Evaluation of renal function in the elderly, not as easy as it seems: a review.

abstract：BACKGROUND AND AIMS:Changes in some rhythmometric parameters have been reported in the elderly as a consequence of both structural and neurochemical changes occurring in the central nervous system. Since alterations of lipid and lipoprotein metabolism are directly involved in several age-related disorders, the aim of t...

journal_title：Aging clinical and experimental research

authors： Trotti R,Rondanelli M,Cuzzoni G,Ferrari E,d'Eril GM

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Functional brain imaging has shown that bilateral brain reorganization may occur after unilateral cerebral damage. The present study searched for evidence of bilateral motor control changes in gait in patients with chronic unilateral stroke. METHODS:Gait variables (temporal and spatial parameters, ...

journal_title：Aging clinical and experimental research

authors： Titianova EB,Peurala SH,Pitkänen K,Tarkka IM

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIMS:This study aimed at examining factors related to osteoarthritis (OA) symptom severity in African American and Caucasian veterans (n=202). METHODS:OA symptom severity (lower extremity pain, stiffness, and physical function) was measured by the Western Ontario and McMaster Universities Osteoarthritis...

journal_title：Aging clinical and experimental research

authors： Golightly YM,Dominick KL

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Acetylcholinesterase inhibitor (AChEis) therapy in Alzheimer Disease (AD) has been shown to provide cognitive benefits and to slow progression of the disease. AChEis have also been demonstrated to improve behavioral symptoms, although there seem to be subtle differences in the magnitude of response....

journal_title：Aging clinical and experimental research

authors： Rozzini L,Vicini Chilovi B,Bertoletti E,Trabucchi M,Padovani A

更新日期：2007-06-01 00:00:00

abstract：:Dysfunctional T-cell immunity contributes to susceptibility to infectious disease in the elderly. A characteristic feature of this "immunosenescence" is the predominance of clonal expansions of CD8 cells and decreased diversity of the T-cell antigen receptor repertoire. Lifelong chronic antigenic stress commonly cause...

journal_title：Aging clinical and experimental research

authors： Pawelec G,Gouttefangeas C

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Cognitive and physical deficits independently raise the risk for negative events in older adults. Less is known about whether their co-occurrence constitutes a distinct risk profile. This study quantifies the association between cognitive impairment, no dementia (CIND), slow walking speed (WS) and their comb...

journal_title：Aging clinical and experimental research

authors： Grande G,Vetrano DL,Fratiglioni L,Marseglia A,Vanacore N,Laukka EJ,Welmer AK,Rizzuto D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Choroidal endothelial dysfunction plays key role in wet-type age-related macular degeneration (AMD). Peripheral vascular endothelial function is not known in wet AMD. OBJECTIVE:We aimed to analyze peripheral vascular endothelial function in cases with wet-type age-related macular degeneration by measuring f...

journal_title：Aging clinical and experimental research

authors： Arifoglu HB,Karatepe Hashas AS,Atas M,Sarli B,Ozkose A,Demircan S

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND AIMS:While caloric restriction (CR) is associated with a prolonged lifespan in multiple species by regulating metabolism, a comprehensive profile of metabolism under CR conditions remains largely unclear. Therefore, in this study we aimed to characterize the metabolomic profiling associated with CR using...

journal_title：Aging clinical and experimental research

authors： Zhang Y,Yan S,Gao X,Xiong X,Dai W,Liu X,Li L,Zhang W,Mei C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIMS:To investigate mortality, determinants of mortality, and time until death among elderly subjects receiving public long-term care. METHODS:This study comprises 626 respondents (age: 65-98 years). Data were collected for two cohorts (2001 and 2002). Cox regression analysis was used to identify determ...

journal_title：Aging clinical and experimental research

authors： Jakobsson U,Hallberg IR

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:While most fractures are caused by falls, not all falls result in fractures. Risk factors for falls are well established, but only weak associations have been demonstrated for risk factors for fractures. Conflicting results on the implication of bone mineral density (BMD) suggest that other risk factors shou...

journal_title：Aging clinical and experimental research

authors： Langeard A,Pothier K,Chastan N,Marcelli C,Chavoix C,Bessot N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Marital and parental role characteristics are important factors in both men and women's health. Most studies to date have either focused on disease specific outcomes or summary measures of self-reported health rather than using functional tests of performance. The goal of this study is to investigat...

journal_title：Aging clinical and experimental research

authors： Guralnik JM,Butterworth S,Patel K,Mishra G,Kuh D

更新日期：2009-04-01 00:00:00

abstract：:The aim of this study was to assess the effectiveness of balance training with somatosensory and neurofeedback training on dynamic and static balance in healthy, elderly adults. The sample group consisted of 45 healthy adults randomly assigned to one of the three test groups: somatosensory, neurofeedback, and a contro...

journal_title：Aging clinical and experimental research

authors： Azarpaikan A,Taheri Torbati H

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication after orthopedic surgery, which is not conducive to the prognosis of the elderly. AIMS:We performed this study to investigate the effects of oxycodone applied for patient-controlled intravenous analgesia (PCIA) on postoperative cognitive fu...

journal_title：Aging clinical and experimental research

authors： Gan J,Tu Q,Miao S,Lei T,Cui X,Yan J,Zhang J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...

journal_title：Aging clinical and experimental research

authors： Rantanen T,Hassandra M,Pynnönen K,Siltanen S,Kokko K,Karavirta L,Kauppinen M,Sipilä S,Saajanaho M,Portegijs E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in...

