Current concepts for quality assured long-distance transport of temperature-sensitive red blood cell concentrates.

abstract：BACKGROUND AND OBJECTIVES:Currently, plasma fractionation involves multiple processing steps using established methods such as ethanol precipitation and column chromatography. The known limitations associated with conventional purification techniques, combined with strict regulations on safety and high demand for parti...

journal_title：Vox sanguinis

authors： Li G,Stewart R,Conlan B,Gilbert A,Roeth P,Nair H

更新日期：2002-11-01 00:00:00

abstract：:The authors have studied the incidence of hepatitis associated antigen (HAA) and the homologous antibody in sera of patients with rheumatoid arthritis on the basis of (1) arthritis sometimes associated with viral hepatitis, (2) the possible infectious etiology of rheumatoid arthritis, and (3) observation on the possib...

journal_title：Vox sanguinis

authors： Marcolongo R,Debolini A

更新日期：1975-01-01 00:00:00

abstract：:Hepatitis E is considered an emerging disease that may be a threat in both developing and industrialized countries all over the world. The risk of chronic hepatitis E virus infection is higher among immunocompromised patients. This study aimed to assess the status of hepatitis E infection in patients with transfusion-...

journal_title：Vox sanguinis

authors： Klonizakis P,Gioula G,Exindari M,Apostolou C,Kotsiafti A,Vlachaki E

更新日期：2017-10-01 00:00:00

abstract：:To obtain red cell populations of increasing mean age erythropoiesis was arrested through continuous actinomycin treatment or maintained transfusion polycythemia in mice and rats respectively. The parameters studied included cell indices, enzyme activities and rheological characteristics. Further, the life-span of age...

journal_title：Vox sanguinis

authors： Ganzoni AM,Barras JP,Marti HR

更新日期：1976-01-01 00:00:00

abstract：:Plasma pools, prepared from time-expired blood stored in plastic packs, were analysed for DEHP content and levels ranging from 0.78 to 7.42 mh DEHP/100 ml plasma obtained. The DEHP content of the Cohn fractions prepared from such plasma pools was estimated. Only very low levels of DEHP were found in the four therapeut...

journal_title：Vox sanguinis

authors： Gilbo CM,Coles NW

更新日期：1975-01-01 00:00:00

abstract：:Little is known about the patient's reasons for participating in an autologous blood (AUB) collection program. We surveyed 110 AUB donors in our hospital-based collection program. Although fear of infection from an allogeneic blood transfusion was cited by 20% of AUB donors, 68.2% indicated that their physician's reco...

journal_title：Vox sanguinis

authors： Domen RE,Ribicki LA,Hoeltge GA

更新日期：1995-01-01 00:00:00

abstract：:Recently, the polymorphism of a new human platelet antigen, Ca/Tu, was shown to be derived from a G-A nucleotide substitution at base 1564 of GPIIIa cDNA, which leads to a single amino acid difference, Arg/Gln at amino acid 489 of GPIIIa. We developed a PCR-RFLP method to determine the genotypes of Ca/Tu and their fre...

journal_title：Vox sanguinis

authors： Tanaka S,Taniue A,Nagao N,Tomita T,Ohnoki S,Shibata H,Okubo Y,Yamaguchi H,Shibata Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Fever is described in transfusion-associated circulatory overload (TACO), reflecting either comprehensive haemovigilance or an inflammatory pathobiology (such as congestion-associated atheroma disruptions). METHODS:Hospital haemovigilance data (1/1/2010-31/12/2012) were reviewed for TACO cases (frequency an...

journal_title：Vox sanguinis

authors： Parmar N,Pendergrast J,Lieberman L,Lin Y,Callum J,Cserti-Gazdewich C

更新日期：2017-01-01 00:00:00

abstract：:Changes in metabolic and functional activity of platelets stored as platelet concentrates in plastic bags highly permeable to gases were investigated. The following parameters were measured daily: pH, pO2, pCO2, HCO3, glucose, lactic acid, lactic dehydrogenase, cellular ATP and platelet aggregation induced by differen...

