Abstract：
BACKGROUND AND AIMS:This study aimed at examining factors related to osteoarthritis (OA) symptom severity in African American and Caucasian veterans (n=202). METHODS:OA symptom severity (lower extremity pain, stiffness, and physical function) was measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). We also examined whether racial differences existed when controlling for other important demographic and clinical variables, including age, gender, income, educational level, employment status, marital status, number of years with OA symptoms, location of arthritic joints (hip, knee, back, foot/ankle), use of exercise, and current use of OA medications. Lastly, we examined whether factors associated with self-reported OA symptom severity differed in African American and Caucasian veterans. RESULTS:The mean WOMAC score for African American veterans (on a scale of 0-96) was 54.6 (SD=17.2), and the mean score for Caucasian veterans was 48.4 (SD=17.6; p=0.02). In a multivariable regression model including demographic and clinical variables, African American veterans had significantly higher WOMAC scores than Caucasians (3=0.185, p=0.009). In Caucasian veterans, greater number of years with OA, presence of hip OA, and a low income were associated with greater WOMAC scores. In African Americans, no use of exercise and the presence of OA in the hip or back were associated with greater WOMAC scores. CONCLUSIONS:Among this sample of veterans, African Americans had significantly higher WOMAC scores than Caucasians after controlling for other important demographic and clinical factors. Different and more intense treatment strategies may be needed for African American veterans with OA.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Golightly YM,Dominick KLdoi
10.1007/BF03324608subject
Has Abstractpub_date
2005-08-01 00:00:00pages
264-9issue
4eissn
1594-0667issn
1720-8319pii
2742journal_volume
17pub_type
杂志文章abstract：:Mood disorders are common and often under-recognised in older people whereby, together with the general ageing of the population, they are becoming a significant and growing public health problem worldwide. However, the need to address the problem of late life mood disorders in a real-world setting is met with a surpr...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-013-0149-z
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Fall-induced deaths of elderly people are a major problem. AIM AND METHODS:Using the Official Cause-of-Death Statistics of Finland, we aimed to determine the current trends in the number and age-adjusted incidence (per 100,000 persons) of fall deaths among older Finns by taking into account 50 years or olde...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-0898-9
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Despite differences between the studies regarding methods for estimating low muscle mass, the European Working Group on Sarcopenia in Older People (EWGSOP) recommends use of two standard deviations (SDs) below the reference sex-specific means of healthy young adults. AIMS:The aim of this study was to determ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01448-4
更新日期：2020-09-01 00:00:00
abstract：AIMS:The aim of this pilot study was to examine the effect of a home-made oral supplement on body weight and energy intake of old people residing in a nursing home. METHODS:Sixty-six old (65+ years) nursing home residents were included and divided into three classes according to their Mini Nutritional Assessment (MNA)...
journal_title：Aging clinical and experimental research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF03324439
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND AND AIMS:In order to investigate the relation between personal functional capacity and the physical housing environment during the aging process, the aim of this study was to give a long-term description of person-environmental fit (P-E fit) problems in terms of housing accessibility and ADL dependence among...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03325154
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Frailty is a geriatric syndrome that predicts increased morbidity and mortality. In order to investigate specific immune system modulations that may contribute to frailty, eleven age- and sex-matched pairs of community-dwelling frail and non-frail older adults were identified. METHODS:Peripheral bl...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327392
更新日期：2004-06-01 00:00:00
abstract：:Vascular dementia (VaD) is a general term describing problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage from impaired blood flow to the brain. Cognitive rehabilitation and physical therapy are the mainstays of dementia treatment, although often ineffective because o...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0343-2
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:The platelet to lymphocyte ratio (PLR) is a novel biomarker to predict the prognosis of acute myocardial infarction (AMI) patients. AIM:The study aimed to evaluate the in-hospital outcomes of elderly patients with AMI and assessed the prognostic value of PLR on in-hospital adverse events. METHODS:A total o...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01555-7
更新日期：2020-04-16 00:00:00
abstract：:Alzheimer and Parkinson's diseases are neurodegenerative aging-related pathological conditions, mainly caused by the interplay of genetic and non-genetic factors and whose incidence rate is going to drastically increase given the growing life expectancy. To address these complex multifactorial traits, a systems biolog...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-020-01485-4
更新日期：2020-02-06 00:00:00
abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324906
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND AND AIMS:One of the factors playing a role in both the aging process and the etiopathogenesis of primary hypertension is oxidative stress. The purpose of this work was to estimate the production of nitric oxide (NO), oxidase activity of ceruloplasmin (Cp) and level of malondialdehyde (MDA), the end-product o...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324634
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Polypharmacy has been associated with worse cognitive performance, but its impact on mild cognitive impairment (MCI) progression to dementia has not been explored. AIMS:The aims of the study were to investigate the association between multidrug regimens and MCI progression, and the possible mediation of dru...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01420-2
