Abstract:
PURPOSE:The diagnostic value of the neutrophil-to-lymphocyte count ratio (NLR) and the Appendicitis Inflammatory Response (AIR) score for identifying acute appendicitis (AA) perforation in elderly patients in the emergency department (ED) were evaluated. METHODS:A total of 103 patients who were admitted for appendectomy for AA via the ED between January 2012 and December 2014 were reviewed retrospectively. Patients aged 65 and over were included. Patient age, sex, comorbidities, body temperature, clinical findings and initial laboratory results including white blood cell (WBC) count, NLR, serum levels of CRP and total bilirubin (TB) in the ED were assessed, and the AIR score was calculated. RESULTS:Perforation due to AA was identified in 58 (56.3 %) elderly patients. Median WBC count, neutrophil count, CRP and TB were significantly higher in the perforated group compared to the non-perforated group (p = 0.005, p = 0.001, p = 0.004 and p = 0.012) in the ED. The NLR was significantly different in the two groups (perforated vs non-perforated group, 9.5 vs 5.1, p < 0.001). The area under the curve value of NLR was 0.755 (95 % CI 0.660-0.834), and the cutoff value was 5.6 (sensitivity 78.0 % and specificity 65.9 %). In multivariate logistic analysis, NLR > 5.6 [odds ratio (OR) 6.794, p = 0.001] was significant independent factor for AA perforation in elderly patients. The AIR score risk probability did not differ between the two groups of elderly patients (p = 0.094). Twenty-five (42.4 %) patients in the perforated group and five (11.4 %) patients in the non-perforated group were classified as high probability by the modified AIR score including the NLR value (p = 0.001). CONCLUSION:We suggest that the initial NLR in the elderly patient is the most powerful predictive factor for the diagnosis of AA perforation in the ED.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Jung SK,Rhee DY,Lee WJ,Woo SH,Seol SH,Kim DH,Choi SPdoi
10.1007/s40520-016-0584-8subject
Has Abstractpub_date
2017-06-01 00:00:00pages
529-536issue
3eissn
1594-0667issn
1720-8319pii
10.1007/s40520-016-0584-8journal_volume
29pub_type
杂志文章abstract:BACKGROUND:Influence of cognitive intervention programs on brain activity has not been enough explored. AIMS:The aims of the present study were to clarify changes in brain activity from a cognitive intervention program utilizing the board game "Go" and to examine the relationship between brain activity and the acquisi...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01462-6
更新日期:2020-11-01 00:00:00
abstract:INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...
journal_title:Aging clinical and experimental research
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abstract:BACKGROUND:The effectiveness of computer-based cognitive training (CCT) remains controversial, especially in older adults with neurodegenerative diseases. AIMS:To evaluate the efficacy of CCT in patients with Parkinson's disease and mild cognitive impairment (PD-MCI). METHODS:In this randomized controlled trial, 53 p...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01665-2
更新日期:2020-09-08 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0049-2
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:The Short Physical Performance Battery (SPPB) and the De Morton Mobility Index (DEMMI) are two commonly used instruments to assess mobility in older patients. AIMS:To compare the two assessments in acute senior trauma patients with regard to sensitivity to change during an acute care, and prediction of disc...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01249-9
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abstract::Depression is one of the leading causes of suffering in the elderly, but it is often under-diagnosed and under-treated, partly due to the false belief that depression is a common aspect of aging. Depression in the elderly is frequently comorbid with medical illnesses, may often be expressed by somatic complaints, and ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/BF03327382
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abstract:AIM:Falls are a significant problem for older people, but are few studies of the risk of falling in residents of nursing homes in Japan. We aimed to investigate the risk factors for falls and the association of medication use and falls in nursing home residents in Japan. METHODS:This case-control study reviewed the re...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01265-9
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abstract:BACKGROUND AND AIMS:Hip and knee replacements have become increasingly common in the older population but the prevalence of these procedures and the potential impact on functioning towards the end of life have not been previously described. The aim of this study was to estimate the rates and distribution of hip and kne...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324481
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Elderly people experience a gradual loss of muscle strength and a reduction of serum levels of vitamin D and of vitamin D receptor expression in skeletal muscle cells. AIMS:The aim of our study was to evaluate the association among serum levels of 25-hydroxy-vitamin D [25(OH)D3], muscle strength, and physic...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-015-0405-5
更新日期:2015-10-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-014-0227-x
更新日期:2014-12-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0171-1
更新日期:2014-06-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0742-7
更新日期:2018-01-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01642-9
更新日期:2020-06-27 00:00:00
abstract:OBJECTIVES:To investigate the prevalence and related factors of cognitive impairment in community-dwelling older residents in Beijing, China. METHODS:This is a cross-sectional study. A total of 2017 older individuals aged ≥ 60 years from Beijing Longitudinal Study of Aging were included in this study. Information on d...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-018-1067-x
更新日期:2019-09-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/s40520-013-0149-z
更新日期:2014-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.3275/7042
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND AND AIMS:The success of I-131 therapy in geriatric patients who were referred to an endocrinology clinic with toxic nodular goiter and who lived in iodine-deficiency regions was studied. MATERIALS AND METHODS:Patients older than 60 years who received I-131 therapy were included via retrospective data analys...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.3275/8759
更新日期:2012-12-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.3275/8521
更新日期:2012-12-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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journal_title:Aging clinical and experimental research
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doi:10.1007/s40520-018-1087-6
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journal_title:Aging clinical and experimental research
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更新日期:2020-03-11 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2020-09-15 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0060-7
更新日期:2013-08-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324584
更新日期:2005-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2009-06-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:Aging clinical and experimental research
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更新日期:2018-02-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01353-w
更新日期:2020-09-01 00:00:00