The incidence of fragility fractures in Italy.

abstract：BACKGROUND AND AIM:Several measurements were taken for frailty classification in geriatric population. "Frailty index" is based on "deficits in health," but it is still not available in Italian version. Thus, the aim of the present work was to validate a version of "frailty index" for the Italian geriatric community. ...

journal_title：Aging clinical and experimental research

authors： Abete P,Basile C,Bulli G,Curcio F,Liguori I,Della-Morte D,Gargiulo G,Langellotto A,Testa G,Galizia G,Bonaduce D,Cacciatore F

更新日期：2017-10-01 00:00:00

abstract：:MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series...

journal_title：Aging clinical and experimental research

authors： Cruz-Jentoft AJ,Daragjati J,Fratiglioni L,Maggi S,Mangoni AA,Mattace-Raso F,Paccalin M,Polidori MC,Topinkova E,Ferrucci L,Pilotto A,MPI_AGE Investigators.

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:The circadian rhythm of serum thyroid stimulating hormone (TSH) levels in patients with Alzheimer's disease was measured by means of a case-control study. METHODS:Serum samples from cases and controls were collected continuously for 2 days, and then once every 2 h (even number time-point during the first da...

journal_title：Aging clinical and experimental research

authors： Chen JM,Huang CQ,Ai M,Kuang L

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...

journal_title：Aging clinical and experimental research

authors： Bardach SH,Holmes SD,Jicha GA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Cognitive impairment is common among stroke survivors. However, there is controversy on the role of the stroke itself or the associated subcortical damage in post-stroke cognitive decline. AIM:To assess the independent contribution and the interaction of age, the stroke itself and diffuse subcortical damage...

journal_title：Aging clinical and experimental research

authors： Del Brutto OH,Mera RM,Zambrano M,Lama J

更新日期：2015-10-01 00:00:00

abstract：:Older adults in Latin America are at an increased risk of hospitalisation, ill health, catastrophic disability and death due to vaccine-preventable diseases such as influenza, herpes zoster, and pneumonia. The Latin American Adult Immunisation Advocacy Summit, held in Mexico City, gathered 40 experts in health, ageing...

journal_title：Aging clinical and experimental research

authors： Barratt J,Mishra V,Acton M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Aging has several effects on auditory processing with the most important effect known as speech perception impairment in noise. AIMS:The aim of the present study was to investigate the effects of aging on spatial hearing using quick speech in noise (QSIN) and binaural masking level difference (BMLD) tests a...

journal_title：Aging clinical and experimental research

authors： Adel Ghahraman M,Ashrafi M,Mohammadkhani G,Jalaie S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Gait disorders are common in the elderly populations, and their prevalence increases with age. Abnormal gait has been associated with greater risk for adverse outcomes in older adults, such as immobility and falls, which in turn lead to loss of functional independence and death. AIM:The purpose of this revi...

journal_title：Aging clinical and experimental research

authors： Aboutorabi A,Arazpour M,Bahramizadeh M,Hutchins SW,Fadayevatan R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Marital and parental role characteristics are important factors in both men and women's health. Most studies to date have either focused on disease specific outcomes or summary measures of self-reported health rather than using functional tests of performance. The goal of this study is to investigat...

journal_title：Aging clinical and experimental research

authors： Guralnik JM,Butterworth S,Patel K,Mishra G,Kuh D

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The platelet to lymphocyte ratio (PLR) is a novel biomarker to predict the prognosis of acute myocardial infarction (AMI) patients. AIM:The study aimed to evaluate the in-hospital outcomes of elderly patients with AMI and assessed the prognostic value of PLR on in-hospital adverse events. METHODS:A total o...

journal_title：Aging clinical and experimental research

authors： Li L,Ma Y,Geng XB,Tan Z,Wang JH,Cui C,Wang HL,Shang XM

更新日期：2020-04-16 00:00:00

abstract：:Age-related macular disease (AMD) is the leading cause of legal blindness among the elderly in Western nations. The magnitude of the problem will undoubtedly grow, as age is a significant risk factor and the number of people aged 65 and over is projected to increase. The most frequent cause of severe visual loss assoc...

