Characterization of plasma protein activity in riboflavin and UV light-treated fresh frozen plasma during 2 years of storage at -30 degrees C.

abstract：:To maximize the availability of platelet concentrates (PC) and minimize their outdate, competing criteria, a computer simulation model of platelet production and distribution was developed. Based on 2 years of actual platelet orders placed with a regional blood center, the simulation program generated daily platelet o...

journal_title：Vox sanguinis

authors： Katz AJ,Carter CW,Saxton P,Blutt J,Kakaiya RM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A dramatic decrease in the level of 2,3-diphosphoglycerate (2,3-DPG) takes place during the storage of whole blood (WB) in CPDA (citrate-phosphate-dextrose-adenine) and a similar decrease occurs during the storage of red blood cells (RBCs) in SAGM (saline-adenine-glucose-mannitol). The aim of ...

journal_title：Vox sanguinis

authors： Kurup PA,Arun P,Gayathri NS,Dhanya CR,Indu AR

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The occurrence of thromboembolic events (TEEs) with intravenous immunoglobulin lots (IVIGs) raised the question of the causative agent for these adverse events. We investigated the predominant plasma proteases in 19 IVIG lots from five manufacturers including three lots associated with adverse...

journal_title：Vox sanguinis

authors： Etscheid M,Breitner-Ruddock S,Gross S,Hunfeld A,Seitz R,Dodt J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Our post-thaw cell recovery rates differed substantially in interlaboratory comparisons of identical samples, potentially due to different temperatures during cell staining. MATERIALS AND METHODS:Viable CD34(+) cells and leucocyte (WBC) subtypes were quantified by multiparameter single-platfo...

journal_title：Vox sanguinis

authors： Fritsch G,Frank N,Dmytrus J,Frech C,Pichler H,Witt V,Geyeregger R,Scharner D,Trbojevic D,Zipperer E,Printz D,Worel N

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pr1,2,3, PrM, Sa and Sia-l1, -b1, -lb1 are sialic acid (NeuNAc)-dependent antigens recognized by human cold agglutinins. Pr and Sa antigens are the O-glycans of glycophorins containing alpha 2,3NeuNAc (to galactose) and/or alpha 2,6NeuNAc (to galactosamine). The antigens of the Sia-l1, -b1, -l...

journal_title：Vox sanguinis

authors： Roelcke D,Hack H,Kreft H,Gross HJ

更新日期：1998-01-01 00:00:00

abstract：:2,140 pregnant Sudanese women attending the antenatal clinic in Omdurman Maternity Hospital during the period November 1975 to December 1976 had ABO and Rh typing performed. Their sera were also screened by a modified papain enzyme technique for the presence of atypical antibodies. The rate of Rhesus immunization, the...

journal_title：Vox sanguinis

authors： Abu-Sin AY,Ayoub M,Abdelrazig H

更新日期：1978-01-01 00:00:00

abstract：:Emerging data in animal models and humans suggest that pathogen-associated and damage-associated molecular patterns variably impact RBC alloantibody formation. In this study, we tested the hypothesis that vaccinations may enhance immune responses to transfused RBCs. The Pneumovax23 vaccine decreased the magnitude of a...

journal_title：Vox sanguinis

authors： Natarajan P,Santhanakrishnan M,Tormey CA,Hendrickson JE

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Practices in end-of-life platelet transfusions in haematologic malignancies are variable. Our aim was to describe the platelet transfusion burden and parameters linked to this indication in such a setting and thereby contribute to defining optimal practices. MATERIALS AND METHODS:From July 20...

journal_title：Vox sanguinis

authors： Moracchini J,Seigeot A,Angelot-Delettre F,Vienot A,Aubry R,Daguindau É,Deconinck E,Frache S,Tiberghien P

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The non-paired two-arm study compared the in vitro storage characteristics of platelets suspended as concentrates in either 100% plasma or a mixture of additive solution (SSP+™, MacoPharma, Mouveaux, France) and autologous plasma in a 70:30 ratio over a 14-day storage period. MATERIALS AND ME...

