Depression in the elderly: new concepts and therapeutic approaches.

abstract：BACKGROUND AND AIMS:The process applied to identify fall risks in frail elderly persons remains a matter of debate. We intended to develop a fall screening instrument for clinically defined subgroups of long-term care residents, to be administered by nursing staff. METHODS:Fall risk indicators were selected by multipl...

journal_title：Aging clinical and experimental research

authors： Becker C,Loy S,Sander S,Nikolaus T,Rissmann U,Kron M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIMS:In order to investigate the relation between personal functional capacity and the physical housing environment during the aging process, the aim of this study was to give a long-term description of person-environmental fit (P-E fit) problems in terms of housing accessibility and ADL dependence among...

journal_title：Aging clinical and experimental research

authors： Werngren-Elgström M,Carlsson G,Iwarsson S

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...

journal_title：Aging clinical and experimental research

authors： Bardach SH,Holmes SD,Jicha GA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Although many older persons choose to postpone retirement, the health consequences of this decision are still debated. This study aimed at determining the impact of continued employment on life-style, well-being, health and survival in a cohort of community-dwelling 70-year-olds. METHODS:A longitud...

journal_title：Aging clinical and experimental research

authors： Hammerman-Rozenberg R,Maaravi Y,Cohen A,Stessman J

更新日期：2005-12-01 00:00:00

abstract：:Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to m...

journal_title：Aging clinical and experimental research

authors： Piarulli G,Rossi A,Zatti G

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Significant correlation has been previously demonstrated between radiographic and clinical diagnoses of knee osteoarthritis (OA); however, the specific findings on clinical examination that relate best to a radiographic diagnosis have not been fully elicited. AIMS:We aimed to explore the relationship betwee...

journal_title：Aging clinical and experimental research

authors： Parsons C,Fuggle NR,Edwards MH,Goulston L,Litwic AE,Jagannath D,van der Pas S,Cooper C,Dennison EM,EPOSA Research Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIM:Several measurements were taken for frailty classification in geriatric population. "Frailty index" is based on "deficits in health," but it is still not available in Italian version. Thus, the aim of the present work was to validate a version of "frailty index" for the Italian geriatric community. ...

journal_title：Aging clinical and experimental research

authors： Abete P,Basile C,Bulli G,Curcio F,Liguori I,Della-Morte D,Gargiulo G,Langellotto A,Testa G,Galizia G,Bonaduce D,Cacciatore F

更新日期：2017-10-01 00:00:00

abstract：AIM:We report 3 cases of spontaneous insufficiency fracture of long bones, to promote awareness of this phenomenon to medical personnel dealing with long-term bedridden patients. METHODS:Cases were analyzed in the light of a literature review. RESULTS:Our patients were all women, who were severely debilitated and had...

journal_title：Aging clinical and experimental research

authors： Manevich D,Brill S,Hershkovitz A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs. METHODS:This population-based study, with a cross-sectional design, analysed all geriatric c...

journal_title：Aging clinical and experimental research

authors： Kallin K,Gustafson Y,Sandman PO,Karlsson S

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA and there is no effective treatment to stop its progression. Current pharmacologic treatments such as analgesics and non-steroidal anti-inflammatory drugs may improve the pain and offer some r...

journal_title：Aging clinical and experimental research

authors： Messina OD,Vidal Wilman M,Vidal Neira LF

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Falls among the elderly are often associated with walking on uneven ground. Obstacle negotiation requires both postural reaction strategies and anticipatory strategies which may be impaired with age. Anticipatory strategies are necessary in many daily living situations such as crossing the street and negotia...

journal_title：Aging clinical and experimental research

authors： Laessoe U,Voigt M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:There is a high burden of antipsychotic use in residential aged care facilities (RACFs) and there is concern regarding potential inappropriate prescribing of antipsychotics in response to mild behavioural symptoms. Antipsychotic use has been associated with a higher risk of mortality in community-dwelling ol...

journal_title：Aging clinical and experimental research

authors： Harrison SL,Sluggett JK,Lang C,Whitehead C,Crotty M,Corlis M,Wesselingh S,Inacio MC

更新日期：2020-03-11 00:00:00

abstract：BACKGROUND AND AIMS:Age-related reductions in strength and power are considered to negatively impact balance control, but the existence of a direct association is still an issue of debate. This is possibly due to the fact that balance assessment is complex, reflects different underlying physiologic mechanisms and invol...

journal_title：Aging clinical and experimental research

authors： Forte R,Boreham CA,De Vito G,Ditroilo M,Pesce C

更新日期：2014-12-01 00:00:00

abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...

journal_title：Aging clinical and experimental research

authors： Belmin J,Bourée P,Camus D,Guiso N,Jeandel C,Trivalle C,Veyssier P

更新日期：2009-06-01 00:00:00

abstract：AIMS:The aim of this pilot study was to examine the effect of a home-made oral supplement on body weight and energy intake of old people residing in a nursing home. METHODS:Sixty-six old (65+ years) nursing home residents were included and divided into three classes according to their Mini Nutritional Assessment (MNA)...

journal_title：Aging clinical and experimental research

authors： Beck AM,Ovesen L,Schroll M

更新日期：2002-06-01 00:00:00

abstract：:Epidemiological studies of suicide in the elderly indicate that, in the last few decades, there has been a relevant increase in suicide rates in old age in a number of Asian and Latin nations, with an almost parallel decrease in Anglo-Saxon counties. Mental disorders, particularly depression, physical illness, persona...