journal_title：Vox sanguinis

authors： Fagiolo E,Lippa S,Mores N,Oradei A,Aureli V

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:In order to describe the progression of HIV disease in a cohort of Dutch HIV-1-infected patients with haemophilia and to study the influence of clinical and clotting factors, we performed a 15-year longitudinal clinical and laboratory study. METHODS:The progression to AIDS in relation to type of haemophilia,...

journal_title：Vox sanguinis

authors： Roosendaal G,van der Schouw Y,Mauser-Bunschoten E,Borleffs J,van den Berg H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:There have been recurrent shortages of group O blood due to insufficient inventory and use of group O blood in ABO non-identical recipients. We performed a 12-year retrospective study to determine utilization of group O Rh-positive and Rh-negative red blood cells (RBCs) by recipient ABO group. Reasons for tr...

journal_title：Vox sanguinis

authors： Barty RL,Pai M,Liu Y,Arnold DM,Cook RJ,Zeller MP,Heddle NM

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. MATERIALS AND METHODS:The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelet...

journal_title：Vox sanguinis

authors： Van Aelst B,Feys HB,Devloo R,Vanhoorelbeke K,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To determine the frequency of maternal-fetal hemorrhage at or above 1 microliter of maternal whole blood. METHODS:Seventy-three mothers whose red blood cells bore an Rh antigen (Rh D, Rh c, Rh E) that was absent on red blood cells of their newborns were identified and a new cytological method, the Kleihauerimm...

journal_title：Vox sanguinis

authors： Brossard Y,Pons JC,Jrad I,van Nifterik J,Gillot R,Saure C,Le Gaudion M,Richard A,Papiernik E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is a member of the coronavirus family. Coronavirus infections in humans are typically associated with respiratory illnesses; however, viral RNA has been isolated in...

journal_title：Vox sanguinis

authors： Keil SD,Ragan I,Yonemura S,Hartson L,Dart NK,Bowen R

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Miltenberger subtype III (Mi.III, GP.Mur) is one of the most important red cell phenotypes in the fields of transfusion in South-East Asia. GP.Mur is believed to evolve from homologous gene recombination events between glycophorin A (GYPA) and glycophorin B (GYPB). GYP.Mur differs from GYPB in...

journal_title：Vox sanguinis

authors： Hsu K,Yao CC,Lin YC,Chang CL,Lee TY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous data that showed maintenance of reticulocyte percentage in whole blood stored in CPDA-1 have led to the assumption that reticulocyte maturation becomes arrested during refrigerated storage. However, reticulocyte behaviour in red-blood-cell units stored in additive solutions has not ye...

journal_title：Vox sanguinis

authors： Urbina A,Palomino F

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Gene conversion events between GYPA and GYPB or GYPA and GYPE are facilitated by the close chromosomal proximity and high degree of sequence homology and can lead to the formation of GP hybrid genes. Discrepant results between blood group genotyping and haemagglutination in 22 random blood don...

journal_title：Vox sanguinis

authors： Polin H,Danzer M,Reiter A,Brisner M,Gaszner W,Weinberger J,Gabriel C

更新日期：2014-11-01 00:00:00

abstract：:An attempt was made to confirm a previously reported association between HLA type B16 and resistance to infection with live attenuated influenza A virus vaccine. No differences were found either in the ability of influenza virus to attach to fractionated white blood cells from HLB B16 subjects compared to cells from s...

journal_title：Vox sanguinis

authors： Mackenzie JS,Wetherall JD,Flower RL,Fimmel PJ,Dawkins RL

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:There exists only few data on in vitro and in vivo effects of gamma irradiation of leucoreduced red blood cells (RBCs). Reported studies reflect the effects of early irradiation and subsequent storage. The effects of irradiation on RBCs shortly before the end of their shelf-life have not been examined. STUD...

journal_title：Vox sanguinis

authors： Zimmermann R,Schoetz AM,Frisch A,Hauck B,Weiss D,Strobel J,Eckstein R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A patient transfused with two pooled platelet concentrates became breathless. Bilateral infiltrates were seen on chest X-ray. A diagnosis of transfusion-related acute lung injury (TRALI) was made. The patient received 100% oxygen and recovered after 5 days. MATERIALS AND METHODS:Antibody scre...

