The incidence and consequences of cytomegalovirus transmission via blood transfusion to low birth weight, premature infants in north east Scotland.

abstract：:Blood transfusion practices have evolved empirically, with few or no research data supporting them. In the past several decades, fuelled by fears of infection and reports of mistakes, patients have increasingly demanded their rights to choice, both in the components given to them as well as to refuse to receive these ...

journal_title：Vox sanguinis

authors： Sazama K

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hepcidin is the main hormone that regulates iron balance. Its lowering favours digestive iron absorption in cases of iron deficiency or enhanced erythropoiesis. The careful dosage of this small peptide promises new diagnostic and therapeutic strategies. Its measurement is progressively being v...

journal_title：Vox sanguinis

authors： Waldvogel S,Rochat B,Peduzzi D,Vaucher P,Tissot JD,Favrat B

更新日期：2016-02-01 00:00:00

abstract：:Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal anaemia with a risk for fetal death and to severe forms of neonatal hyperbilirubinaemia with a risk for kernicterus. Most severe cases are caused by anti-D,...

journal_title：Vox sanguinis

authors： de Haas M,Thurik FF,Koelewijn JM,van der Schoot CE

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:HPA-1a antibodies account for 70-80% of cases of fetal-neonatal alloimmune thrombocytopenia (FNAIT) in Caucasians. However, numerous workshops have demonstrated variability in their detection. We recently showed that exposure of αIIbβ3 to ethylene diamine tetraacetic acid (EDTA) affected bindi...

journal_title：Vox sanguinis

authors： Allen DL,Metcalfe P,Kaplan C,Kekomaki R,de Haas M,Yusuf R,Ouwehand WH

更新日期：2013-08-01 00:00:00

abstract：:Direct immunofluorescent staining of 31 specimens of platelets obtained from 13 cases of idiopathic thrombocytopenic purpura (ITP) revealed positive staining on the surface of platelets for both immunoglobulins (Igs) and human B1C globulin in 9 specimens, for only Igs in 1 specimen and for human B1C alone in 5 specime...

journal_title：Vox sanguinis

authors： Boonpucknavig S,Vuttivirojana O,Srichaikul T

更新日期：1979-01-01 00:00:00

abstract：:Human IgG separated by Cohn fractionation showed variability in the content of aggregates, plasminogen and anticomplement activity. The plasminogen was removed or markedly reduced by affinity chromatography on Sepharose-lysine. Anticomplement activity was reduced by chromatography of Cohn fraction II on DEAE-cellulose...

journal_title：Vox sanguinis

authors： Habeeb AF,Francis RD

更新日期：1977-01-01 00:00:00

abstract：:Emerging data in animal models and humans suggest that pathogen-associated and damage-associated molecular patterns variably impact RBC alloantibody formation. In this study, we tested the hypothesis that vaccinations may enhance immune responses to transfused RBCs. The Pneumovax23 vaccine decreased the magnitude of a...

journal_title：Vox sanguinis

authors： Natarajan P,Santhanakrishnan M,Tormey CA,Hendrickson JE

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Our post-thaw cell recovery rates differed substantially in interlaboratory comparisons of identical samples, potentially due to different temperatures during cell staining. MATERIALS AND METHODS:Viable CD34(+) cells and leucocyte (WBC) subtypes were quantified by multiparameter single-platfo...

journal_title：Vox sanguinis

authors： Fritsch G,Frank N,Dmytrus J,Frech C,Pichler H,Witt V,Geyeregger R,Scharner D,Trbojevic D,Zipperer E,Printz D,Worel N

更新日期：2016-08-01 00:00:00

abstract：:A substantial body of animal data indicates that transmissible spongiform encephalopathies (TSEs) are transmitted through blood. These data have been augmented in the past year by reports that two recipients of red cells from donors with variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom have acquired this...

journal_title：Vox sanguinis

authors： Farrugia A,Ironside JW,Giangrande P

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Analysis of haemoglobin (Hb) dilution after bleeding is a simple, inexpensive and non-invasive method to estimate blood loss. Blood volume is estimated, taking sex, weight and height into account. The Hb concentration before and after blood loss is analysed and, from the difference, the blood ...

