An erythrocyte glycoprotein of apparent Mr 60,000 expresses the Sc1 and Sc2 antigens.

Abstract:

:Immunoblotting with human anti-Sc1 and anti-Sc2 locates the Sc1 and Sc2 antigens to an erythrocyte membrane glycoprotein of apparent Mr 60,000. The antigens are destroyed by pronase, and require intact disulphide bonds for expression. A proportion of the molecules carrying the Sc1 and Sc2 antigens are associated with red cell cytoskeleton preparations. Treatment of intact cells with an Endo F preparation resulted in the loss of the Sc2 antigen but not the Sc1 antigen, suggesting that the Sc2 antigen is dependent on the presence of one or more complex N-glycans for its expression.

journal_name

Vox Sang

journal_title

Vox sanguinis

authors

Spring FA,Herron R,Rowe G

doi

10.1111/j.1423-0410.1990.tb02074.x

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

122-5

issue

2

eissn

0042-9007

issn

1423-0410

journal_volume

58

pub_type

杂志文章
  • Prospective study of posttransfusion hepatitis in cardiac surgery patients receiving only blood or also blood products.

    abstract::The incidence, etiology and risk factors of posttransfusion (PT) hepatitis were evaluated in a prospective study of 297 consecutive open-heart surgery patients. PT hepatitis occurred in 63 (21.2%) patients with a significantly higher hepatitis attack rate in 51 recipients of commercial clotting factor concentrates (56...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb04099.x

    authors: Tremolada F,Chiappetta F,Noventa F,Valfrè C,Ongaro G,Realdi G

    更新日期:1983-01-01 00:00:00

  • The HLA system: an update and relevance to patient-donor matching strategies in clinical transplantation.

    abstract::In recent years the development of recombinant DNA and sequencing techniques has led to a greatly increased understanding of the genetic complexity, structure and function of the human major histocompatibility complex. This system may be subdivided into the "classical' HLA (human leukocyte antigen) class I and II tran...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1046/j.1423-0410.1996.7110006.x

    authors: Howell WM,Navarrete C

    更新日期:1996-01-01 00:00:00

  • Re-evaluating the residual risk of transfusion-transmitted Ross River virus infection.

    abstract:BACKGROUND AND OBJECTIVES:Ross River virus (RRV) is an enveloped, RNA alphavirus in the same antigenic group as chikungunya virus. Australia records an annual average of 5000 laboratory-confirmed RRV infections. While RRV is currently geographically restricted to the Western Pacific, the capacity of arboviruses for rap...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12372

    authors: Seed CR,Hoad VC,Faddy HM,Kiely P,Keller AJ,Pink J

    更新日期:2016-05-01 00:00:00

  • Direct comparison of three residual risk models for hepatitis B virus window period infections using updated input parameters.

    abstract:BACKGROUND AND OBJECTIVES:Comparison of two models for estimating residual transfusion transmission risk by NAT screened window period (WP) donations in South African repeat donors gave identical results for HIV but not for HBV. In order to understand discrepant HBV modelling outcomes, the values of input parameters in...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/vox.12889

    authors: Lelie N,Vermeulen M,van Drimmelen H,Coleman C,Bruhn R,Reddy R,Busch M,Kleinman S

    更新日期:2020-04-01 00:00:00

  • A study of blood transfusion services at a district hospital in Malawi.

    abstract:BACKGROUND AND OBJECTIVES:Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use of and possibilities for blood transfusion services. The aims of this study are to explore the use of blood transfusion services at a hospital in sub-Saharan Africa and to asse...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2012.01628.x

    authors: Bugge HF,Karlsen NC,Oydna E,Rake MM,Wexels N,Bendabenda J,Roald B,Heier HE,Chisuwo L,Jourdan PM

    更新日期:2013-01-01 00:00:00

  • A new intact immunoglobulin for intravenous use stabilized by chemically modified gelatin derivatives.

    abstract::The stabilization of human immunoglobulin (IgG) by chemically modified gelatins (Haemaccel and Gelofusine) was investigated. The gelatins prevented IgG from aggregation induced by exposure to interfaces and lyophilization. The stabilization effects of the gelatins were significantly larger than those of amino acids or...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1986.tb00219.x

    authors: Tomono T,Ikeda K,Suzuki T

    更新日期:1986-01-01 00:00:00

  • A simple protocol for the screening and preliminary identification of antibodies to human IgA using unpurified proteins in the passive haemagglutination test.

