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Prospective observational study to evaluate risk factors for falls in institutionalized elderly people: the role of cystatin C.

Abstract：

AIM:To evaluate the role of balance and gait disorders, comorbidities and laboratory abnormalities in the occurrence of falls in an institutionalized elderly population. METHODS:We made a non-interventional, prospective, observational study in elderly institutionalized people. Comorbidities and information on treatments were obtained. Function and cognition were measured using the Katz Index, the Tinetti Balance and Gait, lower extremity function tests and the Mini-Mental test. At the inclusion, the analytical was made including cystatin C. Falls were recorded for 20 months after inclusion. RESULTS:Patients with falls were older (85 ± 7 vs. 82 ± 8, p = 0.04) and more often female (88 vs. 12 %, p = 0.01). Dyslipidemia, hypertension and antihypertensive treatment were associated with an increased risk of falls. Cystatin C was higher in patients with falls (0.96 ± 0.21 vs. 1.12 ± 0.29, p = 0.02). Functional tests showed differences in the Tinetti balance test (15 ± 2 vs. 13 ± 3, p = 0.04) and lower extremity function balance test (2.8 ± 1.2 vs. 2.2 ± 1.2, p = 0.05). The Mini-Mental State Examination (MMSE) scores were worse in patients with falls (22 ± 4 vs. 25 ± 4, p = 0.01). Only female status (6.2, p = 0.03), the MMSE scores (1.2, p = 0.02) and cystatin C (5.3, p = 0.02) were independent risk factors for falls after logistic regression. CONCLUSIONS:Female sex, cognitive impairment and cystatin C were risk factors for falls in non-dependent institutionalized elderly people.

journal_name

Aging Clin Exp Res

journal_title

Aging clinical and experimental research

authors

Peláez VC,Ausín L,Mambrilla MR,Gonzalez-Sagrado M,Pérez Castrillón JL

doi

10.1007/s40520-014-0304-1

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

419-24

issue

4

eissn

1594-0667

issn

1720-8319

journal_volume

27

pub_type

杂志文章

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