journal_title：Vox sanguinis

authors： Meunier A,Petersson A,Good L,Berlin G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

journal_title：Vox sanguinis

authors： Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Factor VIII (FVIII) levels are used as a quality marker of fresh-frozen plasma (FFP); however, other clotting factors are not routinely measured. METHODS:We assessed additional haemostatic parameters and the dynamics of coagulation using Thrombelastography (TEG) and a thrombin generation test (TGT). FFP was...

journal_title：Vox sanguinis

authors： Lawrie AS,Cardigan RA,Williamson LM,Machin SJ,Mackie IJ

更新日期：2008-05-01 00:00:00

abstract：:Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Op...

journal_title：Vox sanguinis

authors： Lancé MD,Marcus MA,van Oerle R,Theunissen HM,Henskens YM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:IgG subclasses of anti-D seem to play some role in hemolytic disease of the newborn, but there has been disagreement as to its exact nature. The aim of our study was to evaluate a new technique for IgG subclassing of anti-D and to compare it to an established test. MATERIALS AND METHODS:In 31...

journal_title：Vox sanguinis

authors： Palfi M,Hildén JO

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The study was designed to evaluate whether volume replacement following blood donation can prevent arterial hypotension in autologous blood donors with cardiovascular disease. MATERIALS AND METHODS:One hundred nineteen autologous blood donors with known cardiovascular disease were randomly al...

journal_title：Vox sanguinis

authors： Kasper SM,Dahlmann H,Mellinghoff H,Ellering J,Baumann M,Buzello W

更新日期：1998-01-01 00:00:00

abstract：:Although we still do not know enough about the influence of anaemia and transfusion on outcomes for the surgical patient, it is possible to develop a general consensus about many aspects of management. A quality programme to improve consistency of practice in these consensus areas is feasible. (Table 6) This should be...

journal_title：Vox sanguinis

authors： McClelland B

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：:Routine screening of blood donations for anti-HIV commenced in the UK during October 1985 and by the end of February 1987 approximately 3.7 million donations had been tested. Seventy-two were confirmed anti-HIV positive, i.e. 0.002%. Of the anti-HIV-positive donors interviewed to date, the majority are young homosexua...

journal_title：Vox sanguinis

authors： Gunson HH,Rawlinson VI

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In previous studies, we found that platelet microparticles (PMPs) bind to cord blood (CB) CD34+ cells and transfer adhesion molecules to them, which enhances their engraftment. Before applying this phenomenon in actual transplants, we investigated the effect of PMPs on cryopreserved CD34+ cell...

journal_title：Vox sanguinis

authors： Liu B,Chen JS,Cao M,Gu SL,Liao C,Li DZ,Zhong HZ

更新日期：2004-08-01 00:00:00

abstract：:Sera from 2,829 participants in a population health survey were tested for the presence of a heterophilic antibody, detectable by immunofluorescence. The antibody was found in 9.8% of the sera from women and in 12.4% of the sera from men. The age-specific prevalence of the antibody was relatively constant in women but...

journal_title：Vox sanguinis

authors： Hawkins BR,Saueracker GC,Dawkins RL,Davey MG,O'Connor KJ

更新日期：1980-12-01 00:00:00

abstract：:An antibody to a high frequency antigen, made in a WES+ Black antenatal patient (Wash.), failed to react with the red cells of a presumed WES+ homozygote and is, therefore, probably antithetical to anti-WES. Like anti-WES, it reacted with papain, ficin, trypsin or neuraminidase treated cells but not with alpha-chymotr...

journal_title：Vox sanguinis

authors： Daniels GL,Green CA,Darr FW,Anderson H,Sistonen P

更新日期：1987-01-01 00:00:00

abstract：:BS II lectin, a second hemagglutinin isolated from Bandeiraea simplicifolia seeds, agglutinated the red cells from 11 patients manifesting the 'acquired B' antigen phenomenon. The results of serological studies indicate that this lectin has specificity for the type III polyagglutinable receptors rather than for the 'B...

