Aging-related changes in oxidative stress response of human endothelial cells.

abstract：AIMS:The aim of this pilot study was to examine the effect of a home-made oral supplement on body weight and energy intake of old people residing in a nursing home. METHODS:Sixty-six old (65+ years) nursing home residents were included and divided into three classes according to their Mini Nutritional Assessment (MNA)...

journal_title：Aging clinical and experimental research

authors： Beck AM,Ovesen L,Schroll M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND AND AIMS:An accurate diagnosis of sarcopenia is required. The aim of this study is to correlate the results of two methods to define sarcopenia using cross sectional body composition data, with actual loss of fat free mass. METHODS:Healthy older subjects (926 females and 381 males aged 70 years or more) and...

journal_title：Aging clinical and experimental research

authors： Bunout D,de la Maza MP,Barrera G,Leiva L,Gattas V,Hirsch S

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Although several investigations have tested physical activity a few months or one year after hip fracture, only a few have assessed physical activity shortly after hip fracture. The aim of this study was to evaluate how physical function two weeks after hip fracture operation predicts 12-month morta...

journal_title：Aging clinical and experimental research

authors： Heinonen M,Karppi P,Huusko T,Kautiainen H,Sulkava R

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The incidence and costs of acute myocardial infarction (AMI) in Europe represent a substantial problem due to population aging. METHODS:Between 2001 and 2005, Italian hospitalization records were examined to evaluate hospital admissions and costs of AMI in adults aged ≥ 45 and in elderly people ≥ 65 or ≥ 75...

journal_title：Aging clinical and experimental research

authors： Piscitelli P,Iolascon G,Greco M,Marinelli A,Gimigliano F,Gimigliano R,Gisonni P,Giordano A,Migliore A,Granata M,Tarantino U,Brandi ML,Baggiani A,Distante A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...

journal_title：Aging clinical and experimental research

authors： Gálvez-Barrón C,Sanguino MJ,Narvaiza L,Cavestany F,Collado I,Macho O,Dapena MD,Rodríguez-Molinero A

更新日期：2013-10-01 00:00:00

abstract：:The assessment of body composition has important applications in the evaluation of nutritional status and estimating potential health risks. Bioelectrical impedance analysis (BIA) is a valid method for the assessment of body composition. BIA is an alternative to more invasive and expensive methods like dual-energy X-r...

journal_title：Aging clinical and experimental research

authors： Sergi G,De Rui M,Stubbs B,Veronese N,Manzato E

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Polypharmacy has been associated with worse cognitive performance, but its impact on mild cognitive impairment (MCI) progression to dementia has not been explored. AIMS:The aims of the study were to investigate the association between multidrug regimens and MCI progression, and the possible mediation of dru...

journal_title：Aging clinical and experimental research

authors： Trevisan C,Limongi F,Siviero P,Noale M,Cignarella A,Manzato E,Sergi G,Maggi S

更新日期：2019-11-22 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and significance of the clinical application of ultrasound score in assessing the clinical severity of acute cholecystitis in the elderly. METHODS:Pre-surgery ultrasonography was performed on 72 elderly patients with acute cholecystitis who were scheduled for cholecystectomy to...

journal_title：Aging clinical and experimental research

authors： Zhang L,Han Q,Zhang H,Li D,Yao K

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Quality monitoring has great relevance in stroke care. The Project "How to guarantee adherence to effective interventions in stroke care" aimed to estimate adherence to acute-phase guidelines in stroke care in Italy. METHODS:A prospective observational study was performed in 27 hospitals of 13 Ital...

journal_title：Aging clinical and experimental research

authors： Di Carlo A,Accetta G,Bellan M,Terni G,Lamassa M,Facchini R,Biggeri A,Inzitari D,Ferro S,National Stroke Care Group.

