Arterial stiffness and the response to carotid sinus massage in older adults.

abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...

journal_title：Aging clinical and experimental research

authors： Wang P,Li Y,Zhuang H,Yu H,Cai S,Xu H,Chen Z,Lin J,Yao X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs. METHODS:This population-based study, with a cross-sectional design, analysed all geriatric c...

journal_title：Aging clinical and experimental research

authors： Kallin K,Gustafson Y,Sandman PO,Karlsson S

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Falls causing injuries among older people and the consequences of those injuries are of increasing concern to public health practitioners. The aims of this study were to determine the incidence, characteristics and risk factors of fall injuries among the community-dwelling elderly in Shihpai, Taiwan...

journal_title：Aging clinical and experimental research

authors： Chang NT,Yang NP,Chou P

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...

journal_title：Aging clinical and experimental research

authors： Kucukdagli P,Bahat G,Bay I,Kilic C,Oren MM,Turkmen BO,Karan MA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Acetylcholinesterase inhibitor (AChEis) therapy in Alzheimer Disease (AD) has been shown to provide cognitive benefits and to slow progression of the disease. AChEis have also been demonstrated to improve behavioral symptoms, although there seem to be subtle differences in the magnitude of response....

journal_title：Aging clinical and experimental research

authors： Rozzini L,Vicini Chilovi B,Bertoletti E,Trabucchi M,Padovani A

更新日期：2007-06-01 00:00:00

abstract：:Neuroinflammation and cholinergic dysfunction, leading to cognitive impairment, are hallmarks of aging and neurodegenerative disorders, including Alzheimer's disease (AD). Acetylcholinesterase inhibitors (AChEI), the symptomatic therapy in AD, attenuate and delay the cognitive deficit by enhancing cholinergic synapses...

journal_title：Aging clinical and experimental research

authors： Benfante R,Di Lascio S,Cardani S,Fornasari D

更新日期：2019-10-03 00:00:00

abstract：BACKGROUND AND AIMS:Functional brain imaging has shown that bilateral brain reorganization may occur after unilateral cerebral damage. The present study searched for evidence of bilateral motor control changes in gait in patients with chronic unilateral stroke. METHODS:Gait variables (temporal and spatial parameters, ...

journal_title：Aging clinical and experimental research

authors： Titianova EB,Peurala SH,Pitkänen K,Tarkka IM

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Multimorbidity in older adults needs to be assessed as it is a risk factor for disability, cognitive decline, and mortality. AIMS:A community-based longitudinal study was performed to determine the incidence and to identify possible predictors of multimorbidity among multiethnic older adults population in M...

journal_title：Aging clinical and experimental research

authors： Hussin NM,Shahar S,Din NC,Singh DKA,Chin AV,Razali R,Omar MA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Proximal femoral fracture is often associated with long-term residual disability. Quadriceps weakness may be a factor in poor outcome. This study aimed to determine whether training of the quadriceps using electrical stimulation (ES) increases leg extensor power and decreases disability in elderly s...

journal_title：Aging clinical and experimental research

authors： Braid V,Barber M,Mitchell SL,Martin BJ,Granat M,Stott DJ

更新日期：2008-02-01 00:00:00

abstract：:New onset epilepsy and seizures are common neurological disorders in aged people, second only to stroke and dementia. They are frequently related to other pathological conditions including stroke, trauma, tumors and neurological diseases whereas in about one-third of cases the origin is unknown. Besides the origin, th...

journal_title：Aging clinical and experimental research

authors： Losi G,Gomez-Gonzalo M,Zonta M,Chiavegato A,Carmignoto G

更新日期：2019-11-15 00:00:00

abstract：OBJECTIVE:Attitude of healthcare providers toward older people is very important in the aging world. Neurologists contact older adults very frequently. We aimed to investigate the attitudes of neurologists toward older adults. MEASUREMENTS:We recorded participants age; sex; duration of clinical practice in neurology; ...

journal_title：Aging clinical and experimental research

authors： Seferoğlu M,Yıldız D,Pekel NB,Güneş A,Yıldız A,Tufan F

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Nursing home residents constitute a frail, multi-diseased and heterogeneous group. As physical activity is essential for the preservation of function, personalized training and activities are of great importance. The main objective of this study was to describe the influence of an individually tailo...

journal_title：Aging clinical and experimental research

authors： Frändin K,Borell L,Grönstedt H,Bergland A,Helbostad JL,Puggaard L,Andresen M,Granbo R,Hellström K

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. METHODS:We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Regis...

journal_title：Aging clinical and experimental research

authors： Wändell P,Carlsson AC,Li X,Gasevic D,Sundquist J,Sundquist K

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Accumulation of aggregated α-synuclein from the enteric nervous system is believed to be involved in the pathogenesis of Parkinson's disease (PD). The appendix contains abundant α-synuclein and lacks a blood-tissue barrier, suggesting that appendectomy might reduce α-synuclein aggregation, and therefore the ...

journal_title：Aging clinical and experimental research

authors： Lu HT,Shen QY,Xie D,Zhao QZ,Xu YM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common disease in elderly, characterized by poor bone quality as a result of alterations affecting trabecular bone. However, recent studies have described also an important role of alterations of cortical bone in the physiopathology of osteoporosis. Although dual-energy X-ray absorptiometry...

journal_title：Aging clinical and experimental research

authors： Feola M,Rao C,Tempesta V,Gasbarra E,Tarantino U

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Diagnosis of dementia is often difficult in subjects with low educational level. Our aim was to evaluate the role of functional performance and the possibility of preferring scores of activities of daily living (ADL) and instrumental activities of daily living (IADL) in screening elderly people for ...

