Abstract：
BACKGROUND AND AIMS:The success of I-131 therapy in geriatric patients who were referred to an endocrinology clinic with toxic nodular goiter and who lived in iodine-deficiency regions was studied. MATERIALS AND METHODS:Patients older than 60 years who received I-131 therapy were included via retrospective data analyses. Fifty-nine patients between 60 and 82 years of age were enrolled in the study. The patients received an oral capsular form of I-131 (10-25 mCi) and were followed up for 1 year with clinical and laboratory results. Euthyroid or hypothyroid status at the end of the year after treatment was deemed to be a response to treatment. RESULTS:Of the 21 (36%) male and 38 (64%) female patients, 29 (49%) had a solitary toxic nodule and 30 (51%) had toxic multinodular goiter. Twenty-nine (49%) of the patients received propylthiouracil therapy. At the end of the year, 38 (64%) patients were euthyroid, 11 (19%) were hypothyroid, and 10 (17%) were thyrotoxic. Forty-nine (83%) patients who were euthyroid and hypothyroid were considered responders. CONCLUSION:Geriatric patients with toxic nodular goiter were shown to have a high response rate to I-131 therapy. Thus, we suggest that radioactive iodine treatment should be the first-line treatment in these patients.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Erkan ME,Demirin H,Aşik M,Celbek G,Yildirim M,Aydin Y,Güngör A,Doğan ASdoi
10.3275/8759subject
Has Abstractpub_date
2012-12-01 00:00:00pages
714-7issue
6eissn
1594-0667issn
1720-8319pii
8759journal_volume
24pub_type
杂志文章abstract：BACKGROUND AND AIMS:Quality monitoring has great relevance in stroke care. The Project "How to guarantee adherence to effective interventions in stroke care" aimed to estimate adherence to acute-phase guidelines in stroke care in Italy. METHODS:A prospective observational study was performed in 27 hospitals of 13 Ital...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0171-1
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility and significance of the clinical application of ultrasound score in assessing the clinical severity of acute cholecystitis in the elderly. METHODS:Pre-surgery ultrasonography was performed on 72 elderly patients with acute cholecystitis who were scheduled for cholecystectomy to...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-014-0236-9
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01239-x
更新日期：2020-04-01 00:00:00
abstract：AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01715-9
更新日期：2020-09-25 00:00:00
abstract：:Alzheimer and Parkinson's diseases are neurodegenerative aging-related pathological conditions, mainly caused by the interplay of genetic and non-genetic factors and whose incidence rate is going to drastically increase given the growing life expectancy. To address these complex multifactorial traits, a systems biolog...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-020-01485-4
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abstract：BACKGROUND:Art-based activities like painting workshops demonstrated health benefits in older individuals living in home care facilities. Few studies examined the effects of painting workshops in geriatric inpatients. AIM:The study aims to examine whether the participation in painting workshops performed in patients a...
journal_title：Aging clinical and experimental research
pub_type： 临床试验,杂志文章
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abstract：BACKGROUND:Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA and there is no effective treatment to stop its progression. Current pharmacologic treatments such as analgesics and non-steroidal anti-inflammatory drugs may improve the pain and offer some r...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01191-w
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-013-0086-x
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abstract：BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...
journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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abstract：INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-014-0229-8
更新日期：2014-06-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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abstract：:Finding a biomarker of long length-of-stay (LOS) would provide a simple solution to target frail older inpatients at such risk. The aim of this study was to determine whether serum 25-hydroxyvitamin D (25OHD) deficiency, defined as serum concentration <25 nmol/L, was associated with long LOS among inpatients admitted ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0010-4
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:Diverticular disease of the colon also affects older people. Generally, older patients with diverticulitis may be regarded as too risky to undergo surgery. This retroprospective multicentric observational study aims to assess the safety and benefits of laparoscopic peritoneal lavage (LPL) in elderly patients...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,多中心研究
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更新日期：2017-02-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0173-z
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0130-x
更新日期：2013-10-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0678-3
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Statins therapy in the secondary prevention of coronary artery disease (CAD) is associated with a lower risk of adverse cardiovascular events. However, little is known regarding the association of elderly patients with nutritional risk on statin therapy. AIMS:To investigate whether older patients with CAD w...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0881-x
更新日期：2018-09-01 00:00:00
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doi：10.1007/s40520-015-0357-9
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abstract：:Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given their high prevalence and association with several adverse outcomes. Nevertheless, the lack of an univocal operational definition for the two conditions has so far hampered their clinical implementation. Existing definitional ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
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更新日期：2017-08-01 00:00:00
abstract：AIMS:1) to evaluate the prevalence of diabetes mellitus (DM) in a geriatric ward; 2) to assess the efficacy and safety of insulin analogs in elderly inpatients over 65 years of age. METHODS:We analysed the medical records of 1851 elderly inpatients admitted to our geriatric clinic from March 2009 to September 2011, to...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND AND AIMS:Although the role of afferent input from cervical muscles on the control of posture and locomotion is recognised, it is surprising that there is an absence of data reporting whether joint position sense at the cervical level is impaired in older healthy adults. The present experiment was designed to...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324868
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The majority of older adults do not reach the physical activity guidelines. One possible explanation for this may be that older adults overestimate their physical activity levels, because they are unable to identify exercise intensity. METHODS:Forty-four older adults were recruited and randomly assigned int...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0746-3
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Frailty is a public health concern in the ageing population. Little is known about the role of gender in the relationship between frailty and health care utilization in older adults. AIMS:The study aims to examine gender differences in the association between different frailty status and health care utiliza...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-019-01410-4
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND AND AIMS:The Charlson Comorbidity Index (CCI) is the most widely used assessment tool to report the presence of comorbid conditions. The Barthel index (BI) is used to measure performance in activities of daily living. We prospectively investigated the performance of CCI or BI to predict length of hospital st...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1067-x
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND AND AIMS:Cardiovascular disease is a major cause of mortality in end-stage renal disease patients (ESRD). The rate of elderly and polypathologic patients in ESRD is increasing. Elevated levels of C-reactive protein (CRP) have been shown to be associated with increased mortality in ESRD patients. The aim of t...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03325234
更新日期：2011-10-01 00:00:00
abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324906
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND AND AIMS:Frailty is a geriatric syndrome that predicts increased morbidity and mortality. In order to investigate specific immune system modulations that may contribute to frailty, eleven age- and sex-matched pairs of community-dwelling frail and non-frail older adults were identified. METHODS:Peripheral bl...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327392
更新日期：2004-06-01 00:00:00
