Analysis of urinary metabolic profile in aging rats undergoing caloric restriction.

abstract：BACKGROUND:Falling is a significant concern for many elderly adults but identifying individuals at risk of falling is difficult, and it is not clear how elderly adults adapt to challenging walking. AIMS:The aim of the current study was to determine the effects of walking at non-preferred speeds on the coordination bet...

journal_title：Aging clinical and experimental research

authors： Craig JJ,Bruetsch AP,Huisinga JM

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Cutbacks in human resources are putting home care personnel under increasing pressure in their work. Home health care personnel need to know how they can prevent undesirable conditions and support older people towards successful aging. The aim of this ten-year follow-up study was to identify factors...

journal_title：Aging clinical and experimental research

authors： Arve S,Savikko N,Lavonius S,Lehtonen A,Isoaho H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Cognitive impairment is common among stroke survivors. However, there is controversy on the role of the stroke itself or the associated subcortical damage in post-stroke cognitive decline. AIM:To assess the independent contribution and the interaction of age, the stroke itself and diffuse subcortical damage...

journal_title：Aging clinical and experimental research

authors： Del Brutto OH,Mera RM,Zambrano M,Lama J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication after orthopedic surgery, which is not conducive to the prognosis of the elderly. AIMS:We performed this study to investigate the effects of oxycodone applied for patient-controlled intravenous analgesia (PCIA) on postoperative cognitive fu...

journal_title：Aging clinical and experimental research

authors： Gan J,Tu Q,Miao S,Lei T,Cui X,Yan J,Zhang J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Acetylcholinesterase inhibitor (AChEis) therapy in Alzheimer Disease (AD) has been shown to provide cognitive benefits and to slow progression of the disease. AChEis have also been demonstrated to improve behavioral symptoms, although there seem to be subtle differences in the magnitude of response....

journal_title：Aging clinical and experimental research

authors： Rozzini L,Vicini Chilovi B,Bertoletti E,Trabucchi M,Padovani A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:In spite of a rapidly ageing population, there is a lack of population-based data on mortality among nursing home residents in Southern Europe. AIMS:To assess mortality rates, their determinants, and causes of death in newly admitted nursing home residents in the Veneto region (northeastern Italy). METHODS...

journal_title：Aging clinical and experimental research

authors： Braggion M,Pellizzari M,Basso C,Girardi P,Zabeo V,Lamattina MR,Corti MC,Fedeli U

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Carotid sinus hypersensitivity (CSH) is a common cause of fainting and falls in the older adult population and is diagnosed by carotid sinus massage (CSM). Previous work has suggested that age-related stiffening of blood vessels reduces afferent input from the carotid sinus leading to central upregu...

journal_title：Aging clinical and experimental research

authors： Madden KM,Lockhart C,Khan K

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...

journal_title：Aging clinical and experimental research

authors： Rantanen T,Hassandra M,Pynnönen K,Siltanen S,Kokko K,Karavirta L,Kauppinen M,Sipilä S,Saajanaho M,Portegijs E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Proximal femoral fracture is often associated with long-term residual disability. Quadriceps weakness may be a factor in poor outcome. This study aimed to determine whether training of the quadriceps using electrical stimulation (ES) increases leg extensor power and decreases disability in elderly s...

journal_title：Aging clinical and experimental research

authors： Braid V,Barber M,Mitchell SL,Martin BJ,Granat M,Stott DJ

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...

journal_title：Aging clinical and experimental research

authors： Kutsuna T,Hiyama Y,Kusaka S,Kusumoto Y,Tsuchiya J,Umeda M,Takahashi T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIMS:In Italy there is a paucity of empirical data on practices concerning end-of-life decisions (ELDs) in geriatrics. We aimed to investigate the frequency and characteristics of ELDs made by Italian physicians and nurses in the geriatric setting. METHODS:In 2009, an anonymous questionnaire was sent to...