journal_title：Aging clinical and experimental research

authors： Iavarone A,Milan G,Vargas G,Lamenza F,De Falco C,Gallotta G,Postiglione A

更新日期：2007-04-01 00:00:00

abstract：:Alzheimer and Parkinson's diseases are neurodegenerative aging-related pathological conditions, mainly caused by the interplay of genetic and non-genetic factors and whose incidence rate is going to drastically increase given the growing life expectancy. To address these complex multifactorial traits, a systems biolog...

journal_title：Aging clinical and experimental research

authors： Gentile G,La Cognata V,Cavallaro S

更新日期：2020-02-06 00:00:00

abstract：OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...

journal_title：Aging clinical and experimental research

authors： Gálvez-Barrón C,Sanguino MJ,Narvaiza L,Cavestany F,Collado I,Macho O,Dapena MD,Rodríguez-Molinero A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Muscle strength may decline with age differentially in the upper and lower limbs. This information is difficult to capture through a single measure. The present study therefore aimed to characterize the relative changes in handgrip and lower limb muscle strength with aging by expressing them as a ra...

journal_title：Aging clinical and experimental research

authors： Samuel D,Wilson K,Martin HJ,Allen R,Sayer AA,Stokes M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression. AIM:In this paper, we determine if resveratr...

journal_title：Aging clinical and experimental research

authors： Tung BT,Rodriguez-Bies E,Thanh HN,Le-Thi-Thu H,Navas P,Sanchez VM,López-Lluch G

更新日期：2015-12-01 00:00:00

abstract：:The patient, a 79-year-old woman with a history of osteoporosis, presented with acute back pain without trauma, three years ago. Spinal X rays showed a vertebral compression fracture at T7, and DXA indicated a T-score of -2.65 BMD at the total hip. The patient started treatment with alendronate 70 mg once a week, plus...

journal_title：Aging clinical and experimental research

authors： Resmini G,Iolascon G

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Elderly subjects are characterized by a high prevalence of chronic obstructive pulmonary disease (COPD) and frailty. This study examined the predictive role of frailty on long-term mortality in elderly subjects with and without COPD. METHODS:The study assessed mortality after a 12-year follow-up in...

journal_title：Aging clinical and experimental research

authors： Galizia G,Cacciatore F,Testa G,Della-Morte D,Mazzella F,Langellotto A,Raucci C,Gargiulo G,Ferrara N,Rengo F,Abete P

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...

journal_title：Aging clinical and experimental research

authors： Osuka Y,Kim H,Watanabe Y,Taniguchi Y,Kojima N,Seino S,Kawai H,Sakurai R,Inagaki H,Awata S,Shinkai S

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND AND AIMS:Cutbacks in human resources are putting home care personnel under increasing pressure in their work. Home health care personnel need to know how they can prevent undesirable conditions and support older people towards successful aging. The aim of this ten-year follow-up study was to identify factors...

journal_title：Aging clinical and experimental research

authors： Arve S,Savikko N,Lavonius S,Lehtonen A,Isoaho H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The purpose of this study was to determine the relationship between whole body energy metabolism measured as oxygen consumption (VO2) and local muscle activity measured by positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG). METHODS:Ten community- dwelling older women (73-83 yrs) h...

journal_title：Aging clinical and experimental research

authors： Shimada H,Sturnieks D,Endo Y,Kimura Y,Suzuki T,Oda K,Ishii K,Ishiwata K

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The MDS inter- RAI Acute Care is a comprehensive geriatric assessment tool for hospitalized older persons. The aim was to examine its validity based on test content by use in daily clinical practice. METHODS:Clinical staff of multiple disciplines assessed 256 older persons (83.2±5.2 years; 60% fema...

journal_title：Aging clinical and experimental research

authors： Wellens NI,Deschodt M,Boonen S,Flamaing J,Gray L,Moons P,Milisen K

更新日期：2011-10-01 00:00:00

abstract：:Osteoporosis can significantly impact on the risk of developing a fracture. Thus, fragility fractures represent a challenge for health professionals and decision makers of the twenty-first century. The aim of this work is to review the literature concerning osteoporotic fractures in Italy in terms of incidence, rate o...

journal_title：Aging clinical and experimental research

authors： Ratti C,Vulcano E,La Barbera G,Canton G,Murena L,Cherubino P

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The number of older persons admitted to the Emergency Department (ED) is dramatically increasing due to their complex medical and social problems, which in turn lead to longer clinical evaluation times and increased use of resources compared to younger adults. However, scant data are available for I...

journal_title：Aging clinical and experimental research

authors： Salvi F,Mattioli A,Giannini E,Vita D,Morichi V,Fallani M,Dessì-Fulgheri P,Cherubini A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Adaptation to strength training in very old mobility-limited individuals is not fully characterized. Therefore, the aim of this study was to perform a thorough investigation of the adaptation to a lower body strength training regime in this population, with particular emphasis on the relationship between cha...

journal_title：Aging clinical and experimental research

authors： Aas SN,Seynnes O,Benestad HB,Raastad T

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emerge...

journal_title：Aging clinical and experimental research

authors： Costa G,Bersigotti L,Massa G,Lepre L,Fransvea P,Lucarini A,Mercantini P,Balducci G,Sganga G,Crucitti A,ERASO (Elderly Risk Assessment, Surgical Outcome) Collaborative Study Group.

更新日期：2020-11-18 00:00:00