    abstract::Experiments have shown that suitably diluted, unpurified IgA paraprotein sera can be substituted for chemically purified IgA proteins in the passive haemagglutination test for the detection of anti-IgA antibodies. The substitution of unpurified IgA paraprotein was made possible by the enhanced serological activity obt...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1990.tb02110.x

    authors: Hunt A,Reed M

    更新日期:1990-01-01 00:00:00

  • An improved method to study complement receptor-mediated function of the fixed macrophage system in vivo.

    abstract::A method to coat unsensitized erythrocytes with fragments of C3 and C4 using autologous serum, in order to study complement receptor-dependent function of the fixed macrophage system, is presented. After incubation with serum under optimal conditions, at least 90% of the cells had C3b/iC3b deposited on the surface, wi...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1991.tb00926.x

    authors: Nilsson Ekdahl K,Lööf L,Nilsson UR,Nilsson B

    更新日期:1991-01-01 00:00:00

  • Transfusion risk associated with recent arbovirus outbreaks in French Polynesia.

    abstract:BACKGROUND AND OBJECTIVES:French Polynesia, where dengue virus (DENV) has been present for a long time, experienced two successive outbreaks of Zika (ZIKV) and chikungunya viruses (CHIKV) between 2013 and 2015. To avoid the transmission of these viruses by transfusion, nucleic acid testing (NAT) has been in place for D...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12855

    authors: Beau F,Mallet HP,Lastère S,Broult J,Laperche S

    更新日期:2020-02-01 00:00:00

  • Use of monoclonal anti-C3 antibodies to characterise the fragments of C3 that are found on erythrocytes.

    abstract::Using monoclonal antibodies to C3 it has been shown that the red blood cells of patients with cold haemagglutinin disease carry on their cells C3d,g (alpha-2D-globulin) rather than C3d. C3d,g seems to be the final product of in vivo C3 activation in fluid phase and on red cells. The cleavage of C3dg to C3d and C3g doe...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1983.tb01928.x

    authors: Lachmann PJ,Voak D,Oldroyd RG,Downie DM,Bevan PC

    更新日期:1983-01-01 00:00:00

  • Molecular bases of the ABO blood groups of Indians from the Brazilian Amazon region.

    abstract::Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 Amazon...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1994.tb01255.x

    authors: Franco RF,Simões BP,Guerreiro JF,Santos SE,Zago MA

    更新日期:1994-01-01 00:00:00

  • Thrombocytopenia at birth in neonates with red cell alloimmune haemolytic disease.

    abstract:OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1423-0410.2011.01539.x

    authors: Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

    更新日期:2012-04-01 00:00:00

  • Model for the Rh blood group system based on discontinuous gene structure.

    abstract::A model of the Rh blood group system is proposed which is based on discontinuous gene structure. The R29 control subregion consists of a single exon flanked by introns. Following the R29 subregion, the R1 subregion exists as seven exon structures which alternate with introns. The expression of each exon is controlled ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1981.tb01022.x

    authors: Giorno R

    更新日期:1981-01-01 00:00:00

  • The low prevalence Rh antigen Be(a) (Rh36) is associated with RHCE*ce 662C>G in exon 5, which is predicted to encode Rhce 221Arg.

    abstract:BACKGROUND AND OBJECTIVES:The low prevalence antigen, Be(a), is produced by a complex that also produces weak c, e and f (ce). We report here the molecular basis associated with Be(a) antigen expression. MATERIALS AND METHODS:Peripheral blood samples from four Be(a+) probands were tested. Haemagglutination, gDNA extra...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2009.01277.x

    authors: Hue-Roye K,O'Shea K,Gillett R,Wadsworth LD,Hume H,Barnes J,Kinney J,Hodgins K,Fuchisawa A,Lomas-Francis C,Reid M

    更新日期:2010-04-01 00:00:00

  • Relevance of flow cytometric enumeration of post-thaw leucocytes: influence of temperature during cell staining on viable cell recovery.

    abstract:BACKGROUND AND OBJECTIVES:Our post-thaw cell recovery rates differed substantially in interlaboratory comparisons of identical samples, potentially due to different temperatures during cell staining. MATERIALS AND METHODS:Viable CD34(+) cells and leucocyte (WBC) subtypes were quantified by multiparameter single-platfo...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12398

    authors: Fritsch G,Frank N,Dmytrus J,Frech C,Pichler H,Witt V,Geyeregger R,Scharner D,Trbojevic D,Zipperer E,Printz D,Worel N