journal_title：Aging clinical and experimental research

authors： Giantin V,Siviero P,Simonato M,Iasevoli M,Pengo V,Andrigo M,Storti M,Valentini E,Pegoraro R,Maggi S,Crepaldi G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：:We present a 61-year-old man with marked peripheral blood eosinophilia, feature of hypereosinophilic syndrome, that later evolved into acute lymphocytic leukemia (ALL-L2). Initially the patient suffered from significant complications related to eosinophilic toxicity, including large urticarial hyperpigmented plaques, ...

journal_title：Aging clinical and experimental research

authors： Song G,Liu H,Sun F,Gu L,Wang S

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and significance of the clinical application of ultrasound score in assessing the clinical severity of acute cholecystitis in the elderly. METHODS:Pre-surgery ultrasonography was performed on 72 elderly patients with acute cholecystitis who were scheduled for cholecystectomy to...

journal_title：Aging clinical and experimental research

authors： Zhang L,Han Q,Zhang H,Li D,Yao K

更新日期：2015-02-01 00:00:00

abstract：:The aim of the study was to look firstly at the changes that occurred in depressive symptomatology over a 5-year period among originally 75-year-old residents in three Nordic localities: Glostrup in Denmark, Göteborg in Sweden and Jyväskylä in Finland, and secondly, at some selected variables if they predicted depress...

journal_title：Aging clinical and experimental research

authors： Heikkinen RL,Berg S,Avlund K,Tömäkangas T

更新日期：2002-06-01 00:00:00

abstract：:Dysfunctional T-cell immunity contributes to susceptibility to infectious disease in the elderly. A characteristic feature of this "immunosenescence" is the predominance of clonal expansions of CD8 cells and decreased diversity of the T-cell antigen receptor repertoire. Lifelong chronic antigenic stress commonly cause...

journal_title：Aging clinical and experimental research

authors： Pawelec G,Gouttefangeas C

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND AIMS:To investigate mortality, determinants of mortality, and time until death among elderly subjects receiving public long-term care. METHODS:This study comprises 626 respondents (age: 65-98 years). Data were collected for two cohorts (2001 and 2002). Cox regression analysis was used to identify determ...

journal_title：Aging clinical and experimental research

authors： Jakobsson U,Hallberg IR

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate the effect of interdisciplinary outpatient geriatrics on the use, cost, and quality of health services in a fee-for-service (FFS) environment of two networks of primary care clinics operated by a not-for-profit provider organization in Dallas County, Texas. METHODS:The Senior Health Net...

journal_title：Aging clinical and experimental research

authors： Famadas JC,Frick KD,Haydar ZR,Nicewander D,Ballard D,Boult C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Aging, cancer and its treatment all contribute to increase the risk of deconditioning and sedentary behaviors. Mixed exercise is recognized to counteract the effects of aging and deconditioning as well as improving physical capacity during cancer treatment in adults. AIMS:To determine the impact of a mixed ...

journal_title：Aging clinical and experimental research

authors： Maréchal R,Fontvieille A,Parent-Roberge H,Fülöp T,Riesco E,Pavic M,Dionne IJ

更新日期：2019-11-01 00:00:00

abstract：:Excess of bone remodeling is still the major pathogenic factor in involutional osteoporosis. This phenomenon is linked to an imbalance between neoformation (by osteoblasts) and resorption (by osteoclasts). Recently, research in drug development is focused on new and more "physiological" approach to balance bone remode...

journal_title：Aging clinical and experimental research

authors： Iolascon G,Resmini G,Tarantino U

更新日期：2013-10-01 00:00:00

abstract：:The incidence of acetabular fractures in the elderly is recently becoming common. Acetabular fractures in this age range are more demanding, regarding fracture patterns, poor bone quality, patient status and potential comorbidities. Therefore it is necessary to determine the ideal treatment that should allow patients ...

journal_title：Aging clinical and experimental research

authors： D'Imporzano M,Liuni FM,Tarantino U

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Incisional hernia in aged patients represents a challenge even for experienced surgeons. Besides increased risk of complications due to comorbidities, mesh fixation and assuring a sufficient mesh overlap of the defect are the main issues in carrying out the repair. AIMS:In order to assure broader coverage o...

