretation of reports of incorrect blood component transfused (IBCT) events to the UK Serious Hazards of Transfusion (SHOT) scheme. MATERIALS AND METHODS:The study was carr...

journal_title：Vox sanguinis

authors： Tinegate HN,Thompson CL,Jones H,Stainsby D

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In a preliminary study, the presence of potassium and magnesium in a modified synthetic medium (PAS-III) was found to have a significant influence on platelet metabolism (using apheresis-derived, as well as buffy-coat-derived platelets) when compared with standard PAS-III. The differences incl...

journal_title：Vox sanguinis

authors： Gulliksson H,AuBuchon JP,Cardigan R,van der Meer PF,Murphy S,Prowse C,Richter E,Ringwald J,Smacchia C,Slichter S,de Wildt-Eggen J

更新日期：2003-10-01 00:00:00

abstract：:We investigated the effects of gravitational force and three different plastic formulations of the storage bags on the quality of stored platelets by measuring the changes in platelet-associated immunoglobulin G (IgG) and two antigenic markers of the third component of human complement (C3), C3d and C3c. Pooled platel...

journal_title：Vox sanguinis

authors： Szymanski IO,Odgren PR,Teno RA,Jacobson MS,Surgenor DM

更新日期：1989-01-01 00:00:00

abstract：:Platelet antibodies were looked for in 47 patients with autoimmune thrombocytopenia using a modification of the enzyme-linked assay previously described. Surface-bound antibodies measured as increased platelet-associated IgG were found in 32 (68%) of the patients. After incubation in test sera, the platelet-associated...

journal_title：Vox sanguinis

authors： Hegde UM,Bowes A,Powell DK,Joyner MV

更新日期：1981-11-01 00:00:00

abstract：:Serum IgE was determined by radioimmunoassay in 28 subjects affected by homozygous beta thalassemia (14 males and 14 females, aged 3-19 years, mean age 7 +/- 5.6 years). They were given transfusions with packed red cells and chelant therapy. Blood samples were taken just before a transfusion (basal value) and at 10-da...

journal_title：Vox sanguinis

authors： La Rosa M,Pavone L,Musumeci S,Mollica F,Ronchetti R

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Fetal RHD genotyping of cell-free maternal plasma DNA from RhD negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment worksho...

journal_title：Vox sanguinis

authors： Clausen FB,Hellberg Å

更新日期：2020-07-01 00:00:00

abstract：:Recessively inherited ovalocytosis in coastal Melanesians is associated with widespread, but selective, depression of blood group antigens in homozygotes, who comprise about 15% of these populations. It is suggested that a membrane anomaly exists, and that the series of depressed determinants all depend, for their ful...

journal_title：Vox sanguinis

authors： Booth PB,Serjeantson S,Woodfield DG,Amato D

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This report describes a method for estimating the risk of transfusion-transmitted HBV infection attributable to blood components from donors with occult hepatitis B virus infection (OBI) applicable where universal anti-HBc screening is not performed. MATERIALS AND METHODS:In the context of pa...

journal_title：Vox sanguinis

authors： Seed CR,Kiely P

更新日期：2013-11-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Blood transfusions can transmit parasitic infections, such as those caused by Plasmodium (malaria), Trypanosoma cruzi (Chagas' disease), and Babesia (babesiosis). A higher degree of blood transfusion safety would be reached if methods were available for inactivating such parasites. MATERIALS ...

journal_title：Vox sanguinis

authors： Grellier P,Santus R,Mouray E,Agmon V,Mazière JC,Rigomier D,Dagan A,Gatt S,Schrével J

更新日期：1997-01-01 00:00:00

abstract：:Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 Amazon...

journal_title：Vox sanguinis

authors： Franco RF,Simões BP,Guerreiro JF,Santos SE,Zago MA

更新日期：1994-01-01 00:00:00

abstract：:An example of a cold-reacting IgM anti-K2 is described. The patient has a history of blood transfusion and two pregnancies. It is, therefore, not possible to differentiate between natural occurrence or immune stimulation as an explanation of this antibody's presence. In 1966, Thomas and Konugres reported an unusual ex...

