79-year-old post-menopausal woman with humerus fracture during teriparatide treatment.


:The patient, a 79-year-old woman with a history of osteoporosis, presented with acute back pain without trauma, three years ago. Spinal X rays showed a vertebral compression fracture at T7, and DXA indicated a T-score of -2.65 BMD at the total hip. The patient started treatment with alendronate 70 mg once a week, plus calcium and vitamin D supplementation. After two years, she presented new acute back pain, and spinal X-rays revealed new vertebral compression fractures at T8 and T11. In September 2004, she stopped alendronate therapy and began teriparatide 20 microg subcutaneously each day for 18 months, associated with a dose of 1200 mg/day of calcium and 880 IU/day of vitamin D. In July 2005, she fell and sustained a fracture of the left proximal humerus. She was treated with conservative therapy and continued teriparatide therapy. After 25 days of conservative management, left shoulder X-ray showed quick formation of fracture healing. In conclusion, although teriparatide is indicated for the treatment of severe osteoporosis and not to enhance fracture healing, there are many experimental data which indicate that it may be beneficial also in enhancing fracture healing.


Aging Clin Exp Res


Resmini G,Iolascon G


Has Abstract


2007-08-01 00:00:00




4 Suppl








  • Association between vitamin D deficiency and long hospital stay in geriatric acute care unit: results from a pilot cohort study.

    abstract::Finding a biomarker of long length-of-stay (LOS) would provide a simple solution to target frail older inpatients at such risk. The aim of this study was to determine whether serum 25-hydroxyvitamin D (25OHD) deficiency, defined as serum concentration <25 nmol/L, was associated with long LOS among inpatients admitted ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Beauchet O,Launay CP,Maunoury F,de Decker L,Fantino B,Annweiler C

    更新日期:2013-04-01 00:00:00

  • Association with and predictive capacity of self-perceived risk of falling in recurrent falls in older people: a prospective study.

    abstract:OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Gálvez-Barrón C,Sanguino MJ,Narvaiza L,Cavestany F,Collado I,Macho O,Dapena MD,Rodríguez-Molinero A

    更新日期:2013-10-01 00:00:00

  • Racial variations in self-reported osteoarthritis symptom severity among veterans.

    abstract:BACKGROUND AND AIMS:This study aimed at examining factors related to osteoarthritis (OA) symptom severity in African American and Caucasian veterans (n=202). METHODS:OA symptom severity (lower extremity pain, stiffness, and physical function) was measured by the Western Ontario and McMaster Universities Osteoarthritis...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Golightly YM,Dominick KL

    更新日期:2005-08-01 00:00:00

  • Malnutrition is associated with dynamic physical performance.

    abstract:BACKGROUND:Malnutrition and poor physical performance are both conditions that increase in prevalence with age; however, their interrelation in a clinically relevant population has not been thoroughly studied. AIMS:This study aimed to determine the strength of the association between malnutrition and measures of both ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Ramsey KA,Meskers CGM,Trappenburg MC,Verlaan S,Reijnierse EM,Whittaker AC,Maier AB

    更新日期:2020-06-01 00:00:00

  • Performance on fast- and usual-paced 400-m walk tests in older adults: are they comparable?

    abstract:BACKGROUND AND AIMS:Fast- and usual-paced 400-m walking tests are often used to assess physical fitness or function, respectively, though it is not known how performance converges on these tests. This study aims to determine whether performance on the fast- and usual-paced 400-m walks varies based upon age and physical...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Lange-Maia BS,Newman AB,Strotmeyer ES,Harris TB,Caserotti P,Glynn NW

    更新日期:2015-06-01 00:00:00

  • Morphometric dual-energy X-ray absorptiometry (MXA) for identification of vertebral fractures.

    abstract::Visual identification of vertebral fractures from spinal radiographs makes use of operator expertise in ruling out non-fracture deformities or normal variants. Morphometric X-ray absorptiometry (MXA) has recently been developed to assess vertebral deformity status quantitatively by dual energy X-ray absorptiometry (DX...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Francucci CM,Romagni P,Fiscaletti P,Caudarella R,Boscaro M

    更新日期:2007-06-01 00:00:00

  • Biomarkers for physical frailty and sarcopenia.

    abstract::Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given their high prevalence and association with several adverse outcomes. Nevertheless, the lack of an univocal operational definition for the two conditions has so far hampered their clinical implementation. Existing definitional ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Calvani R,Marini F,Cesari M,Tosato M,Picca A,Anker SD,von Haehling S,Miller RR,Bernabei R,Landi F,Marzetti E,SPRINTT Consortium.