journal_title：Aging clinical and experimental research

authors： Bellmann C,Kabanarou SA,Sahel JA,Rubin GS,Fitzke FW

更新日期：2005-12-01 00:00:00

abstract：:Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to m...

journal_title：Aging clinical and experimental research

authors： Piarulli G,Rossi A,Zatti G

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Nitric oxide (NO) may play a critical role in facilitating the delivery of blood to active skeletal muscle, ultimately impacting functional health in older adults. Plasma nitrite is a useful marker of vascular NO bioavailability. The aim of the current investigation was to examine the effect of a wi...

journal_title：Aging clinical and experimental research

authors： Dobrosielski DA,Presley T,Perlegas A,Marsh AP,Kim-Shapiro D,Rejeski WJ

更新日期：2010-10-01 00:00:00

abstract：AIM:We report 3 cases of spontaneous insufficiency fracture of long bones, to promote awareness of this phenomenon to medical personnel dealing with long-term bedridden patients. METHODS:Cases were analyzed in the light of a literature review. RESULTS:Our patients were all women, who were severely debilitated and had...

journal_title：Aging clinical and experimental research

authors： Manevich D,Brill S,Hershkovitz A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...

journal_title：Aging clinical and experimental research

authors： Wang P,Li Y,Zhuang H,Yu H,Cai S,Xu H,Chen Z,Lin J,Yao X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:While caloric restriction (CR) is associated with a prolonged lifespan in multiple species by regulating metabolism, a comprehensive profile of metabolism under CR conditions remains largely unclear. Therefore, in this study we aimed to characterize the metabolomic profiling associated with CR using...

journal_title：Aging clinical and experimental research

authors： Zhang Y,Yan S,Gao X,Xiong X,Dai W,Liu X,Li L,Zhang W,Mei C

更新日期：2012-02-01 00:00:00

abstract：:Mood disorders are common and often under-recognised in older people whereby, together with the general ageing of the population, they are becoming a significant and growing public health problem worldwide. However, the need to address the problem of late life mood disorders in a real-world setting is met with a surpr...

journal_title：Aging clinical and experimental research

authors： Ghio L,Vaggi M,Amore M,Ferrannini L,Natta W

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:In spite of a rapidly ageing population, there is a lack of population-based data on mortality among nursing home residents in Southern Europe. AIMS:To assess mortality rates, their determinants, and causes of death in newly admitted nursing home residents in the Veneto region (northeastern Italy). METHODS...

journal_title：Aging clinical and experimental research

authors： Braggion M,Pellizzari M,Basso C,Girardi P,Zabeo V,Lamattina MR,Corti MC,Fedeli U

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIMS:As life expectancy rises worldwide and the population grows older, psychopathology in older adults becomes a significant public health concern and intervention methods acquire renewed importance. The aim of the present study was to assess the efficacy of Life Review as an intervention strategy in wo...

journal_title：Aging clinical and experimental research

authors： Gonçalves DC,Albuquerque PB,Paul C

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Most elderly persons live in developing countries where current geriatric epidemiological data are scarce. We aimed to study major comorbidities, polypharmacy, functional and nutritional status in a Turkish community-dwelling female elderly clinic population. METHODS:Female geriatrics outpatient cl...

journal_title：Aging clinical and experimental research

authors： Bahat G,Tufan F,Bahat Z,Tufan A,Aydin Y,Akpinar TS,Nadir S,Erten N,Karan MA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Incisional hernia in aged patients represents a challenge even for experienced surgeons. Besides increased risk of complications due to comorbidities, mesh fixation and assuring a sufficient mesh overlap of the defect are the main issues in carrying out the repair. AIMS:In order to assure broader coverage o...