journal_title：Aging clinical and experimental research

authors： Romano G,Calò PG,Erdas E,Medas F,Gordini L,Podda F,Amato G

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:Despite the use of the new generation P2Y12 inhibitors (Ticagrelor and Prasugrel) with aspirin is the recommended therapy in acute NSTE-ACS patients, their current use in clinical practice remains quite low and might be related, among several variables, with increased comorbidity burden. We aimed to assess...

journal_title：Aging clinical and experimental research

authors： Aboal J,Llaó I,García García C,Sans-Roselló J,Sambola A,Andrea R,Tomás C,Bonet G,Ariza-Solé A,Viñas D,Oliveras Vilà T,Montero S,Cantalapiedra J,Pujol-López M,Hernández I,Pérez-Rodriguez M,Loma-Osorio P,Sánchez-Salado JC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Older adults' ever-improving health and changing lifestyles necessitate the development of a scale that can better measure their competence at a higher level. We developed the Japan Science and Technology Agency Index of Competence (JST-IC) via item analysis and assessed its psychometric properties....

journal_title：Aging clinical and experimental research

authors： Iwasa H,Masui Y,Inagaki H,Yoshida Y,Shimada H,Otsuka R,Kikuchi K,Nonaka K,Yoshida H,Yoshida H,Suzuki T

更新日期：2018-04-01 00:00:00

abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...

journal_title：Aging clinical and experimental research

authors： Belmin J,Bourée P,Camus D,Guiso N,Jeandel C,Trivalle C,Veyssier P

更新日期：2009-06-01 00:00:00

abstract：:Finding a biomarker of long length-of-stay (LOS) would provide a simple solution to target frail older inpatients at such risk. The aim of this study was to determine whether serum 25-hydroxyvitamin D (25OHD) deficiency, defined as serum concentration <25 nmol/L, was associated with long LOS among inpatients admitted ...

journal_title：Aging clinical and experimental research

authors： Beauchet O,Launay CP,Maunoury F,de Decker L,Fantino B,Annweiler C

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Lumbar spinal stenosis (LSS), osteoarthritis (OA) of the knee, and osteoporosis are major locomotive diseases in the elderly population. The aim of this study was to examine the effectiveness of exercise in these three diseases. METHODS:We reviewed the relevant literature, i.e., systematic reviews ...

journal_title：Aging clinical and experimental research

authors： Iwamoto J,Sato Y,Takeda T,Matsumoto H

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND AIMS:One of the factors playing a role in both the aging process and the etiopathogenesis of primary hypertension is oxidative stress. The purpose of this work was to estimate the production of nitric oxide (NO), oxidase activity of ceruloplasmin (Cp) and level of malondialdehyde (MDA), the end-product o...

journal_title：Aging clinical and experimental research

authors： Kedziora-Kornatowska K,Kornatowski T,Bartosz G,Pawluk H,Czuczejko J,Kedziora J,Szadujkis-Szadurski L

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Frailty is a geriatric syndrome that predicts increased morbidity and mortality. In order to investigate specific immune system modulations that may contribute to frailty, eleven age- and sex-matched pairs of community-dwelling frail and non-frail older adults were identified. METHODS:Peripheral bl...

journal_title：Aging clinical and experimental research

authors： Leng SX,Yang H,Walston JD

更新日期：2004-06-01 00:00:00

abstract：:Older adults in Latin America are at an increased risk of hospitalisation, ill health, catastrophic disability and death due to vaccine-preventable diseases such as influenza, herpes zoster, and pneumonia. The Latin American Adult Immunisation Advocacy Summit, held in Mexico City, gathered 40 experts in health, ageing...

journal_title：Aging clinical and experimental research

authors： Barratt J,Mishra V,Acton M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA and there is no effective treatment to stop its progression. Current pharmacologic treatments such as analgesics and non-steroidal anti-inflammatory drugs may improve the pain and offer some r...

journal_title：Aging clinical and experimental research

authors： Messina OD,Vidal Wilman M,Vidal Neira LF

更新日期：2019-06-01 00:00:00