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Inappropriate prescribing in elderly patients is a widespread health problem. It is associated with increased drug-related problems and health expenditure. AIMS:To determine the prevalence and types of potentially inappropriate medications (PIM) prescribed to elderly patients with polypharmacy and the facto...

journal_title：Aging clinical and experimental research

authors： Mazhar F,Akram S,Malhi SM,Haider N

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Although the role of afferent input from cervical muscles on the control of posture and locomotion is recognised, it is surprising that there is an absence of data reporting whether joint position sense at the cervical level is impaired in older healthy adults. The present experiment was designed to...

journal_title：Aging clinical and experimental research

authors： Vuillerme N,Pinsault N,Bouvier B

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Interprofessional collaborative practice (ICP) is currently recommended for the delivery of high-quality integrated care for older people. Frailty prevention and management are key elements to be tackled on a multi-professional level. AIM:This study aims to develop a consensus-based European multi-professio...

journal_title：Aging clinical and experimental research

authors： Roller-Wirnsberger R,Lindner S,Liew A,O'Caoimh R,Koula ML,Moody D,Espinosa JM,van Durme T,Dimitrov P,Benjak T,Nicolaidou E,Hammar T,Vanhecke E,Junius-Walker U,Csizmadia P,Galluzzo L,Macijauskienė J,Salem M,Rietman L,

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:The circadian rhythm of serum thyroid stimulating hormone (TSH) levels in patients with Alzheimer's disease was measured by means of a case-control study. METHODS:Serum samples from cases and controls were collected continuously for 2 days, and then once every 2 h (even number time-point during the first da...

journal_title：Aging clinical and experimental research

authors： Chen JM,Huang CQ,Ai M,Kuang L

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Age-related reductions in strength and power are considered to negatively impact balance control, but the existence of a direct association is still an issue of debate. This is possibly due to the fact that balance assessment is complex, reflects different underlying physiologic mechanisms and invol...

journal_title：Aging clinical and experimental research

authors： Forte R,Boreham CA,De Vito G,Ditroilo M,Pesce C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Whether or not there has been a "compression of morbidity" in older ages has been vividly debated during the last decades. Previous studies have found indications of both improved and deteriorated health among elderly persons. Few studies have analyzed how changes in health indicators are influenced...

journal_title：Aging clinical and experimental research

authors： Wilhelmson K,Allebeck P,Steen B

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Accumulation of aggregated α-synuclein from the enteric nervous system is believed to be involved in the pathogenesis of Parkinson's disease (PD). The appendix contains abundant α-synuclein and lacks a blood-tissue barrier, suggesting that appendectomy might reduce α-synuclein aggregation, and therefore the ...

journal_title：Aging clinical and experimental research

authors： Lu HT,Shen QY,Xie D,Zhao QZ,Xu YM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Falling is a significant concern for many elderly adults but identifying individuals at risk of falling is difficult, and it is not clear how elderly adults adapt to challenging walking. AIMS:The aim of the current study was to determine the effects of walking at non-preferred speeds on the coordination bet...

journal_title：Aging clinical and experimental research

authors： Craig JJ,Bruetsch AP,Huisinga JM

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes...

journal_title：Aging clinical and experimental research

authors： Windhaber T,Koula ML,Ntzani E,Velivasi A,Rizos E,Doumas MT,Pappas EE,Onder G,Vetrano DL,Roudriguez Laso A,Roudriguez Manjas L,Illario M,Roller-Wirnsberger RE,ADVANTAGE JA WP8 group.

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND AIMS:While caloric restriction (CR) is associated with a prolonged lifespan in multiple species by regulating metabolism, a comprehensive profile of metabolism under CR conditions remains largely unclear. Therefore, in this study we aimed to characterize the metabolomic profiling associated with CR using...

journal_title：Aging clinical and experimental research

authors： Zhang Y,Yan S,Gao X,Xiong X,Dai W,Liu X,Li L,Zhang W,Mei C

更新日期：2012-02-01 00:00:00

abstract：:Despite strong evidence for the efficacy of integrated systems, securing the participation of health professionals, particularly primary care physicians (PCPs), has proven difficult. Novel approaches are needed to resolve these problems. We developed a model - COPA - that is based on scientific evidence and an origina...

journal_title：Aging clinical and experimental research

authors： Vedel I,De Stampa M,Bergman H,Ankri J,Cassou B,Mauriat C,Blanchard F,Bagaragaza E,Lapointe L