journal_title：Aging clinical and experimental research

authors： Romano G,Calò PG,Erdas E,Medas F,Gordini L,Podda F,Amato G

更新日期：2017-02-01 00:00:00

abstract：:We describe a family composed of six siblings, four of which affected by late-onset Alzheimer's disease (LOAD). We constructed the family pedigree, evaluated mutations usually associated with early-onset Alzheimer's disease (APP, PSEN1, PSEN2), and assessed polymorphisms in the apolipoprotein E (APOE) gene and in cyto...

journal_title：Aging clinical and experimental research

authors： Abbate C,Arosio B,Cantatore A,Viti N,Giunco F,Bagarolo R,Nicolini P,Gussago C,Ferri E,Casati M,Rossi PD,Casè A,Bergamaschini L,Vergani C,Mari D

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Higher age is associated with reduced physical capability in the general population. The role of age and gender for physical performance in older adults who exercises regularly is, however, not clear, and there is also a lack of recommendations for outcomes to address physical performance for this population...

journal_title：Aging clinical and experimental research

authors： Tangen GG,Robinson HS

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:For people with dementia, moving into a nursing home is usually considered at some point in time. Currently available information on predictors of institutionalization is often based on small sample sizes, not taking competing risks into account, and with inconclusive results for sex. AIMS:We aimed to carry...

journal_title：Aging clinical and experimental research

authors： Runte R

更新日期：2018-01-01 00:00:00

abstract：:Senescence of the brain seems to be related to increased levels of free oxygen radical (FOR). FOR may damage macromolecular compounds such as: proteins, lipids, and DNA. In the aging brain, increased FOR levels damage DNA, mitochondrial DNA (mtDNA), and nuclear DNA (nDNA). In DNA they damage single and double strands,...

journal_title：Aging clinical and experimental research

authors： Dorszewska J

更新日期：2013-04-01 00:00:00

abstract：:Parkinson's disease (PD) typically occurs in elderly people and some degree of cognitive impairment is usually present. Cognitive reserve (CR) theory was proposed to explain the discrepancy between the degree of brain pathologies and clinical manifestations. We administered a comprehensive neuropsychological battery t...

journal_title：Aging clinical and experimental research

authors： Ciccarelli N,Monaco MRL,Fusco D,Vetrano DL,Zuccalà G,Bernabei R,Brandi V,Pisciotta MS,Silveri MC

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Nursing home institutionalization tends to exacerbate loss of functioning. AIMS:Examine the feasibility and the effect of a psychomotor intervention-a multimodal exercise program promoting simultaneous cognitive and motor stimulation-on the executive (planning ability and selective attention) and physical f...

journal_title：Aging clinical and experimental research

authors： Pereira C,Rosado H,Cruz-Ferreira A,Marmeleira J

更新日期：2018-05-01 00:00:00

abstract：:Finding a biomarker of long length-of-stay (LOS) would provide a simple solution to target frail older inpatients at such risk. The aim of this study was to determine whether serum 25-hydroxyvitamin D (25OHD) deficiency, defined as serum concentration <25 nmol/L, was associated with long LOS among inpatients admitted ...

journal_title：Aging clinical and experimental research

authors： Beauchet O,Launay CP,Maunoury F,de Decker L,Fantino B,Annweiler C

更新日期：2013-04-01 00:00:00

abstract：:Antioxidative/oxidative balance is one of the important factors for homeostasis. Antioxidative systems which protect from peroxidative damage are supposed to be under the influence of steroid hormones. The implications of this influence are age and gender as well as tissue dependent alterations in antioxidative enzyme...

journal_title：Aging clinical and experimental research

authors： Giergiel M,Lopucki M,Stachowicz N,Kankofer M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Age-related structural alterations in motor units and consequential functional manifestations are asserted to underlie the decline in the ability to finely grade, or control, muscular force in upper extremity musculature of older adults. Functional activities requiring appropriately graded muscular ...

journal_title：Aging clinical and experimental research

authors： Bellew JW

更新日期：2002-02-01 00:00:00