journal_title：Aging clinical and experimental research

authors： De Leo D,Spathonis K

更新日期：2003-04-01 00:00:00

abstract：:New onset epilepsy and seizures are common neurological disorders in aged people, second only to stroke and dementia. They are frequently related to other pathological conditions including stroke, trauma, tumors and neurological diseases whereas in about one-third of cases the origin is unknown. Besides the origin, th...

journal_title：Aging clinical and experimental research

authors： Losi G,Gomez-Gonzalo M,Zonta M,Chiavegato A,Carmignoto G

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Oxidative stress is strongly associated with aging and age-related diseases and plays a crucial role in endothelial dysfunction development. AIM:To better understand the molecular mechanisms of aging and stress response in humans, we examined changes to young and older human endothelial cells over time (72,...

journal_title：Aging clinical and experimental research

authors： Conti V,Corbi G,Simeon V,Russomanno G,Manzo V,Ferrara N,Filippelli A

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Since oral organs function in the first stage of the swallowing process, it is possible that decline in swallowing function can be partly related to oral frailty. AIMS:The purpose of this study was to investigate the association between swallowing function and oral function among community-dwelling elderly ...

journal_title：Aging clinical and experimental research

authors： Takeuchi N,Sawada N,Ekuni D,Morita M

更新日期：2020-04-18 00:00:00

abstract：BACKGROUND AND AIMS:Atrial fibrillation (AF) is the most frequent arrhythmia in elderly patients. Aims of this study were to evaluate the predictors of arterial stiffness after external cardioversion (ECV) of AF and to establish whether a link exists between vascular properties and left atrial diameter (LAD). METHODS:...

journal_title：Aging clinical and experimental research

authors： Fumagalli S,Gabbai D,Nreu B,Roberts AT,Boni S,Ceccofiglio A,Fracchia S,Baldasseroni S,Tarantini F,Marchionni N

更新日期：2014-06-01 00:00:00

abstract：:Anderson-Fabry's disease (AFD) is a rare inborn X-linked sphingolipid storage disorder. Deficient activity of the lysosomal enzyme alpha-galactosidase A (alpha-GAL-A) leads to progressive accumulation of glycosphingolipids within most visceral tissues and body fluids of affected patients, provoking a clinical syndrome...

journal_title：Aging clinical and experimental research

authors： Buechner S,Luzzi C,Mannucci M,Massi D,Borsini W

更新日期：2006-08-01 00:00:00

abstract：:This case report concerns an elderly woman referred with a 6-month history of rising and falling fever in the range 38-40°C. She was examined repeatedly by her family doctor and given various antibiotic treatments before being hospitalized in our geriatric unit. Laboratory tests and microbiological studies led to a di...

journal_title：Aging clinical and experimental research

authors： Ruggiero E,Inelmen EM,Grosso G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Age-related structural alterations in motor units and consequential functional manifestations are asserted to underlie the decline in the ability to finely grade, or control, muscular force in upper extremity musculature of older adults. Functional activities requiring appropriately graded muscular ...

journal_title：Aging clinical and experimental research

authors： Bellew JW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Acetylcholinesterase inhibitor (AChEis) therapy in Alzheimer Disease (AD) has been shown to provide cognitive benefits and to slow progression of the disease. AChEis have also been demonstrated to improve behavioral symptoms, although there seem to be subtle differences in the magnitude of response....

journal_title：Aging clinical and experimental research

authors： Rozzini L,Vicini Chilovi B,Bertoletti E,Trabucchi M,Padovani A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Inappropriate prescribing in elderly patients is a widespread health problem. It is associated with increased drug-related problems and health expenditure. AIMS:To determine the prevalence and types of potentially inappropriate medications (PIM) prescribed to elderly patients with polypharmacy and the facto...

journal_title：Aging clinical and experimental research

authors： Mazhar F,Akram S,Malhi SM,Haider N

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Hip and knee replacements have become increasingly common in the older population but the prevalence of these procedures and the potential impact on functioning towards the end of life have not been previously described. The aim of this study was to estimate the rates and distribution of hip and kne...

journal_title：Aging clinical and experimental research

authors： Melzer D,Guralnik JM,Brock D

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiovascular disease is a major cause of mortality in end-stage renal disease patients (ESRD). The rate of elderly and polypathologic patients in ESRD is increasing. Elevated levels of C-reactive protein (CRP) have been shown to be associated with increased mortality in ESRD patients. The aim of t...

journal_title：Aging clinical and experimental research

authors： Millet C,Bosson JL,Pernod G,Wauters JP,Couturier P,Quesada JL,Zaoui P

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The majority of older adults do not reach the physical activity guidelines. One possible explanation for this may be that older adults overestimate their physical activity levels, because they are unable to identify exercise intensity. METHODS:Forty-four older adults were recruited and randomly assigned int...

journal_title：Aging clinical and experimental research

authors： McLellan AG,Slaght J,Craig CM,Mayo A,Sénéchal M,Bouchard DR

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence and related factors of cognitive impairment in community-dwelling older residents in Beijing, China. METHODS:This is a cross-sectional study. A total of 2017 older individuals aged ≥ 60 years from Beijing Longitudinal Study of Aging were included in this study. Information on d...

journal_title：Aging clinical and experimental research

authors： Han R,Tang Z,Ma L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Monochromatic pulsating light may have effects on wound healing. In an earlier study of grade II ulcers, there was a tendency toward better healing in the phototherapy group (p=0.06). The present study on patients with grade II ulcers was performed to verify these findings. Data from this study were...

journal_title：Aging clinical and experimental research

authors： Dehlin O,Elmståhl S,Gottrup F

更新日期：2007-12-01 00:00:00