    更新日期:2016-08-01 00:00:00

  • Editorial: Red cell ageing and death.

    abstract::To obtain red cell populations of increasing mean age erythropoiesis was arrested through continuous actinomycin treatment or maintained transfusion polycythemia in mice and rats respectively. The parameters studied included cell indices, enzyme activities and rheological characteristics. Further, the life-span of age...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1976.tb02809.x

    authors: Ganzoni AM,Barras JP,Marti HR

    更新日期:1976-01-01 00:00:00

  • Simultaneous occurrence of anti-F1 and anti-I cold agglutinins in a patient's serum.

    abstract::The second example of anti-F1 cold agglutinins recognizing a developmentally regulated antigen like I is described. The antibody occurred transiently and simultaneously together with an anti-I cold agglutinin. Although anti-F1 and anti-I specificities are entirely different, the data on the biochemistry of F1 and I an...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1984.tb01573.x

    authors: Roelcke D,Weber MT

    更新日期:1984-01-01 00:00:00

  • Plasma temperature during methylene blue/light treatment influences virus inactivation capacity and product quality.

    abstract:BACKGROUND:Photodynamic treatment using methylene blue (MB) and visible light is in routine use for pathogen inactivation of human plasma in different countries. Ambient and product temperature conditions for human plasma during production may vary between production sites. The influence of different temperature condit...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12643

    authors: Gravemann U,Handke W,Sumian C,Alvarez I,Reichenberg S,Müller TH,Seltsam A

    更新日期:2018-05-01 00:00:00

  • The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis.

    abstract::With regard to hemostasis and thrombosis, collagens are among the most important physiologic components of the extracellular matrix in their role as platelet activators. Differences in the rate of platelet activation markedly influence normal hemostasis and the pathological outcome of thrombosis. Thus, collagen recept...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.2002.tb05274.x

    authors: Kunicki TJ,Nugent DJ

    更新日期:2002-08-01 00:00:00

  • A new liquid, intravenous immunoglobulin product (IGIV 10%) highly purified by a state-of-the-art process.

    abstract:BACKGROUND AND OBJECTIVES:The ultimate goal was to generate an industrial-scale process suitable to produce a high-yield, safe and stable immunoglobulin G (IgG) preparation for intravenous administration, which is ready to use for customer convenience. This new liquid 10% IgG preparation (IGIV 10%) was compared to Gamm...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2006.00846.x

    authors: Teschner W,Butterweck HA,Auer W,Muchitsch EM,Weber A,Liu SL,Wah PS,Schwarz HP

    更新日期:2007-01-01 00:00:00

  • Serratia marcescens strains implicated in adverse transfusion reactions form biofilms in platelet concentrates and demonstrate reduced detection by automated culture.

    abstract:BACKGROUND AND OBJECTIVES:Serratia marcescens is a gram-negative bacterium that has been implicated in adverse transfusion reactions associated with contaminated platelet concentrates. The aim of this study was to investigate whether the ability of S. marcescens to form surface-attached aggregates (biofilms) could acco...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.2011.01550.x

    authors: Greco-Stewart VS,Brown EE,Parr C,Kalab M,Jacobs MR,Yomtovian RA,Ramírez-Arcos SM

    更新日期:2012-04-01 00:00:00

  • Unusual serological response to hepatitis E virus in plasma donors consistent with re-infection.

    abstract::Hepatitis E virus (HEV)-positive plasma donations, identified by a plasma mini-pool screening approach, were analysed using serological methods for the presence of anti-HEV IgM and IgG. Avidity testing was performed on the IgG-reactive donations. Anti-HEV IgG with high avidity was observed in two donors together with ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12294

    authors: Baylis SA,Crossan C,Corman VM,Blümel J,Scobie L,Dalton HR

    更新日期:2015-11-01 00:00:00

  • Plasmodium falciparum malaria and the immunogenetics of ABO, HLA, and CD36 (platelet glycoprotein IV).