journal_title：Vox sanguinis

authors： Lucas G,Rogers S,Evans R,Hambley H,Win N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Blood transfusions can transmit parasitic infections, such as those caused by Plasmodium (malaria), Trypanosoma cruzi (Chagas' disease), and Babesia (babesiosis). A higher degree of blood transfusion safety would be reached if methods were available for inactivating such parasites. MATERIALS ...

journal_title：Vox sanguinis

authors： Grellier P,Santus R,Mouray E,Agmon V,Mazière JC,Rigomier D,Dagan A,Gatt S,Schrével J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:French Polynesia, where dengue virus (DENV) has been present for a long time, experienced two successive outbreaks of Zika (ZIKV) and chikungunya viruses (CHIKV) between 2013 and 2015. To avoid the transmission of these viruses by transfusion, nucleic acid testing (NAT) has been in place for D...

journal_title：Vox sanguinis

authors： Beau F,Mallet HP,Lastère S,Broult J,Laperche S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. METHODS:Donation (n = 180)...

journal_title：Vox sanguinis

authors： Feys HB,Coene J,Devloo R,Van Aelst B,Pottel H,Vandekerckhove P,Compernolle V

更新日期：2015-05-01 00:00:00

abstract：:Alpha1-Acid glycoprotein (orosomucoid) was prepared from a byproduct of the ethanol plasma fractionation by means of ion-exchange procedures. Immunoelectrophoresis suggested a high degree of purity; the purified protein contained 13.5% sialic acid and 17.8% hexose. The alpha1-acid glycoprotein was modified by removal ...

journal_title：Vox sanguinis

authors： van Rijk PP,Heinsius HL,van den Hamer CJ

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Glycocalicin (GC) is a proteolytic fragment of GpIb and can conveniently be measured in supernatants of platelet concentrates (PCs) by means of a sandwich ELISA. Because of the convenience of the assay and easy sample storage, we tested its suitability as a sensitive platelet activation parame...

journal_title：Vox sanguinis

authors： Kostelijk EH,Folman CC,Gouwerok CW,Kramer CM,Verhoeven AJ,de Korte D

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Bleeding is increasingly considered an important end point in clinical platelet transfusion studies. Accurate recording and adjudication into well-defined bleeding grades, however, remains a major challenge. METHODS:We developed a computer algorithm for automatic adjudication. The algorithm's results were...

journal_title：Vox sanguinis

authors： Middelburg RA,Ypma PF,van der Meer PF,van Wordragen-Vlaswinkel RJ,Eissen O,Kerkhoffs JL

更新日期：2013-08-01 00:00:00

abstract：:The Am and Bm phenotypes are characterized by weak expression of the A or B antigens, respectively, by red blood cells with a normal expression by the saliva of secretors. Deletion of the regulatory element in the first intron of the ABO gene and disruption of the GATA motif in the element were found to be responsible...

journal_title：Vox sanguinis

authors： Oda A,Isa K,Ogasawara K,Kameyama K,Okuda K,Hirashima M,Ishii H,Kimura K,Matsukura H,Hirayama F,Kawa K

更新日期：2015-05-01 00:00:00

abstract：:Isoagglutinins were investigated following ABO-incompatible bone marrow transplantation. In major incompatibility anti-A tends to require more time to disappear than anti-B. Correspondingly, A erythrocytes require more time to become demonstrable. There is no such difference in major plus minor incompatibility. In min...

journal_title：Vox sanguinis

authors： Wernet D,Mayer G

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Weak D phenotypes with very low antigen densities and DEL phenotype may not be detected in RhD typing routine and could be typed as D-negative, leading to D alloimmunization of D-negative recipients. The present study aimed to investigate the presence of RHD-positive genotypes in blood donors ...

journal_title：Vox sanguinis

authors： de Paula Vendrame TA,Prisco Arnoni C,Guilhem Muniz J,de Medeiros Person R,Pereira Cortez AJ,Roche Moreira Latini F,Castilho L

更新日期：2019-11-01 00:00:00

abstract：:IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infect...

journal_title：Vox sanguinis

authors： Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström T

更新日期：1986-01-01 00:00:00