journal_title：Aging clinical and experimental research

authors： Krumpoch S,Lindemann U,Rappl A,Becker C,Sieber CC,Freiberger E

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND AND AIMS:Glycemic control in geriatric patients with type 2 diabetes (T2DM) remains clinically challenging. The objective of this study was to compare the safety and efficacy of insulin lispro in patients C65 years (geriatric) to those\65 years (non-geriatric), using a metaanalysis of randomized controlled c...

journal_title：Aging clinical and experimental research

authors： Curtis BH,Rees TM,Gaskins KA,Sierra-Johnson J,Liu R,Jiang HH,Holcombe JH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures. OBJECTIVE:To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability amo...

journal_title：Aging clinical and experimental research

authors： Baldursdottir B,Whitney SL,Ramel A,Jonsson PV,Mogensen B,Petersen H,Kristinsdottir EK

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...

journal_title：Aging clinical and experimental research

authors： Ferrara MC,Andreano A,Tassistro E,Rapazzini P,Zurlo A,Volpato S,Mussi C,Corsi M,Lunardelli ML,Martini E,Castoldi G,De Filippi F,Pizzonia M,Monacelli F,Barone A,Pilotto A,March A,Ungar A,Capelli R,Galmarini V,Franz

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:The objective of this article is to review the literature regarding the effectiveness and safety of Nordic walking (NW) in therapeutic rehabilitation in patients of an advanced age. METHODS:Randomized studies comparing NW with different patterns of long-lasting physical rehabilitation in older adults (avera...

journal_title：Aging clinical and experimental research

authors： Skórkowska-Telichowska K,Kropielnicka K,Bulińska K,Pilch U,Woźniewski M,Szuba A,Jasiński R

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Since oral organs function in the first stage of the swallowing process, it is possible that decline in swallowing function can be partly related to oral frailty. AIMS:The purpose of this study was to investigate the association between swallowing function and oral function among community-dwelling elderly ...

journal_title：Aging clinical and experimental research

authors： Takeuchi N,Sawada N,Ekuni D,Morita M

更新日期：2020-04-18 00:00:00

abstract：BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...

journal_title：Aging clinical and experimental research

authors： Poranen-Clark T,von Bonsdorff MB,Rantakokko M,Portegijs E,Eronen J,Kauppinen M,Eriksson JG,Rantanen T,Viljanen A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Elderly people experience a gradual loss of muscle strength and a reduction of serum levels of vitamin D and of vitamin D receptor expression in skeletal muscle cells. AIMS:The aim of our study was to evaluate the association among serum levels of 25-hydroxy-vitamin D [25(OH)D3], muscle strength, and physic...

journal_title：Aging clinical and experimental research

authors： Iolascon G,de Sire A,Calafiore D,Moretti A,Gimigliano R,Gimigliano F

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Age-related reductions in strength and power are considered to negatively impact balance control, but the existence of a direct association is still an issue of debate. This is possibly due to the fact that balance assessment is complex, reflects different underlying physiologic mechanisms and invol...

journal_title：Aging clinical and experimental research

authors： Forte R,Boreham CA,De Vito G,Ditroilo M,Pesce C

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. METHODS:We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Regis...

journal_title：Aging clinical and experimental research

authors： Wändell P,Carlsson AC,Li X,Gasevic D,Sundquist J,Sundquist K

更新日期：2020-11-01 00:00:00

abstract：:Falls in the elderly are very common and represent a serious cause of morbidity, severe disability and death. Impairments of the mechanisms of postural stability with age and the presence of acute and chronic diseases may favour the occurrence of falls in the elderly. Together with the adoption of non-pharmacological ...

journal_title：Aging clinical and experimental research

authors： Gatto S,Gimigliano F,Gimigliano R,Iolascon G

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA and there is no effective treatment to stop its progression. Current pharmacologic treatments such as analgesics and non-steroidal anti-inflammatory drugs may improve the pain and offer some r...

journal_title：Aging clinical and experimental research

authors： Messina OD,Vidal Wilman M,Vidal Neira LF

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Peptydil prolyl cis-trans isomerase (PIN-1), which specifically regulates the conformational changes following phosphorylation of several proteins, targets the inactive hyper-phosphorylated tau on the Thr231-Pro motif and directly restores its biological function. Interestingly, PIN-1 is oxidatively...

journal_title：Aging clinical and experimental research

authors： Arosio B,Segat L,Milanese M,Galimberti L,Calabresi C,Zanetti M,Trabattoni D,Annoni G,Crovella S,Vergani C

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To determine the association between the level of nutritional risk and the mortality of hospitalized patients with atrial fibrillation. METHODS:In a prospective cohort study, we included patients hospitalized with atrial fibrillation in an internal medicine department in 2007. We calculated the nutritional r...

journal_title：Aging clinical and experimental research

authors： Díez-Manglano J,Clemente-Sarasa C

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Diagnosis of dementia is often difficult in subjects with low educational level. Our aim was to evaluate the role of functional performance and the possibility of preferring scores of activities of daily living (ADL) and instrumental activities of daily living (IADL) in screening elderly people for ...

journal_title：Aging clinical and experimental research

authors： Iavarone A,Milan G,Vargas G,Lamenza F,De Falco C,Gallotta G,Postiglione A

更新日期：2007-04-01 00:00:00

abstract：:Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...

journal_title：Aging clinical and experimental research

authors： Fuggle NR,Cooper C,Oreffo ROC,Price AJ,Kaux JF,Maheu E,Cutolo M,Honvo G,Conaghan PG,Berenbaum F,Branco J,Brandi ML,Cortet B,Veronese N,Kurth AA,Matijevic R,Roth R,Pelletier JP,Martel-Pelletier J,Vlaskovska M,Thoma

更新日期：2020-04-01 00:00:00