    abstract::Plasmodium falciparum malaria has long been a killer of the young, and has selected for polymorphisms affecting not only erythrocytes, but the immunogenetics of three histocompatibility systems: ABO, human leukocyte antigen (HLA), and CD36. The ABO system is important because the original allele, encoding glycosylatio...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.2010.01429.x

    authors: Cserti-Gazdewich CM,Mayr WR,Dzik WH

    更新日期:2011-01-01 00:00:00

  • Estimation of the infectious viral load required for transfusion-transmitted human T-lymphotropic virus type 1 infection (TT-HTLV-1) and of the effectiveness of leukocyte reduction in preventing TT-HTLV-1.

    abstract:BACKGROUND AND OBJECTIVES:The risk of transfusion-transmitted human T-lymphotropic virus type 1 infection (TT-HTLV-1) after prestorage leucocyte reduction (LR) remains unknown, as the proviral load in the blood component that would cause TT-HTLV-1 is undetermined. On the basis of the distribution of HTLV-1 proviral loa...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/vox.12263

    authors: Sobata R,Matsumoto C,Uchida S,Suzuki Y,Satake M,Tadokoro K

    更新日期:2015-08-01 00:00:00

  • World Health Organization collaborative study to calibrate the 3rd International Standard for Hepatitis C virus RNA nucleic acid amplification technology (NAT)-based assays.

    abstract:BACKGROUND AND OBJECTIVES:A collaborative study was undertaken to evaluate a replacement World Health Organization International Standard for hepatitis C virus (HCV) RNA for nucleic acid amplification technology (NAT)-based assays. The candidate preparations were calibrated in International Units (IUs). MATERIALS AND ...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1423-0410.2010.01434.x

    authors: Baylis SA,Heath AB,Collaborative Study Group.

    更新日期:2011-05-01 00:00:00

  • Further characterization of some heterophile agglutinins reacting with alkali-labile carbohydrate chains of human erythrocyte glycoproteins.

    abstract::The nature of the receptor sites for several agglutinins is characterized by hemagglutination inhibition assays. The inhibitory activity of human erythrocytes glycoproteins, from which sialic acid, sialic acid and galactose or alkali-labile oligosaccharides have been removed, is compared to the inhibitory effect of co...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1975.tb02751.x

    authors: Dahr W,Uhlenbruck G,Bird GW

    更新日期:1975-01-01 00:00:00

  • Hemovigilance in the United States of America.

    abstract::Although hemovigilance is not a word used commonly in the United States, the concept of monitoring morbidity associated with blood transfusion is accepted widely. Currently, quality management focuses on error avoidance rather than error detection in both the "manufacturing" and "clinical" aspects of blood banking. "M...

    journal_title:Vox sanguinis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1423-0410.1998.tb05455.x

    authors: Menitove JE

    更新日期:1998-01-01 00:00:00

  • Efficacy of heat treatment of factor VIII concentrate.

    abstract::Two batches of heat-treated factor VIII concentrate were found to contain anti-HIV-positive plasma donations. The batches were dry-heat-treated at 68 degrees C for 2 and 24 h, respectively. No HIV seroconversions occurred in 13 susceptible haemophiliacs receiving a total of 540 bottles of these factor VIII preparation...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1988.tb03904.x

    authors: Cuthbert RJ,Ludlam CA,Brookes E,McClelland DB

    更新日期:1988-01-01 00:00:00

  • Serological characterization of murine monoclonal antibodies directed against acquired B red cells.

    abstract::Balb/c mice were immunized with acquired B red cells. Twelve clones specific for acquired B red cells were obtained from two fusions. A detailed investigation of three clones is reported here. These antibodies appear to be directed to the B-like epitope since they are inhibited by galactosamine and fail to react after...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1111/j.1423-0410.1990.tb05017.x

    authors: Janvier D,Veaux S,Reviron M,Guignier F,Benbunan M

    更新日期:1990-01-01 00:00:00

  • Cost-effectiveness of solvent/detergent-treated fresh-frozen plasma.

    abstract:BACKGROUND AND OBJECTIVES:Although transfusion-transmitted infections are rare, non-infectious complications occur relatively frequently. Solvent/detergent-treated fresh-frozen plasma (SD-FFP) has been shown to reduce the frequency of both types of complication, although previous economic evaluations failed to consider...

    journal_title:Vox sanguinis

    pub_type: 杂志文章

    doi:10.1046/j.1423-0410.2003.00329.x

    authors: Riedler GF,Haycox AR,Duggan AK,Dakin HA

    更新日期:2003-08-01 00:00:00