更新日期：2019-11-22 00:00:00
abstract：BACKGROUND AND AIMS:Obesity and lack of physical exercise characterize increasing numbers of people in Western societies, resulting in increasing morbidity and mortality. Regular physical exercise, on the other hand, has been shown to be beneficial. Beneficial effects have also been shown in laboratory rodent studies--...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327370
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:Muscle weakness and 25-hydroxyvitamin D (25(OH)D) deficiency have been associated with adverse outcomes among older adults. However, little is known about the relationship between clinically relevant muscle weakness and 25(OH)D levels in Ecuador. AIMS:To examine the prevalence of muscle weakness and its ass...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0678-3
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Despite evidence of cognitive impairment and difficulties in performing daily activities among elderly people with major depression, studies implementing objective performance-based evaluation of functional deficits in this patient population are scarce. With the aid of a computerized device we exam...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324787
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:The effectiveness of computer-based cognitive training (CCT) remains controversial, especially in older adults with neurodegenerative diseases. AIMS:To evaluate the efficacy of CCT in patients with Parkinson's disease and mild cognitive impairment (PD-MCI). METHODS:In this randomized controlled trial, 53 p...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01665-2
更新日期：2020-09-08 00:00:00
abstract：BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01239-x
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVES:Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. METHODS:We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Regis...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01449-3
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Malnutrition and poor physical performance are both conditions that increase in prevalence with age; however, their interrelation in a clinically relevant population has not been thoroughly studied. AIMS:This study aimed to determine the strength of the association between malnutrition and measures of both ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01295-3
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND AND AIMS:Gender and age effect on brain morphology have been extensively investigated. However, the great variety in methods applied to morphology partly explain the conflicting results of linear patterns of tissue changes and lateral asymmetry in men and women. The aim of the present study was to assess the...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324618
更新日期：2005-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Monochromatic pulsating light may have effects on wound healing. In an earlier study of grade II ulcers, there was a tendency toward better healing in the phototherapy group (p=0.06). The present study on patients with grade II ulcers was performed to verify these findings. Data from this study were...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/BF03324734
更新日期：2007-12-01 00:00:00
abstract：:In severe osteoporosis with recent vertebral compression fracture, drug treatment with anabolic agent in the first 18 months can stimulate the healing process and reduce the rate of progression, preventing new fractures and improving the quality of life of the patient. The sequential therapy with bisphosphonates for a...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND AND AIMS:The success of I-131 therapy in geriatric patients who were referred to an endocrinology clinic with toxic nodular goiter and who lived in iodine-deficiency regions was studied. MATERIALS AND METHODS:Patients older than 60 years who received I-131 therapy were included via retrospective data analys...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.3275/8759
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Age-related structural alterations in motor units and consequential functional manifestations are asserted to underlie the decline in the ability to finely grade, or control, muscular force in upper extremity musculature of older adults. Functional activities requiring appropriately graded muscular ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324415
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0130-x
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-0994-x
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Significant correlation has been previously demonstrated between radiographic and clinical diagnoses of knee osteoarthritis (OA); however, the specific findings on clinical examination that relate best to a radiographic diagnosis have not been fully elicited. AIMS:We aimed to explore the relationship betwee...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0847-z
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Multiple chronic conditions affect people's health-related quality of life (QoL) and the distributions of the conditions may differ between genders. Our goal was to examine gender differences in chronic conditions and QoL among community-living elderly in Taiwan and to examine whether differences in QoL betw...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1099-2
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:SARC-F is a 5-item, self-administered questionnaire developed to screen sarcopenia. To date, no Japanese version of the SARC-F has been developed. AIMS:To create a Japanese version of the SARC-F (SARC-F-J), a questionnaire for diabetic patients, and to investigate its reliability and validity. METHODS:This...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0668-5
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Choroidal endothelial dysfunction plays key role in wet-type age-related macular degeneration (AMD). Peripheral vascular endothelial function is not known in wet AMD. OBJECTIVE:We aimed to analyze peripheral vascular endothelial function in cases with wet-type age-related macular degeneration by measuring f...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0377-5
更新日期：2016-10-01 00:00:00
