Abstract:
:A retrospective analysis was conducted on 20 D(-) liver transplant (LT) recipients transfused with D(+) RBCs perioperatively and screened for RBC antibodies between 2 and 6 months later. None developed anti-D detectable by the indirect antiglobulin test. Two patients produced weak anti-D that reacted only with papain-treated RBCs at 10 and 11 days without any sign of immune haemolysis. Antibodies became quickly undetectable. These data suggest an unusual pattern of alloimmunization in LT recipients with rapid, weak and transient antibody response and support the safety of transfusing D(+) RBCs in most of D(-) patients during LT surgery.
journal_name
Vox Sangjournal_title
Vox sanguinisauthors
Burin des Roziers N,Ibanez C,Samuel D,Francoz C,Idri S,François A,Mortelecque R,Bierling P,Pirenne Fdoi
10.1111/vox.12392subject
Has Abstractpub_date
2016-07-01 00:00:00pages
107-10issue
1eissn
0042-9007issn
1423-0410journal_volume
111pub_type
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