    更新日期:2017-02-01 00:00:00

  • Low systolic blood pressure is associated with impaired cognitive function in the oldest old: longitudinal observations in a population-based sample 80 years and older.

    abstract:BACKGROUND AND AIMS:The primary aim of the present study was to examine whether there is an association between blood pressure and the risk of subsequent cognitive decline in the oldest old. Various factors associated with blood pressure and cognitive function were considered. METHODS:The study comprised 599 individua...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Nilsson SE,Read S,Berg S,Johansson B,Melander A,Lindblad U

    更新日期:2007-02-01 00:00:00

  • Comorbidities, polypharmacy, functionality and nutritional status in Turkish community-dwelling female elderly.

    abstract:BACKGROUND AND AIMS:Most elderly persons live in developing countries where current geriatric epidemiological data are scarce. We aimed to study major comorbidities, polypharmacy, functional and nutritional status in a Turkish community-dwelling female elderly clinic population. METHODS:Female geriatrics outpatient cl...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Bahat G,Tufan F,Bahat Z,Tufan A,Aydin Y,Akpinar TS,Nadir S,Erten N,Karan MA

    更新日期:2014-06-01 00:00:00

  • Motivators for Alzheimer's disease clinical trial participation.

    abstract:BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Bardach SH,Holmes SD,Jicha GA

    更新日期:2018-02-01 00:00:00

  • Step adjustments among young and elderly when walking toward a raised surface.

    abstract:BACKGROUND:Falls among the elderly are often associated with walking on uneven ground. Obstacle negotiation requires both postural reaction strategies and anticipatory strategies which may be impaired with age. Anticipatory strategies are necessary in many daily living situations such as crossing the street and negotia...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Laessoe U,Voigt M

    更新日期:2013-06-01 00:00:00

  • Measurement of lean body mass using bioelectrical impedance analysis: a consideration of the pros and cons.

    abstract::The assessment of body composition has important applications in the evaluation of nutritional status and estimating potential health risks. Bioelectrical impedance analysis (BIA) is a valid method for the assessment of body composition. BIA is an alternative to more invasive and expensive methods like dual-energy X-r...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Sergi G,De Rui M,Stubbs B,Veronese N,Manzato E

    更新日期:2017-08-01 00:00:00

  • Second-order visual sensitivity in the aging population.

    abstract::Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Reynaud A,Tang Y,Zhou Y,Hess RF

    更新日期:2019-05-01 00:00:00

  • Attitudes of neurology specialists toward older adults.

    abstract:OBJECTIVE:Attitude of healthcare providers toward older people is very important in the aging world. Neurologists contact older adults very frequently. We aimed to investigate the attitudes of neurologists toward older adults. MEASUREMENTS:We recorded participants age; sex; duration of clinical practice in neurology; ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Seferoğlu M,Yıldız D,Pekel NB,Güneş A,Yıldız A,Tufan F

    更新日期:2017-08-01 00:00:00

  • Pattern of use and presenting complaints of older patients visiting an Emergency Department in Italy.

    abstract:BACKGROUND AND AIMS:The number of older persons admitted to the Emergency Department (ED) is dramatically increasing due to their complex medical and social problems, which in turn lead to longer clinical evaluation times and increased use of resources compared to younger adults. However, scant data are available for I...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Salvi F,Mattioli A,Giannini E,Vita D,Morichi V,Fallani M,Dessì-Fulgheri P,Cherubini A

    更新日期:2013-10-01 00:00:00

  • Effects of participatory art-based painting workshops in geriatric inpatients: results of a non-randomized open label trial.

    abstract:BACKGROUND:Art-based activities like painting workshops demonstrated health benefits in older individuals living in home care facilities. Few studies examined the effects of painting workshops in geriatric inpatients. AIM:The study aims to examine whether the participation in painting workshops performed in patients a...

    journal_title:Aging clinical and experimental research

    pub_type: 临床试验,杂志文章


    authors: Beauchet O,Lafleur L,Remondière S,Galery K,Vilcocq C,Launay CP

    更新日期:2020-12-01 00:00:00

  • Related factors of cognitive impairment in community-dwelling older adults in Beijing Longitudinal Study of Aging.

    abstract:OBJECTIVES:To investigate the prevalence and related factors of cognitive impairment in community-dwelling older residents in Beijing, China. METHODS:This is a cross-sectional study. A total of 2017 older individuals aged ≥ 60 years from Beijing Longitudinal Study of Aging were included in this study. Information on d...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Han R,Tang Z,Ma L

    更新日期:2019-01-01 00:00:00

  • Predictive value of C-reactive protein and NT-pro-BNP levels in sepsis patients older than 75 years: a prospective, observational study.

    abstract:INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Li H,Shan-Shan Z,Jian-Qiang K,Ling Y,Fang L

    更新日期:2020-03-01 00:00:00

  • Drugs and falls in older people in geriatric care settings.

    abstract:BACKGROUND AND AIMS:Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs. METHODS:This population-based study, with a cross-sectional design, analysed all geriatric c...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Kallin K,Gustafson Y,Sandman PO,Karlsson S

    更新日期:2004-08-01 00:00:00

  • Alternative and complementary therapies in osteoarthritis and cartilage repair.

    abstract::Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审


    authors: Fuggle NR,Cooper C,Oreffo ROC,Price AJ,Kaux JF,Maheu E,Cutolo M,Honvo G,Conaghan PG,Berenbaum F,Branco J,Brandi ML,Cortet B,Veronese N,Kurth AA,Matijevic R,Roth R,Pelletier JP,Martel-Pelletier J,Vlaskovska M,Thoma

