Abstract:
:Significantly more peripheral blood mononuclear cells (PBM) from 39 patients with lymphoma (p less than 0.001), myeloma (p less than 0.001), or leukemia (p less than 0.001-0.025) bind transferrin (Trf) than those of 23 normals. That Trf was bound to a receptor on these cells was shown by the inhibition of these cells bound to 125I-Trf with unlabeled Trf. The paucity of Trf receptors on PBM from normals and their presence on diseased cells prompt a suggestion that Trf receptors may offer a useful approach to the diagnosis and possible treatment of some blood dyscrasias.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Yeh CJ,Taylor CG,Faulk WPdoi
10.1111/j.1423-0410.1984.tb00078.xsubject
Has Abstractpub_date
1984-01-01 00:00:00pages
217-23issue
4eissn
0042-9007issn
1423-0410journal_volume
46pub_type
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