journal_title：Vox sanguinis

authors： Dinning G,Doughty RW,Collins AK

更新日期：1985-01-01 00:00:00

abstract：:Hepatitis B virus infectivity can be removed from human plasma used to prepare a gamma-globulin product by ion-exchange chromatography with commercially available resins. A pooled human plasma sample free of hepatitis markers was contaminated with 10,000 chimpanzee infectious doses of hepatitis B virus per milliliter ...

journal_title：Vox sanguinis

authors： Zolton RP,Padvelskis JV,Kaplan PM

更新日期：1985-01-01 00:00:00

abstract：INTRODUCTION:Bleeding is increasingly considered an important end point in clinical platelet transfusion studies. Accurate recording and adjudication into well-defined bleeding grades, however, remains a major challenge. METHODS:We developed a computer algorithm for automatic adjudication. The algorithm's results were...

journal_title：Vox sanguinis

authors： Middelburg RA,Ypma PF,van der Meer PF,van Wordragen-Vlaswinkel RJ,Eissen O,Kerkhoffs JL

更新日期：2013-08-01 00:00:00

abstract：:The number of Lub antigen sites on the human erythrocyte membrane, as recognised by the murine monoclonal antibody BRIC-108, has been determined. The number of antibody molecules bound per cell on one example of cells of the phenotype Lu(a-b-) with recessive inheritance was an average of around 200 in replicate determ...

journal_title：Vox sanguinis

authors： Merry AH,Gardner B,Parsons SF,Anstee DJ

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The supply of phenotyped red blood cells (RBC) for patients with several RBC antibodies presents a difficult task to hospital blood banks and regional blood centers. The aim of this study was to establish a low-cost typing system to allow extensive phenotyping of regular blood donors for clini...

journal_title：Vox sanguinis

authors： Llopis F,Carbonell-Uberos F,Montero MC,Bonanad S,Planelles MD,Plasencia I,Riol C,Planells T,Carrillo C,De Miguel A

更新日期：1999-01-01 00:00:00

abstract：:Metabolic properties of standard gamma globulin (St-GG) and of several gamma globulin (GG) preparations for intravenous use were analyzed in radioactive tracer studies. The in vivo behaviour of St-GG was investigated in 16 probands and found to be comparable to that of normal IgG. The kinetics of the resorption of St-...

journal_title：Vox sanguinis

authors： Morell A,Schürch B,Ryser D,Hofer F,Skvaril F,Barandun S

更新日期：1980-01-01 00:00:00

abstract：:The stabilization of human immunoglobulin (IgG) by chemically modified gelatins (Haemaccel and Gelofusine) was investigated. The gelatins prevented IgG from aggregation induced by exposure to interfaces and lyophilization. The stabilization effects of the gelatins were significantly larger than those of amino acids or...

journal_title：Vox sanguinis

authors： Tomono T,Ikeda K,Suzuki T

更新日期：1986-01-01 00:00:00

abstract：:In this prospective study, 26 consecutive patients being treated for haematological malignancies receiving standard (i.e. non-leucocyte-depleted) blood components were observed for the development of refractoriness to platelet transfusions. One hundred and sixteen of the 266 (44%) platelet transfusions failed to produ...

journal_title：Vox sanguinis

authors： Doughty HA,Murphy MF,Metcalfe P,Rohatiner AZ,Lister TA,Waters AH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A major requirement of a hepatitis C virus (HCV) RNA nucleic acid amplification technology (NAT) assay validation is the ability of the assay to detect the six major genotypes of HCV with equivalent sensitivities. The aim of this study was to characterize and calibrate an HCV genotype panel fo...

journal_title：Vox sanguinis

authors： Saldanha J,Heath A,Collaborative Study Group.

更新日期：2003-01-01 00:00:00

abstract：:Although we still do not know enough about the influence of anaemia and transfusion on outcomes for the surgical patient, it is possible to develop a general consensus about many aspects of management. A quality programme to improve consistency of practice in these consensus areas is feasible. (Table 6) This should be...

journal_title：Vox sanguinis

authors： McClelland B

更新日期：1998-01-01 00:00:00