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Assessment of physical frailty is important among elderly with severe aortic stenosis (AS) when considering treatment. AIMS:We aimed to: (1) investigate the prevalence of physical frailty in older people with severe AS and (2) examine factors related to physical frailty. METHODS:A total of 125 consecutive ...

journal_title：Aging clinical and experimental research

authors： Fukui S,Kawakami M,Otaka Y,Ishikawa A,Mizuno K,Tsuji T,Hayashida K,Inohara T,Yashima F,Liu M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common disease in elderly, characterized by poor bone quality as a result of alterations affecting trabecular bone. However, recent studies have described also an important role of alterations of cortical bone in the physiopathology of osteoporosis. Although dual-energy X-ray absorptiometry...

journal_title：Aging clinical and experimental research

authors： Feola M,Rao C,Tempesta V,Gasbarra E,Tarantino U

更新日期：2015-10-01 00:00:00

abstract：:The occurrence of a given disease in a population is measured by prevalence and incidence. Prevalence reflects the burden of a given disease in a specific population and is calculated as point prevalence or period prevalence. Incidence denotes the number of new cases of a given disease which occur in a cohort of indiv...

journal_title：Aging clinical and experimental research

authors： Tripepi G,Torino C,D'Arrigo G,Bolignano D,Provenzano F,Zoccali C

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS:To examine the effect of predictive factors on institutionalization in hom...

journal_title：Aging clinical and experimental research

authors： Salminen M,Vire J,Viikari L,Vahlberg T,Isoaho H,Lehtonen A,Viitanen M,Arve S,Eloranta S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Given the progressive demographic ageing of the population and the National Health System reforms affecting care at the bedside, a periodic re-evaluation of in-hospital mortality rates and associated factors is recommended. AIMS:To describe the occurrence of in-hospital mortality among patients admitted to ...

journal_title：Aging clinical and experimental research

authors： Ambrosi E,De Togni S,Guarnier A,Barelli P,Zambiasi P,Allegrini E,Bazoli L,Casson P,Marin M,Padovan M,Picogna M,Taddia P,Salmaso D,Chiari P,Frison T,Marognolli O,Canzan F,Saiani L,Palese A

更新日期：2017-06-01 00:00:00

abstract：:Valproate is an important but uncommon cause of drug induced parkinsonism in the elderly. The development of symptoms after valproate onset is unpredictable, and severity of symptoms is unrelated to plasma levels. However, though the majority of cases improve after drug cessation, parkinsonian symptoms can persist and...

journal_title：Aging clinical and experimental research

authors： Athauda D,Batley R,Ellis C

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Sepsis is more common in the elderly. TNF⍺ is recognized as an important mediator in sepsis and Toll-like receptors (TLRs) play an important role in initiating signaling cascades to produce TNF⍺. Little is known about how innate immunity is altered in healthy human aging that predisposes to sepsis. AIMS AND...

journal_title：Aging clinical and experimental research

authors： Bailey KL,Smith LM,Heires AJ,Katafiasz DM,Romberger DJ,LeVan TD

更新日期：2019-09-01 00:00:00

abstract：:This case report concerns an elderly woman referred with a 6-month history of rising and falling fever in the range 38-40°C. She was examined repeatedly by her family doctor and given various antibiotic treatments before being hospitalized in our geriatric unit. Laboratory tests and microbiological studies led to a di...

journal_title：Aging clinical and experimental research

authors： Ruggiero E,Inelmen EM,Grosso G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To evaluate (a) the performance in predicting the presence of bone fractures of trabecular bone score (TBS) and hip structural analysis (HSA) in type 2 diabetic postmenopausal women compared to a control group and (b) the fracture prediction ability of TBS versus Fracture Risk Calculator (FRAX®) as well as whet...

journal_title：Aging clinical and experimental research

authors： Bonaccorsi G,Fila E,Messina C,Maietti E,Ulivieri FM,Caudarella R,Greco P,Guglielmi G

更新日期：2017-10-01 00:00:00

abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...

journal_title：Aging clinical and experimental research

authors： Belmin J,Bourée P,Camus D,Guiso N,Jeandel C,Trivalle C,Veyssier P

更新日期：2009-06-01 00:00:00