journal_title：Vox sanguinis

authors： Saunders C,Rowe G,Wilkins K,Holme S,Collins P

更新日期：2011-08-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-associated mortality. The inadvertent transfusion of neutrophil antibodies can cause pulmonary transfusion reactions and TRALI. However, not all patients transfused with neutrophil antibodies experience transfusion reactions. A 2...

journal_title：Vox sanguinis

authors： Muniz M,Sheldon S,Schuller RM,Young NS,Klein HG,Leitman SF,Stroncek DF

更新日期：2008-01-01 00:00:00

abstract：:Separable anti-T and anti-Tk lectins can be extracted from the seeds of Vicia hyrcanica. The anti-T lectin is similar to that of the peanut, Arachis hypogaea; the anti-Tk lectin compares favourably with that of Griffonia simplicifolia II. ...

journal_title：Vox sanguinis

authors： Liew YW,Bird GW

更新日期：1988-01-01 00:00:00

abstract：:Acute posttransfusion hepatitis C was reported in a recipient of 3 units of red cells. The recipient became acutely icteric 6 weeks after transfusion, and HCV infection was diagnosed. Stored serum samples of the 3 implicated donations, which were negative with ELISA-2, were retested by PCR and 3rd-generation antibody ...

journal_title：Vox sanguinis

authors： Vrielink H,van der Poel CL,Reesink HW,Zaaijer HL,Lelie PN

更新日期：1995-01-01 00:00:00

abstract：:Early and regular blood transfusion therapy in patients with homozygous beta-thalassaemia decreases the complications of severe anaemia and prolongs survival. In the long term, however, the beneficial effects of transfusions are limited by the organ damage resulting from iron overload, a consequence of the body's limi...

journal_title：Vox sanguinis

authors： Prati D

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Miltenberger subtype III (Mi.III, GP.Mur) is one of the most important red cell phenotypes in the fields of transfusion in South-East Asia. GP.Mur is believed to evolve from homologous gene recombination events between glycophorin A (GYPA) and glycophorin B (GYPB). GYP.Mur differs from GYPB in...

journal_title：Vox sanguinis

authors： Hsu K,Yao CC,Lin YC,Chang CL,Lee TY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Plasma exchange (PE) and immunoadsorption with the Immusorba TR-350 column (IA) are used to remove autoantibodies from plasma in acute neurological autoimmune disorders. The impact of IA on coagulation and on low molecular weight heparin (LMWH) levels in comparison with PE was investigated. P...

journal_title：Vox sanguinis

authors： Koessler J,Kobsar A,Kuhn S,Koessler A,Yilmaz P,Weinig E,Putz E,Boeck M,Klinker E

更新日期：2015-01-01 00:00:00

abstract：:The presence of IgM antibodies to human immunodeficiency virus 1 (HIV-1) was investigated in blood donor sera which were indeterminate in anti-HIV-1 IgG Western blot testing. In 7 of 173 instances out of approximately 1,000,000 blood donation sera with an isolated anti-p24 IgG produced an anti-gp41-45 IgM immunoblot r...

journal_title：Vox sanguinis

authors： Knüver-Hopf J,Heinze H,Lambrecht B,Mohr H,Beyer J,Schmitt H

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Parvovirus B19 (B19V) DNA seems to persist in the plasma of B19V-infected blood donors. The relevance of this for recipients of single-donor blood components is yet unclear. MATERIAL AND METHODS:We studied serial archive and follow-up samples from 75 B19V-infected blood donors to obtain more ...

journal_title：Vox sanguinis

authors： Juhl D,Görg S,Hennig H

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies to antigens in the Kell blood group system, especially anti-KEL1, are involved in both haemolytic disease of the newborn and foetus and haemolytic transfusion reactions. Correct typing results are important and discrepancies between serologic and genetic typing must be resolved. Her...

journal_title：Vox sanguinis

authors： Wester ES,Steffensen R,Ligthart PC,Vad J,de Haas M,Storry JR,Olsson ML

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The German Armed Forces Blood Service in Koblenz supplies red blood cell concentrates (RBCs) to military and civilian institutions at home and to field hospitals during peacekeeping operations abroad. During long-distance transport, blood products can be exposed to extreme environmental condit...