journal_title：Vox sanguinis

authors： Judd WJ,Beck ML,Hicklin BL,Iyer PN,Goldstein IJ

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In accordance with Food and Drug Administration (FDA) regulations, platelets can be stored in the liquid state at 22 degrees C for only 5 days. Platelets frozen with 6% dimethylsulphoxide (DMSO) can be stored at -80 degrees C for 2 years, and platelets frozen with 5% DMSO can be stored at -150...

journal_title：Vox sanguinis

authors： Valeri CR,MacGregor H,Barnard MR,Summaria L,Michelson AD,Ragno G

更新日期：2005-02-01 00:00:00

abstract：:The Am and Bm phenotypes are characterized by weak expression of the A or B antigens, respectively, by red blood cells with a normal expression by the saliva of secretors. Deletion of the regulatory element in the first intron of the ABO gene and disruption of the GATA motif in the element were found to be responsible...

journal_title：Vox sanguinis

authors： Oda A,Isa K,Ogasawara K,Kameyama K,Okuda K,Hirashima M,Ishii H,Kimura K,Matsukura H,Hirayama F,Kawa K

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Routine serologic D typing does not distinguish between weak D subtypes and partial D phenotypes. The goal of this study was to validate the performance of the ID RHD XT genotyping assay. MATERIAL AND METHODS:Previously serotyped samples for D antigen (n = 1000; 16% weak D serotyped donors) w...

journal_title：Vox sanguinis

authors： Molano A,Apraiz I,España P,Azkarate M,Vesga MÁ,Rubia M,Piedrabuena M,Puente F,Veldhuisen B,van der Schoot E,Tejedor D,López M

更新日期：2018-10-01 00:00:00

abstract：:We tested serum samples from 11 HIV-seropositive and 32 HIV-seronegative Italian patients with hemophilia A or B for the presence of lymphocytotoxic antibodies (LCTAs). No patients had the acquired immune deficiency syndrome and all had received over many years heat-untreated commercial clotting factors. LCTAs directe...

journal_title：Vox sanguinis

authors： Conte R,Giovanardi L,Tazzari PL,De Rosa V,Rodorigo G,Re MC

更新日期：1988-01-01 00:00:00

abstract：:We simulated the use of massive volumes of crystalloid fluids as a treatment of acute plasma loss in a standardized experimental model and studied the factors determining the retention or excretion of the resulting acute hypoproteinemic fluid overload, its distribution within the body, and its treatment with concentra...

journal_title：Vox sanguinis

authors： Pappova E,Bachmeier W,Crevoisier JL,Kollar J,Kollar M,Tobler P,Zahler HW,Zaugg D,Lundsgaard-Hansen P

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previous studies with p38MAPK inhibitors at room temperature demonstrated that they improve a large number of platelet storage parameters, but cannot substantially inhibit p38MAPK activation nor protect against widespread decrements in platelet quality parameters during 4 °C storage. In this s...

journal_title：Vox sanguinis

authors： Wagner SJ,Skripchenko A,Seetharaman S,Kurtz J

更新日期：2015-04-01 00:00:00

abstract：:Prolonged storage of red blood cells (RBCs) at 4 degrees C results in decreased intracellular ATP levels with diminished posttransfusion survival. Meryman described a preservative medium, exceptional in its capacity to increase these intracellular levels during the first weeks of storage and later in maintaining adequ...

journal_title：Vox sanguinis

authors： Mazor D,Dvilansky A,Meyerstein N

更新日期：1994-01-01 00:00:00

abstract：:Immunoblotting with human anti-Sc1 and anti-Sc2 locates the Sc1 and Sc2 antigens to an erythrocyte membrane glycoprotein of apparent Mr 60,000. The antigens are destroyed by pronase, and require intact disulphide bonds for expression. A proportion of the molecules carrying the Sc1 and Sc2 antigens are associated with ...

journal_title：Vox sanguinis

authors： Spring FA,Herron R,Rowe G

更新日期：1990-01-01 00:00:00