    更新日期:2020-04-01 00:00:00

  • In-hospital elderly mortality and associated factors in 12 Italian acute medical units: findings from an exploratory longitudinal study.

    abstract:BACKGROUND:Given the progressive demographic ageing of the population and the National Health System reforms affecting care at the bedside, a periodic re-evaluation of in-hospital mortality rates and associated factors is recommended. AIMS:To describe the occurrence of in-hospital mortality among patients admitted to ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,多中心研究


    authors: Ambrosi E,De Togni S,Guarnier A,Barelli P,Zambiasi P,Allegrini E,Bazoli L,Casson P,Marin M,Padovan M,Picogna M,Taddia P,Salmaso D,Chiari P,Frison T,Marognolli O,Canzan F,Saiani L,Palese A

    更新日期:2017-06-01 00:00:00

  • Mild cognitive impairment, degenerative and vascular dementia as predictors of intra-hospital, short- and long-term mortality in the oldest old.

    abstract:BACKGROUND AND AIMS:The relative weight of various etiologies of dementia and mild cognitive impairment (MCI) as predictors of intra-hospital, short- and long-term mortality in very old acutely ill patients suffering from multiple comorbid conditions remains unclear. We investigated intra-hospital, 1- and 5-year mortal...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Zekry D,Herrmann FR,Graf CE,Giannelli S,Michel JP,Gold G,Krause KH

    更新日期:2011-02-01 00:00:00

  • Platelet-to-lymphocyte ratio relates to poor prognosis in elderly patients with acute myocardial infarction.

    abstract:BACKGROUND:The platelet to lymphocyte ratio (PLR) is a novel biomarker to predict the prognosis of acute myocardial infarction (AMI) patients. AIM:The study aimed to evaluate the in-hospital outcomes of elderly patients with AMI and assessed the prognostic value of PLR on in-hospital adverse events. METHODS:A total o...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Li L,Ma Y,Geng XB,Tan Z,Wang JH,Cui C,Wang HL,Shang XM

    更新日期:2020-04-16 00:00:00

  • Reduced gait and postural stability under challenging conditions in fallers with upper limb fracture.

    abstract:BACKGROUND:While most fractures are caused by falls, not all falls result in fractures. Risk factors for falls are well established, but only weak associations have been demonstrated for risk factors for fractures. Conflicting results on the implication of bone mineral density (BMD) suggest that other risk factors shou...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Langeard A,Pothier K,Chastan N,Marcelli C,Chavoix C,Bessot N

    更新日期:2019-04-01 00:00:00

  • Physical activity among hospitalised older people: insights from upper and lower limb accelerometry.

    abstract:BACKGROUND:Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS:To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Acti...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Lim SER,Dodds R,Bacon D,Sayer AA,Roberts HC

    更新日期:2018-11-01 00:00:00

  • Executive function and life-space mobility in old age.

    abstract:BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Poranen-Clark T,von Bonsdorff MB,Rantakokko M,Portegijs E,Eronen J,Kauppinen M,Eriksson JG,Rantanen T,Viljanen A

    更新日期:2018-02-01 00:00:00

  • Effect of age on treatment, trends and outcome of patients hospitalized with atrial fibrillation: insights from a 20-years registry in a Middle-Eastern country (1991-2010).

    abstract:BACKGROUND:Most studies on atrial fibrillation (AF) epidemiology, treatment, and outcomes have included mainly Caucasians patients. The world literature on AF in other ethnicities is very limited particularly in the elderly. AIMS:The aim of this study was to compare the clinical characteristics, treatment and outcome ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Salam AM,AlBinali HA,Al-Sulaiti EM,Al-Mulla AW,Singh R,Al Suwaidi J

    更新日期:2012-12-01 00:00:00

  • The effect of short-term health promotion intervention on motor function in community-dwelling older adults.

    abstract:BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Kutsuna T,Hiyama Y,Kusaka S,Kusumoto Y,Tsuchiya J,Umeda M,Takahashi T

    更新日期:2019-04-01 00:00:00

  • The role of cognitive reserve in cognitive aging: what we can learn from Parkinson's disease.

    abstract::Parkinson's disease (PD) typically occurs in elderly people and some degree of cognitive impairment is usually present. Cognitive reserve (CR) theory was proposed to explain the discrepancy between the degree of brain pathologies and clinical manifestations. We administered a comprehensive neuropsychological battery t...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章


    authors: Ciccarelli N,Monaco MRL,Fusco D,Vetrano DL,Zuccalà G,Bernabei R,Brandi V,Pisciotta MS,Silveri MC

    更新日期:2018-07-01 00:00:00

  • Effect of a mixed-exercise program on physical capacity and sedentary behavior in older adults during cancer treatments.

    abstract:BACKGROUND:Aging, cancer and its treatment all contribute to increase the risk of deconditioning and sedentary behaviors. Mixed exercise is recognized to counteract the effects of aging and deconditioning as well as improving physical capacity during cancer treatment in adults. AIMS:To determine the impact of a mixed ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验


    authors: Maréchal R,Fontvieille A,Parent-Roberge H,Fülöp T,Riesco E,Pavic M,Dionne IJ

    更新日期:2019-11-01 00:00:00