journal_title：Vox sanguinis

authors： Klose T,Borchert HH,Pruss A,Roth WK,Bohnen HR,Putzker M

更新日期：2010-07-01 00:00:00

abstract：:Pst I endonuclease fragment length polymorphism of the antithrombin III probe was studied in a French population. Among 25 subjects tested, 15 were found heterozygous at the Pst I site, so that this polymorphism might serve as a useful markers of antithrombin III gene in families with antithrombin III deficiency. ...

journal_title：Vox sanguinis

authors： Le Paslier D,Rochu D,Lucotte G

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Recent changes have resulted in the loss of 4% of the donor panel in the Republic of Ireland and 3% in Northern Ireland. In order to increase the number of donors in these two regions, it is important that transfusion service providers explore and understand the reasons, which prevent individuals from donati...

journal_title：Vox sanguinis

authors： Harrington M,Sweeney MR,Bailie K,Morris K,Kennedy A,Boilson A,O'Riordan J,Staines A

更新日期：2007-05-01 00:00:00

abstract：:63 Rh-negative male volunteers were immunized with D-positive red cells. 28 (44%) produced anti-D. To provide sustained levels of high concentration of anti-D, 18 of the 28 male volunteers have received repeated antigenic stimuli at individual intervals of 2-9 months. In all but 1 case the level of anti-D rose to betw...

journal_title：Vox sanguinis

authors： Eklund J

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:One of the challenges surrounding blood component administration is the determination of an appropriate rate of infusion. There are very few evidence-based guidelines available to guide healthcare providers looking for a 'standard' infusion rate for red blood cells (RBCs), plasma or platelets ...

journal_title：Vox sanguinis

authors： Gehrie EA,Hendrickson JE,Tormey CA

更新日期：2015-11-01 00:00:00

abstract：:We studied 684 sera obtained from 20 hemophilia patients with AIDS/AIDS-related complex (ARC), 89 asymptomatic HIV+, 76 HIV- hemophilia patients and 151 healthy controls for antibodies against recombinant CD4 (rCD4). Twenty-two percent of AIDS/ARC patients, 10% of asymptomatic HIV+ patients, 17% of HIV-patients, and 1...

journal_title：Vox sanguinis

authors： Daniel V,Weimer R,Zettlmeissl G,Langner K,Zimmermann R,Opelz G

更新日期：1992-01-01 00:00:00

abstract：:The domain specificity of anti-factor VIII (FVIII) inhibitor antibodies was determined in assays using FVIII domains generated by thrombin cleavage or expressed as recombinant polypeptides to neutralise the inhibitor. The results revealed the existence of three major types of inhibitors, and various combinations of th...

journal_title：Vox sanguinis

authors： Scandella D

更新日期：1999-01-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In order to preserve platelet concentrates (PCs) with high yields, a new polyolefin platelet storage container (PL 2410, 1.3L, Baxter, La Châtre, France) with increased gas permeability in combination with a larger surface area has been developed. The storage capacity was studied with platelet...

journal_title：Vox sanguinis

authors： de Wildt-Eggen J,Schrijver JG,Smid WM,Joie M,Bollinne V,Bins M

更新日期：1998-01-01 00:00:00

abstract：:A family is presented, in which the mother developed strong neutrophil granulocyte-specific antibodies with the specificity anti-NA. The first and third children, both NA1-positive, suffered from severe transient neonatal neutropenia, but the second child, NA1-negative, did not. Anti-NA1 antibodies were detectable in ...

journal_title：Vox sanguinis

authors： Verheugt FW,van Noord-Bokhorst JC,von dem Borne AE,Engelfriet CP

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hepcidin is the main hormone that regulates iron balance. Its lowering favours digestive iron absorption in cases of iron deficiency or enhanced erythropoiesis. The careful dosage of this small peptide promises new diagnostic and therapeutic strategies. Its measurement is progressively being v...

journal_title：Vox sanguinis

authors： Waldvogel S,Rochat B,Peduzzi D,Vaucher P,Tissot JD,Favrat B

更新日期：2016-02-01 00:00:00